Xentuzumab

DB14871

biotech investigational

Deskripsi

Xentuzumab is under investigation in clinical trial NCT02191891 (Xentuzumab (BI 836845) Plus Afatinib in Patients With Epidermal Growth Factor Receptor (EGFR) Mutant Non-small Cell Lung Cancer (NSCLC)).

Struktur Molekul 2D

Struktur tidak tersedia

Peta Jejaring Molekuler
Legenda: ObatTargetGenEnzim(Panah → menunjukkan arah efek / relasi)TransporterCarrier

Profil Farmakokinetik

Waktu Paruh (Half-Life) -
Volume Distribusi -
Klirens (Clearance) -

Absorpsi

Data absorpsi tidak tersedia.

Metabolisme

Data metabolisme tidak tersedia.

Rute Eliminasi

Data eliminasi belum tersedia.

Interaksi Obat

372 Data
Diethylstilbestrol Diethylstilbestrol may increase the thrombogenic activities of Xentuzumab.
Chlorotrianisene Chlorotrianisene may increase the thrombogenic activities of Xentuzumab.
Conjugated estrogens Conjugated estrogens may increase the thrombogenic activities of Xentuzumab.
Estrone Estrone may increase the thrombogenic activities of Xentuzumab.
Estradiol Estradiol may increase the thrombogenic activities of Xentuzumab.
Dienestrol Dienestrol may increase the thrombogenic activities of Xentuzumab.
Ethinylestradiol Ethinylestradiol may increase the thrombogenic activities of Xentuzumab.
Mestranol Mestranol may increase the thrombogenic activities of Xentuzumab.
Estriol Estriol may increase the thrombogenic activities of Xentuzumab.
Estrone sulfate Estrone sulfate may increase the thrombogenic activities of Xentuzumab.
Quinestrol Quinestrol may increase the thrombogenic activities of Xentuzumab.
Hexestrol Hexestrol may increase the thrombogenic activities of Xentuzumab.
Tibolone Tibolone may increase the thrombogenic activities of Xentuzumab.
Synthetic Conjugated Estrogens, A Synthetic Conjugated Estrogens, A may increase the thrombogenic activities of Xentuzumab.
Synthetic Conjugated Estrogens, B Synthetic Conjugated Estrogens, B may increase the thrombogenic activities of Xentuzumab.
Polyestradiol phosphate Polyestradiol phosphate may increase the thrombogenic activities of Xentuzumab.
Esterified estrogens Esterified estrogens may increase the thrombogenic activities of Xentuzumab.
Zeranol Zeranol may increase the thrombogenic activities of Xentuzumab.
Equol Equol may increase the thrombogenic activities of Xentuzumab.
Promestriene Promestriene may increase the thrombogenic activities of Xentuzumab.
Methallenestril Methallenestril may increase the thrombogenic activities of Xentuzumab.
Epimestrol Epimestrol may increase the thrombogenic activities of Xentuzumab.
Moxestrol Moxestrol may increase the thrombogenic activities of Xentuzumab.
Estradiol acetate Estradiol acetate may increase the thrombogenic activities of Xentuzumab.
Estradiol benzoate Estradiol benzoate may increase the thrombogenic activities of Xentuzumab.
Estradiol cypionate Estradiol cypionate may increase the thrombogenic activities of Xentuzumab.
Estradiol valerate Estradiol valerate may increase the thrombogenic activities of Xentuzumab.
Biochanin A Biochanin A may increase the thrombogenic activities of Xentuzumab.
Formononetin Formononetin may increase the thrombogenic activities of Xentuzumab.
Estetrol Estetrol may increase the thrombogenic activities of Xentuzumab.
Cetuximab The risk or severity of adverse effects can be increased when Cetuximab is combined with Xentuzumab.
Human immunoglobulin G The risk or severity of adverse effects can be increased when Human immunoglobulin G is combined with Xentuzumab.
Omalizumab The risk or severity of adverse effects can be increased when Omalizumab is combined with Xentuzumab.
Adalimumab The risk or severity of adverse effects can be increased when Adalimumab is combined with Xentuzumab.
Abciximab The risk or severity of adverse effects can be increased when Abciximab is combined with Xentuzumab.
Gemtuzumab ozogamicin The risk or severity of adverse effects can be increased when Gemtuzumab ozogamicin is combined with Xentuzumab.
Indium In-111 satumomab pendetide The risk or severity of adverse effects can be increased when Indium In-111 satumomab pendetide is combined with Xentuzumab.
Infliximab The risk or severity of adverse effects can be increased when Infliximab is combined with Xentuzumab.
Trastuzumab The risk or severity of adverse effects can be increased when Trastuzumab is combined with Xentuzumab.
Rituximab The risk or severity of adverse effects can be increased when Rituximab is combined with Xentuzumab.
Basiliximab The risk or severity of adverse effects can be increased when Basiliximab is combined with Xentuzumab.
Muromonab The risk or severity of adverse effects can be increased when Muromonab is combined with Xentuzumab.
Digoxin Immune Fab (Ovine) The risk or severity of adverse effects can be increased when Digoxin Immune Fab (Ovine) is combined with Xentuzumab.
Ibritumomab tiuxetan The risk or severity of adverse effects can be increased when Ibritumomab tiuxetan is combined with Xentuzumab.
Tositumomab The risk or severity of adverse effects can be increased when Tositumomab is combined with Xentuzumab.
Alemtuzumab The risk or severity of adverse effects can be increased when Alemtuzumab is combined with Xentuzumab.
Capromab pendetide The risk or severity of adverse effects can be increased when Capromab pendetide is combined with Xentuzumab.
Efalizumab The risk or severity of adverse effects can be increased when Efalizumab is combined with Xentuzumab.
Antithymocyte immunoglobulin (rabbit) The risk or severity of adverse effects can be increased when Antithymocyte immunoglobulin (rabbit) is combined with Xentuzumab.
Natalizumab The risk or severity of adverse effects can be increased when Natalizumab is combined with Xentuzumab.
