Peringatan Keamanan

There are no data regarding overdosage of chikungunya virus vaccine.

Chikungunya vaccine (live, attenuated)

DB18701

biotech approved

Deskripsi

Chikungunya virus (CHIKV) is a member of the Alphavirus genus that was first identified in Tanzania in 1952.A262051 It is spread primarily by the bite of infected mosquitos of the Aedes genus. Infection with CHIKV causes chikungunya fever, an illness characterized by acute fever and severe, persistent arthralgia.A262051 Prior to 2013, chikungunya virus cases and outbreaks had been identified in countries in Africa, Asia, Europe, and the Indian and Pacific Oceans. In late 2013, the first cases were identified in the Caribbean, and it has since spread to most of the Americas.L48786 There are no approved treatments for active chikungunya virus infection.L48731

Chikungunya vaccine (live, attenuated) - marketed under the name Ixchiq - was approved by the FDA in November 2023, becoming the first and only vaccine indicated for the prevention of disease caused by chikungunya virus.L48726 It is approved for use in patients 18 years of age and older who are at high-risk of exposure to chikungunya virus.

Struktur Molekul 2D

Struktur tidak tersedia

Peta Jejaring Molekuler
Legenda: ObatTargetGenEnzim(Panah → menunjukkan arah efek / relasi)TransporterCarrier

Profil Farmakokinetik

Waktu Paruh (Half-Life) There is limited pharmacokinetic information on chikungunya virus vaccine.
Volume Distribusi There is limited pharmacokinetic information on chikungunya virus vaccine.
Klirens (Clearance) There is limited pharmacokinetic information on chikungunya virus vaccine.

Absorpsi

There is limited pharmacokinetic information on chikungunya virus vaccine.

Metabolisme

As with other live attenuated vaccines, chikungunya virus vaccine is likely to undergo nonspecific cellular degradation.

Rute Eliminasi

Although there is limited information on the main route of elimination of chikungunya virus vaccine, virus was detected in the urine of one participant on day 8 following intramuscular injection.L48716

