Lomerizine is a diphenylmethylpiperazine calcium channel blockerA245378, A245383 with relatively selective central nervous system (CNS) effects.A245383
This drug is used to prophylactically treat migrainesA245368, A245373 and is also being investigated against eye-related diseases that are associated with local circulatory disturbances, an example being normal-tension glaucoma.A245378
Fitur visualisasi ini dikembangkan menggunakan pendekatan Graph Theory untuk memetakan hubungan polifarmasi dan molekuler. Entitas (Obat, Target, Gen) direpresentasikan sebagai Simpul (Nodes), sedangkan hubungan biologisnya sebagai Sisi (Edges).
drugbank-id dan name pada skema XML DrugBank.targets/target yang memuat polipeptida sasaran.gene-name dan varian snp-effects.Tata letak grafik menggunakan algoritma Force-Directed Graph (Barnes-Hut). Model fisika ini menerapkan gaya tolak-menolak antar simpul (Gravitasi: -3000) agar tidak tumpang tindih, serta gaya pegas (Spring: 0.04) pada garis penghubung untuk fleksibilitas interaksi.
| Ceritinib | Lomerizine may increase the bradycardic activities of Ceritinib. |
| Ivabradine | Lomerizine may increase the bradycardic activities of Ivabradine. |
| Ruxolitinib | Ruxolitinib may increase the bradycardic activities of Lomerizine. |
| Cimetidine | The serum concentration of Lomerizine can be increased when it is combined with Cimetidine. |
| Clopidogrel | The therapeutic efficacy of Clopidogrel can be decreased when used in combination with Lomerizine. |
| Efavirenz | The serum concentration of Lomerizine can be decreased when it is combined with Efavirenz. |
| Melatonin | The therapeutic efficacy of Lomerizine can be decreased when used in combination with Melatonin. |
| Nafcillin | The therapeutic efficacy of Lomerizine can be decreased when used in combination with Nafcillin. |
| Nitroprusside | Lomerizine may increase the hypotensive activities of Nitroprusside. |
| Dantrolene | The risk or severity of hyperkalemia can be increased when Dantrolene is combined with Lomerizine. |
| Lithium citrate | The risk or severity of adverse effects can be increased when Lomerizine is combined with Lithium citrate. |
| Lithium carbonate | The risk or severity of adverse effects can be increased when Lomerizine is combined with Lithium carbonate. |
| Lithium hydroxide | The risk or severity of adverse effects can be increased when Lomerizine is combined with Lithium hydroxide. |
| Boceprevir | The serum concentration of Lomerizine can be increased when it is combined with Boceprevir. |
| Ibutilide | Ibutilide may increase the arrhythmogenic activities of Lomerizine. |
| Hyoscyamine | Hyoscyamine may increase the arrhythmogenic activities of Lomerizine. |
| Atropine | Atropine may increase the arrhythmogenic activities of Lomerizine. |
| Adenosine | Adenosine may increase the arrhythmogenic activities of Lomerizine. |
| Moricizine | Moricizine may increase the arrhythmogenic activities of Lomerizine. |
| Levosimendan | Levosimendan may increase the arrhythmogenic activities of Lomerizine. |
| Procainamide | Procainamide may increase the arrhythmogenic activities of Lomerizine. |
| Tocainide | Tocainide may increase the arrhythmogenic activities of Lomerizine. |
| Flecainide | Flecainide may increase the arrhythmogenic activities of Lomerizine. |
| Encainide | Encainide may increase the arrhythmogenic activities of Lomerizine. |
| Ajmaline | Ajmaline may increase the arrhythmogenic activities of Lomerizine. |
| Aprindine | Aprindine may increase the arrhythmogenic activities of Lomerizine. |
| Azimilide | Azimilide may increase the arrhythmogenic activities of Lomerizine. |
| Tedisamil | Tedisamil may increase the arrhythmogenic activities of Lomerizine. |
| Vernakalant | Vernakalant may increase the arrhythmogenic activities of Lomerizine. |
| Cariporide | Cariporide may increase the arrhythmogenic activities of Lomerizine. |
| Xylometazoline | Xylometazoline may increase the arrhythmogenic activities of Lomerizine. |
| Sparteine | Sparteine may increase the arrhythmogenic activities of Lomerizine. |
| Fasudil | Fasudil may increase the arrhythmogenic activities of Lomerizine. |
| Melperone | Melperone may increase the arrhythmogenic activities of Lomerizine. |
| Tropisetron | Tropisetron may increase the arrhythmogenic activities of Lomerizine. |
| Simendan | Simendan may increase the arrhythmogenic activities of Lomerizine. |
| Spiradoline | Spiradoline may increase the arrhythmogenic activities of Lomerizine. |
| Pilsicainide | Pilsicainide may increase the arrhythmogenic activities of Lomerizine. |
| Cicletanine | Cicletanine may increase the arrhythmogenic activities of Lomerizine. |
| Cibenzoline | Cibenzoline may increase the arrhythmogenic activities of Lomerizine. |
| Nizofenone | Nizofenone may increase the arrhythmogenic activities of Lomerizine. |
| Prajmaline | Prajmaline may increase the arrhythmogenic activities of Lomerizine. |
| Tiracizine | Tiracizine may increase the arrhythmogenic activities of Lomerizine. |
