Furafylline

DB14029

small molecule experimental

Deskripsi

Furafylline is a derivative of methylxanthine derivative. It was developed on the context of asthma as a long-acting alternative for theophylline.

Struktur Molekul 2D

Berat 293.345
Wujud solid

Peta Jejaring Molekuler
Legenda: ObatTargetGenEnzim(Panah → menunjukkan arah efek / relasi)TransporterCarrier

Profil Farmakokinetik

Waktu Paruh (Half-Life) -
Volume Distribusi -
Klirens (Clearance) -

Absorpsi

Data absorpsi tidak tersedia.

Metabolisme

Data metabolisme tidak tersedia.

Rute Eliminasi

Data eliminasi belum tersedia.

Interaksi Obat

539 Data
Regadenoson Furafylline may decrease effectiveness of Regadenoson as a diagnostic agent.
Adalimumab The serum concentration of Furafylline can be decreased when it is combined with Adalimumab.
Adenosine The therapeutic efficacy of Adenosine can be decreased when used in combination with Furafylline.
Allopurinol The serum concentration of Furafylline can be increased when it is combined with Allopurinol.
Carbamazepine The serum concentration of Furafylline can be decreased when it is combined with Carbamazepine.
Cimetidine The metabolism of Furafylline can be decreased when combined with Cimetidine.
Disulfiram The serum concentration of Furafylline can be increased when it is combined with Disulfiram.
Febuxostat The serum concentration of the active metabolites of Furafylline can be increased when Furafylline is used in combination with Febuxostat.
Fluvoxamine The metabolism of Furafylline can be decreased when combined with Fluvoxamine.
Formoterol The risk or severity of hypokalemia can be increased when Furafylline is combined with Formoterol.
Indacaterol The risk or severity of adverse effects can be increased when Furafylline is combined with Indacaterol.
Isoniazid The serum concentration of Furafylline can be increased when it is combined with Isoniazid.
Lithium citrate The serum concentration of Lithium citrate can be decreased when it is combined with Furafylline.
Lithium carbonate The serum concentration of Lithium carbonate can be decreased when it is combined with Furafylline.
Lithium hydroxide The serum concentration of Lithium hydroxide can be decreased when it is combined with Furafylline.
Mexiletine The metabolism of Furafylline can be decreased when combined with Mexiletine.
Olodaterol Furafylline may increase the hyperkalemic activities of Olodaterol.
Pancuronium The therapeutic efficacy of Pancuronium can be decreased when used in combination with Furafylline.
Pentoxifylline The serum concentration of Furafylline can be increased when it is combined with Pentoxifylline.
Phenytoin The serum concentration of Furafylline can be decreased when it is combined with Phenytoin.
Fosphenytoin The serum concentration of Furafylline can be decreased when it is combined with Fosphenytoin.
Propafenone The serum concentration of Furafylline can be increased when it is combined with Propafenone.
Quinine The serum concentration of Furafylline can be increased when it is combined with Quinine.
Quinidine The serum concentration of Furafylline can be increased when it is combined with Quinidine.
Riociguat Furafylline may increase the hypotensive activities of Riociguat.
Thiabendazole The metabolism of Furafylline can be decreased when combined with Thiabendazole.
Ticlopidine The metabolism of Furafylline can be decreased when combined with Ticlopidine.
Zafirlukast The serum concentration of Zafirlukast can be decreased when it is combined with Furafylline.
Zolmitriptan The metabolism of Zolmitriptan can be decreased when combined with Furafylline.
Probenecid The serum concentration of Furafylline can be increased when it is combined with Probenecid.
Isoprenaline The serum concentration of Furafylline can be decreased when it is combined with Isoprenaline.
Amphetamine The risk or severity of adverse effects can be increased when Amphetamine is combined with Furafylline.
Phentermine The risk or severity of adverse effects can be increased when Phentermine is combined with Furafylline.
Midodrine The risk or severity of adverse effects can be increased when Midodrine is combined with Furafylline.
Norepinephrine The risk or severity of adverse effects can be increased when Norepinephrine is combined with Furafylline.
Phenylephrine The risk or severity of adverse effects can be increased when Phenylephrine is combined with Furafylline.
Phenylpropanolamine The risk or severity of adverse effects can be increased when Phenylpropanolamine is combined with Furafylline.
Labetalol The risk or severity of adverse effects can be increased when Labetalol is combined with Furafylline.
Metaraminol The risk or severity of adverse effects can be increased when Metaraminol is combined with Furafylline.
Epinephrine The risk or severity of adverse effects can be increased when Epinephrine is combined with Furafylline.
Methoxamine The risk or severity of adverse effects can be increased when Methoxamine is combined with Furafylline.
Orciprenaline The risk or severity of adverse effects can be increased when Orciprenaline is combined with Furafylline.
Phenmetrazine The risk or severity of adverse effects can be increased when Phenmetrazine is combined with Furafylline.
Dobutamine The risk or severity of adverse effects can be increased when Dobutamine is combined with Furafylline.
Pseudoephedrine The risk or severity of adverse effects can be increased when Pseudoephedrine is combined with Furafylline.
Benzphetamine The risk or severity of adverse effects can be increased when Benzphetamine is combined with Furafylline.
Ritodrine The risk or severity of adverse effects can be increased when Ritodrine is combined with Furafylline.
Terbutaline The risk or severity of adverse effects can be increased when Terbutaline is combined with Furafylline.
Oxymetazoline The risk or severity of adverse effects can be increased when Oxymetazoline is combined with Furafylline.
Diethylpropion The risk or severity of adverse effects can be increased when Diethylpropion is combined with Furafylline.
Dopamine The risk or severity of adverse effects can be increased when Dopamine is combined with Furafylline.
