Plumbagin is a compound investigated for its anticancer activity. It has been found that it inactivates the Akt/NF-kB, MMP-9 and VEGF pathways.A253102
Fitur visualisasi ini dikembangkan menggunakan pendekatan Graph Theory untuk memetakan hubungan polifarmasi dan molekuler. Entitas (Obat, Target, Gen) direpresentasikan sebagai Simpul (Nodes), sedangkan hubungan biologisnya sebagai Sisi (Edges).
drugbank-id dan name pada skema XML DrugBank.targets/target yang memuat polipeptida sasaran.gene-name dan varian snp-effects.Tata letak grafik menggunakan algoritma Force-Directed Graph (Barnes-Hut). Model fisika ini menerapkan gaya tolak-menolak antar simpul (Gravitasi: -3000) agar tidak tumpang tindih, serta gaya pegas (Spring: 0.04) pada garis penghubung untuk fleksibilitas interaksi.
| Aprepitant | The serum concentration of Plumbagin can be decreased when it is combined with Aprepitant. |
| Exenatide | Exenatide can cause a decrease in the absorption of Plumbagin resulting in a reduced serum concentration and potentially a decrease in efficacy. |
| Thalidomide | Plumbagin may increase the thrombogenic activities of Thalidomide. |
| Tranexamic acid | Plumbagin may increase the thrombogenic activities of Tranexamic acid. |
| Clobazam | The serum concentration of Plumbagin can be decreased when it is combined with Clobazam. |
| Griseofulvin | The metabolism of Plumbagin can be increased when combined with Griseofulvin. |
| Flunisolide | The serum concentration of Flunisolide can be increased when it is combined with Plumbagin. |
| Fluorometholone | The serum concentration of Fluorometholone can be increased when it is combined with Plumbagin. |
| Beclomethasone dipropionate | The serum concentration of Beclomethasone dipropionate can be increased when it is combined with Plumbagin. |
| Betamethasone | The serum concentration of Betamethasone can be increased when it is combined with Plumbagin. |
| Desoximetasone | The serum concentration of Desoximetasone can be increased when it is combined with Plumbagin. |
| Fluticasone propionate | The serum concentration of Fluticasone propionate can be increased when it is combined with Plumbagin. |
| Fluocinolone acetonide | The serum concentration of Fluocinolone acetonide can be increased when it is combined with Plumbagin. |
| Triamcinolone | The serum concentration of Triamcinolone can be increased when it is combined with Plumbagin. |
| Prednisone | The serum concentration of Prednisone can be increased when it is combined with Plumbagin. |
| Flumethasone | The serum concentration of Flumethasone can be increased when it is combined with Plumbagin. |
| Fludrocortisone | The serum concentration of Fludrocortisone can be increased when it is combined with Plumbagin. |
| Hydrocortisone | The serum concentration of Hydrocortisone can be increased when it is combined with Plumbagin. |
| Mometasone | The serum concentration of Mometasone can be increased when it is combined with Plumbagin. |
| Prednisolone | The serum concentration of Prednisolone can be increased when it is combined with Plumbagin. |
| Methylprednisolone | The serum concentration of Methylprednisolone can be increased when it is combined with Plumbagin. |
| Clobetasol propionate | The serum concentration of Clobetasol propionate can be increased when it is combined with Plumbagin. |
| Fluocinonide | The serum concentration of Fluocinonide can be increased when it is combined with Plumbagin. |
| Trilostane | The serum concentration of Trilostane can be increased when it is combined with Plumbagin. |
| Budesonide | The serum concentration of Budesonide can be increased when it is combined with Plumbagin. |
| Dexamethasone | The serum concentration of Dexamethasone can be increased when it is combined with Plumbagin. |
| Corticotropin | The serum concentration of Corticotropin can be increased when it is combined with Plumbagin. |
| Cortisone acetate | The serum concentration of Cortisone acetate can be increased when it is combined with Plumbagin. |
| Paramethasone | The serum concentration of Paramethasone can be increased when it is combined with Plumbagin. |
| Ciclesonide | The serum concentration of Ciclesonide can be increased when it is combined with Plumbagin. |
