Adrafinil

DB08925

small molecule withdrawn

Deskripsi

Adrafinil is a mild central nervous system stimulating drug typically employed to relieve excessive sleepiness and inattention in geriatric patients. It is also been used off-label to prevent fatigue or falling asleep for extended periods of time. Adrafinil does not currently have FDA approval and is thus unregulated in the United States. It was marketed in France and elsewhere in Europe under the trade name Olmifon until September 2011 when France's FDA equivalent reassessed the drug and withdrew marketing permission. Adrafinil is metabolized to modafinil.

Struktur Molekul 2D

Berat 289.35
Wujud solid

Peta Jejaring Molekuler
Legenda: ObatTargetGenEnzim(Panah → menunjukkan arah efek / relasi)TransporterCarrier

Profil Farmakokinetik

Waktu Paruh (Half-Life) -
Volume Distribusi -
Klirens (Clearance) -

Absorpsi

Data absorpsi tidak tersedia.

Metabolisme

Data metabolisme tidak tersedia.

Rute Eliminasi

Data eliminasi belum tersedia.

Interaksi Obat

671 Data
Valsartan Adrafinil may decrease the antihypertensive activities of Valsartan.
Ramipril Adrafinil may decrease the antihypertensive activities of Ramipril.
Reserpine Adrafinil may decrease the antihypertensive activities of Reserpine.
Remikiren Adrafinil may decrease the antihypertensive activities of Remikiren.
Torasemide Adrafinil may decrease the antihypertensive activities of Torasemide.
Isradipine Adrafinil may decrease the antihypertensive activities of Isradipine.
Olmesartan Adrafinil may decrease the antihypertensive activities of Olmesartan.
Chlorthalidone Adrafinil may decrease the antihypertensive activities of Chlorthalidone.
Nitroprusside Adrafinil may decrease the antihypertensive activities of Nitroprusside.
Diltiazem Adrafinil may decrease the antihypertensive activities of Diltiazem.
Minoxidil Adrafinil may decrease the antihypertensive activities of Minoxidil.
Treprostinil Adrafinil may decrease the antihypertensive activities of Treprostinil.
Amlodipine Adrafinil may decrease the antihypertensive activities of Amlodipine.
Nimodipine Adrafinil may decrease the antihypertensive activities of Nimodipine.
Nisoldipine Adrafinil may decrease the antihypertensive activities of Nisoldipine.
Bendroflumethiazide Adrafinil may decrease the antihypertensive activities of Bendroflumethiazide.
Fosinopril Adrafinil may decrease the antihypertensive activities of Fosinopril.
Trandolapril Adrafinil may decrease the antihypertensive activities of Trandolapril.
Metolazone Adrafinil may decrease the antihypertensive activities of Metolazone.
Lercanidipine Adrafinil may decrease the antihypertensive activities of Lercanidipine.
Benazepril Adrafinil may decrease the antihypertensive activities of Benazepril.
Bosentan Adrafinil may decrease the antihypertensive activities of Bosentan.
Enalapril Adrafinil may decrease the antihypertensive activities of Enalapril.
Cyclothiazide Adrafinil may decrease the antihypertensive activities of Cyclothiazide.
Candoxatril Adrafinil may decrease the antihypertensive activities of Candoxatril.
Mecamylamine Adrafinil may decrease the antihypertensive activities of Mecamylamine.
Losartan Adrafinil may decrease the antihypertensive activities of Losartan.
Moexipril Adrafinil may decrease the antihypertensive activities of Moexipril.
Eplerenone Adrafinil may decrease the antihypertensive activities of Eplerenone.
Lisinopril Adrafinil may decrease the antihypertensive activities of Lisinopril.
Nitroglycerin Adrafinil may decrease the antihypertensive activities of Nitroglycerin.
Metyrosine Adrafinil may decrease the antihypertensive activities of Metyrosine.
Hydroflumethiazide Adrafinil may decrease the antihypertensive activities of Hydroflumethiazide.
Cryptenamine Adrafinil may decrease the antihypertensive activities of Cryptenamine.
Perindopril Adrafinil may decrease the antihypertensive activities of Perindopril.
Candesartan cilexetil Adrafinil may decrease the antihypertensive activities of Candesartan cilexetil.
Fenoldopam Adrafinil may decrease the antihypertensive activities of Fenoldopam.
Indapamide Adrafinil may decrease the antihypertensive activities of Indapamide.
Tadalafil Adrafinil may decrease the antihypertensive activities of Tadalafil.
Eprosartan Adrafinil may decrease the antihypertensive activities of Eprosartan.
Chlorothiazide Adrafinil may decrease the antihypertensive activities of Chlorothiazide.
Quinapril Adrafinil may decrease the antihypertensive activities of Quinapril.
Telmisartan Adrafinil may decrease the antihypertensive activities of Telmisartan.
Methyldopa Adrafinil may decrease the antihypertensive activities of Methyldopa.
Hydrochlorothiazide Adrafinil may decrease the antihypertensive activities of Hydrochlorothiazide.
