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2279

Total database: 17430
Struktur (SMILES)
866 (38.0%)
Target
1100 (48.3%)
Genomik
31 (1.4%)
Referensi
2279 (100.0%)

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Hasil Pencarian (2279)

Halaman 1 / 46
small molecule

Deskripsi belum tersedia.

Target Protein:
Alpha-mannosidase 2
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small molecule

Deskripsi belum tersedia.

Target Protein:
11-beta-hydroxysteroid dehydrogenase 1
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small molecule

Deskripsi belum tersedia.

Target Protein:
Estrogen receptor
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(4R)-limonene DB08921
small molecule | CAS: 5989-27-5

Limonene is common in cosmetic products. As the main odor constituent of citrus (plant family Rutaceae), D-limonene is used in food manufacturing and some medicines, e.g. as a flavoring to mask the bitter taste of alkaloids, and as a fragrant in perfumery.

Kategori:
Cyclohexane MonoterpenesCyclohexanesCyclohexenes +3
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small molecule

Deskripsi belum tersedia.

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small molecule | CAS: 611-71-2

Deskripsi belum tersedia.

Target Protein:
Benzoylformate decarboxylaseMandelate racemase
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small molecule | CAS: 71807-09-5

Deskripsi belum tersedia.

Target Protein:
Lactase-like protein
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small molecule | CAS: 17199-29-0

Deskripsi belum tersedia.

Target Protein:
Mandelate racemase
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Genetik -
small molecule | CAS: 28549-12-4

Deskripsi belum tersedia.

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small molecule

Deskripsi belum tersedia.

Target Protein:
Aldo-keto reductase family 1 member B1
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Genetik -
biotech | CAS: 114471-18-0

Deskripsi belum tersedia.

Kategori:
Amino Acids, Peptides, and ProteinsCardiovascular AgentsHormones +8
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small molecule

Deskripsi belum tersedia.

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small molecule

Deskripsi belum tersedia.

Target Protein:
Fructose-bisphosphate aldolase A
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small molecule

Deskripsi belum tersedia.

Kategori:
Bridged-Ring CompoundsCycloparaffinsHeme Oxygenase-1, antagonists & inhibitors
Target Protein:
Heme oxygenase 1
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small molecule

Deskripsi belum tersedia.

Target Protein:
Cation-dependent mannose-6-phosphate receptor
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small molecule | CAS: 84444-90-6

An alpha-glucosidase inhibitor with antiviral action. Derivatives of deoxynojirimycin may have anti-HIV activity. [PubChem]

Kategori:
AlkaloidsAnti-Infective AgentsCarbohydrates +5
Target Protein:
Alpha-mannosidase 2
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105AD7 DB05113
small molecule

105AD7 is a human monoclonal antibody that mimics the complement regulatory protein, CD55, overexpressed by many solid tumours including osteosarcoma. 105AD7 induced antitumour inflammatory responses in metastatic colorectal cancer patients. 105AD7 may be a s…

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small molecule | CAS: 308123-60-6

18-methoxycoronaridine is under investigation in clinical trial NCT03084952 (Phase 2 Trial to Evaluate 18-Methoxycoronaridine Efficacy, Safety and Tolerability in Cutaneous Leishmaniasis Patients).

Kategori:
AlkaloidsHeterocyclic Compounds, Fused-RingIndole Alkaloids +4
Target Protein:
Neuronal acetylcholine receptor subunit alpha-2Neuronal acetylcholine receptor subunit alpha-3
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1D09C3 DB05121
biotech | CAS: 791073-97-7

1D09C3, a monoclonal antibody against lymphoid cancers, is an anti-MHC (major histocompatibility complex) class II monoclonal antibody. The antibody was isolated in collaboration with MorphoSys from its HuCAL(R) library of human antibodies. 1D09C3 binds to ce…

Target Protein:
HLA-DR
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small molecule | CAS: 2147-59-3

Deskripsi belum tersedia.