Palivizumab The risk or severity of adverse effects can be increased when Palivizumab is combined with Xentuzumab.
Daclizumab The risk or severity of adverse effects can be increased when Daclizumab is combined with Xentuzumab.
Bevacizumab The risk or severity of adverse effects can be increased when Bevacizumab is combined with Xentuzumab.
Technetium Tc-99m arcitumomab The risk or severity of adverse effects can be increased when Technetium Tc-99m arcitumomab is combined with Xentuzumab.
Eculizumab The risk or severity of adverse effects can be increased when Eculizumab is combined with Xentuzumab.
Panitumumab The risk or severity of adverse effects can be increased when Panitumumab is combined with Xentuzumab.
Ranibizumab The risk or severity of adverse effects can be increased when Ranibizumab is combined with Xentuzumab.
Galiximab The risk or severity of adverse effects can be increased when Galiximab is combined with Xentuzumab.
Pexelizumab The risk or severity of adverse effects can be increased when Pexelizumab is combined with Xentuzumab.
Afelimomab The risk or severity of adverse effects can be increased when Afelimomab is combined with Xentuzumab.
Epratuzumab The risk or severity of adverse effects can be increased when Epratuzumab is combined with Xentuzumab.
Bectumomab The risk or severity of adverse effects can be increased when Bectumomab is combined with Xentuzumab.
Oregovomab The risk or severity of adverse effects can be increased when Oregovomab is combined with Xentuzumab.
IGN311 The risk or severity of adverse effects can be increased when IGN311 is combined with Xentuzumab.
Adecatumumab The risk or severity of adverse effects can be increased when Adecatumumab is combined with Xentuzumab.
Labetuzumab The risk or severity of adverse effects can be increased when Labetuzumab is combined with Xentuzumab.
Matuzumab The risk or severity of adverse effects can be increased when Matuzumab is combined with Xentuzumab.
Fontolizumab The risk or severity of adverse effects can be increased when Fontolizumab is combined with Xentuzumab.
Bavituximab The risk or severity of adverse effects can be increased when Bavituximab is combined with Xentuzumab.
CR002 The risk or severity of adverse effects can be increased when CR002 is combined with Xentuzumab.
Rozrolimupab The risk or severity of adverse effects can be increased when Rozrolimupab is combined with Xentuzumab.
Girentuximab The risk or severity of adverse effects can be increased when Girentuximab is combined with Xentuzumab.
Obiltoxaximab The risk or severity of adverse effects can be increased when Obiltoxaximab is combined with Xentuzumab.
XTL-001 The risk or severity of adverse effects can be increased when XTL-001 is combined with Xentuzumab.
NAV 1800 The risk or severity of adverse effects can be increased when NAV 1800 is combined with Xentuzumab.
Briakinumab The risk or severity of adverse effects can be increased when Briakinumab is combined with Xentuzumab.
Otelixizumab The risk or severity of adverse effects can be increased when Otelixizumab is combined with Xentuzumab.
AMG 108 The risk or severity of adverse effects can be increased when AMG 108 is combined with Xentuzumab.
Iratumumab The risk or severity of adverse effects can be increased when Iratumumab is combined with Xentuzumab.
Enokizumab The risk or severity of adverse effects can be increased when Enokizumab is combined with Xentuzumab.
Ramucirumab The risk or severity of adverse effects can be increased when Ramucirumab is combined with Xentuzumab.
Farletuzumab The risk or severity of adverse effects can be increased when Farletuzumab is combined with Xentuzumab.
Veltuzumab The risk or severity of adverse effects can be increased when Veltuzumab is combined with Xentuzumab.
Ustekinumab The risk or severity of adverse effects can be increased when Ustekinumab is combined with Xentuzumab.
Trastuzumab emtansine The risk or severity of adverse effects can be increased when Trastuzumab emtansine is combined with Xentuzumab.
PRO-542 The risk or severity of adverse effects can be increased when PRO-542 is combined with Xentuzumab.
TNX-901 The risk or severity of adverse effects can be increased when TNX-901 is combined with Xentuzumab.
Inotuzumab ozogamicin The risk or severity of adverse effects can be increased when Inotuzumab ozogamicin is combined with Xentuzumab.
RI 624 The risk or severity of adverse effects can be increased when RI 624 is combined with Xentuzumab.
Stamulumab The risk or severity of adverse effects can be increased when MYO-029 is combined with Xentuzumab.
CT-011 The risk or severity of adverse effects can be increased when CT-011 is combined with Xentuzumab.
Leronlimab The risk or severity of adverse effects can be increased when Leronlimab is combined with Xentuzumab.
Glembatumumab vedotin The risk or severity of adverse effects can be increased when Glembatumumab vedotin is combined with Xentuzumab.
Olaratumab The risk or severity of adverse effects can be increased when Olaratumab is combined with Xentuzumab.
IPH 2101 The risk or severity of adverse effects can be increased when IPH 2101 is combined with Xentuzumab.
TB-402 The risk or severity of adverse effects can be increased when TB-402 is combined with Xentuzumab.
Caplacizumab The risk or severity of adverse effects can be increased when Caplacizumab is combined with Xentuzumab.
IMC-1C11 The risk or severity of adverse effects can be increased when IMC-1C11 is combined with Xentuzumab.
Eldelumab The risk or severity of adverse effects can be increased when Eldelumab is combined with Xentuzumab.
Lumiliximab The risk or severity of adverse effects can be increased when Lumiliximab is combined with Xentuzumab.

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