A cyclododecadepsipeptide ionophore antibiotic produced by Streptomyces fulvissimus and related to the enniatins. It is composed of 3 moles each of L-valine, D-alpha-hydroxyisovaleric acid, D-valine, and L-lactic acid linked alternately to form a 36-membered ring. (From Merck Index, 11th ed) Valinomycin is a potassium selective ionophore and is commonly used as a tool in biochemical studies.
Fitur visualisasi ini dikembangkan menggunakan pendekatan Graph Theory untuk memetakan hubungan polifarmasi dan molekuler. Entitas (Obat, Target, Gen) direpresentasikan sebagai Simpul (Nodes), sedangkan hubungan biologisnya sebagai Sisi (Edges).
drugbank-id dan name pada skema XML DrugBank.targets/target yang memuat polipeptida sasaran.gene-name dan varian snp-effects.Tata letak grafik menggunakan algoritma Force-Directed Graph (Barnes-Hut). Model fisika ini menerapkan gaya tolak-menolak antar simpul (Gravitasi: -3000) agar tidak tumpang tindih, serta gaya pegas (Spring: 0.04) pada garis penghubung untuk fleksibilitas interaksi.
| Glycochenodeoxycholic Acid | Valinomycin may decrease the excretion rate of Glycochenodeoxycholic Acid which could result in a higher serum level. |
| Pravastatin | Valinomycin may decrease the excretion rate of Pravastatin which could result in a higher serum level. |
| Fluvoxamine | Valinomycin may decrease the excretion rate of Fluvoxamine which could result in a higher serum level. |
| Nelfinavir | Valinomycin may decrease the excretion rate of Nelfinavir which could result in a higher serum level. |
| Glimepiride | Valinomycin may decrease the excretion rate of Glimepiride which could result in a higher serum level. |
| Indinavir | Valinomycin may decrease the excretion rate of Indinavir which could result in a higher serum level. |
| Diethylstilbestrol | Valinomycin may decrease the excretion rate of Diethylstilbestrol which could result in a higher serum level. |
| Isradipine | Valinomycin may decrease the excretion rate of Isradipine which could result in a higher serum level. |
| Flucloxacillin | Valinomycin may decrease the excretion rate of Flucloxacillin which could result in a higher serum level. |
| Indomethacin | Valinomycin may decrease the excretion rate of Indomethacin which could result in a higher serum level. |
| Atenolol | Valinomycin may decrease the excretion rate of Atenolol which could result in a higher serum level. |
| Terfenadine | Valinomycin may decrease the excretion rate of Terfenadine which could result in a higher serum level. |
| Rosiglitazone | Valinomycin may decrease the excretion rate of Rosiglitazone which could result in a higher serum level. |
| Cerivastatin | Valinomycin may decrease the excretion rate of Cerivastatin which could result in a higher serum level. |
| Loratadine | Valinomycin may decrease the excretion rate of Loratadine which could result in a higher serum level. |
| Ritonavir | Valinomycin may decrease the excretion rate of Ritonavir which could result in a higher serum level. |
| Atropine | Valinomycin may decrease the excretion rate of Atropine which could result in a higher serum level. |
| Diclofenac | Valinomycin may decrease the excretion rate of Diclofenac which could result in a higher serum level. |
| Imatinib | Valinomycin may decrease the excretion rate of Imatinib which could result in a higher serum level. |
| Nicardipine | Valinomycin may decrease the excretion rate of Nicardipine which could result in a higher serum level. |
| Efavirenz | Valinomycin may decrease the excretion rate of Efavirenz which could result in a higher serum level. |
| Simvastatin | Valinomycin may decrease the excretion rate of Simvastatin which could result in a higher serum level. |
| Fluorescein | Valinomycin may decrease the excretion rate of Fluorescein which could result in a higher serum level. |
| Nitrofurantoin | Valinomycin may decrease the excretion rate of Nitrofurantoin which could result in a higher serum level. |
| Naproxen | Valinomycin may decrease the excretion rate of Naproxen which could result in a higher serum level. |
| Disulfiram | Valinomycin may decrease the excretion rate of Disulfiram which could result in a higher serum level. |
| Cefaclor | Valinomycin may decrease the excretion rate of Cefaclor which could result in a higher serum level. |
| Mifepristone | Valinomycin may decrease the excretion rate of Mifepristone which could result in a higher serum level. |
