25-desacetylrifapentine is under investigation in clinical trial NCT00023387 (TBTC Study 25PK: Intensive Pharmacokinetic Study of Three Doses of Rifapentine and 25-Desacetyl Rifapentine).
Fitur visualisasi ini dikembangkan menggunakan pendekatan Graph Theory untuk memetakan hubungan polifarmasi dan molekuler. Entitas (Obat, Target, Gen) direpresentasikan sebagai Simpul (Nodes), sedangkan hubungan biologisnya sebagai Sisi (Edges).
drugbank-id dan name pada skema XML DrugBank.targets/target yang memuat polipeptida sasaran.gene-name dan varian snp-effects.Tata letak grafik menggunakan algoritma Force-Directed Graph (Barnes-Hut). Model fisika ini menerapkan gaya tolak-menolak antar simpul (Gravitasi: -3000) agar tidak tumpang tindih, serta gaya pegas (Spring: 0.04) pada garis penghubung untuk fleksibilitas interaksi.
| Clopidogrel | The therapeutic efficacy of Clopidogrel can be increased when used in combination with 25-desacetylrifapentine. |
| Isoniazid | 25-desacetylrifapentine may increase the hepatotoxic activities of Isoniazid. |
| Mycophenolate mofetil | The serum concentration of Mycophenolate mofetil can be decreased when it is combined with 25-desacetylrifapentine. |
| Mycophenolic acid | The serum concentration of Mycophenolic acid can be decreased when it is combined with 25-desacetylrifapentine. |
| Picosulfuric acid | The therapeutic efficacy of Picosulfuric acid can be decreased when used in combination with 25-desacetylrifapentine. |
| BCG vaccine | The therapeutic efficacy of BCG vaccine can be decreased when used in combination with 25-desacetylrifapentine. |
| Typhoid vaccine | The therapeutic efficacy of Typhoid vaccine can be decreased when used in combination with 25-desacetylrifapentine. |
| Esmolol | The metabolism of Esmolol can be increased when combined with 25-desacetylrifapentine. |
| Betaxolol | The metabolism of Betaxolol can be increased when combined with 25-desacetylrifapentine. |
| Metoprolol | The metabolism of Metoprolol can be increased when combined with 25-desacetylrifapentine. |
| Atenolol | The metabolism of Atenolol can be increased when combined with 25-desacetylrifapentine. |
| Timolol | The metabolism of Timolol can be increased when combined with 25-desacetylrifapentine. |
| Sotalol | The metabolism of Sotalol can be increased when combined with 25-desacetylrifapentine. |
| Propranolol | The metabolism of Propranolol can be increased when combined with 25-desacetylrifapentine. |
| Labetalol | The metabolism of Labetalol can be increased when combined with 25-desacetylrifapentine. |
| Bisoprolol | The metabolism of Bisoprolol can be increased when combined with 25-desacetylrifapentine. |
| Alprenolol | The metabolism of Alprenolol can be increased when combined with 25-desacetylrifapentine. |
| Pindolol | The metabolism of Pindolol can be increased when combined with 25-desacetylrifapentine. |
| Carvedilol | The metabolism of Carvedilol can be increased when combined with 25-desacetylrifapentine. |
| Propafenone | The metabolism of Propafenone can be increased when combined with 25-desacetylrifapentine. |
| Acebutolol | The metabolism of Acebutolol can be increased when combined with 25-desacetylrifapentine. |
| Nadolol | The metabolism of Nadolol can be increased when combined with 25-desacetylrifapentine. |
| Bevantolol | The metabolism of Bevantolol can be increased when combined with 25-desacetylrifapentine. |
| Practolol | The metabolism of Practolol can be increased when combined with 25-desacetylrifapentine. |
| Penbutolol | The metabolism of Penbutolol can be increased when combined with 25-desacetylrifapentine. |
| Oxprenolol | The metabolism of Oxprenolol can be increased when combined with 25-desacetylrifapentine. |
| Dexpropranolol | The metabolism of Dexpropranolol can be increased when combined with 25-desacetylrifapentine. |
| Celiprolol | The metabolism of Celiprolol can be increased when combined with 25-desacetylrifapentine. |
| Nebivolol | The metabolism of Nebivolol can be increased when combined with 25-desacetylrifapentine. |
| Bufuralol | The metabolism of Bufuralol can be increased when combined with 25-desacetylrifapentine. |
