Zolbetuximab

DB15118

biotech approved investigational

Deskripsi

Zolbetuximab is under investigation in clinical trial NCT01630083 (Efficacy and Safety of IMAB362 in Combination With the EOX Regimen for CLDN18.2-positive Gastric Cancer).

Struktur Molekul 2D

Struktur tidak tersedia

Peta Jejaring Molekuler
Legenda: ObatTargetGenEnzim(Panah → menunjukkan arah efek / relasi)TransporterCarrier

Profil Farmakokinetik

Waktu Paruh (Half-Life) -
Volume Distribusi -
Klirens (Clearance) -

Absorpsi

Data absorpsi tidak tersedia.

Metabolisme

Data metabolisme tidak tersedia.

Rute Eliminasi

Data eliminasi belum tersedia.

Interaksi Obat

372 Data
Diethylstilbestrol Diethylstilbestrol may increase the thrombogenic activities of Zolbetuximab.
Chlorotrianisene Chlorotrianisene may increase the thrombogenic activities of Zolbetuximab.
Conjugated estrogens Conjugated estrogens may increase the thrombogenic activities of Zolbetuximab.
Estrone Estrone may increase the thrombogenic activities of Zolbetuximab.
Estradiol Estradiol may increase the thrombogenic activities of Zolbetuximab.
Dienestrol Dienestrol may increase the thrombogenic activities of Zolbetuximab.
Ethinylestradiol Ethinylestradiol may increase the thrombogenic activities of Zolbetuximab.
Mestranol Mestranol may increase the thrombogenic activities of Zolbetuximab.
Estriol Estriol may increase the thrombogenic activities of Zolbetuximab.
Estrone sulfate Estrone sulfate may increase the thrombogenic activities of Zolbetuximab.
Quinestrol Quinestrol may increase the thrombogenic activities of Zolbetuximab.
Hexestrol Hexestrol may increase the thrombogenic activities of Zolbetuximab.
Tibolone Tibolone may increase the thrombogenic activities of Zolbetuximab.
Synthetic Conjugated Estrogens, A Synthetic Conjugated Estrogens, A may increase the thrombogenic activities of Zolbetuximab.
Synthetic Conjugated Estrogens, B Synthetic Conjugated Estrogens, B may increase the thrombogenic activities of Zolbetuximab.
Polyestradiol phosphate Polyestradiol phosphate may increase the thrombogenic activities of Zolbetuximab.
Esterified estrogens Esterified estrogens may increase the thrombogenic activities of Zolbetuximab.
Zeranol Zeranol may increase the thrombogenic activities of Zolbetuximab.
Equol Equol may increase the thrombogenic activities of Zolbetuximab.
Promestriene Promestriene may increase the thrombogenic activities of Zolbetuximab.
Methallenestril Methallenestril may increase the thrombogenic activities of Zolbetuximab.
Epimestrol Epimestrol may increase the thrombogenic activities of Zolbetuximab.
Moxestrol Moxestrol may increase the thrombogenic activities of Zolbetuximab.
Estradiol acetate Estradiol acetate may increase the thrombogenic activities of Zolbetuximab.
Estradiol benzoate Estradiol benzoate may increase the thrombogenic activities of Zolbetuximab.
Estradiol cypionate Estradiol cypionate may increase the thrombogenic activities of Zolbetuximab.
Estradiol valerate Estradiol valerate may increase the thrombogenic activities of Zolbetuximab.
Biochanin A Biochanin A may increase the thrombogenic activities of Zolbetuximab.
Formononetin Formononetin may increase the thrombogenic activities of Zolbetuximab.
Estetrol Estetrol may increase the thrombogenic activities of Zolbetuximab.
Cetuximab The risk or severity of adverse effects can be increased when Cetuximab is combined with Zolbetuximab.
Human immunoglobulin G The risk or severity of adverse effects can be increased when Human immunoglobulin G is combined with Zolbetuximab.
Omalizumab The risk or severity of adverse effects can be increased when Omalizumab is combined with Zolbetuximab.
Adalimumab The risk or severity of adverse effects can be increased when Adalimumab is combined with Zolbetuximab.
Abciximab The risk or severity of adverse effects can be increased when Abciximab is combined with Zolbetuximab.
Gemtuzumab ozogamicin The risk or severity of adverse effects can be increased when Gemtuzumab ozogamicin is combined with Zolbetuximab.