Acebutolol The risk or severity of adverse effects can be increased when Acebutolol is combined with Furafylline.
Lisdexamfetamine The risk or severity of adverse effects can be increased when Lisdexamfetamine is combined with Furafylline.
Fenoterol The risk or severity of adverse effects can be increased when Fenoterol is combined with Furafylline.
Ephedrine The risk or severity of adverse effects can be increased when Ephedrine is combined with Furafylline.
Mephentermine The risk or severity of adverse effects can be increased when Mephentermine is combined with Furafylline.
Procaterol The risk or severity of adverse effects can be increased when Procaterol is combined with Furafylline.
Clenbuterol The risk or severity of adverse effects can be increased when Clenbuterol is combined with Furafylline.
MMDA The risk or severity of adverse effects can be increased when MMDA is combined with Furafylline.
Midomafetamine The risk or severity of adverse effects can be increased when Midomafetamine is combined with Furafylline.
2,5-Dimethoxy-4-ethylamphetamine The risk or severity of adverse effects can be increased when 2,5-Dimethoxy-4-ethylamphetamine is combined with Furafylline.
4-Bromo-2,5-dimethoxyamphetamine The risk or severity of adverse effects can be increased when 4-Bromo-2,5-dimethoxyamphetamine is combined with Furafylline.
Tenamfetamine The risk or severity of adverse effects can be increased when Tenamfetamine is combined with Furafylline.
Chlorphentermine The risk or severity of adverse effects can be increased when Chlorphentermine is combined with Furafylline.
Methylenedioxyethamphetamine The risk or severity of adverse effects can be increased when Methylenedioxyethamphetamine is combined with Furafylline.
Dextroamphetamine The risk or severity of adverse effects can be increased when Dextroamphetamine is combined with Furafylline.
Metamfetamine The risk or severity of adverse effects can be increased when Metamfetamine is combined with Furafylline.
Celiprolol The risk or severity of adverse effects can be increased when Celiprolol is combined with Furafylline.
Nylidrin The risk or severity of adverse effects can be increased when Nylidrin is combined with Furafylline.
Tetryzoline The risk or severity of adverse effects can be increased when Tetryzoline is combined with Furafylline.
Tyramine The risk or severity of adverse effects can be increased when Tyramine is combined with Furafylline.
Isoxsuprine The risk or severity of adverse effects can be increased when Isoxsuprine is combined with Furafylline.
Etilefrine The risk or severity of adverse effects can be increased when Etilefrine is combined with Furafylline.
Synephrine The risk or severity of adverse effects can be increased when Synephrine is combined with Furafylline.
Hydroxyamphetamine The risk or severity of adverse effects can be increased when Hydroxyamphetamine is combined with Furafylline.
Iofetamine I-123 The risk or severity of adverse effects can be increased when Iofetamine I-123 is combined with Furafylline.
Racepinephrine The risk or severity of adverse effects can be increased when Racepinephrine is combined with Furafylline.
Ritobegron The risk or severity of adverse effects can be increased when Ritobegron is combined with Furafylline.
Bucindolol The risk or severity of adverse effects can be increased when Bucindolol is combined with Furafylline.
Tramazoline The risk or severity of adverse effects can be increased when Tramazoline is combined with Furafylline.
Mephedrone The risk or severity of adverse effects can be increased when Mephedrone is combined with Furafylline.
Fenozolone The risk or severity of adverse effects can be increased when Fenozolone is combined with Furafylline.
Methoxyphenamine The risk or severity of adverse effects can be increased when Methoxyphenamine is combined with Furafylline.
Tretoquinol The risk or severity of adverse effects can be increased when Tretoquinol is combined with Furafylline.
Gepefrine The risk or severity of adverse effects can be increased when Gepefrine is combined with Furafylline.
Epanolol The risk or severity of adverse effects can be increased when Epanolol is combined with Furafylline.
Prenalterol The risk or severity of adverse effects can be increased when Prenalterol is combined with Furafylline.
Mefenorex The risk or severity of adverse effects can be increased when Mefenorex is combined with Furafylline.
2,5-Dimethoxy-4-ethylthioamphetamine The risk or severity of adverse effects can be increased when 2,5-Dimethoxy-4-ethylthioamphetamine is combined with Furafylline.
Esmolol The risk or severity of adverse effects can be increased when Esmolol is combined with Furafylline.
Metoprolol The risk or severity of adverse effects can be increased when Metoprolol is combined with Furafylline.
Atenolol The risk or severity of adverse effects can be increased when Atenolol is combined with Furafylline.
Timolol The risk or severity of adverse effects can be increased when Timolol is combined with Furafylline.
Sotalol The risk or severity of adverse effects can be increased when Sotalol is combined with Furafylline.
Bisoprolol The risk or severity of adverse effects can be increased when Bisoprolol is combined with Furafylline.
Alprenolol The risk or severity of adverse effects can be increased when Alprenolol is combined with Furafylline.
Pindolol The risk or severity of adverse effects can be increased when Pindolol is combined with Furafylline.
Bevantolol The risk or severity of adverse effects can be increased when Bevantolol is combined with Furafylline.
Practolol The risk or severity of adverse effects can be increased when Practolol is combined with Furafylline.
Penbutolol The risk or severity of adverse effects can be increased when Penbutolol is combined with Furafylline.

Referensi & Sumber

Artikel (PubMed)
  • PMID: 2378786
    Sesardic D, Boobis AR, Murray BP, Murray S, Segura J, de la Torre R, Davies DS: Furafylline is a potent and selective inhibitor of cytochrome P450IA2 in man. Br J Clin Pharmacol. 1990 Jun;29(6):651-63.

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