| Bopindolol | The metabolism of Bopindolol can be increased when combined with 25-desacetylrifapentine. |
| Bupranolol | The metabolism of Bupranolol can be increased when combined with 25-desacetylrifapentine. |
| Indenolol | The metabolism of Indenolol can be increased when combined with 25-desacetylrifapentine. |
| Arotinolol | The metabolism of Arotinolol can be increased when combined with 25-desacetylrifapentine. |
| Levobetaxolol | The metabolism of Levobetaxolol can be increased when combined with 25-desacetylrifapentine. |
| Talinolol | The metabolism of Talinolol can be increased when combined with 25-desacetylrifapentine. |
| Anisodamine | The metabolism of Anisodamine can be increased when combined with 25-desacetylrifapentine. |
| Bucindolol | The metabolism of Bucindolol can be increased when combined with 25-desacetylrifapentine. |
| Esatenolol | The metabolism of Esatenolol can be increased when combined with 25-desacetylrifapentine. |
| Cloranolol | The metabolism of Cloranolol can be increased when combined with 25-desacetylrifapentine. |
| Mepindolol | The metabolism of Mepindolol can be increased when combined with 25-desacetylrifapentine. |
| Epanolol | The metabolism of Epanolol can be increased when combined with 25-desacetylrifapentine. |
| Tertatolol | The metabolism of Tertatolol can be increased when combined with 25-desacetylrifapentine. |
| Landiolol | The metabolism of Landiolol can be increased when combined with 25-desacetylrifapentine. |
| Dicoumarol | The risk or severity of bleeding can be increased when 25-desacetylrifapentine is combined with Dicoumarol. |
| Phenindione | The risk or severity of bleeding can be increased when 25-desacetylrifapentine is combined with Phenindione. |
| Warfarin | The risk or severity of bleeding can be increased when 25-desacetylrifapentine is combined with Warfarin. |
| Phenprocoumon | The risk or severity of bleeding can be increased when 25-desacetylrifapentine is combined with Phenprocoumon. |
| Acenocoumarol | The risk or severity of bleeding can be increased when 25-desacetylrifapentine is combined with Acenocoumarol. |
| 4-hydroxycoumarin | The risk or severity of bleeding can be increased when 25-desacetylrifapentine is combined with 4-hydroxycoumarin. |
| Coumarin | The risk or severity of bleeding can be increased when 25-desacetylrifapentine is combined with Coumarin. |
| (R)-warfarin | The risk or severity of bleeding can be increased when 25-desacetylrifapentine is combined with (R)-warfarin. |
| Ethyl biscoumacetate | The risk or severity of bleeding can be increased when 25-desacetylrifapentine is combined with Ethyl biscoumacetate. |
| Fluindione | The risk or severity of bleeding can be increased when 25-desacetylrifapentine is combined with Fluindione. |
| Clorindione | The risk or severity of bleeding can be increased when 25-desacetylrifapentine is combined with Clorindione. |
| Diphenadione | The risk or severity of bleeding can be increased when 25-desacetylrifapentine is combined with Diphenadione. |
| Tioclomarol | The risk or severity of bleeding can be increased when 25-desacetylrifapentine is combined with Tioclomarol. |
| (S)-Warfarin | The risk or severity of bleeding can be increased when 25-desacetylrifapentine is combined with (S)-Warfarin. |
| Lactulose | The therapeutic efficacy of Lactulose can be decreased when used in combination with 25-desacetylrifapentine. |
| Vibrio cholerae CVD 103-HgR strain live antigen | The therapeutic efficacy of Vibrio cholerae CVD 103-HgR strain live antigen can be decreased when used in combination with 25-desacetylrifapentine. |
| Estetrol | The therapeutic efficacy of Estetrol can be decreased when used in combination with 25-desacetylrifapentine. |
| Lidocaine | The risk or severity of methemoglobinemia can be increased when 25-desacetylrifapentine is combined with Lidocaine. |
| Ropivacaine | The risk or severity of methemoglobinemia can be increased when 25-desacetylrifapentine is combined with Ropivacaine. |
| Bupivacaine | The risk or severity of methemoglobinemia can be increased when 25-desacetylrifapentine is combined with Bupivacaine. |
| Cinchocaine | The risk or severity of methemoglobinemia can be increased when 25-desacetylrifapentine is combined with Cinchocaine. |
