Dabigatran

DB14726

small molecule approved investigational

Deskripsi

Dabigatran is the active form of the orally bioavailable prodrug dabigatran etexilate.

Struktur Molekul 2D

Berat 471.521
Wujud -

Peta Jejaring Molekuler
Legenda: ObatTargetGenEnzim(Panah → menunjukkan arah efek / relasi)TransporterCarrier

Profil Farmakokinetik

Waktu Paruh (Half-Life) -
Volume Distribusi -
Klirens (Clearance) -

Absorpsi

Data absorpsi tidak tersedia.

Metabolisme

Data metabolisme tidak tersedia.

Rute Eliminasi

Data eliminasi belum tersedia.

Interaksi Makanan

1 Data
  • 1. Avoid herbs and supplements with anticoagulant/antiplatelet activity. Examples include garlic, ginger, bilberry, danshen, piracetam, and ginkgo biloba.

Interaksi Obat

640 Data
Apixaban Apixaban may increase the anticoagulant activities of Dabigatran.
Dabigatran etexilate Dabigatran etexilate may increase the anticoagulant activities of Dabigatran.
Dasatinib The risk or severity of bleeding and hemorrhage can be increased when Dasatinib is combined with Dabigatran.
Deferasirox The risk or severity of gastrointestinal bleeding can be increased when Dabigatran is combined with Deferasirox.
Ursodeoxycholic acid The risk or severity of bleeding and bruising can be increased when Dabigatran is combined with Ursodeoxycholic acid.
Glycochenodeoxycholic Acid The risk or severity of bleeding and bruising can be increased when Dabigatran is combined with Glycochenodeoxycholic Acid.
Cholic Acid The risk or severity of bleeding and bruising can be increased when Dabigatran is combined with Cholic Acid.
Glycocholic acid The risk or severity of bleeding and bruising can be increased when Dabigatran is combined with Glycocholic acid.
Deoxycholic acid The risk or severity of bleeding and bruising can be increased when Dabigatran is combined with Deoxycholic acid.
Taurocholic acid The risk or severity of bleeding and bruising can be increased when Dabigatran is combined with Taurocholic acid.
Obeticholic acid The risk or severity of bleeding and bruising can be increased when Dabigatran is combined with Obeticholic acid.
Chenodeoxycholic acid The risk or severity of bleeding and bruising can be increased when Dabigatran is combined with Chenodeoxycholic acid.
Taurochenodeoxycholic acid The risk or severity of bleeding and bruising can be increased when Dabigatran is combined with Taurochenodeoxycholic acid.
Tauroursodeoxycholic acid The risk or severity of bleeding and bruising can be increased when Dabigatran is combined with Tauroursodeoxycholic acid.
Bamet-UD2 The risk or severity of bleeding and bruising can be increased when Dabigatran is combined with Bamet-UD2.
Dehydrocholic acid The risk or severity of bleeding and bruising can be increased when Dabigatran is combined with Dehydrocholic acid.
Hyodeoxycholic Acid The risk or severity of bleeding and bruising can be increased when Dabigatran is combined with Hyodeoxycholic Acid.
Edoxaban The risk or severity of bleeding can be increased when Edoxaban is combined with Dabigatran.
Ibrutinib The risk or severity of bleeding and hemorrhage can be increased when Ibrutinib is combined with Dabigatran.
Obinutuzumab The risk or severity of bleeding and hemorrhage can be increased when Dabigatran is combined with Obinutuzumab.
Rivaroxaban Dabigatran may increase the anticoagulant activities of Rivaroxaban.
Sugammadex The risk or severity of bleeding and hemorrhage can be increased when Dabigatran is combined with Sugammadex.
Tibolone Tibolone may increase the anticoagulant activities of Dabigatran.
Tipranavir The risk or severity of bleeding and hemorrhage can be increased when Tipranavir is combined with Dabigatran.
Urokinase Urokinase may increase the anticoagulant activities of Dabigatran.
Vitamin E Vitamin E may increase the anticoagulant activities of Dabigatran.
Vorapaxar The risk or severity of bleeding and hemorrhage can be increased when Vorapaxar is combined with Dabigatran.
Ginkgo biloba Ginkgo biloba may increase the anticoagulant activities of Dabigatran.
