Cyclopropane

DB13984

small molecule experimental

Deskripsi

Cyclopropane was initially investigated because it was thought to be the toxic element in ethylene. Instead, it turned out to be an excellent anesthetic with very rapid onset and recovery while maintaining stable hemodynamics. Its use was ultimately limited because it was highly explosive.

Struktur Molekul 2D

Berat 42.081
Wujud solid

Peta Jejaring Molekuler
Legenda: ObatTargetGenEnzim(Panah → menunjukkan arah efek / relasi)TransporterCarrier

Profil Farmakokinetik

Waktu Paruh (Half-Life) -
Volume Distribusi -
Klirens (Clearance) -

Absorpsi

Data absorpsi tidak tersedia.

Metabolisme

Data metabolisme tidak tersedia.

Rute Eliminasi

Data eliminasi belum tersedia.

Interaksi Obat

664 Data
Buprenorphine Cyclopropane may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Doxylamine Doxylamine may increase the central nervous system depressant (CNS depressant) activities of Cyclopropane.
Dronabinol Dronabinol may increase the central nervous system depressant (CNS depressant) activities of Cyclopropane.
Droperidol Droperidol may increase the central nervous system depressant (CNS depressant) activities of Cyclopropane.
Hydrocodone Cyclopropane may increase the central nervous system depressant (CNS depressant) activities of Hydrocodone.
Hydroxyzine Hydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Cyclopropane.
Magnesium sulfate The therapeutic efficacy of Cyclopropane can be increased when used in combination with Magnesium sulfate.
Methotrimeprazine Cyclopropane may increase the central nervous system depressant (CNS depressant) activities of Methotrimeprazine.
Metyrosine Cyclopropane may increase the sedative activities of Metyrosine.
Minocycline Minocycline may increase the central nervous system depressant (CNS depressant) activities of Cyclopropane.
Mirtazapine Cyclopropane may increase the central nervous system depressant (CNS depressant) activities of Mirtazapine.
Nabilone Nabilone may increase the central nervous system depressant (CNS depressant) activities of Cyclopropane.
Orphenadrine Cyclopropane may increase the central nervous system depressant (CNS depressant) activities of Orphenadrine.
Paraldehyde Cyclopropane may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
Perampanel Perampanel may increase the central nervous system depressant (CNS depressant) activities of Cyclopropane.
Pramipexole Cyclopropane may increase the sedative activities of Pramipexole.
Ropinirole Cyclopropane may increase the sedative activities of Ropinirole.
Rotigotine Cyclopropane may increase the sedative activities of Rotigotine.
Rufinamide The risk or severity of adverse effects can be increased when Rufinamide is combined with Cyclopropane.
Sodium oxybate Cyclopropane may increase the central nervous system depressant (CNS depressant) activities of Sodium oxybate.
Suvorexant Cyclopropane may increase the central nervous system depressant (CNS depressant) activities of Suvorexant.
Tapentadol Tapentadol may increase the central nervous system depressant (CNS depressant) activities of Cyclopropane.
Thalidomide Cyclopropane may increase the central nervous system depressant (CNS depressant) activities of Thalidomide.
Zolpidem Cyclopropane may increase the central nervous system depressant (CNS depressant) activities of Zolpidem.
Methadone The risk or severity of adverse effects can be increased when Methadone is combined with Cyclopropane.
Ethanol Cyclopropane may increase the central nervous system depressant (CNS depressant) activities of Ethanol.
Azelastine Cyclopropane may increase the central nervous system depressant (CNS depressant) activities of Azelastine.
Brimonidine Brimonidine may increase the central nervous system depressant (CNS depressant) activities of Cyclopropane.
Fluvoxamine The risk or severity of adverse effects can be increased when Cyclopropane is combined with Fluvoxamine.
Citalopram The risk or severity of adverse effects can be increased when Cyclopropane is combined with Citalopram.
Duloxetine The risk or severity of adverse effects can be increased when Cyclopropane is combined with Duloxetine.
