Symptoms of mazindol overdose may be associated with restlessness, tremor, rapid breathing, confusion, hallucinations, panic, aggressiveness, nausea, vomiting, diarrhea, an irregular heartbeat, and seizures.
Mazindol is a tricyclic anorexigenic agent that is unrelated to and less toxic than amphetamine, but with some similar side effects. It inhibits uptake of catecholamines and blocks the binding of cocaine to the dopamine uptake transporter. Mazindol is only approved in the United States for the treatment of Duchenne muscular dystrophy, and is not marketed or available in the United States for use in the treatment of obesity.
Fitur visualisasi ini dikembangkan menggunakan pendekatan Graph Theory untuk memetakan hubungan polifarmasi dan molekuler. Entitas (Obat, Target, Gen) direpresentasikan sebagai Simpul (Nodes), sedangkan hubungan biologisnya sebagai Sisi (Edges).
drugbank-id dan name pada skema XML DrugBank.targets/target yang memuat polipeptida sasaran.gene-name dan varian snp-effects.Tata letak grafik menggunakan algoritma Force-Directed Graph (Barnes-Hut). Model fisika ini menerapkan gaya tolak-menolak antar simpul (Gravitasi: -3000) agar tidak tumpang tindih, serta gaya pegas (Spring: 0.04) pada garis penghubung untuk fleksibilitas interaksi.
| Buprenorphine | Mazindol may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine. |
| Doxylamine | Doxylamine may increase the central nervous system depressant (CNS depressant) activities of Mazindol. |
| Dronabinol | Dronabinol may increase the central nervous system depressant (CNS depressant) activities of Mazindol. |
| Droperidol | Droperidol may increase the central nervous system depressant (CNS depressant) activities of Mazindol. |
| Hydrocodone | Mazindol may increase the central nervous system depressant (CNS depressant) activities of Hydrocodone. |
| Hydroxyzine | Hydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Mazindol. |
| Magnesium sulfate | The therapeutic efficacy of Mazindol can be increased when used in combination with Magnesium sulfate. |
| Methotrimeprazine | Mazindol may increase the central nervous system depressant (CNS depressant) activities of Methotrimeprazine. |
| Metyrosine | Mazindol may increase the sedative activities of Metyrosine. |
| Minocycline | Minocycline may increase the central nervous system depressant (CNS depressant) activities of Mazindol. |
| Nabilone | Nabilone may increase the central nervous system depressant (CNS depressant) activities of Mazindol. |
| Orphenadrine | Mazindol may increase the central nervous system depressant (CNS depressant) activities of Orphenadrine. |
| Paraldehyde | Mazindol may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde. |
| Perampanel | Perampanel may increase the central nervous system depressant (CNS depressant) activities of Mazindol. |
| Pramipexole | Mazindol may increase the sedative activities of Pramipexole. |
| Ropinirole | Mazindol may increase the sedative activities of Ropinirole. |
| Rotigotine | Mazindol may increase the sedative activities of Rotigotine. |
| Rufinamide | The risk or severity of adverse effects can be increased when Rufinamide is combined with Mazindol. |
| Sodium oxybate | Mazindol may increase the central nervous system depressant (CNS depressant) activities of Sodium oxybate. |
| Suvorexant | Mazindol may increase the central nervous system depressant (CNS depressant) activities of Suvorexant. |
| Tapentadol | Tapentadol may increase the central nervous system depressant (CNS depressant) activities of Mazindol. |
| Thalidomide | Mazindol may increase the central nervous system depressant (CNS depressant) activities of Thalidomide. |
| Zolpidem | Mazindol may increase the central nervous system depressant (CNS depressant) activities of Zolpidem. |
| Methadone | The risk or severity of adverse effects can be increased when Methadone is combined with Mazindol. |
| Linezolid | The risk or severity of serotonin syndrome can be increased when Linezolid is combined with Mazindol. |
| Dicoumarol | The risk or severity of adverse effects can be increased when Mazindol is combined with Dicoumarol. |
| Phenindione | The risk or severity of adverse effects can be increased when Mazindol is combined with Phenindione. |
| Warfarin | The risk or severity of adverse effects can be increased when Mazindol is combined with Warfarin. |