Interaksi Obat

422 Data
Etanercept The risk or severity of infection can be increased when Chikungunya vaccine (live, attenuated) is combined with Etanercept.
Peginterferon alfa-2a The risk or severity of infection can be increased when Chikungunya vaccine (live, attenuated) is combined with Peginterferon alfa-2a.
Interferon alfa-n1 The risk or severity of infection can be increased when Chikungunya vaccine (live, attenuated) is combined with Interferon alfa-n1.
Interferon alfa-n3 The risk or severity of infection can be increased when Chikungunya vaccine (live, attenuated) is combined with Interferon alfa-n3.
Peginterferon alfa-2b The risk or severity of infection can be increased when Chikungunya vaccine (live, attenuated) is combined with Peginterferon alfa-2b.
Anakinra The risk or severity of infection can be increased when Chikungunya vaccine (live, attenuated) is combined with Anakinra.
Interferon gamma-1b The risk or severity of infection can be increased when Chikungunya vaccine (live, attenuated) is combined with Interferon gamma-1b.
Interferon alfa-2a The risk or severity of infection can be increased when Chikungunya vaccine (live, attenuated) is combined with Interferon alfa-2a.
Aldesleukin The risk or severity of infection can be increased when Chikungunya vaccine (live, attenuated) is combined with Aldesleukin.
Adalimumab The risk or severity of adverse effects can be increased when Adalimumab is combined with Chikungunya vaccine (live, attenuated).
Gemtuzumab ozogamicin The risk or severity of infection can be increased when Chikungunya vaccine (live, attenuated) is combined with Gemtuzumab ozogamicin.
Pegaspargase The risk or severity of infection can be increased when Chikungunya vaccine (live, attenuated) is combined with Pegaspargase.
Infliximab The risk or severity of infection can be increased when Chikungunya vaccine (live, attenuated) is combined with Infliximab.
Interferon beta-1b The risk or severity of infection can be increased when Chikungunya vaccine (live, attenuated) is combined with Interferon beta-1b.
Interferon alfacon-1 The risk or severity of infection can be increased when Chikungunya vaccine (live, attenuated) is combined with Interferon alfacon-1.
Trastuzumab The risk or severity of infection can be increased when Chikungunya vaccine (live, attenuated) is combined with Trastuzumab.
Rituximab The risk or severity of infection can be increased when Chikungunya vaccine (live, attenuated) is combined with Rituximab.
Basiliximab The risk or severity of infection can be increased when Chikungunya vaccine (live, attenuated) is combined with Basiliximab.
Muromonab The risk or severity of infection can be increased when Chikungunya vaccine (live, attenuated) is combined with Muromonab.
Ibritumomab tiuxetan The risk or severity of infection can be increased when Chikungunya vaccine (live, attenuated) is combined with Ibritumomab tiuxetan.
Tositumomab The risk or severity of infection can be increased when Chikungunya vaccine (live, attenuated) is combined with Tositumomab.
Alemtuzumab The risk or severity of infection can be increased when Chikungunya vaccine (live, attenuated) is combined with Alemtuzumab.
Cyclosporine The risk or severity of infection can be increased when Chikungunya vaccine (live, attenuated) is combined with Cyclosporine.
Alefacept The risk or severity of infection can be increased when Chikungunya vaccine (live, attenuated) is combined with Alefacept.
Efalizumab The risk or severity of infection can be increased when Chikungunya vaccine (live, attenuated) is combined with Efalizumab.
Antithymocyte immunoglobulin (rabbit) The risk or severity of infection can be increased when Chikungunya vaccine (live, attenuated) is combined with Antithymocyte immunoglobulin (rabbit).
Interferon alfa-2b The risk or severity of infection can be increased when Chikungunya vaccine (live, attenuated) is combined with Interferon alfa-2b.
Natalizumab The risk or severity of infection can be increased when Chikungunya vaccine (live, attenuated) is combined with Natalizumab.
Daclizumab The risk or severity of infection can be increased when Chikungunya vaccine (live, attenuated) is combined with Daclizumab.
Phenylalanine The risk or severity of infection can be increased when Chikungunya vaccine (live, attenuated) is combined with Phenylalanine.
Flunisolide The risk or severity of infection can be increased when Chikungunya vaccine (live, attenuated) is combined with Flunisolide.
Bortezomib The risk or severity of infection can be increased when Chikungunya vaccine (live, attenuated) is combined with Bortezomib.
Cladribine The risk or severity of infection can be increased when Chikungunya vaccine (live, attenuated) is combined with Cladribine.
Carmustine The risk or severity of infection can be increased when Chikungunya vaccine (live, attenuated) is combined with Carmustine.
Amsacrine The risk or severity of infection can be increased when Chikungunya vaccine (live, attenuated) is combined with Amsacrine.
