Chlormadinone acetate is a progesterone derivative first synthesized in 1961. In the US, chlormadinone acetate was formerly marketed as a component of the combination drug products Estalor-21 and C-Quens. However, the use of these drugs was associated with the development of mammary tumors in dogs. In 1972, the FDA withdrew its approval for the use of chlormadinone acetate in all products.L43942,L42975 Chlormadinone acetate continues to be used in other countries due to its high contraceptive efficacy and tolerability.A254422,L33974
Fitur visualisasi ini dikembangkan menggunakan pendekatan Graph Theory untuk memetakan hubungan polifarmasi dan molekuler. Entitas (Obat, Target, Gen) direpresentasikan sebagai Simpul (Nodes), sedangkan hubungan biologisnya sebagai Sisi (Edges).
drugbank-id dan name pada skema XML DrugBank.targets/target yang memuat polipeptida sasaran.gene-name dan varian snp-effects.Tata letak grafik menggunakan algoritma Force-Directed Graph (Barnes-Hut). Model fisika ini menerapkan gaya tolak-menolak antar simpul (Gravitasi: -3000) agar tidak tumpang tindih, serta gaya pegas (Spring: 0.04) pada garis penghubung untuk fleksibilitas interaksi.
| Choline C 11 | Chlormadinone acetate may decrease effectiveness of Choline C 11 as a diagnostic agent. |
| Capromab pendetide | Chlormadinone acetate may decrease effectiveness of Capromab pendetide as a diagnostic agent. |
| Gallium Ga-68 gozetotide | Chlormadinone acetate may increase effectiveness of Gallium Ga-68 gozetotide as a diagnostic agent. |
| Piflufolastat F 18 | Chlormadinone acetate may decrease effectiveness of Piflufolastat F 18 as a diagnostic agent. |
| Flotufolastat F-18 | Chlormadinone acetate may decrease effectiveness of Flotufolastat F-18 as a diagnostic agent. |
| Aprepitant | The serum concentration of Chlormadinone acetate can be decreased when it is combined with Aprepitant. |
| Exenatide | Exenatide can cause a decrease in the absorption of Chlormadinone acetate resulting in a reduced serum concentration and potentially a decrease in efficacy. |
| Thalidomide | Chlormadinone acetate may increase the thrombogenic activities of Thalidomide. |
| Tranexamic acid | Chlormadinone acetate may increase the thrombogenic activities of Tranexamic acid. |
| Clobazam | The serum concentration of Chlormadinone acetate can be decreased when it is combined with Clobazam. |
| Griseofulvin | The metabolism of Chlormadinone acetate can be increased when combined with Griseofulvin. |
| Flunisolide | The serum concentration of Flunisolide can be increased when it is combined with Chlormadinone acetate. |
| Fluorometholone | The serum concentration of Fluorometholone can be increased when it is combined with Chlormadinone acetate. |
| Beclomethasone dipropionate | The serum concentration of Beclomethasone dipropionate can be increased when it is combined with Chlormadinone acetate. |
| Betamethasone | The serum concentration of Betamethasone can be increased when it is combined with Chlormadinone acetate. |
| Desoximetasone | The serum concentration of Desoximetasone can be increased when it is combined with Chlormadinone acetate. |
| Fluticasone propionate | The serum concentration of Fluticasone propionate can be increased when it is combined with Chlormadinone acetate. |
| Fluocinolone acetonide | The serum concentration of Fluocinolone acetonide can be increased when it is combined with Chlormadinone acetate. |
| Triamcinolone | The serum concentration of Triamcinolone can be increased when it is combined with Chlormadinone acetate. |
| Prednisone | The serum concentration of Prednisone can be increased when it is combined with Chlormadinone acetate. |
| Flumethasone | The serum concentration of Flumethasone can be increased when it is combined with Chlormadinone acetate. |
| Fludrocortisone | The serum concentration of Fludrocortisone can be increased when it is combined with Chlormadinone acetate. |
| Hydrocortisone | The serum concentration of Hydrocortisone can be increased when it is combined with Chlormadinone acetate. |
| Mometasone | The serum concentration of Mometasone can be increased when it is combined with Chlormadinone acetate. |
| Prednisolone | The serum concentration of Prednisolone can be increased when it is combined with Chlormadinone acetate. |
| Methylprednisolone | The serum concentration of Methylprednisolone can be increased when it is combined with Chlormadinone acetate. |
| Clobetasol propionate | The serum concentration of Clobetasol propionate can be increased when it is combined with Chlormadinone acetate. |
| Fluocinonide | The serum concentration of Fluocinonide can be increased when it is combined with Chlormadinone acetate. |