Ifosfamide The risk or severity of bleeding can be increased when Ifosfamide is combined with Dabigatran.
Quinine The therapeutic efficacy of Dabigatran can be increased when used in combination with Quinine.
Quinidine The therapeutic efficacy of Dabigatran can be increased when used in combination with Quinidine.
Tamoxifen The risk or severity of bleeding can be increased when Tamoxifen is combined with Dabigatran.
Toremifene The risk or severity of bleeding can be increased when Toremifene is combined with Dabigatran.
Pentoxifylline The therapeutic efficacy of Dabigatran can be increased when used in combination with Pentoxifylline.
Pentosan polysulfate Pentosan polysulfate may increase the anticoagulant activities of Dabigatran.
Levocarnitine The therapeutic efficacy of Dabigatran can be increased when used in combination with Levocarnitine.
Diethylstilbestrol Diethylstilbestrol may decrease the anticoagulant activities of Dabigatran.
Chlorotrianisene Chlorotrianisene may decrease the anticoagulant activities of Dabigatran.
Conjugated estrogens Conjugated estrogens may decrease the anticoagulant activities of Dabigatran.
Mestranol The risk or severity of adverse effects can be increased when Mestranol is combined with Dabigatran.
Estrone sulfate Estrone sulfate may decrease the anticoagulant activities of Dabigatran.
Quinestrol Quinestrol may decrease the anticoagulant activities of Dabigatran.
Hexestrol Hexestrol may decrease the anticoagulant activities of Dabigatran.
Synthetic Conjugated Estrogens, A Synthetic Conjugated Estrogens, A may decrease the anticoagulant activities of Dabigatran.
Synthetic Conjugated Estrogens, B Synthetic Conjugated Estrogens, B may decrease the anticoagulant activities of Dabigatran.
Polyestradiol phosphate Polyestradiol phosphate may decrease the anticoagulant activities of Dabigatran.
Esterified estrogens Esterified estrogens may decrease the anticoagulant activities of Dabigatran.
Zeranol Zeranol may decrease the anticoagulant activities of Dabigatran.
Equol Equol may decrease the anticoagulant activities of Dabigatran.
Methallenestril Methallenestril may decrease the anticoagulant activities of Dabigatran.
Epimestrol Epimestrol may decrease the anticoagulant activities of Dabigatran.
Moxestrol Moxestrol may decrease the anticoagulant activities of Dabigatran.
Estradiol acetate Estradiol acetate may decrease the anticoagulant activities of Dabigatran.
Estradiol benzoate Estradiol benzoate may decrease the anticoagulant activities of Dabigatran.
Estradiol cypionate Estradiol cypionate may decrease the anticoagulant activities of Dabigatran.
Estradiol valerate Estradiol valerate may decrease the anticoagulant activities of Dabigatran.
Biochanin A Biochanin A may decrease the anticoagulant activities of Dabigatran.
Formononetin Formononetin may decrease the anticoagulant activities of Dabigatran.
Estriol Estriol may decrease the anticoagulant activities of Dabigatran.
Limaprost The risk or severity of adverse effects can be increased when Limaprost is combined with Dabigatran.
Icosapent The risk or severity of bleeding and hemorrhage can be increased when Icosapent is combined with Dabigatran.
Mesalazine The risk or severity of bleeding can be increased when Mesalazine is combined with Dabigatran.
Indomethacin The risk or severity of bleeding and hemorrhage can be increased when Indomethacin is combined with Dabigatran.
Nabumetone The risk or severity of bleeding and hemorrhage can be increased when Nabumetone is combined with Dabigatran.
Ketorolac The risk or severity of bleeding and hemorrhage can be increased when Ketorolac is combined with Dabigatran.
Tenoxicam The risk or severity of bleeding and hemorrhage can be increased when Tenoxicam is combined with Dabigatran.
Celecoxib The risk or severity of bleeding and hemorrhage can be increased when Celecoxib is combined with Dabigatran.
Tolmetin The risk or severity of bleeding and hemorrhage can be increased when Tolmetin is combined with Dabigatran.
Rofecoxib The risk or severity of bleeding and hemorrhage can be increased when Rofecoxib is combined with Dabigatran.
