Warfarin consists of a racemic mixture of two active enantiomers—R- and S- forms—each of which is cleared by different pathways. S-warfarin is 2-5 times more potent than the R-isomer in producing an anticoagulant response.A7166
Fitur visualisasi ini dikembangkan menggunakan pendekatan Graph Theory untuk memetakan hubungan polifarmasi dan molekuler. Entitas (Obat, Target, Gen) direpresentasikan sebagai Simpul (Nodes), sedangkan hubungan biologisnya sebagai Sisi (Edges).
drugbank-id dan name pada skema XML DrugBank.targets/target yang memuat polipeptida sasaran.gene-name dan varian snp-effects.Tata letak grafik menggunakan algoritma Force-Directed Graph (Barnes-Hut). Model fisika ini menerapkan gaya tolak-menolak antar simpul (Gravitasi: -3000) agar tidak tumpang tindih, serta gaya pegas (Spring: 0.04) pada garis penghubung untuk fleksibilitas interaksi.
| Apixaban | Apixaban may increase the anticoagulant activities of (S)-Warfarin. |
| Dabigatran etexilate | Dabigatran etexilate may increase the anticoagulant activities of (S)-Warfarin. |
| Dasatinib | The risk or severity of bleeding and hemorrhage can be increased when Dasatinib is combined with (S)-Warfarin. |
| Deferasirox | The risk or severity of gastrointestinal bleeding can be increased when (S)-Warfarin is combined with Deferasirox. |
| Ursodeoxycholic acid | The risk or severity of bleeding and bruising can be increased when (S)-Warfarin is combined with Ursodeoxycholic acid. |
| Glycochenodeoxycholic Acid | The risk or severity of bleeding and bruising can be increased when (S)-Warfarin is combined with Glycochenodeoxycholic Acid. |
| Cholic Acid | The risk or severity of bleeding and bruising can be increased when (S)-Warfarin is combined with Cholic Acid. |
| Glycocholic acid | The risk or severity of bleeding and bruising can be increased when (S)-Warfarin is combined with Glycocholic acid. |
| Deoxycholic acid | The risk or severity of bleeding and bruising can be increased when (S)-Warfarin is combined with Deoxycholic acid. |
| Taurocholic acid | The risk or severity of bleeding and bruising can be increased when (S)-Warfarin is combined with Taurocholic acid. |
| Chenodeoxycholic acid | The risk or severity of bleeding and bruising can be increased when (S)-Warfarin is combined with Chenodeoxycholic acid. |
| Taurochenodeoxycholic acid | The risk or severity of bleeding and bruising can be increased when (S)-Warfarin is combined with Taurochenodeoxycholic acid. |
| Tauroursodeoxycholic acid | The risk or severity of bleeding and bruising can be increased when (S)-Warfarin is combined with Tauroursodeoxycholic acid. |
| Bamet-UD2 | The risk or severity of bleeding and bruising can be increased when (S)-Warfarin is combined with Bamet-UD2. |
| Dehydrocholic acid | The risk or severity of bleeding and bruising can be increased when (S)-Warfarin is combined with Dehydrocholic acid. |
| Hyodeoxycholic Acid | The risk or severity of bleeding and bruising can be increased when (S)-Warfarin is combined with Hyodeoxycholic Acid. |
| Edoxaban | The risk or severity of bleeding can be increased when Edoxaban is combined with (S)-Warfarin. |
| Ibrutinib | The risk or severity of bleeding and hemorrhage can be increased when Ibrutinib is combined with (S)-Warfarin. |
| Obinutuzumab | The risk or severity of bleeding and hemorrhage can be increased when (S)-Warfarin is combined with Obinutuzumab. |
| Rivaroxaban | (S)-Warfarin may increase the anticoagulant activities of Rivaroxaban. |
| Sugammadex | The risk or severity of bleeding and hemorrhage can be increased when (S)-Warfarin is combined with Sugammadex. |
| Tibolone | Tibolone may increase the anticoagulant activities of (S)-Warfarin. |
| Tipranavir | The risk or severity of bleeding and hemorrhage can be increased when Tipranavir is combined with (S)-Warfarin. |
| Urokinase | Urokinase may increase the anticoagulant activities of (S)-Warfarin. |