| Phenprocoumon | The risk or severity of adverse effects can be increased when Mazindol is combined with Phenprocoumon. |
| Acenocoumarol | The risk or severity of adverse effects can be increased when Mazindol is combined with Acenocoumarol. |
| 4-hydroxycoumarin | The risk or severity of adverse effects can be increased when Mazindol is combined with 4-hydroxycoumarin. |
| Coumarin | The risk or severity of adverse effects can be increased when Mazindol is combined with Coumarin. |
| (R)-warfarin | The risk or severity of adverse effects can be increased when Mazindol is combined with (R)-warfarin. |
| Ethyl biscoumacetate | The risk or severity of adverse effects can be increased when Mazindol is combined with Ethyl biscoumacetate. |
| Fluindione | The risk or severity of adverse effects can be increased when Mazindol is combined with Fluindione. |
| Clorindione | The risk or severity of adverse effects can be increased when Mazindol is combined with Clorindione. |
| Diphenadione | The risk or severity of adverse effects can be increased when Mazindol is combined with Diphenadione. |
| Tioclomarol | The risk or severity of adverse effects can be increased when Mazindol is combined with Tioclomarol. |
| (S)-Warfarin | The risk or severity of adverse effects can be increased when Mazindol is combined with (S)-Warfarin. |
| Tedizolid phosphate | The risk or severity of serotonin syndrome can be increased when Tedizolid phosphate is combined with Mazindol. |
| Mirtazapine | Mazindol may increase the serotonergic activities of Mirtazapine. |
| Ethanol | Mazindol may increase the central nervous system depressant (CNS depressant) activities of Ethanol. |
| Azelastine | Mazindol may increase the central nervous system depressant (CNS depressant) activities of Azelastine. |
| Brimonidine | Brimonidine may increase the central nervous system depressant (CNS depressant) activities of Mazindol. |
| Fluvoxamine | The risk or severity of adverse effects can be increased when Mazindol is combined with Fluvoxamine. |
| Citalopram | The risk or severity of adverse effects can be increased when Mazindol is combined with Citalopram. |
| Duloxetine | The risk or severity of adverse effects can be increased when Mazindol is combined with Duloxetine. |
| Paroxetine | The risk or severity of adverse effects can be increased when Mazindol is combined with Paroxetine. |
| Sertraline | The risk or severity of adverse effects can be increased when Mazindol is combined with Sertraline. |
| Sibutramine | The risk or severity of adverse effects can be increased when Mazindol is combined with Sibutramine. |
| Nefazodone | The risk or severity of adverse effects can be increased when Mazindol is combined with Nefazodone. |
| Zimelidine | The risk or severity of adverse effects can be increased when Mazindol is combined with Zimelidine. |
| Dapoxetine | The risk or severity of adverse effects can be increased when Mazindol is combined with Dapoxetine. |
| Milnacipran | The risk or severity of adverse effects can be increased when Mazindol is combined with Milnacipran. |
| Desvenlafaxine | The risk or severity of serotonin syndrome can be increased when Desvenlafaxine is combined with Mazindol. |
| Seproxetine | The risk or severity of adverse effects can be increased when Mazindol is combined with Seproxetine. |
| Levomilnacipran | The risk or severity of serotonin syndrome can be increased when Mazindol is combined with Levomilnacipran. |
| Indalpine | The risk or severity of adverse effects can be increased when Mazindol is combined with Indalpine. |
| Ritanserin | The risk or severity of adverse effects can be increased when Mazindol is combined with Ritanserin. |
| Alaproclate | The risk or severity of adverse effects can be increased when Mazindol is combined with Alaproclate. |
| Methylene blue | Mazindol may increase the serotonergic activities of Methylene blue. |
| Iobenguane | Mazindol can cause a decrease in the absorption of Iobenguane resulting in a reduced serum concentration and potentially a decrease in efficacy. |
| Zopiclone | The risk or severity of adverse effects can be increased when Mazindol is combined with Zopiclone. |
| Reserpine | The risk or severity of adverse effects can be increased when Mazindol is combined with Reserpine. |
