Prasterone, also known as dehydroepiandrosterone (DHEA) is a major C19 steroid produced by the adrenal cortex. It is also produced in small quantities in the testis and the ovary. Dehydroepiandrosterone (DHEA) can be converted to testosterone; androstenedione; estradiol; and estrone. Most of DHEA is sulfated (dehydroepiandrosterone sulfate) before secretion.
In the United States, DHEA or DHEAS have been advertised with claims that they may be beneficial for a wide variety of ailments. DHEA and DHEAS are readily available in the United States, where they are marketed as over-the-counter dietary supplements. In November 2016, DHEA was approved (as Intrarosa) to treat women experiencing moderate to severe pain during sexual intercourse (dyspareunia), a symptom of vulvar and vaginal atrophy (VVA), due to menopause.
In Canada, a prescription is required to buy DHEA.
Fitur visualisasi ini dikembangkan menggunakan pendekatan Graph Theory untuk memetakan hubungan polifarmasi dan molekuler. Entitas (Obat, Target, Gen) direpresentasikan sebagai Simpul (Nodes), sedangkan hubungan biologisnya sebagai Sisi (Edges).
drugbank-id dan name pada skema XML DrugBank.targets/target yang memuat polipeptida sasaran.gene-name dan varian snp-effects.Tata letak grafik menggunakan algoritma Force-Directed Graph (Barnes-Hut). Model fisika ini menerapkan gaya tolak-menolak antar simpul (Gravitasi: -3000) agar tidak tumpang tindih, serta gaya pegas (Spring: 0.04) pada garis penghubung untuk fleksibilitas interaksi.
| Testosterone | The serum concentration of Testosterone can be increased when it is combined with Prasterone. |
| Testosterone propionate | The serum concentration of Testosterone propionate can be increased when it is combined with Prasterone. |
| 1-Testosterone | The serum concentration of 1-Testosterone can be increased when it is combined with Prasterone. |
| 4-Hydroxytestosterone | The serum concentration of 4-Hydroxytestosterone can be increased when it is combined with Prasterone. |
| Dehydrochloromethyltestosterone | The serum concentration of Dehydrochloromethyltestosterone can be increased when it is combined with Prasterone. |
| Boldenone | The serum concentration of Boldenone can be increased when it is combined with Prasterone. |
| 18-methyl-19-nortestosterone | The serum concentration of 18-methyl-19-nortestosterone can be increased when it is combined with Prasterone. |
| Calusterone | The serum concentration of Calusterone can be increased when it is combined with Prasterone. |
| Formebolone | The serum concentration of Formebolone can be increased when it is combined with Prasterone. |
| Methyl-1-testosterone | The serum concentration of Methyl-1-testosterone can be increased when it is combined with Prasterone. |
| 5beta-dihydrotestosterone | The serum concentration of 5beta-dihydrotestosterone can be increased when it is combined with Prasterone. |
| Testosterone succinate | The serum concentration of Testosterone succinate can be increased when it is combined with Prasterone. |
| Mibolerone | The serum concentration of Mibolerone can be increased when it is combined with Prasterone. |
| Testosterone cypionate | The serum concentration of Testosterone cypionate can be increased when it is combined with Prasterone. |
| Testosterone enanthate | The serum concentration of Testosterone enanthate can be increased when it is combined with Prasterone. |
| Testosterone undecanoate | The serum concentration of Testosterone undecanoate can be increased when it is combined with Prasterone. |
| Testosterone enantate benzilic acid hydrazone | The serum concentration of Testosterone enantate benzilic acid hydrazone can be increased when it is combined with Prasterone. |
| Stanolone acetate | The serum concentration of Stanolone acetate can be increased when it is combined with Prasterone. |
| Trestolone acetate | The serum concentration of Trestolone acetate can be increased when it is combined with Prasterone. |
| (1,2,6,7-3H)Testosterone | The serum concentration of (1,2,6,7-3H)Testosterone can be increased when it is combined with Prasterone. |
| Drostanolone propionate | The serum concentration of Drostanolone propionate can be increased when it is combined with Prasterone. |
| Stanolone | The serum concentration of Stanolone can be increased when it is combined with Prasterone. |
| Diethylstilbestrol | The risk or severity of adverse effects can be increased when Prasterone is combined with Diethylstilbestrol. |
