Lithium citrate

DB14507

small molecule approved

Deskripsi

Struktur Molekul 2D

Berat 209.92
Wujud -

Peta Jejaring Molekuler
Legenda: ObatTargetGenEnzim(Panah → menunjukkan arah efek / relasi)TransporterCarrier

Profil Farmakokinetik

Waktu Paruh (Half-Life) -
Volume Distribusi -
Klirens (Clearance) -

Absorpsi

Data absorpsi tidak tersedia.

Metabolisme

Data metabolisme tidak tersedia.

Rute Eliminasi

Data eliminasi belum tersedia.

Interaksi Makanan

5 Data
  • 1. Avoid alcohol.
  • 2. Avoid iodine-containing foods and supplements.
  • 3. Drink plenty of fluids. Drink at least 2500 to 3000 mL of fluids daily.
  • 4. Limit caffeine intake.
  • 5. Take with food. Lithium can cause hyponatremia. Include adequate salt in the diet.

Interaksi Obat

1074 Data
Desmopressin The therapeutic efficacy of Desmopressin can be decreased when used in combination with Lithium citrate.
Valsartan The serum concentration of Lithium citrate can be increased when it is combined with Valsartan.
Olmesartan The serum concentration of Lithium citrate can be increased when it is combined with Olmesartan.
Losartan The serum concentration of Lithium citrate can be increased when it is combined with Losartan.
Candesartan cilexetil The serum concentration of Lithium citrate can be increased when it is combined with Candesartan cilexetil.
Eprosartan The serum concentration of Lithium citrate can be increased when it is combined with Eprosartan.
Telmisartan The serum concentration of Lithium citrate can be increased when it is combined with Telmisartan.
Irbesartan The serum concentration of Lithium citrate can be increased when it is combined with Irbesartan.
Forasartan The serum concentration of Lithium citrate can be increased when it is combined with Forasartan.
Saprisartan The serum concentration of Lithium citrate can be increased when it is combined with Saprisartan.
Tasosartan The serum concentration of Lithium citrate can be increased when it is combined with Tasosartan.
Saralasin The serum concentration of Lithium citrate can be increased when it is combined with Saralasin.
Azilsartan medoxomil The serum concentration of Lithium citrate can be increased when it is combined with Azilsartan medoxomil.
Fimasartan The serum concentration of Lithium citrate can be increased when it is combined with Fimasartan.
Candesartan The serum concentration of Lithium citrate can be increased when it is combined with Candesartan.
Ramipril The serum concentration of Lithium citrate can be increased when it is combined with Ramipril.
Fosinopril The serum concentration of Lithium citrate can be increased when it is combined with Fosinopril.
Trandolapril The serum concentration of Lithium citrate can be increased when it is combined with Trandolapril.
Benazepril The serum concentration of Lithium citrate can be increased when it is combined with Benazepril.
Enalapril The serum concentration of Lithium citrate can be increased when it is combined with Enalapril.
Moexipril The serum concentration of Lithium citrate can be increased when it is combined with Moexipril.
Lisinopril The serum concentration of Lithium citrate can be increased when it is combined with Lisinopril.
Perindopril The serum concentration of Lithium citrate can be increased when it is combined with Perindopril.
Quinapril The serum concentration of Lithium citrate can be increased when it is combined with Quinapril.
Omapatrilat The serum concentration of Lithium citrate can be increased when it is combined with Omapatrilat.
Rescinnamine The serum concentration of Lithium citrate can be increased when it is combined with Rescinnamine.
Captopril The serum concentration of Lithium citrate can be increased when it is combined with Captopril.
Cilazapril The serum concentration of Lithium citrate can be increased when it is combined with Cilazapril.
Spirapril The serum concentration of Lithium citrate can be increased when it is combined with Spirapril.
Temocapril The serum concentration of Lithium citrate can be increased when it is combined with Temocapril.
Imidapril The serum concentration of Lithium citrate can be increased when it is combined with Imidapril.
Zofenopril The serum concentration of Lithium citrate can be increased when it is combined with Zofenopril.
Delapril The serum concentration of Lithium citrate can be increased when it is combined with Delapril.
Benazeprilat The serum concentration of Lithium citrate can be increased when it is combined with Benazeprilat.
Fosinoprilat The serum concentration of Lithium citrate can be increased when it is combined with Fosinoprilat.
Ramiprilat The serum concentration of Lithium citrate can be increased when it is combined with Ramiprilat.
Trandolaprilat The serum concentration of Lithium citrate can be increased when it is combined with Trandolaprilat.
Moexiprilat The serum concentration of Lithium citrate can be increased when it is combined with Moexiprilat.
Perindoprilat The serum concentration of Lithium citrate can be increased when it is combined with Perindoprilat.
Quinaprilat The serum concentration of Lithium citrate can be increased when it is combined with Quinaprilat.
Cilazaprilat The serum concentration of Lithium citrate can be increased when it is combined with Cilazaprilat.
Torasemide Torasemide may decrease the excretion rate of Lithium citrate which could result in a higher serum level.
Furosemide Furosemide may decrease the excretion rate of Lithium citrate which could result in a higher serum level.
Bumetanide Bumetanide may decrease the excretion rate of Lithium citrate which could result in a higher serum level.
Etacrynic acid Etacrynic acid may decrease the excretion rate of Lithium citrate which could result in a higher serum level.
Piretanide Piretanide may decrease the excretion rate of Lithium citrate which could result in a higher serum level.
Azosemide Azosemide may decrease the excretion rate of Lithium citrate which could result in a higher serum level.
Tripamide Tripamide may decrease the excretion rate of Lithium citrate which could result in a higher serum level.