| Clozapine | The risk or severity of adverse effects can be increased when Mazindol is combined with Clozapine. |
| Thiethylperazine | The risk or severity of adverse effects can be increased when Mazindol is combined with Thiethylperazine. |
| Sulpiride | The risk or severity of adverse effects can be increased when Mazindol is combined with Sulpiride. |
| Remoxipride | The risk or severity of adverse effects can be increased when Mazindol is combined with Remoxipride. |
| Prochlorperazine | The risk or severity of adverse effects can be increased when Mazindol is combined with Prochlorperazine. |
| Triflupromazine | The risk or severity of adverse effects can be increased when Mazindol is combined with Triflupromazine. |
| Fluphenazine | The risk or severity of adverse effects can be increased when Mazindol is combined with Fluphenazine. |
| Moricizine | The risk or severity of adverse effects can be increased when Mazindol is combined with Moricizine. |
| Trifluoperazine | The risk or severity of adverse effects can be increased when Mazindol is combined with Trifluoperazine. |
| Perphenazine | The risk or severity of adverse effects can be increased when Mazindol is combined with Perphenazine. |
| Mesoridazine | The risk or severity of adverse effects can be increased when Mazindol is combined with Mesoridazine. |
| Acetophenazine | The risk or severity of adverse effects can be increased when Mazindol is combined with Acetophenazine. |
| Pimozide | The risk or severity of adverse effects can be increased when Mazindol is combined with Pimozide. |
| Chlorprothixene | The risk or severity of adverse effects can be increased when Mazindol is combined with Chlorprothixene. |
| Alimemazine | The risk or severity of adverse effects can be increased when Mazindol is combined with Alimemazine. |
| Periciazine | The risk or severity of adverse effects can be increased when Mazindol is combined with Periciazine. |
| Acepromazine | The risk or severity of adverse effects can be increased when Mazindol is combined with Acepromazine. |
| Aceprometazine | The risk or severity of adverse effects can be increased when Mazindol is combined with Aceprometazine. |
| Molindone | The risk or severity of adverse effects can be increased when Mazindol is combined with Molindone. |
| Pipotiazine | The risk or severity of adverse effects can be increased when Mazindol is combined with Pipotiazine. |
| Thioproperazine | The risk or severity of adverse effects can be increased when Mazindol is combined with Thioproperazine. |
| Thiothixene | The risk or severity of adverse effects can be increased when Mazindol is combined with Thiothixene. |
| Osanetant | The risk or severity of adverse effects can be increased when Mazindol is combined with Osanetant. |
| Bifeprunox | The risk or severity of adverse effects can be increased when Mazindol is combined with Bifeprunox. |
| BL-1020 | The risk or severity of adverse effects can be increased when Mazindol is combined with BL-1020. |
| Lumateperone | The risk or severity of adverse effects can be increased when Mazindol is combined with Lumateperone. |
| Amisulpride | The risk or severity of adverse effects can be increased when Mazindol is combined with Amisulpride. |
| Perospirone | The risk or severity of adverse effects can be increased when Mazindol is combined with Perospirone. |
| Amperozide | The risk or severity of adverse effects can be increased when Mazindol is combined with Amperozide. |
| Cyamemazine | The risk or severity of adverse effects can be increased when Mazindol is combined with Cyamemazine. |
| Melperone | The risk or severity of adverse effects can be increased when Mazindol is combined with Melperone. |
| Brilaroxazine | The risk or severity of adverse effects can be increased when Mazindol is combined with Brilaroxazine. |
| Azaperone | The risk or severity of adverse effects can be increased when Mazindol is combined with Azaperone. |
| Propiopromazine | The risk or severity of adverse effects can be increased when Mazindol is combined with Propiopromazine. |
| Tetrahydropalmatine | The risk or severity of adverse effects can be increased when Mazindol is combined with Tetrahydropalmatine. |
| Ecopipam | The risk or severity of adverse effects can be increased when Mazindol is combined with Ecopipam. |