| Trilostane | The serum concentration of Trilostane can be increased when it is combined with Chlormadinone acetate. |
| Budesonide | The serum concentration of Budesonide can be increased when it is combined with Chlormadinone acetate. |
| Dexamethasone | The serum concentration of Dexamethasone can be increased when it is combined with Chlormadinone acetate. |
| Corticotropin | The serum concentration of Corticotropin can be increased when it is combined with Chlormadinone acetate. |
| Cortisone acetate | The serum concentration of Cortisone acetate can be increased when it is combined with Chlormadinone acetate. |
| Paramethasone | The serum concentration of Paramethasone can be increased when it is combined with Chlormadinone acetate. |
| Ciclesonide | The serum concentration of Ciclesonide can be increased when it is combined with Chlormadinone acetate. |
| Aldosterone | The serum concentration of Aldosterone can be increased when it is combined with Chlormadinone acetate. |
| Fluticasone furoate | The serum concentration of Fluticasone furoate can be increased when it is combined with Chlormadinone acetate. |
| Fluprednidene | The serum concentration of Fluprednidene can be increased when it is combined with Chlormadinone acetate. |
| Fluocortolone | The serum concentration of Fluocortolone can be increased when it is combined with Chlormadinone acetate. |
| Tixocortol | The serum concentration of Tixocortol can be increased when it is combined with Chlormadinone acetate. |
| Difluocortolone | The serum concentration of Difluocortolone can be increased when it is combined with Chlormadinone acetate. |
| Corticotropin zinc hydroxide | The serum concentration of Corticotropin zinc hydroxide can be increased when it is combined with Chlormadinone acetate. |
| Fluprednisolone | The serum concentration of Fluprednisolone can be increased when it is combined with Chlormadinone acetate. |
| Meprednisone | The serum concentration of Meprednisone can be increased when it is combined with Chlormadinone acetate. |
| Dexamethasone isonicotinate | The serum concentration of Dexamethasone isonicotinate can be increased when it is combined with Chlormadinone acetate. |
| Melengestrol | The serum concentration of Melengestrol can be increased when it is combined with Chlormadinone acetate. |
| Deflazacort | The serum concentration of Deflazacort can be increased when it is combined with Chlormadinone acetate. |
| Cortivazol | The serum concentration of Cortivazol can be increased when it is combined with Chlormadinone acetate. |
| Prednylidene | The serum concentration of Prednylidene can be increased when it is combined with Chlormadinone acetate. |
| Fluocortin | The serum concentration of Fluocortin can be increased when it is combined with Chlormadinone acetate. |
| Fluperolone | The serum concentration of Fluperolone can be increased when it is combined with Chlormadinone acetate. |
| Cloprednol | The serum concentration of Cloprednol can be increased when it is combined with Chlormadinone acetate. |
| Fluclorolone | The serum concentration of Fluclorolone can be increased when it is combined with Chlormadinone acetate. |
| Fluticasone | The serum concentration of Fluticasone can be increased when it is combined with Chlormadinone acetate. |
| Mometasone furoate | The serum concentration of Mometasone furoate can be increased when it is combined with Chlormadinone acetate. |
| Hydrocortisone acetate | The serum concentration of Hydrocortisone acetate can be increased when it is combined with Chlormadinone acetate. |
| Hydrocortisone butyrate | The serum concentration of Hydrocortisone butyrate can be increased when it is combined with Chlormadinone acetate. |
| Hydrocortisone cypionate | The serum concentration of Hydrocortisone cypionate can be increased when it is combined with Chlormadinone acetate. |
| Hydrocortisone succinate | The serum concentration of Hydrocortisone succinate can be increased when it is combined with Chlormadinone acetate. |
| Prednisolone phosphate | The serum concentration of Prednisolone phosphate can be increased when it is combined with Chlormadinone acetate. |
| Prednisolone hemisuccinate | The serum concentration of Prednisolone hemisuccinate can be increased when it is combined with Chlormadinone acetate. |
| Methylprednisolone aceponate | The serum concentration of Methylprednisolone aceponate can be increased when it is combined with Chlormadinone acetate. |
| Methylprednisolone hemisuccinate | The serum concentration of Methylprednisolone hemisuccinate can be increased when it is combined with Chlormadinone acetate. |
| Prednisone acetate | The serum concentration of Prednisone acetate can be increased when it is combined with Chlormadinone acetate. |