Indium In-111 satumomab pendetide The risk or severity of adverse effects can be increased when Indium In-111 satumomab pendetide is combined with Zolbetuximab.
Infliximab The risk or severity of adverse effects can be increased when Infliximab is combined with Zolbetuximab.
Trastuzumab The risk or severity of adverse effects can be increased when Trastuzumab is combined with Zolbetuximab.
Rituximab The risk or severity of adverse effects can be increased when Rituximab is combined with Zolbetuximab.
Basiliximab The risk or severity of adverse effects can be increased when Basiliximab is combined with Zolbetuximab.
Muromonab The risk or severity of adverse effects can be increased when Muromonab is combined with Zolbetuximab.
Digoxin Immune Fab (Ovine) The risk or severity of adverse effects can be increased when Digoxin Immune Fab (Ovine) is combined with Zolbetuximab.
Ibritumomab tiuxetan The risk or severity of adverse effects can be increased when Ibritumomab tiuxetan is combined with Zolbetuximab.
Tositumomab The risk or severity of adverse effects can be increased when Tositumomab is combined with Zolbetuximab.
Alemtuzumab The risk or severity of adverse effects can be increased when Alemtuzumab is combined with Zolbetuximab.
Capromab pendetide The risk or severity of adverse effects can be increased when Capromab pendetide is combined with Zolbetuximab.
Efalizumab The risk or severity of adverse effects can be increased when Efalizumab is combined with Zolbetuximab.
Antithymocyte immunoglobulin (rabbit) The risk or severity of adverse effects can be increased when Antithymocyte immunoglobulin (rabbit) is combined with Zolbetuximab.
Natalizumab The risk or severity of adverse effects can be increased when Natalizumab is combined with Zolbetuximab.
Palivizumab The risk or severity of adverse effects can be increased when Palivizumab is combined with Zolbetuximab.
Daclizumab The risk or severity of adverse effects can be increased when Daclizumab is combined with Zolbetuximab.
Bevacizumab The risk or severity of adverse effects can be increased when Bevacizumab is combined with Zolbetuximab.
Technetium Tc-99m arcitumomab The risk or severity of adverse effects can be increased when Technetium Tc-99m arcitumomab is combined with Zolbetuximab.
Eculizumab The risk or severity of adverse effects can be increased when Eculizumab is combined with Zolbetuximab.
Panitumumab The risk or severity of adverse effects can be increased when Panitumumab is combined with Zolbetuximab.
Ranibizumab The risk or severity of adverse effects can be increased when Ranibizumab is combined with Zolbetuximab.
Galiximab The risk or severity of adverse effects can be increased when Galiximab is combined with Zolbetuximab.
Pexelizumab The risk or severity of adverse effects can be increased when Pexelizumab is combined with Zolbetuximab.
Afelimomab The risk or severity of adverse effects can be increased when Afelimomab is combined with Zolbetuximab.
Epratuzumab The risk or severity of adverse effects can be increased when Epratuzumab is combined with Zolbetuximab.
Bectumomab The risk or severity of adverse effects can be increased when Bectumomab is combined with Zolbetuximab.
Oregovomab The risk or severity of adverse effects can be increased when Oregovomab is combined with Zolbetuximab.
IGN311 The risk or severity of adverse effects can be increased when IGN311 is combined with Zolbetuximab.
Adecatumumab The risk or severity of adverse effects can be increased when Adecatumumab is combined with Zolbetuximab.
Labetuzumab The risk or severity of adverse effects can be increased when Labetuzumab is combined with Zolbetuximab.
Matuzumab The risk or severity of adverse effects can be increased when Matuzumab is combined with Zolbetuximab.
Fontolizumab The risk or severity of adverse effects can be increased when Fontolizumab is combined with Zolbetuximab.
Bavituximab The risk or severity of adverse effects can be increased when Bavituximab is combined with Zolbetuximab.