| Chlorotrianisene | The risk or severity of adverse effects can be increased when Prasterone is combined with Chlorotrianisene. |
| Conjugated estrogens | The risk or severity of adverse effects can be increased when Prasterone is combined with Conjugated estrogens. |
| Estrone | The risk or severity of adverse effects can be increased when Prasterone is combined with Estrone. |
| Estradiol | The risk or severity of adverse effects can be increased when Prasterone is combined with Estradiol. |
| Dienestrol | The risk or severity of adverse effects can be increased when Prasterone is combined with Dienestrol. |
| Ethinylestradiol | The risk or severity of adverse effects can be increased when Prasterone is combined with Ethinylestradiol. |
| Mestranol | The risk or severity of adverse effects can be increased when Prasterone is combined with Mestranol. |
| Estriol | The risk or severity of adverse effects can be increased when Prasterone is combined with Estriol. |
| Estrone sulfate | The risk or severity of adverse effects can be increased when Prasterone is combined with Estrone sulfate. |
| Quinestrol | The risk or severity of adverse effects can be increased when Prasterone is combined with Quinestrol. |
| Hexestrol | The risk or severity of adverse effects can be increased when Prasterone is combined with Hexestrol. |
| Tibolone | The risk or severity of adverse effects can be increased when Prasterone is combined with Tibolone. |
| Synthetic Conjugated Estrogens, A | The risk or severity of adverse effects can be increased when Prasterone is combined with Synthetic Conjugated Estrogens, A. |
| Synthetic Conjugated Estrogens, B | The risk or severity of adverse effects can be increased when Prasterone is combined with Synthetic Conjugated Estrogens, B. |
| Polyestradiol phosphate | The risk or severity of adverse effects can be increased when Prasterone is combined with Polyestradiol phosphate. |
| Esterified estrogens | The risk or severity of adverse effects can be increased when Prasterone is combined with Esterified estrogens. |
| Zeranol | The risk or severity of adverse effects can be increased when Prasterone is combined with Zeranol. |
| Equol | The risk or severity of adverse effects can be increased when Prasterone is combined with Equol. |
| Promestriene | The risk or severity of adverse effects can be increased when Prasterone is combined with Promestriene. |
| Methallenestril | The risk or severity of adverse effects can be increased when Prasterone is combined with Methallenestril. |
| Epimestrol | The risk or severity of adverse effects can be increased when Prasterone is combined with Epimestrol. |
| Moxestrol | The risk or severity of adverse effects can be increased when Prasterone is combined with Moxestrol. |
| Estradiol acetate | The risk or severity of adverse effects can be increased when Prasterone is combined with Estradiol acetate. |
| Estradiol benzoate | The risk or severity of adverse effects can be increased when Prasterone is combined with Estradiol benzoate. |
| Estradiol cypionate | The risk or severity of adverse effects can be increased when Prasterone is combined with Estradiol cypionate. |
| Estradiol valerate | The risk or severity of adverse effects can be increased when Prasterone is combined with Estradiol valerate. |
| Biochanin A | The risk or severity of adverse effects can be increased when Prasterone is combined with Biochanin A. |
| Formononetin | The risk or severity of adverse effects can be increased when Prasterone is combined with Formononetin. |
| Estetrol | The risk or severity of adverse effects can be increased when Prasterone is combined with Estetrol. |
| Lasmiditan | The serum concentration of Prasterone can be increased when it is combined with Lasmiditan. |
| Cenobamate | The serum concentration of Prasterone can be decreased when it is combined with Cenobamate. |
| Tafamidis | The serum concentration of Prasterone can be increased when it is combined with Tafamidis. |
| Ritonavir | The serum concentration of Prasterone can be increased when it is combined with Ritonavir. |
| Haloperidol | The serum concentration of Haloperidol can be increased when it is combined with Prasterone. |
| Tucatinib | The metabolism of Tucatinib can be decreased when combined with Prasterone. |
| Abametapir | The serum concentration of Prasterone can be increased when it is combined with Abametapir. |