Bleomycin The risk or severity of infection can be increased when Chikungunya vaccine (live, attenuated) is combined with Bleomycin.
Chlorambucil The risk or severity of infection can be increased when Chikungunya vaccine (live, attenuated) is combined with Chlorambucil.
Raltitrexed The risk or severity of infection can be increased when Chikungunya vaccine (live, attenuated) is combined with Raltitrexed.
Mitomycin The risk or severity of infection can be increased when Chikungunya vaccine (live, attenuated) is combined with Mitomycin.
Bexarotene The risk or severity of infection can be increased when Chikungunya vaccine (live, attenuated) is combined with Bexarotene.
Vindesine The risk or severity of infection can be increased when Chikungunya vaccine (live, attenuated) is combined with Vindesine.
Floxuridine The risk or severity of infection can be increased when Chikungunya vaccine (live, attenuated) is combined with Floxuridine.
Fluorometholone The risk or severity of infection can be increased when Chikungunya vaccine (live, attenuated) is combined with Fluorometholone.
Indomethacin The risk or severity of infection can be increased when Chikungunya vaccine (live, attenuated) is combined with Indomethacin.
Tioguanine The risk or severity of infection can be increased when Chikungunya vaccine (live, attenuated) is combined with Tioguanine.
Vinorelbine The risk or severity of infection can be increased when Chikungunya vaccine (live, attenuated) is combined with Vinorelbine.
Dexrazoxane The risk or severity of infection can be increased when Chikungunya vaccine (live, attenuated) is combined with Dexrazoxane.
Beclomethasone dipropionate The risk or severity of infection can be increased when Chikungunya vaccine (live, attenuated) is combined with Beclomethasone dipropionate.
Sorafenib The risk or severity of infection can be increased when Chikungunya vaccine (live, attenuated) is combined with Sorafenib.
Streptozocin The risk or severity of infection can be increased when Chikungunya vaccine (live, attenuated) is combined with Streptozocin.
Trifluridine The risk or severity of infection can be increased when Chikungunya vaccine (live, attenuated) is combined with Trifluridine.
Gemcitabine The risk or severity of infection can be increased when Chikungunya vaccine (live, attenuated) is combined with Gemcitabine.
Betamethasone The risk or severity of infection can be increased when Chikungunya vaccine (live, attenuated) is combined with Betamethasone.
Teniposide The risk or severity of infection can be increased when Chikungunya vaccine (live, attenuated) is combined with Teniposide.
Epirubicin The risk or severity of infection can be increased when Chikungunya vaccine (live, attenuated) is combined with Epirubicin.
Chloramphenicol The risk or severity of infection can be increased when Chikungunya vaccine (live, attenuated) is combined with Chloramphenicol.
Lenalidomide The risk or severity of infection can be increased when Chikungunya vaccine (live, attenuated) is combined with Lenalidomide.
Altretamine The risk or severity of infection can be increased when Chikungunya vaccine (live, attenuated) is combined with Altretamine.
Zidovudine The risk or severity of infection can be increased when Chikungunya vaccine (live, attenuated) is combined with Zidovudine.
Cisplatin The risk or severity of infection can be increased when Chikungunya vaccine (live, attenuated) is combined with Cisplatin.
Oxaliplatin The risk or severity of infection can be increased when Chikungunya vaccine (live, attenuated) is combined with Oxaliplatin.
Cyclophosphamide The risk or severity of infection can be increased when Chikungunya vaccine (live, attenuated) is combined with Cyclophosphamide.
Vincristine The risk or severity of infection can be increased when Chikungunya vaccine (live, attenuated) is combined with Vincristine.
Fluorouracil The risk or severity of infection can be increased when Chikungunya vaccine (live, attenuated) is combined with Fluorouracil.
Desoximetasone The risk or severity of infection can be increased when Chikungunya vaccine (live, attenuated) is combined with Desoximetasone.
Propylthiouracil The risk or severity of infection can be increased when Chikungunya vaccine (live, attenuated) is combined with Propylthiouracil.
Pentostatin The risk or severity of infection can be increased when Chikungunya vaccine (live, attenuated) is combined with Pentostatin.
Methotrexate The risk or severity of infection can be increased when Chikungunya vaccine (live, attenuated) is combined with Methotrexate.
Carbamazepine The risk or severity of infection can be increased when Chikungunya vaccine (live, attenuated) is combined with Carbamazepine.
Vinblastine The risk or severity of infection can be increased when Chikungunya vaccine (live, attenuated) is combined with Vinblastine.