CR002 The risk or severity of adverse effects can be increased when CR002 is combined with Zolbetuximab.
Rozrolimupab The risk or severity of adverse effects can be increased when Rozrolimupab is combined with Zolbetuximab.
Girentuximab The risk or severity of adverse effects can be increased when Girentuximab is combined with Zolbetuximab.
Obiltoxaximab The risk or severity of adverse effects can be increased when Obiltoxaximab is combined with Zolbetuximab.
XTL-001 The risk or severity of adverse effects can be increased when XTL-001 is combined with Zolbetuximab.
NAV 1800 The risk or severity of adverse effects can be increased when NAV 1800 is combined with Zolbetuximab.
Briakinumab The risk or severity of adverse effects can be increased when Briakinumab is combined with Zolbetuximab.
Otelixizumab The risk or severity of adverse effects can be increased when Otelixizumab is combined with Zolbetuximab.
AMG 108 The risk or severity of adverse effects can be increased when AMG 108 is combined with Zolbetuximab.
Iratumumab The risk or severity of adverse effects can be increased when Iratumumab is combined with Zolbetuximab.
Enokizumab The risk or severity of adverse effects can be increased when Enokizumab is combined with Zolbetuximab.
Ramucirumab The risk or severity of adverse effects can be increased when Ramucirumab is combined with Zolbetuximab.
Farletuzumab The risk or severity of adverse effects can be increased when Farletuzumab is combined with Zolbetuximab.
Veltuzumab The risk or severity of adverse effects can be increased when Veltuzumab is combined with Zolbetuximab.
Ustekinumab The risk or severity of adverse effects can be increased when Ustekinumab is combined with Zolbetuximab.
Trastuzumab emtansine The risk or severity of adverse effects can be increased when Trastuzumab emtansine is combined with Zolbetuximab.
PRO-542 The risk or severity of adverse effects can be increased when PRO-542 is combined with Zolbetuximab.
TNX-901 The risk or severity of adverse effects can be increased when TNX-901 is combined with Zolbetuximab.
Inotuzumab ozogamicin The risk or severity of adverse effects can be increased when Inotuzumab ozogamicin is combined with Zolbetuximab.
RI 624 The risk or severity of adverse effects can be increased when RI 624 is combined with Zolbetuximab.
Stamulumab The risk or severity of adverse effects can be increased when MYO-029 is combined with Zolbetuximab.
CT-011 The risk or severity of adverse effects can be increased when CT-011 is combined with Zolbetuximab.
Leronlimab The risk or severity of adverse effects can be increased when Leronlimab is combined with Zolbetuximab.
Glembatumumab vedotin The risk or severity of adverse effects can be increased when Glembatumumab vedotin is combined with Zolbetuximab.
Olaratumab The risk or severity of adverse effects can be increased when Olaratumab is combined with Zolbetuximab.
IPH 2101 The risk or severity of adverse effects can be increased when IPH 2101 is combined with Zolbetuximab.
TB-402 The risk or severity of adverse effects can be increased when TB-402 is combined with Zolbetuximab.
Caplacizumab The risk or severity of adverse effects can be increased when Caplacizumab is combined with Zolbetuximab.
IMC-1C11 The risk or severity of adverse effects can be increased when IMC-1C11 is combined with Zolbetuximab.
Eldelumab The risk or severity of adverse effects can be increased when Eldelumab is combined with Zolbetuximab.
Lumiliximab The risk or severity of adverse effects can be increased when Lumiliximab is combined with Zolbetuximab.

Target Protein

Claudin-18 CLDN18

Contoh Produk & Brand

Produk: 3 • International brands: 0
Produk
  • Vyloy
    Injection, powder, for solution • 20 mg/ml • Intravenous • EU • Approved
  • Vyloy
    Injection, powder, for solution • 20 mg/ml • Intravenous • EU • Approved
  • Vyloy
    Injection, powder, for suspension • 20 mg/1mL • Intravenous • US • Approved

Sekuens Gen/Protein (FASTA)

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