Trazodone The risk or severity of adverse effects can be increased when Cyclopropane is combined with Trazodone.
Paroxetine The risk or severity of adverse effects can be increased when Cyclopropane is combined with Paroxetine.
Sertraline The risk or severity of adverse effects can be increased when Cyclopropane is combined with Sertraline.
Sibutramine The risk or severity of adverse effects can be increased when Cyclopropane is combined with Sibutramine.
Nefazodone The risk or severity of adverse effects can be increased when Cyclopropane is combined with Nefazodone.
Escitalopram The risk or severity of adverse effects can be increased when Cyclopropane is combined with Escitalopram.
Zimelidine The risk or severity of adverse effects can be increased when Cyclopropane is combined with Zimelidine.
Dapoxetine The risk or severity of adverse effects can be increased when Cyclopropane is combined with Dapoxetine.
Milnacipran The risk or severity of adverse effects can be increased when Cyclopropane is combined with Milnacipran.
Desvenlafaxine The risk or severity of adverse effects can be increased when Cyclopropane is combined with Desvenlafaxine.
Seproxetine The risk or severity of adverse effects can be increased when Cyclopropane is combined with Seproxetine.
Indalpine The risk or severity of adverse effects can be increased when Cyclopropane is combined with Indalpine.
Ritanserin The risk or severity of adverse effects can be increased when Cyclopropane is combined with Ritanserin.
Alaproclate The risk or severity of adverse effects can be increased when Cyclopropane is combined with Alaproclate.
Amitriptyline The risk or severity of CNS depression can be increased when Amitriptyline is combined with Cyclopropane.
Cyproheptadine The risk or severity of CNS depression can be increased when Cyproheptadine is combined with Cyclopropane.
Imipramine The risk or severity of CNS depression can be increased when Imipramine is combined with Cyclopropane.
Nortriptyline The risk or severity of CNS depression can be increased when Nortriptyline is combined with Cyclopropane.
Amoxapine The risk or severity of CNS depression can be increased when Amoxapine is combined with Cyclopropane.
Propiomazine The risk or severity of CNS depression can be increased when Propiomazine is combined with Cyclopropane.
Maprotiline The risk or severity of CNS depression can be increased when Maprotiline is combined with Cyclopropane.
Doxepin The risk or severity of CNS depression can be increased when Doxepin is combined with Cyclopropane.
Desipramine The risk or severity of CNS depression can be increased when Desipramine is combined with Cyclopropane.
Pizotifen The risk or severity of CNS depression can be increased when Pizotifen is combined with Cyclopropane.
Dosulepin The risk or severity of CNS depression can be increased when Dosulepin is combined with Cyclopropane.
Zopiclone The risk or severity of adverse effects can be increased when Cyclopropane is combined with Zopiclone.
Botulinum toxin type B The risk or severity of CNS depression can be increased when Botulinum toxin type B is combined with Cyclopropane.
Botulinum toxin type A The risk or severity of CNS depression can be increased when Botulinum toxin type A is combined with Cyclopropane.
Tryptophan The risk or severity of CNS depression can be increased when Tryptophan is combined with Cyclopropane.
Baclofen Baclofen may increase the central nervous system depressant (CNS depressant) activities of Cyclopropane.
Lorazepam The risk or severity of CNS depression can be increased when Lorazepam is combined with Cyclopropane.
Ethchlorvynol The risk or severity of CNS depression can be increased when Ethchlorvynol is combined with Cyclopropane.
Succinylcholine The risk or severity of CNS depression can be increased when Succinylcholine is combined with Cyclopropane.
Reserpine The risk or severity of CNS depression can be increased when Reserpine is combined with Cyclopropane.
Eletriptan The risk or severity of CNS depression can be increased when Eletriptan is combined with Cyclopropane.
Enflurane The risk or severity of CNS depression can be increased when Enflurane is combined with Cyclopropane.