Kategori:
CarbohydratesDeoxyribonucleotidesGlycosides +5
Target Protein:
dTDP-4-dehydrorhamnose reductaseGlucose-1-phosphate thymidylyltransferase
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small molecule | CAS: 69123-94-0

2'-fluoro-5-ethylarabinosyluracil (FAU) has been used in trials studying the treatment of Small Intestine Lymphoma, Stage IV Mantle Cell Lymphoma, Waldenström Macroglobulinemia, Splenic Marginal Zone Lymphoma, and Recurrent Mantle Cell Lymphoma, among others.

Kategori:
Anti-Infective AgentsAntiviral AgentsArabinonucleosides +6
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small molecule | CAS: 51-28-5

A toxic dye, chemically related to trinitrophenol (picric acid), used in biochemical studies of oxidative processes where it uncouples oxidative phosphorylation. It is also used as a metabolic stimulant. (Stedman, 26th ed)

Kategori:
Benzene DerivativesColoring AgentsCompounds used in a research, industrial, or household setting +6
Target Protein:
Pentaerythritol tetranitrate reductase
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small molecule

Deskripsi belum tersedia.

Target Protein:
Beta-mannosidase
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Genetik -
small molecule

Deskripsi belum tersedia.

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Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
11-beta-hydroxysteroid dehydrogenase 1
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small molecule | CAS: 62182-14-3

Deskripsi belum tersedia.

Target Protein:
Mannan endo-1,4-beta-mannosidase
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Genetik -
small molecule | CAS: 55449-80-4

Deskripsi belum tersedia.

Target Protein:
Mannan endo-1,4-beta-mannosidase
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Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Alpha-mannosidase 2
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2G7 DB18589
biotech

2G7 is an anti-TGF-beta monoclonal antibody developed by Genentech.

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small molecule

Deskripsi belum tersedia.

Target Protein:
Ferrichrome-iron receptor
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Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
AlgQ1AlgQ2
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Genetik -
small molecule | CAS: 2141-17-5

4-Hydroxytestosterone is testosterone substituted with a hydroxy group on the fourth carbon atom. It is an anabolic steroid with no therapeutic indications, which is prohibited from use in sports by the World Anti-Doping Agency. Formestane (Lentaron) acts …

Kategori:
AndrostanesAndrostenesAndrostenols +4
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KlirensClearance is via th…
Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Alpha-amylase 2B
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small molecule

Deskripsi belum tersedia.

Target Protein:
Xanthan lyase
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4D-310 DB18323
biotech

4D-310 is a adeno-Associated Virus Serotype 2 capsid variant (4D-C102) carrying a transgene encoding a codon-optimized human alpha-galactosidase A gene

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small molecule | CAS: 4021-34-5

5-methoxy-N,N-diisopropyltryptamine (5-MeO-DIPT) is a tryptamine derivative and shares many similarities with schedule I tryptamine hallucinogens such as alpha-ethyltryptamine, N,N-dimethyltryptamine, N,N-diethyltryptamine, bufotenine, psilocybin and psilocin…

Kategori:
AlkaloidsAminesBiogenic Amines +8
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small molecule

Deskripsi belum tersedia.

Target Protein:
Alpha-mannosidase 2
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A166 DB17413
biotech

A166 is an antibody-drug conjugate composed of a novel cytotoxic drug (Duo-5, anti-microtubule agent) site-specifically conjugated to an anti-HER2 antibody (trastuzumab) via a stable protease-cleavable valine citrulline linker.

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AAV-AIPL DB17857
biotech

AAV-AIPL is an adenovirus-associated viral vector serotype 8 containing the human _AIPL1_ gene. Developed by MeiraGTx, it is being investigated for the treatment of inherited retinal dystrophy due to defects in _AIPL1_ gene.