| Vitamin E | Vitamin E may increase the anticoagulant activities of (S)-Warfarin. |
| Vorapaxar | The risk or severity of bleeding and hemorrhage can be increased when Vorapaxar is combined with (S)-Warfarin. |
| Dabrafenib | The serum concentration of (S)-Warfarin can be decreased when it is combined with Dabrafenib. |
| Luliconazole | The serum concentration of (S)-Warfarin can be increased when it is combined with Luliconazole. |
| Mirtazapine | Mirtazapine may increase the anticoagulant activities of (S)-Warfarin. |
| Sorafenib | The risk or severity of bleeding can be increased when Sorafenib is combined with (S)-Warfarin. |
| Mifepristone | The serum concentration of (S)-Warfarin can be increased when it is combined with Mifepristone. |
| Gemcitabine | The therapeutic efficacy of (S)-Warfarin can be increased when used in combination with Gemcitabine. |
| Trilostane | Trilostane may increase the anticoagulant activities of (S)-Warfarin. |
| Ciclesonide | Ciclesonide may increase the anticoagulant activities of (S)-Warfarin. |
| Aldosterone | Aldosterone may increase the anticoagulant activities of (S)-Warfarin. |
| Fluprednidene | Fluprednidene may increase the anticoagulant activities of (S)-Warfarin. |
| Tixocortol | Tixocortol may increase the anticoagulant activities of (S)-Warfarin. |
| Fluprednisolone | Fluprednisolone may increase the anticoagulant activities of (S)-Warfarin. |
| Meprednisone | Meprednisone may increase the anticoagulant activities of (S)-Warfarin. |
| Melengestrol | Melengestrol may increase the anticoagulant activities of (S)-Warfarin. |
| Deflazacort | Deflazacort may increase the anticoagulant activities of (S)-Warfarin. |
| Cortivazol | Cortivazol may increase the anticoagulant activities of (S)-Warfarin. |
| Prednylidene | Prednylidene may increase the anticoagulant activities of (S)-Warfarin. |
| Fluocortin | Fluocortin may increase the anticoagulant activities of (S)-Warfarin. |
| Fluperolone | Fluperolone may increase the anticoagulant activities of (S)-Warfarin. |
| Cloprednol | Cloprednol may increase the anticoagulant activities of (S)-Warfarin. |
| Fluclorolone | Fluclorolone may increase the anticoagulant activities of (S)-Warfarin. |
| Mometasone furoate | Mometasone furoate may increase the anticoagulant activities of (S)-Warfarin. |
| Hydrocortisone cypionate | Hydrocortisone cypionate may increase the anticoagulant activities of (S)-Warfarin. |
| Prednisolone phosphate | Prednisolone phosphate may increase the anticoagulant activities of (S)-Warfarin. |
| Prednisolone hemisuccinate | Prednisolone hemisuccinate may increase the anticoagulant activities of (S)-Warfarin. |
| Methylprednisolone hemisuccinate | Methylprednisolone hemisuccinate may increase the anticoagulant activities of (S)-Warfarin. |
| Prednisone acetate | Prednisone acetate may increase the anticoagulant activities of (S)-Warfarin. |
| Clocortolone acetate | Clocortolone acetate may increase the anticoagulant activities of (S)-Warfarin. |
| Melengestrol acetate | Melengestrol acetate may increase the anticoagulant activities of (S)-Warfarin. |
| Betamethasone phosphate | Betamethasone phosphate may increase the anticoagulant activities of (S)-Warfarin. |
| Cortisone | Cortisone may increase the anticoagulant activities of (S)-Warfarin. |
| Paramethasone | Paramethasone may increase the anticoagulant activities of (S)-Warfarin. |
| Fluticasone furoate | Fluticasone furoate may increase the anticoagulant activities of (S)-Warfarin. |
| Fluticasone | Fluticasone may increase the anticoagulant activities of (S)-Warfarin. |
| Fludrocortisone | Fludrocortisone may increase the anticoagulant activities of (S)-Warfarin. |
| Prednisone | Prednisone may increase the anticoagulant activities of (S)-Warfarin. |
| Clobetasol propionate | Clobetasol propionate may increase the anticoagulant activities of (S)-Warfarin. |