Methyclothiazide Methyclothiazide may decrease the excretion rate of Lithium citrate which could result in a higher serum level.
Chlorthalidone Chlorthalidone may decrease the excretion rate of Lithium citrate which could result in a higher serum level.
Bendroflumethiazide Bendroflumethiazide may decrease the excretion rate of Lithium citrate which could result in a higher serum level.
Metolazone Metolazone may decrease the excretion rate of Lithium citrate which could result in a higher serum level.
Benzthiazide Benzthiazide may decrease the excretion rate of Lithium citrate which could result in a higher serum level.
Hydroflumethiazide Hydroflumethiazide may decrease the excretion rate of Lithium citrate which could result in a higher serum level.
Chlorothiazide Chlorothiazide may decrease the excretion rate of Lithium citrate which could result in a higher serum level.
Hydrochlorothiazide Hydrochlorothiazide may decrease the excretion rate of Lithium citrate which could result in a higher serum level.
Trichlormethiazide Trichlormethiazide may decrease the excretion rate of Lithium citrate which could result in a higher serum level.
Polythiazide Polythiazide may decrease the excretion rate of Lithium citrate which could result in a higher serum level.
Quinethazone Quinethazone may decrease the excretion rate of Lithium citrate which could result in a higher serum level.
Cyclopenthiazide Cyclopenthiazide may decrease the excretion rate of Lithium citrate which could result in a higher serum level.
Epitizide Epitizide may decrease the excretion rate of Lithium citrate which could result in a higher serum level.
Phenytoin The risk or severity of adverse effects can be increased when Phenytoin is combined with Lithium citrate.
Fosphenytoin The risk or severity of adverse effects can be increased when Fosphenytoin is combined with Lithium citrate.
Caffeine The serum concentration of Lithium citrate can be decreased when it is combined with Caffeine.
Theophylline The serum concentration of Lithium citrate can be decreased when it is combined with Theophylline.
Mercaptopurine The serum concentration of Lithium citrate can be decreased when it is combined with Mercaptopurine.
Aminophylline The serum concentration of Lithium citrate can be decreased when it is combined with Aminophylline.
Oxtriphylline The serum concentration of Lithium citrate can be decreased when it is combined with Oxtriphylline.
Theobromine The serum concentration of Lithium citrate can be decreased when it is combined with Theobromine.
Fenethylline The serum concentration of Lithium citrate can be decreased when it is combined with Fenethylline.
8-azaguanine The serum concentration of Lithium citrate can be decreased when it is combined with 8-azaguanine.
7,9-Dimethylguanine The serum concentration of Lithium citrate can be decreased when it is combined with 7,9-Dimethylguanine.
Xanthine The serum concentration of Lithium citrate can be decreased when it is combined with Xanthine.
7-Deazaguanine The serum concentration of Lithium citrate can be decreased when it is combined with 7-Deazaguanine.
Guanine The serum concentration of Lithium citrate can be decreased when it is combined with Guanine.
9-Methylguanine The serum concentration of Lithium citrate can be decreased when it is combined with 9-Methylguanine.
Peldesine The serum concentration of Lithium citrate can be decreased when it is combined with Peldesine.
Hypoxanthine The serum concentration of Lithium citrate can be decreased when it is combined with Hypoxanthine.
9-Deazaguanine The serum concentration of Lithium citrate can be decreased when it is combined with 9-Deazaguanine.
Propentofylline The serum concentration of Lithium citrate can be decreased when it is combined with Propentofylline.
Valomaciclovir The serum concentration of Lithium citrate can be decreased when it is combined with Valomaciclovir.
3-isobutyl-1-methyl-7H-xanthine The serum concentration of Lithium citrate can be decreased when it is combined with 3-isobutyl-1-methyl-7H-xanthine.
Uric acid The serum concentration of Lithium citrate can be decreased when it is combined with Uric acid.
Doxofylline The serum concentration of Lithium citrate can be decreased when it is combined with Doxofylline.
6-O-benzylguanine The serum concentration of Lithium citrate can be decreased when it is combined with 6-O-benzylguanine.
Lisofylline The serum concentration of Lithium citrate can be decreased when it is combined with Lisofylline.
Lobucavir The serum concentration of Lithium citrate can be decreased when it is combined with Lobucavir.
Cafedrine The serum concentration of Lithium citrate can be decreased when it is combined with Cafedrine.
Theodrenaline The serum concentration of Lithium citrate can be decreased when it is combined with Theodrenaline.
Bamifylline The serum concentration of Lithium citrate can be decreased when it is combined with Bamifylline.
Proxyphylline The serum concentration of Lithium citrate can be decreased when it is combined with Proxyphylline.
Acefylline The serum concentration of Lithium citrate can be decreased when it is combined with Acefylline.
Etamiphylline The serum concentration of Lithium citrate can be decreased when it is combined with Etamiphylline.
Pentifylline The serum concentration of Lithium citrate can be decreased when it is combined with Pentifylline.
Bufylline The serum concentration of Lithium citrate can be decreased when it is combined with Bufylline.
Bromotheophylline The serum concentration of Lithium citrate can be decreased when it is combined with Bromotheophylline.
Furafylline The serum concentration of Lithium citrate can be decreased when it is combined with Furafylline.
8-chlorotheophylline The serum concentration of Lithium citrate can be decreased when it is combined with 8-chlorotheophylline.
PCS-499 The serum concentration of Lithium citrate can be decreased when it is combined with PCS-499.
Dyphylline The serum concentration of Lithium citrate can be decreased when it is combined with Dyphylline.

