WIN 55,212-2 is a chemical described as an aminoalkylindole derivative, which produces effects similar to those of cannabinoids such as tetrahydrocannabinol (THC) but has an entirely different chemical structure. It is a potent cannabinoid receptor agonist that has been found to be a potent analgesic in a rat model of neuropathic pain. It activates p42 and p44 MAP kinase via receptor-mediated signaling.
Fitur visualisasi ini dikembangkan menggunakan pendekatan Graph Theory untuk memetakan hubungan polifarmasi dan molekuler. Entitas (Obat, Target, Gen) direpresentasikan sebagai Simpul (Nodes), sedangkan hubungan biologisnya sebagai Sisi (Edges).
drugbank-id dan name pada skema XML DrugBank.targets/target yang memuat polipeptida sasaran.gene-name dan varian snp-effects.Tata letak grafik menggunakan algoritma Force-Directed Graph (Barnes-Hut). Model fisika ini menerapkan gaya tolak-menolak antar simpul (Gravitasi: -3000) agar tidak tumpang tindih, serta gaya pegas (Spring: 0.04) pada garis penghubung untuk fleksibilitas interaksi.
| Ceritinib | WIN 55212-2 may increase the bradycardic activities of Ceritinib. |
| Ivabradine | WIN 55212-2 may increase the bradycardic activities of Ivabradine. |
| Ruxolitinib | Ruxolitinib may increase the bradycardic activities of WIN 55212-2. |
| Eliglustat | The metabolism of Eliglustat can be decreased when combined with WIN 55212-2. |
| Ibrutinib | The metabolism of Ibrutinib can be decreased when combined with WIN 55212-2. |
| Cilostazol | The metabolism of Cilostazol can be decreased when combined with WIN 55212-2. |
| Colchicine | The metabolism of Colchicine can be decreased when combined with WIN 55212-2. |
| Fentanyl | The risk or severity of adverse effects can be increased when WIN 55212-2 is combined with Fentanyl. |
| Iloperidone | The metabolism of Iloperidone can be decreased when combined with WIN 55212-2. |
| Retapamulin | The metabolism of Retapamulin can be decreased when combined with WIN 55212-2. |
| Tofacitinib | The metabolism of Tofacitinib can be decreased when combined with WIN 55212-2. |
| Vardenafil | The metabolism of Vardenafil can be decreased when combined with WIN 55212-2. |
| Lovastatin | The metabolism of Lovastatin can be decreased when combined with WIN 55212-2. |
| Cimetidine | The serum concentration of WIN 55212-2 can be increased when it is combined with Cimetidine. |
| Clopidogrel | The therapeutic efficacy of Clopidogrel can be decreased when used in combination with WIN 55212-2. |
| Efavirenz | The serum concentration of WIN 55212-2 can be decreased when it is combined with Efavirenz. |
| Melatonin | The therapeutic efficacy of WIN 55212-2 can be decreased when used in combination with Melatonin. |
| Nafcillin | The therapeutic efficacy of WIN 55212-2 can be decreased when used in combination with Nafcillin. |
| Nitroprusside | WIN 55212-2 may increase the hypotensive activities of Nitroprusside. |
| Dantrolene | The risk or severity of hyperkalemia can be increased when Dantrolene is combined with WIN 55212-2. |
| Lithium citrate | The risk or severity of adverse effects can be increased when WIN 55212-2 is combined with Lithium citrate. |
| Lithium hydroxide | The risk or severity of adverse effects can be increased when WIN 55212-2 is combined with Lithium hydroxide. |
| Alfuzosin | The metabolism of Alfuzosin can be decreased when combined with WIN 55212-2. |
| Alprazolam | The metabolism of Alprazolam can be decreased when combined with WIN 55212-2. |
| Cocaine | Cocaine may increase the tachycardic activities of WIN 55212-2. |
| Warfarin | The serum concentration of Warfarin can be increased when it is combined with WIN 55212-2. |
| Acenocoumarol | The serum concentration of Acenocoumarol can be increased when it is combined with WIN 55212-2. |
| (R)-warfarin | The serum concentration of (R)-warfarin can be increased when it is combined with WIN 55212-2. |
| R,S-Warfarin alcohol | The serum concentration of R,S-Warfarin alcohol can be increased when it is combined with WIN 55212-2. |
| S,R-Warfarin alcohol | The serum concentration of S,R-Warfarin alcohol can be increased when it is combined with WIN 55212-2. |
| (S)-Warfarin | The serum concentration of (S)-Warfarin can be increased when it is combined with WIN 55212-2. |
| Midazolam | The serum concentration of Midazolam can be increased when it is combined with WIN 55212-2. |
| Tacrolimus | The serum concentration of Tacrolimus can be increased when it is combined with WIN 55212-2. |
| Atorvastatin | The metabolism of Atorvastatin can be decreased when combined with WIN 55212-2. |
| Boceprevir | The serum concentration of WIN 55212-2 can be increased when it is combined with Boceprevir. |
| Ibutilide | Ibutilide may increase the arrhythmogenic activities of WIN 55212-2. |
| Levosimendan | Levosimendan may increase the arrhythmogenic activities of WIN 55212-2. |
| Procainamide | Procainamide may increase the arrhythmogenic activities of WIN 55212-2. |
| Tocainide | Tocainide may increase the arrhythmogenic activities of WIN 55212-2. |
