A key intermediate in metabolism. It is an acid compound found in citrus fruits. The salts of citric acid (citrates) can be used as anticoagulants due to their calcium-chelating ability.
Citric acid is one of the active ingredients in Phexxi, a non-hormonal contraceptive agent that was approved by the FDA on May 2020.L14120 It is also used in combination with magnesium oxide to form magnesium citrate, an osmotic laxative.L43832
Fitur visualisasi ini dikembangkan menggunakan pendekatan Graph Theory untuk memetakan hubungan polifarmasi dan molekuler. Entitas (Obat, Target, Gen) direpresentasikan sebagai Simpul (Nodes), sedangkan hubungan biologisnya sebagai Sisi (Edges).
drugbank-id dan name pada skema XML DrugBank.targets/target yang memuat polipeptida sasaran.gene-name dan varian snp-effects.Tata letak grafik menggunakan algoritma Force-Directed Graph (Barnes-Hut). Model fisika ini menerapkan gaya tolak-menolak antar simpul (Gravitasi: -3000) agar tidak tumpang tindih, serta gaya pegas (Spring: 0.04) pada garis penghubung untuk fleksibilitas interaksi.
| Chlorpropamide | Citric acid may decrease the excretion rate of Chlorpropamide which could result in a higher serum level. |
| Mecamylamine | Citric acid may increase the excretion rate of Mecamylamine which could result in a lower serum level and potentially a reduction in efficacy. |
| Technetium Tc-99m oxidronate | Citric acid may decrease effectiveness of Technetium Tc-99m oxidronate as a diagnostic agent. |
| Amphetamine | The excretion of Amphetamine can be decreased when combined with Citric acid. |
| Phentermine | The excretion of Phentermine can be decreased when combined with Citric acid. |
| Pseudoephedrine | The excretion of Pseudoephedrine can be decreased when combined with Citric acid. |
| Benzphetamine | The excretion of Benzphetamine can be decreased when combined with Citric acid. |
| Diethylpropion | The excretion of Diethylpropion can be decreased when combined with Citric acid. |
| Lisdexamfetamine | The serum concentration of Lisdexamfetamine can be increased when it is combined with Citric acid. |
| Mephentermine | The excretion of Mephentermine can be decreased when combined with Citric acid. |
| MMDA | The excretion of MMDA can be decreased when combined with Citric acid. |
| Midomafetamine | The excretion of Midomafetamine can be decreased when combined with Citric acid. |
| 2,5-Dimethoxy-4-ethylamphetamine | The excretion of 2,5-Dimethoxy-4-ethylamphetamine can be decreased when combined with Citric acid. |
| 4-Bromo-2,5-dimethoxyamphetamine | The excretion of 4-Bromo-2,5-dimethoxyamphetamine can be decreased when combined with Citric acid. |
| Tenamfetamine | The excretion of Tenamfetamine can be decreased when combined with Citric acid. |
| Chlorphentermine | The excretion of Chlorphentermine can be decreased when combined with Citric acid. |
| Methylenedioxyethamphetamine | The excretion of Methylenedioxyethamphetamine can be decreased when combined with Citric acid. |
| Dextroamphetamine | The excretion of Dextroamphetamine can be decreased when combined with Citric acid. |
| Metamfetamine | The excretion of Metamfetamine can be decreased when combined with Citric acid. |
| Iofetamine I-123 | The excretion of Iofetamine I-123 can be decreased when combined with Citric acid. |
| Ritobegron | The excretion of Ritobegron can be decreased when combined with Citric acid. |
| Mephedrone | The excretion of Mephedrone can be decreased when combined with Citric acid. |
| Methoxyphenamine | The excretion of Methoxyphenamine can be decreased when combined with Citric acid. |
| Gepefrine | The excretion of Gepefrine can be decreased when combined with Citric acid. |
| 2,5-Dimethoxy-4-ethylthioamphetamine | The excretion of 2,5-Dimethoxy-4-ethylthioamphetamine can be decreased when combined with Citric acid. |
| Phendimetrazine | The excretion of Phendimetrazine can be decreased when combined with Citric acid. |
| Doxycycline | The therapeutic efficacy of Doxycycline can be decreased when used in combination with Citric acid. |
| Lymecycline | The therapeutic efficacy of Lymecycline can be decreased when used in combination with Citric acid. |
| Clomocycline | The therapeutic efficacy of Clomocycline can be decreased when used in combination with Citric acid. |
| Tigecycline | The therapeutic efficacy of Tigecycline can be decreased when used in combination with Citric acid. |
| Oxytetracycline | The therapeutic efficacy of Oxytetracycline can be decreased when used in combination with Citric acid. |
| Demeclocycline | The therapeutic efficacy of Demeclocycline can be decreased when used in combination with Citric acid. |
| Tetracycline | The therapeutic efficacy of Tetracycline can be decreased when used in combination with Citric acid. |
| Metacycline | The therapeutic efficacy of Metacycline can be decreased when used in combination with Citric acid. |
| Minocycline | The therapeutic efficacy of Minocycline can be decreased when used in combination with Citric acid. |
| Rolitetracycline | The therapeutic efficacy of Rolitetracycline can be decreased when used in combination with Citric acid. |
| Sarecycline | The therapeutic efficacy of Sarecycline can be decreased when used in combination with Citric acid. |
| Eravacycline | The therapeutic efficacy of Eravacycline can be decreased when used in combination with Citric acid. |
| Omadacycline | The therapeutic efficacy of Omadacycline can be decreased when used in combination with Citric acid. |
| Penimepicycline | The therapeutic efficacy of Penimepicycline can be decreased when used in combination with Citric acid. |
| Memantine | The excretion of Memantine can be decreased when combined with Citric acid. |