Acute iron overdosage can be divided into four stages. In the first stage, which occurs up to six hours after ingestion, the principal symptoms are vomiting and diarrhea. Other symptoms include hypotension, tachycardia and CNS depression ranging from lethargy to coma. The second phase may occur at 6-24 hours after ingestion and is characterized by a temporary remission. In the third phase, gastrointestinal symptoms recur accompanied by shock, metabolic acidosis, coma, hepatic necrosis and jaundice, hypoglycemia, renal failure and pulmonary edema. The fourth phase may occur several weeks after ingestion and is characterized by gastrointestinal obstruction and liver damage. In a young child, 75 milligrams per kilogram is considered extremely dangerous. A dose of 30 milligrams per kilogram can lead to symptoms of toxicity. Estimates of a lethal dosage range from 180 milligrams per kilogram and upwards. A peak serum iron concentration of five micrograms or more per ml is associated with moderate to severe poisoning in many.
Fitur visualisasi ini dikembangkan menggunakan pendekatan Graph Theory untuk memetakan hubungan polifarmasi dan molekuler. Entitas (Obat, Target, Gen) direpresentasikan sebagai Simpul (Nodes), sedangkan hubungan biologisnya sebagai Sisi (Edges).
drugbank-id dan name pada skema XML DrugBank.targets/target yang memuat polipeptida sasaran.gene-name dan varian snp-effects.Tata letak grafik menggunakan algoritma Force-Directed Graph (Barnes-Hut). Model fisika ini menerapkan gaya tolak-menolak antar simpul (Gravitasi: -3000) agar tidak tumpang tindih, serta gaya pegas (Spring: 0.04) pada garis penghubung untuk fleksibilitas interaksi.
| Deferiprone | Ferrous ascorbate can cause a decrease in the absorption of Deferiprone resulting in a reduced serum concentration and potentially a decrease in efficacy. |
| Chlorpropamide | Ferrous ascorbate may decrease the excretion rate of Chlorpropamide which could result in a higher serum level. |
| Mecamylamine | Ferrous ascorbate may increase the excretion rate of Mecamylamine which could result in a lower serum level and potentially a reduction in efficacy. |
| Amphetamine | The serum concentration of Amphetamine can be decreased when it is combined with Ferrous ascorbate. |
| Phentermine | The serum concentration of Phentermine can be decreased when it is combined with Ferrous ascorbate. |
| Pseudoephedrine | The serum concentration of Pseudoephedrine can be decreased when it is combined with Ferrous ascorbate. |
| Benzphetamine | The serum concentration of Benzphetamine can be decreased when it is combined with Ferrous ascorbate. |
| Diethylpropion | The serum concentration of Diethylpropion can be decreased when it is combined with Ferrous ascorbate. |
| Lisdexamfetamine | The serum concentration of Lisdexamfetamine can be decreased when it is combined with Ferrous ascorbate. |
| Mephentermine | The serum concentration of Mephentermine can be decreased when it is combined with Ferrous ascorbate. |
| MMDA | The serum concentration of MMDA can be decreased when it is combined with Ferrous ascorbate. |
| Midomafetamine | The serum concentration of Midomafetamine can be decreased when it is combined with Ferrous ascorbate. |
| 2,5-Dimethoxy-4-ethylamphetamine | The serum concentration of 2,5-Dimethoxy-4-ethylamphetamine can be decreased when it is combined with Ferrous ascorbate. |
| 4-Bromo-2,5-dimethoxyamphetamine | The serum concentration of 4-Bromo-2,5-dimethoxyamphetamine can be decreased when it is combined with Ferrous ascorbate. |
| Tenamfetamine | The serum concentration of Tenamfetamine can be decreased when it is combined with Ferrous ascorbate. |
| Chlorphentermine | The serum concentration of Chlorphentermine can be decreased when it is combined with Ferrous ascorbate. |
| Methylenedioxyethamphetamine | The serum concentration of Methylenedioxyethamphetamine can be decreased when it is combined with Ferrous ascorbate. |
| Dextroamphetamine | The serum concentration of Dextroamphetamine can be decreased when it is combined with Ferrous ascorbate. |
| Metamfetamine | The serum concentration of Metamfetamine can be decreased when it is combined with Ferrous ascorbate. |
| Iofetamine I-123 | The serum concentration of Iofetamine I-123 can be decreased when it is combined with Ferrous ascorbate. |
| Ritobegron | The serum concentration of Ritobegron can be decreased when it is combined with Ferrous ascorbate. |
| Mephedrone | The serum concentration of Mephedrone can be decreased when it is combined with Ferrous ascorbate. |
| Methoxyphenamine | The serum concentration of Methoxyphenamine can be decreased when it is combined with Ferrous ascorbate. |
| Gepefrine | The serum concentration of Gepefrine can be decreased when it is combined with Ferrous ascorbate. |
| 2,5-Dimethoxy-4-ethylthioamphetamine | The serum concentration of 2,5-Dimethoxy-4-ethylthioamphetamine can be decreased when it is combined with Ferrous ascorbate. |
| Phendimetrazine | The serum concentration of Phendimetrazine can be decreased when it is combined with Ferrous ascorbate. |
| Dolutegravir | The serum concentration of Dolutegravir can be decreased when it is combined with Ferrous ascorbate. |
| Raltegravir | The serum concentration of Raltegravir can be decreased when it is combined with Ferrous ascorbate. |
| Cabotegravir | The serum concentration of Cabotegravir can be decreased when it is combined with Ferrous ascorbate. |