Posiphen

DB15317

small molecule investigational

Deskripsi

Posiphen is under investigation in clinical trial NCT02925650 (Safety, Tolerability, PK and PD of Posiphen® in Subjects With Early Alzheimer's Disease).

Struktur Molekul 2D

Berat 337.423
Wujud -

Peta Jejaring Molekuler
Legenda: ObatTargetGenEnzim(Panah → menunjukkan arah efek / relasi)TransporterCarrier

Profil Farmakokinetik

Waktu Paruh (Half-Life) -
Volume Distribusi -
Klirens (Clearance) -

Absorpsi

Data absorpsi tidak tersedia.

Metabolisme

Data metabolisme tidak tersedia.

Rute Eliminasi

Data eliminasi belum tersedia.

Interaksi Obat

292 Data
Dipyridamole The therapeutic efficacy of Posiphen can be decreased when used in combination with Dipyridamole.
Ephedrine Posiphen may increase the neuromuscular blocking activities of Ephedrine.
Bambuterol Posiphen may increase the neuromuscular blocking activities of Bambuterol.
Clevidipine Posiphen may increase the neuromuscular blocking activities of Clevidipine.
Sar9, Met (O2)11-Substance P Posiphen may increase the neuromuscular blocking activities of Sar9, Met (O2)11-Substance P.
Mirabegron Posiphen may increase the neuromuscular blocking activities of Mirabegron.
Moxisylyte Posiphen may increase the neuromuscular blocking activities of Moxisylyte.
Propacetamol Posiphen may increase the neuromuscular blocking activities of Propacetamol.
Procaine Posiphen may increase the neuromuscular blocking activities of Procaine.
Cocaine Posiphen may increase the neuromuscular blocking activities of Cocaine.
Trimethaphan Posiphen may increase the neuromuscular blocking activities of Trimethaphan.
Doxacurium Posiphen may increase the neuromuscular blocking activities of Doxacurium.
Chloroprocaine Posiphen may increase the neuromuscular blocking activities of Chloroprocaine.
Tubocurarine Posiphen may increase the neuromuscular blocking activities of Tubocurarine.
Aclidinium Posiphen may increase the neuromuscular blocking activities of Aclidinium.
Butyrylthiocholine Posiphen may increase the neuromuscular blocking activities of Butyrylthiocholine.
Oxybuprocaine Posiphen may increase the neuromuscular blocking activities of Oxybuprocaine.
Benzonatate Posiphen may increase the neuromuscular blocking activities of Benzonatate.
Succinylcholine The metabolism of Succinylcholine can be decreased when combined with Posiphen.
Tramadol The therapeutic efficacy of Tramadol can be decreased when used in combination with Posiphen.
Trospium The therapeutic efficacy of Trospium can be decreased when used in combination with Posiphen.
Oxyphenonium The therapeutic efficacy of Oxyphenonium can be decreased when used in combination with Posiphen.
Butabarbital The therapeutic efficacy of Butabarbital can be decreased when used in combination with Posiphen.
Butalbital The therapeutic efficacy of Butalbital can be decreased when used in combination with Posiphen.
Benzatropine The therapeutic efficacy of Benzatropine can be decreased when used in combination with Posiphen.
Ziprasidone The therapeutic efficacy of Ziprasidone can be decreased when used in combination with Posiphen.
Disopyramide The therapeutic efficacy of Disopyramide can be decreased when used in combination with Posiphen.
Talbutal The therapeutic efficacy of Talbutal can be decreased when used in combination with Posiphen.
Pentobarbital The therapeutic efficacy of Pentobarbital can be decreased when used in combination with Posiphen.
Amitriptyline The therapeutic efficacy of Amitriptyline can be decreased when used in combination with Posiphen.
Ipratropium The therapeutic efficacy of Ipratropium can be decreased when used in combination with Posiphen.
Methadone The therapeutic efficacy of Methadone can be decreased when used in combination with Posiphen.
Olanzapine The therapeutic efficacy of Olanzapine can be decreased when used in combination with Posiphen.
Metixene The therapeutic efficacy of Metixene can be decreased when used in combination with Posiphen.
Terfenadine The therapeutic efficacy of Terfenadine can be decreased when used in combination with Posiphen.
Buclizine The therapeutic efficacy of Buclizine can be decreased when used in combination with Posiphen.
Clozapine The therapeutic efficacy of Clozapine can be decreased when used in combination with Posiphen.
Doxylamine The therapeutic efficacy of Doxylamine can be decreased when used in combination with Posiphen.
Trihexyphenidyl The therapeutic efficacy of Trihexyphenidyl can be decreased when used in combination with Posiphen.
Oxyphencyclimine The therapeutic efficacy of Oxyphencyclimine can be decreased when used in combination with Posiphen.
Procyclidine The therapeutic efficacy of Procyclidine can be decreased when used in combination with Posiphen.
Profenamine The therapeutic efficacy of Profenamine can be decreased when used in combination with Posiphen.
Secobarbital The therapeutic efficacy of Secobarbital can be decreased when used in combination with Posiphen.
Promazine The therapeutic efficacy of Promazine can be decreased when used in combination with Posiphen.
Hyoscyamine The therapeutic efficacy of Hyoscyamine can be decreased when used in combination with Posiphen.
Cyproheptadine The therapeutic efficacy of Cyproheptadine can be decreased when used in combination with Posiphen.
Imipramine The therapeutic efficacy of Imipramine can be decreased when used in combination with Posiphen.
Methscopolamine bromide The therapeutic efficacy of Methscopolamine bromide can be decreased when used in combination with Posiphen.
Metharbital The therapeutic efficacy of Metharbital can be decreased when used in combination with Posiphen.
Fluoxetine The therapeutic efficacy of Fluoxetine can be decreased when used in combination with Posiphen.