| Tinidazole | Valinomycin may decrease the excretion rate of Tinidazole which could result in a higher serum level. |
| Repaglinide | Valinomycin may decrease the excretion rate of Repaglinide which could result in a higher serum level. |
| Telmisartan | Valinomycin may decrease the excretion rate of Telmisartan which could result in a higher serum level. |
| Ezetimibe | Valinomycin may decrease the excretion rate of Ezetimibe which could result in a higher serum level. |
| Dipyridamole | Valinomycin may decrease the excretion rate of Dipyridamole which could result in a higher serum level. |
| Sulfamethoxazole | Valinomycin may decrease the excretion rate of Sulfamethoxazole which could result in a higher serum level. |
| Felodipine | Valinomycin may decrease the excretion rate of Felodipine which could result in a higher serum level. |
| Fenofibrate | Valinomycin may decrease the excretion rate of Fenofibrate which could result in a higher serum level. |
| Nitrendipine | Valinomycin may decrease the excretion rate of Nitrendipine which could result in a higher serum level. |
| Glipizide | Valinomycin may decrease the excretion rate of Glipizide which could result in a higher serum level. |
| Atazanavir | Valinomycin may decrease the excretion rate of Atazanavir which could result in a higher serum level. |
| Atorvastatin | Valinomycin may decrease the excretion rate of Atorvastatin which could result in a higher serum level. |
| Rosuvastatin | Valinomycin may decrease the excretion rate of Rosuvastatin which could result in a higher serum level. |
| Nifedipine | Valinomycin may decrease the excretion rate of Nifedipine which could result in a higher serum level. |
| Sulfinpyrazone | Valinomycin may decrease the excretion rate of Sulfinpyrazone which could result in a higher serum level. |
| Nefazodone | Valinomycin may decrease the excretion rate of Nefazodone which could result in a higher serum level. |
| Ofloxacin | Valinomycin may decrease the excretion rate of Ofloxacin which could result in a higher serum level. |
| Clarithromycin | Valinomycin may decrease the excretion rate of Clarithromycin which could result in a higher serum level. |
| Budesonide | Valinomycin may decrease the excretion rate of Budesonide which could result in a higher serum level. |
| Saquinavir | Valinomycin may decrease the excretion rate of Saquinavir which could result in a higher serum level. |
| Taurocholic acid | Valinomycin may decrease the excretion rate of Taurocholic acid which could result in a higher serum level. |
| Prasterone sulfate | Valinomycin may decrease the excretion rate of Prasterone sulfate which could result in a higher serum level. |
| Indocyanine green acid form | Valinomycin may decrease the excretion rate of Indocyanine green acid form which could result in a higher serum level. |
| Benzbromarone | Valinomycin may decrease the excretion rate of Benzbromarone which could result in a higher serum level. |
| Pilsicainide | Valinomycin may decrease the excretion rate of Pilsicainide which could result in a higher serum level. |
| Dihydroergocristine | Valinomycin may decrease the excretion rate of Dihydroergocristine which could result in a higher serum level. |
| Glycyrrhizic acid | Valinomycin may decrease the excretion rate of Glycyrrhizic acid which could result in a higher serum level. |
| Ranolazine | Valinomycin may decrease the excretion rate of Ranolazine which could result in a higher serum level. |
| Belantamab mafodotin | Valinomycin may decrease the excretion rate of Belantamab mafodotin which could result in a higher serum level. |
| Picosulfuric acid | The therapeutic efficacy of Picosulfuric acid can be decreased when used in combination with Valinomycin. |
| BCG vaccine | The therapeutic efficacy of BCG vaccine can be decreased when used in combination with Valinomycin. |
| Typhoid vaccine | The therapeutic efficacy of Typhoid vaccine can be decreased when used in combination with Valinomycin. |
| Troglitazone | The risk or severity of liver damage can be increased when Troglitazone is combined with Valinomycin. |
| Erythromycin | Valinomycin may decrease the excretion rate of Erythromycin which could result in a higher serum level. |
| Reserpine | The risk or severity of liver damage can be increased when Reserpine is combined with Valinomycin. |