Fluticasone propionate The risk or severity of infection can be increased when Chikungunya vaccine (live, attenuated) is combined with Fluticasone propionate.
Fluocinolone acetonide The risk or severity of infection can be increased when Chikungunya vaccine (live, attenuated) is combined with Fluocinolone acetonide.
Linezolid The risk or severity of infection can be increased when Chikungunya vaccine (live, attenuated) is combined with Linezolid.
Imatinib The risk or severity of infection can be increased when Chikungunya vaccine (live, attenuated) is combined with Imatinib.
Triamcinolone The risk or severity of infection can be increased when Chikungunya vaccine (live, attenuated) is combined with Triamcinolone.
Clofarabine The risk or severity of infection can be increased when Chikungunya vaccine (live, attenuated) is combined with Clofarabine.
Prednisone The risk or severity of infection can be increased when Chikungunya vaccine (live, attenuated) is combined with Prednisone.
Pemetrexed The risk or severity of infection can be increased when Chikungunya vaccine (live, attenuated) is combined with Pemetrexed.
Flumethasone The risk or severity of infection can be increased when Chikungunya vaccine (live, attenuated) is combined with Flumethasone.
Fludrocortisone The risk or severity of infection can be increased when Chikungunya vaccine (live, attenuated) is combined with Fludrocortisone.
Mycophenolate mofetil The risk or severity of infection can be increased when Chikungunya vaccine (live, attenuated) is combined with Mycophenolate mofetil.
Daunorubicin The risk or severity of infection can be increased when Chikungunya vaccine (live, attenuated) is combined with Daunorubicin.
Hydrocortisone The risk or severity of infection can be increased when Chikungunya vaccine (live, attenuated) is combined with Hydrocortisone.
Irinotecan The risk or severity of infection can be increased when Chikungunya vaccine (live, attenuated) is combined with Irinotecan.
Methimazole The risk or severity of infection can be increased when Chikungunya vaccine (live, attenuated) is combined with Methimazole.
Mometasone The risk or severity of infection can be increased when Chikungunya vaccine (live, attenuated) is combined with Mometasone.
Etoposide The risk or severity of infection can be increased when Chikungunya vaccine (live, attenuated) is combined with Etoposide.
Sulfasalazine The risk or severity of infection can be increased when Chikungunya vaccine (live, attenuated) is combined with Sulfasalazine.
Dacarbazine The risk or severity of infection can be increased when Chikungunya vaccine (live, attenuated) is combined with Dacarbazine.
Temozolomide The risk or severity of infection can be increased when Chikungunya vaccine (live, attenuated) is combined with Temozolomide.
Penicillamine The risk or severity of infection can be increased when Chikungunya vaccine (live, attenuated) is combined with Penicillamine.
Prednisolone The risk or severity of infection can be increased when Chikungunya vaccine (live, attenuated) is combined with Prednisolone.
Tacrolimus The risk or severity of infection can be increased when Chikungunya vaccine (live, attenuated) is combined with Tacrolimus.
Sirolimus The risk or severity of infection can be increased when Chikungunya vaccine (live, attenuated) is combined with Sirolimus.
Mechlorethamine The risk or severity of infection can be increased when Chikungunya vaccine (live, attenuated) is combined with Mechlorethamine.
Azacitidine The risk or severity of infection can be increased when Chikungunya vaccine (live, attenuated) is combined with Azacitidine.
Carboplatin The risk or severity of infection can be increased when Chikungunya vaccine (live, attenuated) is combined with Carboplatin.
Methylprednisolone The risk or severity of infection can be increased when Chikungunya vaccine (live, attenuated) is combined with Methylprednisolone.
Dactinomycin The risk or severity of infection can be increased when Chikungunya vaccine (live, attenuated) is combined with Dactinomycin.
Cytarabine The risk or severity of infection can be increased when Chikungunya vaccine (live, attenuated) is combined with Cytarabine.

Referensi & Sumber

Artikel (PubMed)
  • PMID: 28159534
    Burt FJ, Chen W, Miner JJ, Lenschow DJ, Merits A, Schnettler E, Kohl A, Rudd PA, Taylor A, Herrero LJ, Zaid A, Ng LFP, Mahalingam S: Chikungunya virus: an update on the biology and pathogenesis of this emerging pathogen. Lancet Infect Dis. 2017 Apr;17(4):e107-e117. doi: 10.1016/S1473-3099(16)30385-1. Epub 2017 Feb 1.

Contoh Produk & Brand

Produk: 2 • International brands: 1
Produk
  • Ixchiq
    Injection, powder, lyophilized, for solution • 3 [TCID_50]/0.5mL • Intramuscular • US • Approved
  • Ixchiq
    Powder, for solution • 3 Log10 TCID50 / 0.5 mL • Intramuscular • Canada • Approved
International Brands
  • Ixchiq — Valneva Austria GmbH

Sekuens Gen/Protein (FASTA)

Sekuens dimuat saat dibutuhkan agar halaman tetap ringan.
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