Piroxicam The risk or severity of bleeding and hemorrhage can be increased when Piroxicam is combined with Dabigatran.
Fenoprofen The risk or severity of bleeding and hemorrhage can be increased when Fenoprofen is combined with Dabigatran.
Valdecoxib The risk or severity of bleeding and hemorrhage can be increased when Valdecoxib is combined with Dabigatran.
Diclofenac The risk or severity of bleeding and hemorrhage can be increased when Diclofenac is combined with Dabigatran.
Sulindac The risk or severity of bleeding and hemorrhage can be increased when Sulindac is combined with Dabigatran.
Flurbiprofen The risk or severity of bleeding and hemorrhage can be increased when Flurbiprofen is combined with Dabigatran.
Etodolac The risk or severity of bleeding and hemorrhage can be increased when Etodolac is combined with Dabigatran.
Mefenamic acid The risk or severity of bleeding and hemorrhage can be increased when Mefenamic acid is combined with Dabigatran.
Naproxen The risk or severity of bleeding and hemorrhage can be increased when Naproxen is combined with Dabigatran.
Sulfasalazine The risk or severity of bleeding and hemorrhage can be increased when Sulfasalazine is combined with Dabigatran.
Phenylbutazone The risk or severity of bleeding and hemorrhage can be increased when Phenylbutazone is combined with Dabigatran.
Meloxicam The risk or severity of bleeding and hemorrhage can be increased when Meloxicam is combined with Dabigatran.
Carprofen The risk or severity of bleeding and hemorrhage can be increased when Carprofen is combined with Dabigatran.
Diflunisal The risk or severity of bleeding and hemorrhage can be increased when Diflunisal is combined with Dabigatran.
Salicylic acid The risk or severity of bleeding and hemorrhage can be increased when Salicylic acid is combined with Dabigatran.
Meclofenamic acid The risk or severity of bleeding and hemorrhage can be increased when Meclofenamic acid is combined with Dabigatran.
Oxaprozin The risk or severity of bleeding and hemorrhage can be increased when Oxaprozin is combined with Dabigatran.
Ketoprofen The risk or severity of bleeding and hemorrhage can be increased when Ketoprofen is combined with Dabigatran.
Balsalazide The risk or severity of bleeding and hemorrhage can be increased when Balsalazide is combined with Dabigatran.
Olsalazine The risk or severity of bleeding can be increased when Olsalazine is combined with Dabigatran.
Lumiracoxib The risk or severity of bleeding and hemorrhage can be increased when Lumiracoxib is combined with Dabigatran.
Magnesium salicylate The risk or severity of bleeding and hemorrhage can be increased when Magnesium salicylate is combined with Dabigatran.
Salsalate The risk or severity of bleeding and hemorrhage can be increased when Salsalate is combined with Dabigatran.
Choline magnesium trisalicylate The risk or severity of bleeding and hemorrhage can be increased when Choline magnesium trisalicylate is combined with Dabigatran.
Antrafenine The risk or severity of bleeding and hemorrhage can be increased when Antrafenine is combined with Dabigatran.
Aminophenazone The risk or severity of bleeding and hemorrhage can be increased when Aminophenazone is combined with Dabigatran.
Antipyrine The risk or severity of bleeding and hemorrhage can be increased when Antipyrine is combined with Dabigatran.
Tiaprofenic acid The risk or severity of bleeding and hemorrhage can be increased when Tiaprofenic acid is combined with Dabigatran.
Etoricoxib The risk or severity of bleeding and hemorrhage can be increased when Etoricoxib is combined with Dabigatran.
Taxifolin The risk or severity of bleeding and hemorrhage can be increased when Taxifolin is combined with Dabigatran.
Oxyphenbutazone The risk or severity of bleeding and hemorrhage can be increased when Oxyphenbutazone is combined with Dabigatran.

Target Protein

Prothrombin F2

Referensi & Sumber

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International Brands
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