| Fluocinonide | Fluocinonide may increase the anticoagulant activities of (S)-Warfarin. |
| Hydrocortisone butyrate | Hydrocortisone butyrate may increase the anticoagulant activities of (S)-Warfarin. |
| Desoximetasone | Desoximetasone may increase the anticoagulant activities of (S)-Warfarin. |
| Mometasone | Mometasone may increase the anticoagulant activities of (S)-Warfarin. |
| Fluocortolone | Fluocortolone may increase the anticoagulant activities of (S)-Warfarin. |
| Prednisolone acetate | Prednisolone acetate may increase the anticoagulant activities of (S)-Warfarin. |
| Fluorometholone | Fluorometholone may increase the anticoagulant activities of (S)-Warfarin. |
| Difluocortolone | Difluocortolone may increase the anticoagulant activities of (S)-Warfarin. |
| Flumethasone | Flumethasone may increase the anticoagulant activities of (S)-Warfarin. |
| Methylprednisolone aceponate | Methylprednisolone aceponate may increase the anticoagulant activities of (S)-Warfarin. |
| Ritonavir | The serum concentration of (S)-Warfarin can be decreased when it is combined with Ritonavir. |
| Erlotinib | The serum concentration of (S)-Warfarin can be increased when it is combined with Erlotinib. |
| Tigecycline | The serum concentration of (S)-Warfarin can be increased when it is combined with Tigecycline. |
| Imatinib | Imatinib may increase the anticoagulant activities of (S)-Warfarin. |
| Trazodone | Trazodone may decrease the anticoagulant activities of (S)-Warfarin. |
| Allopurinol | The risk or severity of bleeding can be increased when Allopurinol is combined with (S)-Warfarin. |
| Viloxazine | The metabolism of (S)-Warfarin can be decreased when combined with Viloxazine. |
| Methylene blue | The serum concentration of (S)-Warfarin can be increased when it is combined with Methylene blue. |
| Azelastine | The metabolism of (S)-Warfarin can be decreased when combined with Azelastine. |
| Abiraterone | The metabolism of (S)-Warfarin can be decreased when combined with Abiraterone. |
| Aldesleukin | The serum concentration of (S)-Warfarin can be increased when it is combined with Aldesleukin. |
| Octreotide | The serum concentration of (S)-Warfarin can be increased when it is combined with Octreotide. |
| Fluvoxamine | The serum concentration of (S)-Warfarin can be increased when it is combined with Fluvoxamine. |
| Fluconazole | The serum concentration of (S)-Warfarin can be increased when it is combined with Fluconazole. |
| Citalopram | The risk or severity of bleeding can be increased when (S)-Warfarin is combined with Citalopram. |
| Lovastatin | The risk or severity of bleeding can be increased when Lovastatin is combined with (S)-Warfarin. |
| Ziprasidone | The serum concentration of (S)-Warfarin can be increased when it is combined with Ziprasidone. |
| Cabergoline | The serum concentration of (S)-Warfarin can be increased when it is combined with Cabergoline. |
| Diethylstilbestrol | The serum concentration of (S)-Warfarin can be increased when it is combined with Diethylstilbestrol. |
| Isradipine | The serum concentration of (S)-Warfarin can be increased when it is combined with Isradipine. |
| Valproic acid | The serum concentration of (S)-Warfarin can be increased when it is combined with Valproic acid. |
| Dihydroergotamine | The serum concentration of (S)-Warfarin can be increased when it is combined with Dihydroergotamine. |
| Diltiazem | The serum concentration of (S)-Warfarin can be increased when it is combined with Diltiazem. |
| Methylergometrine | The serum concentration of (S)-Warfarin can be increased when it is combined with Methylergometrine. |
| Mefloquine | The serum concentration of (S)-Warfarin can be increased when it is combined with Mefloquine. |
| Nitric Oxide | The serum concentration of (S)-Warfarin can be increased when it is combined with Nitric Oxide. |
| Teniposide | The serum concentration of (S)-Warfarin can be increased when it is combined with Teniposide. |