| Progesterone | The risk or severity of liver damage can be increased when Progesterone is combined with Valinomycin. |
| Chlorpromazine | The risk or severity of liver damage can be increased when Chlorpromazine is combined with Valinomycin. |
| Cimetidine | The risk or severity of liver damage can be increased when Cimetidine is combined with Valinomycin. |
| Bosentan | The risk or severity of liver damage can be increased when Bosentan is combined with Valinomycin. |
| Tamoxifen | The risk or severity of liver damage can be increased when Tamoxifen is combined with Valinomycin. |
| Tipranavir | Valinomycin may decrease the excretion rate of Tipranavir which could result in a higher serum level. |
| Ethinylestradiol | The risk or severity of liver damage can be increased when Ethinylestradiol is combined with Valinomycin. |
| Glyburide | Valinomycin may decrease the excretion rate of Glyburide which could result in a higher serum level. |
| Ketoconazole | Valinomycin may decrease the excretion rate of Ketoconazole which could result in a higher serum level. |
| Ursodeoxycholic acid | Valinomycin may decrease the excretion rate of Ursodeoxycholic acid which could result in a higher serum level. |
| Cholic Acid | Valinomycin may decrease the excretion rate of Cholic Acid which could result in a higher serum level. |
| Fusidic acid | The risk or severity of liver damage can be increased when Fusidic acid is combined with Valinomycin. |
| Simeprevir | The risk or severity of liver damage can be increased when Simeprevir is combined with Valinomycin. |
| Lenvatinib | The risk or severity of liver damage can be increased when Lenvatinib is combined with Valinomycin. |
| Celecoxib | The risk or severity of liver damage can be increased when Celecoxib is combined with Valinomycin. |
| Cyclosporine | The risk or severity of liver damage can be increased when Cyclosporine is combined with Valinomycin. |
| Quinidine | The risk or severity of liver damage can be increased when Quinidine is combined with Valinomycin. |
| Olmesartan | The risk or severity of liver damage can be increased when Olmesartan is combined with Valinomycin. |
| Pralsetinib | The risk or severity of liver damage can be increased when Valinomycin is combined with Pralsetinib. |
| Vinblastine | Valinomycin may decrease the excretion rate of Vinblastine which could result in a higher serum level. |
| Astemizole | Valinomycin may decrease the excretion rate of Astemizole which could result in a higher serum level. |
| Digoxin | Valinomycin may decrease the excretion rate of Digoxin which could result in a higher serum level. |
| Vincristine | Valinomycin may decrease the excretion rate of Vincristine which could result in a higher serum level. |
| Doxorubicin | Valinomycin may decrease the excretion rate of Doxorubicin which could result in a higher serum level. |
| Paclitaxel | Valinomycin may decrease the excretion rate of Paclitaxel which could result in a higher serum level. |
| Dicoumarol | The risk or severity of bleeding can be increased when Valinomycin is combined with Dicoumarol. |
| Phenindione | The risk or severity of bleeding can be increased when Valinomycin is combined with Phenindione. |
| Warfarin | The risk or severity of bleeding can be increased when Valinomycin is combined with Warfarin. |
| Phenprocoumon | The risk or severity of bleeding can be increased when Valinomycin is combined with Phenprocoumon. |
| Acenocoumarol | The risk or severity of bleeding can be increased when Valinomycin is combined with Acenocoumarol. |
| 4-hydroxycoumarin | The risk or severity of bleeding can be increased when Valinomycin is combined with 4-hydroxycoumarin. |
| Coumarin | The risk or severity of bleeding can be increased when Valinomycin is combined with Coumarin. |
| (R)-warfarin | The risk or severity of bleeding can be increased when Valinomycin is combined with (R)-warfarin. |
| Ethyl biscoumacetate | The risk or severity of bleeding can be increased when Valinomycin is combined with Ethyl biscoumacetate. |
| Fluindione | The risk or severity of bleeding can be increased when Valinomycin is combined with Fluindione. |
| Clorindione | The risk or severity of bleeding can be increased when Valinomycin is combined with Clorindione. |
| Diphenadione | The risk or severity of bleeding can be increased when Valinomycin is combined with Diphenadione. |