Chlorpromazine The therapeutic efficacy of Chlorpromazine can be decreased when used in combination with Posiphen.
Darifenacin The therapeutic efficacy of Darifenacin can be decreased when used in combination with Posiphen.
Tridihexethyl The therapeutic efficacy of Tridihexethyl can be decreased when used in combination with Posiphen.
Triflupromazine The therapeutic efficacy of Triflupromazine can be decreased when used in combination with Posiphen.
Dextromethorphan The therapeutic efficacy of Dextromethorphan can be decreased when used in combination with Posiphen.
Anisotropine methylbromide The therapeutic efficacy of Anisotropine methylbromide can be decreased when used in combination with Posiphen.
Nortriptyline The therapeutic efficacy of Nortriptyline can be decreased when used in combination with Posiphen.
Amoxapine The therapeutic efficacy of Amoxapine can be decreased when used in combination with Posiphen.
Atropine The therapeutic efficacy of Atropine can be decreased when used in combination with Posiphen.
Thiopental The therapeutic efficacy of Thiopental can be decreased when used in combination with Posiphen.
Nicardipine The therapeutic efficacy of Nicardipine can be decreased when used in combination with Posiphen.
Mecamylamine The therapeutic efficacy of Mecamylamine can be decreased when used in combination with Posiphen.
Pirenzepine The therapeutic efficacy of Pirenzepine can be decreased when used in combination with Posiphen.
Paroxetine The therapeutic efficacy of Paroxetine can be decreased when used in combination with Posiphen.
Homatropine methylbromide The therapeutic efficacy of Homatropine methylbromide can be decreased when used in combination with Posiphen.
Scopolamine The therapeutic efficacy of Scopolamine can be decreased when used in combination with Posiphen.
Isoflurane The therapeutic efficacy of Isoflurane can be decreased when used in combination with Posiphen.
Benzquinamide The therapeutic efficacy of Benzquinamide can be decreased when used in combination with Posiphen.
Clidinium The therapeutic efficacy of Clidinium can be decreased when used in combination with Posiphen.
Propiomazine The therapeutic efficacy of Propiomazine can be decreased when used in combination with Posiphen.
Propantheline The therapeutic efficacy of Propantheline can be decreased when used in combination with Posiphen.
Primidone The therapeutic efficacy of Primidone can be decreased when used in combination with Posiphen.
Dicyclomine The therapeutic efficacy of Dicyclomine can be decreased when used in combination with Posiphen.
Biperiden The therapeutic efficacy of Biperiden can be decreased when used in combination with Posiphen.
Brompheniramine The therapeutic efficacy of Brompheniramine can be decreased when used in combination with Posiphen.
Methylphenobarbital The therapeutic efficacy of Methylphenobarbital can be decreased when used in combination with Posiphen.
Quinidine The therapeutic efficacy of Quinidine can be decreased when used in combination with Posiphen.
Amantadine The therapeutic efficacy of Amantadine can be decreased when used in combination with Posiphen.
Maprotiline The therapeutic efficacy of Maprotiline can be decreased when used in combination with Posiphen.
Methantheline The therapeutic efficacy of Methantheline can be decreased when used in combination with Posiphen.
Hexafluronium The therapeutic efficacy of Hexafluronium can be decreased when used in combination with Posiphen.
Cycrimine The therapeutic efficacy of Cycrimine can be decreased when used in combination with Posiphen.
Desloratadine The therapeutic efficacy of Desloratadine can be decreased when used in combination with Posiphen.
Glycopyrronium The therapeutic efficacy of Glycopyrronium can be decreased when used in combination with Posiphen.
Tolterodine The therapeutic efficacy of Tolterodine can be decreased when used in combination with Posiphen.
Oxybutynin The therapeutic efficacy of Oxybutynin can be decreased when used in combination with Posiphen.
Promethazine The therapeutic efficacy of Promethazine can be decreased when used in combination with Posiphen.
Diphenhydramine The therapeutic efficacy of Diphenhydramine can be decreased when used in combination with Posiphen.
Pentolinium The therapeutic efficacy of Pentolinium can be decreased when used in combination with Posiphen.
Doxepin The therapeutic efficacy of Doxepin can be decreased when used in combination with Posiphen.
Flavoxate The therapeutic efficacy of Flavoxate can be decreased when used in combination with Posiphen.
Desipramine The therapeutic efficacy of Desipramine can be decreased when used in combination with Posiphen.
Orphenadrine The therapeutic efficacy of Orphenadrine can be decreased when used in combination with Posiphen.
Phenobarbital The therapeutic efficacy of Phenobarbital can be decreased when used in combination with Posiphen.
Escitalopram The therapeutic efficacy of Escitalopram can be decreased when used in combination with Posiphen.
Quetiapine The therapeutic efficacy of Quetiapine can be decreased when used in combination with Posiphen.
Levacetylmethadol The therapeutic efficacy of Levacetylmethadol can be decreased when used in combination with Posiphen.
Diphenidol The therapeutic efficacy of Diphenidol can be decreased when used in combination with Posiphen.
Aripiprazole The therapeutic efficacy of Aripiprazole can be decreased when used in combination with Posiphen.
Chlorprothixene The therapeutic efficacy of Chlorprothixene can be decreased when used in combination with Posiphen.

Referensi & Sumber

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Sekuens Gen/Protein (FASTA)

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