| Ethacizine | Ethacizine may increase the arrhythmogenic activities of Lomerizine. |
| Lorajmine | Lorajmine may increase the arrhythmogenic activities of Lomerizine. |
| Bunaftine | Bunaftine may increase the arrhythmogenic activities of Lomerizine. |
| Lorcainide | Lorcainide may increase the arrhythmogenic activities of Lomerizine. |
| Hydroquinine | Hydroquinine may increase the arrhythmogenic activities of Lomerizine. |
| Fosfructose | Fosfructose may increase the arrhythmogenic activities of Lomerizine. |
| Carteolol | Lomerizine may increase the arrhythmogenic activities of Carteolol. |
| Metipranolol | Lomerizine may increase the arrhythmogenic activities of Metipranolol. |
| Bioallethrin | Lomerizine may increase the arrhythmogenic activities of Bioallethrin. |
| Hydroquinidine | Lomerizine may increase the arrhythmogenic activities of Hydroquinidine. |
| SOR-C13 | Lomerizine may increase the arrhythmogenic activities of SOR-C13. |
| Acetyldigitoxin | Acetyldigitoxin may increase the arrhythmogenic activities of Lomerizine. |
| Deslanoside | Deslanoside may increase the arrhythmogenic activities of Lomerizine. |
| Cymarin | Cymarin may increase the arrhythmogenic activities of Lomerizine. |
| Niguldipine | Niguldipine may increase the arrhythmogenic activities of Lomerizine. |
| Bretylium | Bretylium may increase the arrhythmogenic activities of Lomerizine. |
| Isradipine | Isradipine may increase the arrhythmogenic activities of Lomerizine. |
| Trimethadione | Trimethadione may increase the arrhythmogenic activities of Lomerizine. |
| Amlodipine | Amlodipine may increase the arrhythmogenic activities of Lomerizine. |
| Nimodipine | Nimodipine may increase the arrhythmogenic activities of Lomerizine. |
| Lercanidipine | Lercanidipine may increase the arrhythmogenic activities of Lomerizine. |
| Cinnarizine | Cinnarizine may increase the arrhythmogenic activities of Lomerizine. |
| Levomenthol | Levomenthol may increase the arrhythmogenic activities of Lomerizine. |
| Zonisamide | Zonisamide may increase the arrhythmogenic activities of Lomerizine. |
| Nitrendipine | Nitrendipine may increase the arrhythmogenic activities of Lomerizine. |
| Perhexiline | Perhexiline may increase the arrhythmogenic activities of Lomerizine. |
| Bepridil | Bepridil may increase the arrhythmogenic activities of Lomerizine. |
| Nimesulide | Nimesulide may increase the arrhythmogenic activities of Lomerizine. |
| Prenylamine | Prenylamine may increase the arrhythmogenic activities of Lomerizine. |
| Cyclandelate | Cyclandelate may increase the arrhythmogenic activities of Lomerizine. |
| Flunarizine | Flunarizine may increase the arrhythmogenic activities of Lomerizine. |
| Fluspirilene | Fluspirilene may increase the arrhythmogenic activities of Lomerizine. |
| Clevidipine | Clevidipine may increase the arrhythmogenic activities of Lomerizine. |
| Methsuximide | Methsuximide may increase the arrhythmogenic activities of Lomerizine. |
| Seletracetam | Seletracetam may increase the arrhythmogenic activities of Lomerizine. |
| Nylidrin | Nylidrin may increase the arrhythmogenic activities of Lomerizine. |
| Ziconotide | Ziconotide may increase the arrhythmogenic activities of Lomerizine. |
| Dotarizine | Dotarizine may increase the arrhythmogenic activities of Lomerizine. |
| Nilvadipine | Nilvadipine may increase the arrhythmogenic activities of Lomerizine. |
| Tranilast | Tranilast may increase the arrhythmogenic activities of Lomerizine. |
| Agmatine | Agmatine may increase the arrhythmogenic activities of Lomerizine. |
| Fendiline | Fendiline may increase the arrhythmogenic activities of Lomerizine. |
| Eperisone | Eperisone may increase the arrhythmogenic activities of Lomerizine. |
| Trimebutine | Trimebutine may increase the arrhythmogenic activities of Lomerizine. |
| Pinaverium | Pinaverium may increase the arrhythmogenic activities of Lomerizine. |
| Nicorandil | Nicorandil may increase the arrhythmogenic activities of Lomerizine. |
| Barnidipine | Barnidipine may increase the arrhythmogenic activities of Lomerizine. |
| Aranidipine | Aranidipine may increase the arrhythmogenic activities of Lomerizine. |
| Azelnidipine | Azelnidipine may increase the arrhythmogenic activities of Lomerizine. |
| Benidipine | Benidipine may increase the arrhythmogenic activities of Lomerizine. |
| Cilnidipine | Cilnidipine may increase the arrhythmogenic activities of Lomerizine. |
| Darodipine | Darodipine may increase the arrhythmogenic activities of Lomerizine. |
| Efonidipine | Efonidipine may increase the arrhythmogenic activities of Lomerizine. |
| Lacidipine | Lacidipine may increase the arrhythmogenic activities of Lomerizine. |
| Manidipine | Manidipine may increase the arrhythmogenic activities of Lomerizine. |
| Niludipine | Niludipine may increase the arrhythmogenic activities of Lomerizine. |
| Carboxyamidotriazole | Carboxyamidotriazole may increase the arrhythmogenic activities of Lomerizine. |