| Dyclonine | The risk or severity of methemoglobinemia can be increased when 25-desacetylrifapentine is combined with Dyclonine. |
| Procaine | The risk or severity of methemoglobinemia can be increased when 25-desacetylrifapentine is combined with Procaine. |
| Prilocaine | The risk or severity of methemoglobinemia can be increased when 25-desacetylrifapentine is combined with Prilocaine. |
| Proparacaine | The risk or severity of methemoglobinemia can be increased when 25-desacetylrifapentine is combined with Proparacaine. |
| Meloxicam | The risk or severity of methemoglobinemia can be increased when 25-desacetylrifapentine is combined with Meloxicam. |
| Oxybuprocaine | The risk or severity of methemoglobinemia can be increased when 25-desacetylrifapentine is combined with Oxybuprocaine. |
| Cocaine | The risk or severity of methemoglobinemia can be increased when 25-desacetylrifapentine is combined with Cocaine. |
| Mepivacaine | The risk or severity of methemoglobinemia can be increased when 25-desacetylrifapentine is combined with Mepivacaine. |
| Levobupivacaine | The risk or severity of methemoglobinemia can be increased when 25-desacetylrifapentine is combined with Levobupivacaine. |
| Diphenhydramine | The risk or severity of methemoglobinemia can be increased when 25-desacetylrifapentine is combined with Diphenhydramine. |
| Benzocaine | The risk or severity of methemoglobinemia can be increased when 25-desacetylrifapentine is combined with Benzocaine. |
| Chloroprocaine | The risk or severity of methemoglobinemia can be increased when 25-desacetylrifapentine is combined with Chloroprocaine. |
| Phenol | The risk or severity of methemoglobinemia can be increased when 25-desacetylrifapentine is combined with Phenol. |
| Tetrodotoxin | The risk or severity of methemoglobinemia can be increased when 25-desacetylrifapentine is combined with Tetrodotoxin. |
| Benzyl alcohol | The risk or severity of methemoglobinemia can be increased when 25-desacetylrifapentine is combined with Benzyl alcohol. |
| Capsaicin | The risk or severity of methemoglobinemia can be increased when 25-desacetylrifapentine is combined with Capsaicin. |
| Etidocaine | The risk or severity of methemoglobinemia can be increased when 25-desacetylrifapentine is combined with Etidocaine. |
| Articaine | The risk or severity of methemoglobinemia can be increased when 25-desacetylrifapentine is combined with Articaine. |
| Tetracaine | The risk or severity of methemoglobinemia can be increased when 25-desacetylrifapentine is combined with Tetracaine. |
| Propoxycaine | The risk or severity of methemoglobinemia can be increased when 25-desacetylrifapentine is combined with Propoxycaine. |
| Pramocaine | The risk or severity of methemoglobinemia can be increased when 25-desacetylrifapentine is combined with Pramocaine. |
| Butamben | The risk or severity of methemoglobinemia can be increased when 25-desacetylrifapentine is combined with Butamben. |
| Butacaine | The risk or severity of methemoglobinemia can be increased when 25-desacetylrifapentine is combined with Butacaine. |
| Oxetacaine | The risk or severity of methemoglobinemia can be increased when 25-desacetylrifapentine is combined with Oxetacaine. |
| Ethyl chloride | The risk or severity of methemoglobinemia can be increased when 25-desacetylrifapentine is combined with Ethyl chloride. |
| Butanilicaine | The risk or severity of methemoglobinemia can be increased when 25-desacetylrifapentine is combined with Butanilicaine. |
| Metabutethamine | The risk or severity of methemoglobinemia can be increased when 25-desacetylrifapentine is combined with Metabutethamine. |
| Quinisocaine | The risk or severity of methemoglobinemia can be increased when 25-desacetylrifapentine is combined with Quinisocaine. |
| Cisatracurium | 25-desacetylrifapentine may increase the neuromuscular blocking activities of Cisatracurium. |
| Ambroxol | The risk or severity of methemoglobinemia can be increased when 25-desacetylrifapentine is combined with Ambroxol. |
| Fecal microbiota | The therapeutic efficacy of Fecal microbiota can be decreased when used in combination with 25-desacetylrifapentine. |