| Aldosterone | The serum concentration of Aldosterone can be increased when it is combined with Plumbagin. |
| Fluticasone furoate | The serum concentration of Fluticasone furoate can be increased when it is combined with Plumbagin. |
| Fluprednidene | The serum concentration of Fluprednidene can be increased when it is combined with Plumbagin. |
| Fluocortolone | The serum concentration of Fluocortolone can be increased when it is combined with Plumbagin. |
| Tixocortol | The serum concentration of Tixocortol can be increased when it is combined with Plumbagin. |
| Difluocortolone | The serum concentration of Difluocortolone can be increased when it is combined with Plumbagin. |
| Corticotropin zinc hydroxide | The serum concentration of Corticotropin zinc hydroxide can be increased when it is combined with Plumbagin. |
| Fluprednisolone | The serum concentration of Fluprednisolone can be increased when it is combined with Plumbagin. |
| Meprednisone | The serum concentration of Meprednisone can be increased when it is combined with Plumbagin. |
| Dexamethasone isonicotinate | The serum concentration of Dexamethasone isonicotinate can be increased when it is combined with Plumbagin. |
| Melengestrol | The serum concentration of Melengestrol can be increased when it is combined with Plumbagin. |
| Deflazacort | The serum concentration of Deflazacort can be increased when it is combined with Plumbagin. |
| Cortivazol | The serum concentration of Cortivazol can be increased when it is combined with Plumbagin. |
| Prednylidene | The serum concentration of Prednylidene can be increased when it is combined with Plumbagin. |
| Fluocortin | The serum concentration of Fluocortin can be increased when it is combined with Plumbagin. |
| Fluperolone | The serum concentration of Fluperolone can be increased when it is combined with Plumbagin. |
| Cloprednol | The serum concentration of Cloprednol can be increased when it is combined with Plumbagin. |
| Fluclorolone | The serum concentration of Fluclorolone can be increased when it is combined with Plumbagin. |
| Fluticasone | The serum concentration of Fluticasone can be increased when it is combined with Plumbagin. |
| Mometasone furoate | The serum concentration of Mometasone furoate can be increased when it is combined with Plumbagin. |
| Hydrocortisone acetate | The serum concentration of Hydrocortisone acetate can be increased when it is combined with Plumbagin. |
| Hydrocortisone butyrate | The serum concentration of Hydrocortisone butyrate can be increased when it is combined with Plumbagin. |
| Hydrocortisone cypionate | The serum concentration of Hydrocortisone cypionate can be increased when it is combined with Plumbagin. |
| Hydrocortisone succinate | The serum concentration of Hydrocortisone succinate can be increased when it is combined with Plumbagin. |
| Prednisolone phosphate | The serum concentration of Prednisolone phosphate can be increased when it is combined with Plumbagin. |
| Prednisolone hemisuccinate | The serum concentration of Prednisolone hemisuccinate can be increased when it is combined with Plumbagin. |
| Methylprednisolone aceponate | The serum concentration of Methylprednisolone aceponate can be increased when it is combined with Plumbagin. |
| Methylprednisolone hemisuccinate | The serum concentration of Methylprednisolone hemisuccinate can be increased when it is combined with Plumbagin. |
| Prednisone acetate | The serum concentration of Prednisone acetate can be increased when it is combined with Plumbagin. |
| Dexamethasone acetate | The serum concentration of Dexamethasone acetate can be increased when it is combined with Plumbagin. |
| Clocortolone acetate | The serum concentration of Clocortolone acetate can be increased when it is combined with Plumbagin. |
| Melengestrol acetate | The serum concentration of Melengestrol acetate can be increased when it is combined with Plumbagin. |
| Betamethasone phosphate | The serum concentration of Betamethasone phosphate can be increased when it is combined with Plumbagin. |
| Cortisone | The serum concentration of Cortisone can be increased when it is combined with Plumbagin. |