Trichlormethiazide Adrafinil may decrease the antihypertensive activities of Trichlormethiazide.
Irbesartan Adrafinil may decrease the antihypertensive activities of Irbesartan.
Nitrendipine Adrafinil may decrease the antihypertensive activities of Nitrendipine.
Deserpidine Adrafinil may decrease the antihypertensive activities of Deserpidine.
Pentolinium Adrafinil may decrease the antihypertensive activities of Pentolinium.
Trimethaphan Adrafinil may decrease the antihypertensive activities of Trimethaphan.
Diazoxide Adrafinil may decrease the antihypertensive activities of Diazoxide.
Captopril Adrafinil may decrease the antihypertensive activities of Captopril.
Epoprostenol Adrafinil may decrease the antihypertensive activities of Epoprostenol.
Bepridil Adrafinil may decrease the antihypertensive activities of Bepridil.
Hydralazine Adrafinil may decrease the antihypertensive activities of Hydralazine.
Polythiazide Adrafinil may decrease the antihypertensive activities of Polythiazide.
Cilazapril Adrafinil may decrease the antihypertensive activities of Cilazapril.
Saprisartan Adrafinil may decrease the antihypertensive activities of Saprisartan.
Spirapril Adrafinil may decrease the antihypertensive activities of Spirapril.
Mibefradil Adrafinil may decrease the antihypertensive activities of Mibefradil.
Tienilic acid Adrafinil may decrease the antihypertensive activities of Tienilic acid.
Debrisoquine Adrafinil may decrease the antihypertensive activities of Debrisoquine.
Sitaxentan Adrafinil may decrease the antihypertensive activities of Sitaxentan.
Ambrisentan Adrafinil may decrease the antihypertensive activities of Ambrisentan.
Diethylnorspermine Adrafinil may decrease the antihypertensive activities of Diethylnorspermine.
Nilvadipine Adrafinil may decrease the antihypertensive activities of Nilvadipine.
Pinacidil Adrafinil may decrease the antihypertensive activities of Pinacidil.
Temocapril Adrafinil may decrease the antihypertensive activities of Temocapril.
Riociguat Adrafinil may decrease the antihypertensive activities of Riociguat.
Macitentan Adrafinil may decrease the antihypertensive activities of Macitentan.
Hexamethonium Adrafinil may decrease the antihypertensive activities of Hexamethonium.
Aliskiren Adrafinil may decrease the antihypertensive activities of Aliskiren.
Nicorandil Adrafinil may decrease the antihypertensive activities of Nicorandil.
Efonidipine Adrafinil may decrease the antihypertensive activities of Efonidipine.
Lacidipine Adrafinil may decrease the antihypertensive activities of Lacidipine.
Manidipine Adrafinil may decrease the antihypertensive activities of Manidipine.
Rauwolfia serpentina root Adrafinil may decrease the antihypertensive activities of Rauwolfia serpentina root.
Enalaprilat Adrafinil may decrease the antihypertensive activities of Enalaprilat.
Selexipag Adrafinil may decrease the antihypertensive activities of Selexipag.
Angiotensin 1-7 Adrafinil may decrease the antihypertensive activities of Angiotensin 1-7.
Imidapril Adrafinil may decrease the antihypertensive activities of Imidapril.
BQ-123 Adrafinil may decrease the antihypertensive activities of BQ-123.
Tetrahydropalmatine Adrafinil may decrease the antihypertensive activities of Tetrahydropalmatine.
Cicletanine Adrafinil may decrease the antihypertensive activities of Cicletanine.
Dihydralazine Adrafinil may decrease the antihypertensive activities of Dihydralazine.
Zofenopril Adrafinil may decrease the antihypertensive activities of Zofenopril.
Guanoxan Adrafinil may decrease the antihypertensive activities of Guanoxan.
Delapril Adrafinil may decrease the antihypertensive activities of Delapril.
Vincamine Adrafinil may decrease the antihypertensive activities of Vincamine.
Linsidomine Adrafinil may decrease the antihypertensive activities of Linsidomine.
Guanoxabenz Adrafinil may decrease the antihypertensive activities of Guanoxabenz.
Tolonidine Adrafinil may decrease the antihypertensive activities of Tolonidine.
Endralazine Adrafinil may decrease the antihypertensive activities of Endralazine.
Cadralazine Adrafinil may decrease the antihypertensive activities of Cadralazine.
Cyclopenthiazide Adrafinil may decrease the antihypertensive activities of Cyclopenthiazide.
Bietaserpine Adrafinil may decrease the antihypertensive activities of Bietaserpine.
Guanazodine Adrafinil may decrease the antihypertensive activities of Guanazodine.
Methoserpidine Adrafinil may decrease the antihypertensive activities of Methoserpidine.
Guanoclor Adrafinil may decrease the antihypertensive activities of Guanoclor.

Referensi & Sumber

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Contoh Produk & Brand

Produk: 0 • International brands: 1
International Brands
  • Olmifon — Cephalon

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