| Satralizumab | The serum concentration of Prasterone can be decreased when it is combined with Satralizumab. |
| Filgotinib | The serum concentration of Prasterone can be increased when it is combined with Filgotinib. |
| Febuxostat | The excretion of Prasterone can be decreased when combined with Febuxostat. |
| Sotorasib | The serum concentration of Prasterone can be decreased when it is combined with Sotorasib. |
| Lemborexant | The serum concentration of Lemborexant can be increased when it is combined with Prasterone. |
| Hydroxyzine | The metabolism of Hydroxyzine can be decreased when combined with Prasterone. |
| Clindamycin | The metabolism of Clindamycin can be decreased when combined with Prasterone. |
| Capmatinib | The serum concentration of Capmatinib can be increased when it is combined with Prasterone. |
| Selpercatinib | The serum concentration of Selpercatinib can be increased when it is combined with Prasterone. |
| Somatrogon | The metabolism of Prasterone can be increased when combined with Somatrogon. |
| Roxadustat | The serum concentration of Prasterone can be increased when it is combined with Roxadustat. |
| Pacritinib | The serum concentration of Prasterone can be increased when it is combined with Pacritinib. |
| Oteseconazole | The serum concentration of Prasterone can be increased when it is combined with Oteseconazole. |
| Mavacamten | The serum concentration of Prasterone can be decreased when it is combined with Mavacamten. |
| Viloxazine | The metabolism of Prasterone can be decreased when combined with Viloxazine. |
| Ivosidenib | The metabolism of Prasterone can be increased when combined with Ivosidenib. |
| Dabrafenib | The serum concentration of Prasterone can be decreased when it is combined with Dabrafenib. |
| Stiripentol | The metabolism of Prasterone can be decreased when combined with Stiripentol. |
| Enzalutamide | The serum concentration of Prasterone can be decreased when it is combined with Enzalutamide. |
| Telotristat ethyl | The serum concentration of Prasterone can be decreased when it is combined with Telotristat ethyl. |
| Rilpivirine | The serum concentration of Rilpivirine can be increased when it is combined with Prasterone. |
| Avanafil | The serum concentration of Avanafil can be increased when it is combined with Prasterone. |
| Pretomanid | The serum concentration of Prasterone can be increased when it is combined with Pretomanid. |
| Elacestrant | The serum concentration of Prasterone can be increased when it is combined with Elacestrant. |
| Omaveloxolone | The serum concentration of Prasterone can be decreased when it is combined with Omaveloxolone. |
| Apalutamide | The serum concentration of Prasterone can be decreased when it is combined with Apalutamide. |
| Trofinetide | The serum concentration of Prasterone can be increased when it is combined with Trofinetide. |
| Leniolisib | The excretion of Prasterone can be decreased when combined with Leniolisib. |
| Ivacaftor | The serum concentration of Prasterone can be increased when it is combined with Ivacaftor. |
| Erythromycin | The serum concentration of Prasterone can be increased when it is combined with Erythromycin. |
| Elexacaftor | The serum concentration of Prasterone can be increased when it is combined with Elexacaftor. |
| Epcoritamab | The serum concentration of Prasterone can be increased when it is combined with Epcoritamab. |
| Vadadustat | The serum concentration of Prasterone can be increased when it is combined with Vadadustat. |
| Fedratinib | The serum concentration of Prasterone can be increased when it is combined with Fedratinib. |
| Glofitamab | The serum concentration of Prasterone can be increased when it is combined with Glofitamab. |
| Ritlecitinib | The serum concentration of Prasterone can be increased when it is combined with Ritlecitinib. |
| Momelotinib | The serum concentration of Prasterone can be increased when it is combined with Momelotinib. |
| Bosutinib | The serum concentration of Bosutinib can be increased when it is combined with Prasterone. |
| Encorafenib | The serum concentration of Prasterone can be increased when it is combined with Encorafenib. |
| Danicopan | The serum concentration of Prasterone can be increased when it is combined with Danicopan. |
| Ceftobiprole medocaril | The serum concentration of Prasterone can be increased when it is combined with Ceftobiprole medocaril. |