Eslicarbazepine

DB14575

small molecule approved

Deskripsi

Eslicarbazepine is an anti-epileptic medication available commercially as eslicarbazepine acetate.

Struktur Molekul 2D

Berat 254.2839
Wujud -

Peta Jejaring Molekuler
Legenda: ObatTargetGenEnzim(Panah → menunjukkan arah efek / relasi)TransporterCarrier

Profil Farmakokinetik

Waktu Paruh (Half-Life) -
Volume Distribusi -
Klirens (Clearance) -

Absorpsi

Data absorpsi tidak tersedia.

Metabolisme

Data metabolisme tidak tersedia.

Rute Eliminasi

Data eliminasi belum tersedia.

Interaksi Obat

1008 Data
Aripiprazole The metabolism of Aripiprazole can be increased when combined with Eslicarbazepine.
Aripiprazole lauroxil The metabolism of Aripiprazole lauroxil can be increased when combined with Eslicarbazepine.
Cilostazol The serum concentration of Cilostazol can be increased when it is combined with Eslicarbazepine.
Buprenorphine Eslicarbazepine may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Doxylamine Doxylamine may increase the central nervous system depressant (CNS depressant) activities of Eslicarbazepine.
Dronabinol Dronabinol may increase the central nervous system depressant (CNS depressant) activities of Eslicarbazepine.
Droperidol Droperidol may increase the central nervous system depressant (CNS depressant) activities of Eslicarbazepine.
Hydrocodone Eslicarbazepine may increase the central nervous system depressant (CNS depressant) activities of Hydrocodone.
Hydroxyzine Hydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Eslicarbazepine.
Magnesium sulfate The therapeutic efficacy of Eslicarbazepine can be increased when used in combination with Magnesium sulfate.
Methotrimeprazine Eslicarbazepine may increase the central nervous system depressant (CNS depressant) activities of Methotrimeprazine.
Metyrosine Eslicarbazepine may increase the sedative activities of Metyrosine.
Minocycline Minocycline may increase the central nervous system depressant (CNS depressant) activities of Eslicarbazepine.
Mirtazapine Eslicarbazepine may increase the central nervous system depressant (CNS depressant) activities of Mirtazapine.
Nabilone Nabilone may increase the central nervous system depressant (CNS depressant) activities of Eslicarbazepine.
Orphenadrine Eslicarbazepine may increase the central nervous system depressant (CNS depressant) activities of Orphenadrine.
Paraldehyde Eslicarbazepine may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
Pramipexole Eslicarbazepine may increase the sedative activities of Pramipexole.
Ropinirole Eslicarbazepine may increase the sedative activities of Ropinirole.
Rotigotine Eslicarbazepine may increase the sedative activities of Rotigotine.
Rufinamide The risk or severity of adverse effects can be increased when Rufinamide is combined with Eslicarbazepine.
Sodium oxybate Eslicarbazepine may increase the central nervous system depressant (CNS depressant) activities of Sodium oxybate.
Suvorexant Eslicarbazepine may increase the central nervous system depressant (CNS depressant) activities of Suvorexant.
Tapentadol Tapentadol may increase the central nervous system depressant (CNS depressant) activities of Eslicarbazepine.
Thalidomide Eslicarbazepine may increase the central nervous system depressant (CNS depressant) activities of Thalidomide.
Zolpidem Eslicarbazepine may increase the central nervous system depressant (CNS depressant) activities of Zolpidem.
Mefloquine The therapeutic efficacy of Eslicarbazepine can be decreased when used in combination with Mefloquine.
Mianserin The therapeutic efficacy of Eslicarbazepine can be decreased when used in combination with Mianserin.
Orlistat Orlistat can cause a decrease in the absorption of Eslicarbazepine resulting in a reduced serum concentration and potentially a decrease in efficacy.
Topotecan Eslicarbazepine may increase the excretion rate of Topotecan which could result in a lower serum level and potentially a reduction in efficacy.
