Peringatan Keamanan

Oral (LD50): Acute: 142 mg/kg Rat. 135 mg/kg Mouse. DUST (LC50): Acute: 209 mg/m 2 hours Rat.

Chloropyramine

DB08800

small molecule experimental

Deskripsi

Chlorpyramine is a first generation antihistamine used in Eastern European countries to treat bronchial asthma as well as allergice rhinitis, allergic conjunctivitis, and other allergic reactions. It is also indicated for Quincke's edema, allergic reactions to insect bites, food and drug allergies, and anaphylactic shock.

Struktur Molekul 2D

Berat 289.803
Wujud solid

Peta Jejaring Molekuler
Legenda: ObatTargetGenEnzim(Panah → menunjukkan arah efek / relasi)TransporterCarrier

Profil Farmakokinetik

Waktu Paruh (Half-Life) -
Volume Distribusi -
Klirens (Clearance) -

Absorpsi

Data absorpsi tidak tersedia.

Metabolisme

Data metabolisme tidak tersedia.

Rute Eliminasi

Data eliminasi belum tersedia.

Interaksi Obat

39 Data
Benzylpenicilloyl polylysine Chloropyramine may decrease effectiveness of Benzylpenicilloyl polylysine as a diagnostic agent.
Betahistine The therapeutic efficacy of Betahistine can be decreased when used in combination with Chloropyramine.
Hyaluronidase (ovine) The therapeutic efficacy of Hyaluronidase (ovine) can be decreased when used in combination with Chloropyramine.
Hyaluronidase (human recombinant) The therapeutic efficacy of Hyaluronidase (human recombinant) can be decreased when used in combination with Chloropyramine.
Hyaluronidase The therapeutic efficacy of Hyaluronidase can be decreased when used in combination with Chloropyramine.
Amphetamine Amphetamine may decrease the sedative activities of Chloropyramine.
Phentermine Phentermine may decrease the sedative activities of Chloropyramine.
Pseudoephedrine Pseudoephedrine may decrease the sedative activities of Chloropyramine.
Benzphetamine Benzphetamine may decrease the sedative activities of Chloropyramine.
Diethylpropion Diethylpropion may decrease the sedative activities of Chloropyramine.
Lisdexamfetamine Lisdexamfetamine may decrease the sedative activities of Chloropyramine.
Mephentermine Mephentermine may decrease the sedative activities of Chloropyramine.
MMDA MMDA may decrease the sedative activities of Chloropyramine.
Midomafetamine Midomafetamine may decrease the sedative activities of Chloropyramine.
2,5-Dimethoxy-4-ethylamphetamine 2,5-Dimethoxy-4-ethylamphetamine may decrease the sedative activities of Chloropyramine.
4-Bromo-2,5-dimethoxyamphetamine 4-Bromo-2,5-dimethoxyamphetamine may decrease the sedative activities of Chloropyramine.
Tenamfetamine Tenamfetamine may decrease the sedative activities of Chloropyramine.
Chlorphentermine Chlorphentermine may decrease the sedative activities of Chloropyramine.
Methylenedioxyethamphetamine Methylenedioxyethamphetamine may decrease the sedative activities of Chloropyramine.
Dextroamphetamine Dextroamphetamine may decrease the sedative activities of Chloropyramine.
Metamfetamine Metamfetamine may decrease the sedative activities of Chloropyramine.
Iofetamine I-123 Iofetamine I-123 may decrease the sedative activities of Chloropyramine.
Ritobegron Ritobegron may decrease the sedative activities of Chloropyramine.
Mephedrone Mephedrone may decrease the sedative activities of Chloropyramine.
Methoxyphenamine Methoxyphenamine may decrease the sedative activities of Chloropyramine.
Gepefrine Gepefrine may decrease the sedative activities of Chloropyramine.
2,5-Dimethoxy-4-ethylthioamphetamine 2,5-Dimethoxy-4-ethylthioamphetamine may decrease the sedative activities of Chloropyramine.
Phendimetrazine Phendimetrazine may decrease the sedative activities of Chloropyramine.
Pitolisant The therapeutic efficacy of Pitolisant can be decreased when used in combination with Chloropyramine.
Norepinephrine The therapeutic efficacy of Norepinephrine can be increased when used in combination with Chloropyramine.
Epinephrine The therapeutic efficacy of Epinephrine can be increased when used in combination with Chloropyramine.
Droxidopa The therapeutic efficacy of Droxidopa can be increased when used in combination with Chloropyramine.
Levonordefrin The therapeutic efficacy of Levonordefrin can be increased when used in combination with Chloropyramine.
Protokylol The therapeutic efficacy of Protokylol can be increased when used in combination with Chloropyramine.
Racepinephrine The therapeutic efficacy of Racepinephrine can be increased when used in combination with Chloropyramine.
Theodrenaline The therapeutic efficacy of Theodrenaline can be increased when used in combination with Chloropyramine.
Deoxyepinephrine The therapeutic efficacy of Deoxyepinephrine can be increased when used in combination with Chloropyramine.
Ephedrine The therapeutic efficacy of Ephedrine can be increased when used in combination with Chloropyramine.
Hyoscyamine Chloropyramine may increase the anticholinergic activities of Hyoscyamine.

Target Protein

Histamine H1 receptor HRH1

Referensi & Sumber

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Contoh Produk & Brand

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Sekuens Gen/Protein (FASTA)

Sekuens dimuat saat dibutuhkan agar halaman tetap ringan.
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