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AAV-CNGB3 DB18344
biotech

AAV-CNGB3 is an adenovirus associated viral vector serotype 8 containing the human CNGB3 gene.

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AAV-RPE65 DB18343
biotech

AAV-RPE65 is an adenovirus associated viral vector serotype 5 containing the human RPE65 gene

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biotech

Deskripsi belum tersedia.

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AAV9/MFSD8 DB18616
biotech

AAV9/MFSD8 is a gene therapy developed by Neurogene Inc. It is an adeno-associated virus serotype 9 (AAV9) vector with an engineered transgene encoding the human CLN7/MFSD8 gene for expression of active human major facilitator superfamily domain containing 8.…

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Abaloparatide Approved DB05084
biotech | CAS: 247062-33-5

Abaloparatide is an N-terminal analog of parathyroid hormone-related protein (PTHrP) [A256778] and an agonist at the parathyroid hormone type 1 (PTH1) receptor.[L740] It is a synthetic 34 amino acid peptide with 41% homology to human parathyroid hormone 1-34 …

Kategori:
Amino Acids, Peptides, and ProteinsAnalogs/DerivativesBiological Factors +13
Target Protein:
Parathyroid hormone/parathyroid hormone-related peptide receptor
Waktu ParuhThe mean half-life …
Vol. DistribusiThe volume of distr…
KlirensThe mean apparent t…
Genetik -
Abametapir Approved DB11932
small molecule | CAS: 1762-34-1

Abametapir is a novel pediculicidal metalloproteinase inhibitor used to treat infestations of head lice.[L15153] The life cycle of head lice (_Pediculus capitis_) is approximately 30 days, seven to twelve of which are spent as eggs laid on hair shafts near th…

Kategori:
Antiparasitic Products, Insecticides and RepellentsCytochrome P-450 CYP1A2 InhibitorsCytochrome P-450 CYP1A2 Inhibitors (strength unknown) +13
Waktu ParuhThe elimination hal…
Vol. DistribusiData regarding the …
KlirensThe clearance and e…
Genetik -
Abatacept Approved DB01281
biotech | CAS: 332348-12-6

Abatacept is a soluble fusion protein, which links the extracellular domain of human cytotoxic T-lymphocyte-associated antigen 4 (CTLA-4) to the modified Fc (hinge, CH2, and CH3 domains) portion of human immunoglobulin G1 (IgG1).[L20504,L42715] Structurally, …

Kategori:
Agents reducing cytokine levelsAmino Acids, Peptides, and ProteinsAntibodies +18
Target Protein:
T-lymphocyte activation antigen CD80T-lymphocyte activation antigen CD86Cytotoxic T-lymphocyte protein 4
Waktu Paruh16.7 (12-23) days i…
Vol. Distribusi* 0.07 L/kg [RA Pat…
Klirens* 0.23 mL/h/kg [Hea…
Genetik -
ABBV-011 DB18622
biotech

ABBV-011 is an antibody-drug conjugate of humanized, cysteine-engineered IgG1 monoclonal antibody targeting seizure-related 6 homolog conjugated to N-acetyl-gamma-calicheamicin.

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Abciximab Approved DB00054
biotech | CAS: 143653-53-6

Abciximab is a Fab fragment of the chimeric human-murine monoclonal antibody 7E3. Abciximab binds to the glycoprotein (GP) IIb/IIIa receptor of human platelets and inhibits platelet aggregation by preventing the binding of fibrinogen, von Willebrand factor, a…

Kategori:
Amino Acids, Peptides, and ProteinsAntibodiesAntibodies, Monoclonal +18
Target Protein:
Integrin beta-3Integrin alpha-IIbLow affinity immunoglobulin gamma Fc region receptor II-a +2
Waktu ParuhFollowing intraveno…
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Abiprubart DB19333
biotech | CAS: 2765071-95-0

Abiprubart is being evaluated for its efficacy and safety in participants with Sjögren's Disease in clinical trial NCT06531395

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