Methadone The risk or severity of adverse effects can be increased when Methadone is combined with Eslicarbazepine.
Ifosfamide The metabolism of Ifosfamide can be increased when combined with Eslicarbazepine.
Perampanel The metabolism of Perampanel can be increased when combined with Eslicarbazepine.
Warfarin The metabolism of Warfarin can be increased when combined with Eslicarbazepine.
Acenocoumarol The metabolism of Acenocoumarol can be increased when combined with Eslicarbazepine.
(R)-warfarin The metabolism of (R)-warfarin can be increased when combined with Eslicarbazepine.
(S)-Warfarin The metabolism of (S)-Warfarin can be increased when combined with Eslicarbazepine.
R,S-Warfarin alcohol The metabolism of R,S-Warfarin alcohol can be increased when combined with Eslicarbazepine.
S,R-Warfarin alcohol The metabolism of S,R-Warfarin alcohol can be increased when combined with Eslicarbazepine.
Rifampin The metabolism of Eslicarbazepine can be increased when combined with Rifampicin.
Nelfinavir The metabolism of Eslicarbazepine can be increased when combined with Nelfinavir.
Zidovudine The metabolism of Eslicarbazepine can be increased when combined with Zidovudine.
Ritonavir The metabolism of Eslicarbazepine can be increased when combined with Ritonavir.
Lamotrigine The metabolism of Eslicarbazepine can be increased when combined with Lamotrigine.
Efavirenz The metabolism of Eslicarbazepine can be increased when combined with Efavirenz.
Testosterone propionate The metabolism of Eslicarbazepine can be increased when combined with Testosterone propionate.
Tipranavir The metabolism of Eslicarbazepine can be increased when combined with Tipranavir.
Tetracosactide The risk or severity of liver damage can be increased when Tetracosactide is combined with Eslicarbazepine.
Carbamazepine The risk or severity of adverse effects can be increased when Carbamazepine is combined with Eslicarbazepine.
Oxcarbazepine The risk or severity of adverse effects can be increased when Oxcarbazepine is combined with Eslicarbazepine.
Phenytoin The serum concentration of Eslicarbazepine can be decreased when it is combined with Phenytoin.
Mephenytoin The serum concentration of Eslicarbazepine can be decreased when it is combined with Mephenytoin.
Primidone The serum concentration of Eslicarbazepine can be decreased when it is combined with Primidone.
Phenobarbital The serum concentration of Eslicarbazepine can be decreased when it is combined with Phenobarbital.
Fosphenytoin The serum concentration of Eslicarbazepine can be decreased when it is combined with Fosphenytoin.
Ethanol Eslicarbazepine may increase the central nervous system depressant (CNS depressant) activities of Ethanol.
Azelastine Eslicarbazepine may increase the central nervous system depressant (CNS depressant) activities of Azelastine.
Brimonidine Brimonidine may increase the central nervous system depressant (CNS depressant) activities of Eslicarbazepine.
Fluvoxamine The risk or severity of adverse effects can be increased when Eslicarbazepine is combined with Fluvoxamine.
Duloxetine The risk or severity of adverse effects can be increased when Eslicarbazepine is combined with Duloxetine.
Trazodone The risk or severity of adverse effects can be increased when Eslicarbazepine is combined with Trazodone.
Paroxetine The risk or severity of adverse effects can be increased when Eslicarbazepine is combined with Paroxetine.
Sertraline The risk or severity of adverse effects can be increased when Eslicarbazepine is combined with Sertraline.
Sibutramine The risk or severity of adverse effects can be increased when Eslicarbazepine is combined with Sibutramine.
Nefazodone The risk or severity of adverse effects can be increased when Eslicarbazepine is combined with Nefazodone.
Escitalopram The risk or severity of adverse effects can be increased when Eslicarbazepine is combined with Escitalopram.
Zimelidine The risk or severity of adverse effects can be increased when Eslicarbazepine is combined with Zimelidine.