| Dexamethasone acetate | The serum concentration of Dexamethasone acetate can be increased when it is combined with Chlormadinone acetate. |
| Clocortolone acetate | The serum concentration of Clocortolone acetate can be increased when it is combined with Chlormadinone acetate. |
| Melengestrol acetate | The serum concentration of Melengestrol acetate can be increased when it is combined with Chlormadinone acetate. |
| Betamethasone phosphate | The serum concentration of Betamethasone phosphate can be increased when it is combined with Chlormadinone acetate. |
| Cortisone | The serum concentration of Cortisone can be increased when it is combined with Chlormadinone acetate. |
| Vamorolone | The serum concentration of Vamorolone can be increased when it is combined with Chlormadinone acetate. |
| Prednisolone acetate | The serum concentration of Prednisolone acetate can be increased when it is combined with Chlormadinone acetate. |
| Fluocortolone pivalate | The serum concentration of Fluocortolone pivalate can be increased when it is combined with Chlormadinone acetate. |
| Fluocortolone caproate | The serum concentration of Fluocortolone caproate can be increased when it is combined with Chlormadinone acetate. |
| Desoxycortone | The serum concentration of Desoxycortone can be increased when it is combined with Chlormadinone acetate. |
| Bosentan | The serum concentration of Chlormadinone acetate can be decreased when it is combined with Bosentan. |
| Carbamazepine | The serum concentration of Chlormadinone acetate can be decreased when it is combined with Carbamazepine. |
| Flucloxacillin | The metabolism of Chlormadinone acetate can be increased when combined with Flucloxacillin. |
| Piperacillin | The therapeutic efficacy of Chlormadinone acetate can be decreased when used in combination with Piperacillin. |
| Ampicillin | The therapeutic efficacy of Chlormadinone acetate can be decreased when used in combination with Ampicillin. |
| Phenoxymethylpenicillin | The therapeutic efficacy of Chlormadinone acetate can be decreased when used in combination with Phenoxymethylpenicillin. |
| Dicloxacillin | The metabolism of Chlormadinone acetate can be increased when combined with Dicloxacillin. |
| Carbenicillin | The therapeutic efficacy of Chlormadinone acetate can be decreased when used in combination with Carbenicillin. |
| Nafcillin | The metabolism of Chlormadinone acetate can be increased when combined with Nafcillin. |
| Oxacillin | The therapeutic efficacy of Chlormadinone acetate can be decreased when used in combination with Oxacillin. |
| Hetacillin | The therapeutic efficacy of Chlormadinone acetate can be decreased when used in combination with Hetacillin. |
| Benzylpenicilloyl polylysine | The therapeutic efficacy of Chlormadinone acetate can be decreased when used in combination with Benzylpenicilloyl polylysine. |
| Mezlocillin | The therapeutic efficacy of Chlormadinone acetate can be decreased when used in combination with Mezlocillin. |
| Cyclacillin | The therapeutic efficacy of Chlormadinone acetate can be decreased when used in combination with Cyclacillin. |
| Benzylpenicillin | The therapeutic efficacy of Chlormadinone acetate can be decreased when used in combination with Benzylpenicillin. |
| Amoxicillin | The therapeutic efficacy of Chlormadinone acetate can be decreased when used in combination with Amoxicillin. |
| Azlocillin | The therapeutic efficacy of Chlormadinone acetate can be decreased when used in combination with Azlocillin. |
| Cloxacillin | The therapeutic efficacy of Chlormadinone acetate can be decreased when used in combination with Cloxacillin. |
| Amdinocillin | The therapeutic efficacy of Chlormadinone acetate can be decreased when used in combination with Amdinocillin. |
| Bacampicillin | The therapeutic efficacy of Chlormadinone acetate can be decreased when used in combination with Bacampicillin. |
| Meticillin | The therapeutic efficacy of Chlormadinone acetate can be decreased when used in combination with Meticillin. |
| Pivampicillin | The therapeutic efficacy of Chlormadinone acetate can be decreased when used in combination with Pivampicillin. |
| Pivmecillinam | The therapeutic efficacy of Chlormadinone acetate can be decreased when used in combination with Pivmecillinam. |
| Ticarcillin | The therapeutic efficacy of Chlormadinone acetate can be decreased when used in combination with Ticarcillin. |
| Azidocillin | The therapeutic efficacy of Chlormadinone acetate can be decreased when used in combination with Azidocillin. |
| Carindacillin | The therapeutic efficacy of Chlormadinone acetate can be decreased when used in combination with Carindacillin. |