| Vamorolone | The serum concentration of Vamorolone can be increased when it is combined with Plumbagin. |
| Prednisolone acetate | The serum concentration of Prednisolone acetate can be increased when it is combined with Plumbagin. |
| Fluocortolone pivalate | The serum concentration of Fluocortolone pivalate can be increased when it is combined with Plumbagin. |
| Fluocortolone caproate | The serum concentration of Fluocortolone caproate can be increased when it is combined with Plumbagin. |
| Desoxycortone | The serum concentration of Desoxycortone can be increased when it is combined with Plumbagin. |
| Bosentan | The serum concentration of Plumbagin can be decreased when it is combined with Bosentan. |
| Carbamazepine | The serum concentration of Plumbagin can be decreased when it is combined with Carbamazepine. |
| Flucloxacillin | The metabolism of Plumbagin can be increased when combined with Flucloxacillin. |
| Piperacillin | The therapeutic efficacy of Plumbagin can be decreased when used in combination with Piperacillin. |
| Ampicillin | The therapeutic efficacy of Plumbagin can be decreased when used in combination with Ampicillin. |
| Phenoxymethylpenicillin | The therapeutic efficacy of Plumbagin can be decreased when used in combination with Phenoxymethylpenicillin. |
| Dicloxacillin | The metabolism of Plumbagin can be increased when combined with Dicloxacillin. |
| Carbenicillin | The therapeutic efficacy of Plumbagin can be decreased when used in combination with Carbenicillin. |
| Nafcillin | The metabolism of Plumbagin can be increased when combined with Nafcillin. |
| Oxacillin | The therapeutic efficacy of Plumbagin can be decreased when used in combination with Oxacillin. |
| Hetacillin | The therapeutic efficacy of Plumbagin can be decreased when used in combination with Hetacillin. |
| Benzylpenicilloyl polylysine | The therapeutic efficacy of Plumbagin can be decreased when used in combination with Benzylpenicilloyl polylysine. |
| Mezlocillin | The therapeutic efficacy of Plumbagin can be decreased when used in combination with Mezlocillin. |
| Cyclacillin | The therapeutic efficacy of Plumbagin can be decreased when used in combination with Cyclacillin. |
| Benzylpenicillin | The therapeutic efficacy of Plumbagin can be decreased when used in combination with Benzylpenicillin. |
| Amoxicillin | The therapeutic efficacy of Plumbagin can be decreased when used in combination with Amoxicillin. |
| Azlocillin | The therapeutic efficacy of Plumbagin can be decreased when used in combination with Azlocillin. |
| Cloxacillin | The therapeutic efficacy of Plumbagin can be decreased when used in combination with Cloxacillin. |
| Amdinocillin | The therapeutic efficacy of Plumbagin can be decreased when used in combination with Amdinocillin. |
| Bacampicillin | The therapeutic efficacy of Plumbagin can be decreased when used in combination with Bacampicillin. |
| Meticillin | The therapeutic efficacy of Plumbagin can be decreased when used in combination with Meticillin. |
| Pivampicillin | The therapeutic efficacy of Plumbagin can be decreased when used in combination with Pivampicillin. |
| Pivmecillinam | The therapeutic efficacy of Plumbagin can be decreased when used in combination with Pivmecillinam. |
| Ticarcillin | The therapeutic efficacy of Plumbagin can be decreased when used in combination with Ticarcillin. |
| Azidocillin | The therapeutic efficacy of Plumbagin can be decreased when used in combination with Azidocillin. |
| Carindacillin | The therapeutic efficacy of Plumbagin can be decreased when used in combination with Carindacillin. |
| Procaine benzylpenicillin | The therapeutic efficacy of Plumbagin can be decreased when used in combination with Procaine benzylpenicillin. |
| Sultamicillin | The therapeutic efficacy of Plumbagin can be decreased when used in combination with Sultamicillin. |
| Temocillin | The therapeutic efficacy of Plumbagin can be decreased when used in combination with Temocillin. |
| Epicillin | The therapeutic efficacy of Plumbagin can be decreased when used in combination with Epicillin. |
| Pheneticillin | The therapeutic efficacy of Plumbagin can be decreased when used in combination with Pheneticillin. |