Temazepam The risk or severity of CNS depression can be increased when Temazepam is combined with Cyclopropane.
Reboxetine The risk or severity of CNS depression can be increased when Reboxetine is combined with Cyclopropane.
Butabarbital The risk or severity of CNS depression can be increased when Butabarbital is combined with Cyclopropane.
Butalbital The risk or severity of CNS depression can be increased when Butalbital is combined with Cyclopropane.
Methysergide The risk or severity of CNS depression can be increased when Methysergide is combined with Cyclopropane.
Cabergoline The risk or severity of CNS depression can be increased when Cabergoline is combined with Cyclopropane.
Phenytoin The risk or severity of CNS depression can be increased when Phenytoin is combined with Cyclopropane.
Topiramate The risk or severity of CNS depression can be increased when Topiramate is combined with Cyclopropane.
Clemastine The risk or severity of CNS depression can be increased when Clemastine is combined with Cyclopropane.
Venlafaxine The risk or severity of CNS depression can be increased when Venlafaxine is combined with Cyclopropane.
Etomidate The risk or severity of CNS depression can be increased when Etomidate is combined with Cyclopropane.
Morphine The risk or severity of CNS depression can be increased when Morphine is combined with Cyclopropane.
Talbutal The risk or severity of CNS depression can be increased when Talbutal is combined with Cyclopropane.
Pentobarbital The risk or severity of CNS depression can be increased when Pentobarbital is combined with Cyclopropane.
Valproic acid The risk or severity of CNS depression can be increased when Valproic acid is combined with Cyclopropane.
Zolmitriptan The risk or severity of CNS depression can be increased when Zolmitriptan is combined with Cyclopropane.
Codeine The risk or severity of CNS depression can be increased when Codeine is combined with Cyclopropane.
Dihydroergotamine The risk or severity of CNS depression can be increased when Dihydroergotamine is combined with Cyclopropane.
Tolcapone The risk or severity of CNS depression can be increased when Tolcapone is combined with Cyclopropane.
Hydromorphone The risk or severity of CNS depression can be increased when Hydromorphone is combined with Cyclopropane.
Olanzapine The risk or severity of CNS depression can be increased when Olanzapine is combined with Cyclopropane.
Cetirizine The risk or severity of CNS depression can be increased when Cetirizine is combined with Cyclopropane.
Protriptyline The risk or severity of CNS depression can be increased when Protriptyline is combined with Cyclopropane.
Trimethadione The risk or severity of CNS depression can be increased when Trimethadione is combined with Cyclopropane.
Clobazam The risk or severity of sedation, somnolence, and CNS depression can be increased when Clobazam is combined with Cyclopropane.
Chlorzoxazone The risk or severity of CNS depression can be increased when Chlorzoxazone is combined with Cyclopropane.
Clozapine The risk or severity of CNS depression can be increased when Clozapine is combined with Cyclopropane.
Meprobamate The risk or severity of CNS depression can be increased when Meprobamate is combined with Cyclopropane.
Thiethylperazine The risk or severity of CNS depression can be increased when Thiethylperazine is combined with Cyclopropane.
Palonosetron The risk or severity of CNS depression can be increased when Palonosetron is combined with Cyclopropane.
Sulpiride The risk or severity of CNS depression can be increased when Sulpiride is combined with Cyclopropane.
Alprazolam The risk or severity of CNS depression can be increased when Alprazolam is combined with Cyclopropane.
Dexbrompheniramine The risk or severity of CNS depression can be increased when Dexbrompheniramine is combined with Cyclopropane.

Referensi & Sumber

Artikel (PubMed)
  • PMID: 24421247
    Bokoch MP, Gelb AW: From the journal archives: cyclopropane: induction and recovery with a bang! Can J Anaesth. 2014 Aug;61(8):763-6. doi: 10.1007/s12630-014-0109-x. Epub 2014 Jan 14.

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