Dapoxetine The risk or severity of adverse effects can be increased when Eslicarbazepine is combined with Dapoxetine.
Desvenlafaxine The risk or severity of adverse effects can be increased when Eslicarbazepine is combined with Desvenlafaxine.
Seproxetine The risk or severity of adverse effects can be increased when Eslicarbazepine is combined with Seproxetine.
Indalpine The risk or severity of adverse effects can be increased when Eslicarbazepine is combined with Indalpine.
Ritanserin The risk or severity of adverse effects can be increased when Eslicarbazepine is combined with Ritanserin.
Alaproclate The risk or severity of adverse effects can be increased when Eslicarbazepine is combined with Alaproclate.
Erlotinib The serum concentration of Erlotinib can be decreased when it is combined with Eslicarbazepine.
Cyproheptadine The risk or severity of CNS depression can be increased when Cyproheptadine is combined with Eslicarbazepine.
Amoxapine The risk or severity of CNS depression can be increased when Amoxapine is combined with Eslicarbazepine.
Propiomazine The risk or severity of CNS depression can be increased when Propiomazine is combined with Eslicarbazepine.
Cocaine The risk or severity of methemoglobinemia can be increased when Eslicarbazepine is combined with Cocaine.
Maprotiline The risk or severity of CNS depression can be increased when Maprotiline is combined with Eslicarbazepine.
Desipramine The risk or severity of CNS depression can be increased when Desipramine is combined with Eslicarbazepine.
Pizotifen The risk or severity of CNS depression can be increased when Pizotifen is combined with Eslicarbazepine.
Dosulepin The risk or severity of CNS depression can be increased when Dosulepin is combined with Eslicarbazepine.
Quetiapine The risk or severity of CNS depression can be increased when Quetiapine is combined with Eslicarbazepine.
Amitriptyline The risk or severity of CNS depression can be increased when Amitriptyline is combined with Eslicarbazepine.
Doxepin The risk or severity of CNS depression can be increased when Doxepin is combined with Eslicarbazepine.
Terfenadine The metabolism of Terfenadine can be increased when combined with Eslicarbazepine.
Clozapine The serum concentration of Clozapine can be decreased when it is combined with Eslicarbazepine.
Zopiclone The risk or severity of adverse effects can be increased when Eslicarbazepine is combined with Zopiclone.
Botulinum toxin type B The risk or severity of CNS depression can be increased when Botulinum toxin type B is combined with Eslicarbazepine.
Botulinum toxin type A The risk or severity of CNS depression can be increased when Botulinum toxin type A is combined with Eslicarbazepine.
Tryptophan The risk or severity of CNS depression can be increased when Tryptophan is combined with Eslicarbazepine.
Baclofen Baclofen may increase the central nervous system depressant (CNS depressant) activities of Eslicarbazepine.
Lorazepam The risk or severity of CNS depression can be increased when Lorazepam is combined with Eslicarbazepine.
Ethchlorvynol The risk or severity of CNS depression can be increased when Ethchlorvynol is combined with Eslicarbazepine.
Succinylcholine The risk or severity of CNS depression can be increased when Succinylcholine is combined with Eslicarbazepine.
Reserpine The risk or severity of CNS depression can be increased when Reserpine is combined with Eslicarbazepine.
Enflurane The risk or severity of CNS depression can be increased when Enflurane is combined with Eslicarbazepine.
Temazepam The risk or severity of CNS depression can be increased when Temazepam is combined with Eslicarbazepine.
Reboxetine The risk or severity of CNS depression can be increased when Reboxetine is combined with Eslicarbazepine.
Butabarbital The risk or severity of CNS depression can be increased when Butabarbital is combined with Eslicarbazepine.

Target Protein

Sodium channel protein type 11 subunit alpha SCN11A
P2X purinoceptor 4 P2RX4

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