Target Protein

Inositol monophosphatase 2 IMPA2
Inositol monophosphatase 1 IMPA1
Glycogen synthase kinase-3 beta GSK3B
Glutamate receptor 3 GRIA3

Referensi & Sumber

Artikel (PubMed)
  • PMID: 20453535
    Quiroz JA, Machado-Vieira R, Zarate CA Jr, Manji HK: Novel insights into lithium's mechanism of action: neurotrophic and neuroprotective effects. Neuropsychobiology. 2010;62(1):50-60. doi: 10.1159/000314310. Epub 2010 May 7.

Contoh Produk & Brand

Produk: 8 • International brands: 0
Produk
  • Lithium
    Solution • 8 meq/5mL • Oral • US • Approved
  • Lithium
    Solution • 8 meq/5mL • Oral • US • Approved
  • Lithium
    Solution • 8 meq/5mL • Oral • US • Approved
  • Lithium
    Solution • 8 meq/5mL • Oral • US • Generic • Approved
  • Lithium
    Solution • 8 meq/5mL • Oral • US • Generic • Approved
  • Lithium
    Solution • 8 meq/5mL • Oral • US • Generic • Approved
  • Lithium Citrate
    Syrup • 8 meq/5mL • Oral • US • Generic • Approved
  • PMS-lithium Citrate
    Syrup • 8 mmol / 5 mL • Oral • Canada • Generic • Approved

Sekuens Gen/Protein (FASTA)

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