| Flecainide | Flecainide may increase the arrhythmogenic activities of WIN 55212-2. |
| Encainide | Encainide may increase the arrhythmogenic activities of WIN 55212-2. |
| Ajmaline | Ajmaline may increase the arrhythmogenic activities of WIN 55212-2. |
| Aprindine | Aprindine may increase the arrhythmogenic activities of WIN 55212-2. |
| Azimilide | Azimilide may increase the arrhythmogenic activities of WIN 55212-2. |
| Tedisamil | Tedisamil may increase the arrhythmogenic activities of WIN 55212-2. |
| Vernakalant | Vernakalant may increase the arrhythmogenic activities of WIN 55212-2. |
| Cariporide | Cariporide may increase the arrhythmogenic activities of WIN 55212-2. |
| Sparteine | Sparteine may increase the arrhythmogenic activities of WIN 55212-2. |
| Fasudil | Fasudil may increase the arrhythmogenic activities of WIN 55212-2. |
| Simendan | Simendan may increase the arrhythmogenic activities of WIN 55212-2. |
| Spiradoline | Spiradoline may increase the arrhythmogenic activities of WIN 55212-2. |
| Pilsicainide | Pilsicainide may increase the arrhythmogenic activities of WIN 55212-2. |
| Cicletanine | Cicletanine may increase the arrhythmogenic activities of WIN 55212-2. |
| Cibenzoline | Cibenzoline may increase the arrhythmogenic activities of WIN 55212-2. |
| Nizofenone | Nizofenone may increase the arrhythmogenic activities of WIN 55212-2. |
| Prajmaline | Prajmaline may increase the arrhythmogenic activities of WIN 55212-2. |
| Tiracizine | Tiracizine may increase the arrhythmogenic activities of WIN 55212-2. |
| Ethacizine | Ethacizine may increase the arrhythmogenic activities of WIN 55212-2. |
| Lorajmine | Lorajmine may increase the arrhythmogenic activities of WIN 55212-2. |
| Bunaftine | Bunaftine may increase the arrhythmogenic activities of WIN 55212-2. |
| Lorcainide | Lorcainide may increase the arrhythmogenic activities of WIN 55212-2. |
| Hydroquinine | Hydroquinine may increase the arrhythmogenic activities of WIN 55212-2. |
| Fosfructose | Fosfructose may increase the arrhythmogenic activities of WIN 55212-2. |
| Carteolol | WIN 55212-2 may increase the arrhythmogenic activities of Carteolol. |
| Metipranolol | WIN 55212-2 may increase the arrhythmogenic activities of Metipranolol. |
| Bioallethrin | WIN 55212-2 may increase the arrhythmogenic activities of Bioallethrin. |
| Hydroquinidine | WIN 55212-2 may increase the arrhythmogenic activities of Hydroquinidine. |
| SOR-C13 | WIN 55212-2 may increase the arrhythmogenic activities of SOR-C13. |
| Digoxin | Digoxin may increase the arrhythmogenic activities of WIN 55212-2. |
| Acetyldigitoxin | Acetyldigitoxin may increase the arrhythmogenic activities of WIN 55212-2. |
| Deslanoside | Deslanoside may increase the arrhythmogenic activities of WIN 55212-2. |
| Cymarin | Cymarin may increase the arrhythmogenic activities of WIN 55212-2. |
| Metildigoxin | Metildigoxin may increase the arrhythmogenic activities of WIN 55212-2. |
| Acetyldigoxin | Acetyldigoxin may increase the arrhythmogenic activities of WIN 55212-2. |
| Disopyramide | Disopyramide may increase the arrhythmogenic activities of WIN 55212-2. |
| Hyoscyamine | Hyoscyamine may increase the arrhythmogenic activities of WIN 55212-2. |
| Atropine | Atropine may increase the arrhythmogenic activities of WIN 55212-2. |
| Nicardipine | Nicardipine may increase the arrhythmogenic activities of WIN 55212-2. |
| Trimebutine | Trimebutine may increase the arrhythmogenic activities of WIN 55212-2. |
| Otilonium | Otilonium may increase the arrhythmogenic activities of WIN 55212-2. |
| Niguldipine | Niguldipine may increase the arrhythmogenic activities of WIN 55212-2. |
| Bretylium | Bretylium may increase the arrhythmogenic activities of WIN 55212-2. |
| Isradipine | Isradipine may increase the arrhythmogenic activities of WIN 55212-2. |
| Diltiazem | Diltiazem may increase the arrhythmogenic activities of WIN 55212-2. |
| Amlodipine | Amlodipine may increase the arrhythmogenic activities of WIN 55212-2. |
| Nimodipine | Nimodipine may increase the arrhythmogenic activities of WIN 55212-2. |
| Lercanidipine | Lercanidipine may increase the arrhythmogenic activities of WIN 55212-2. |
| Cinnarizine | Cinnarizine may increase the arrhythmogenic activities of WIN 55212-2. |
| Verapamil | Verapamil may increase the arrhythmogenic activities of WIN 55212-2. |
| Losartan | Losartan may increase the arrhythmogenic activities of WIN 55212-2. |
| Levomenthol | Levomenthol may increase the arrhythmogenic activities of WIN 55212-2. |
| Nitrendipine | Nitrendipine may increase the arrhythmogenic activities of WIN 55212-2. |
| Perhexiline | Perhexiline may increase the arrhythmogenic activities of WIN 55212-2. |
| Bepridil | Bepridil may increase the arrhythmogenic activities of WIN 55212-2. |
| Nimesulide | Nimesulide may increase the arrhythmogenic activities of WIN 55212-2. |
| Prenylamine | Prenylamine may increase the arrhythmogenic activities of WIN 55212-2. |
| Cyclandelate | Cyclandelate may increase the arrhythmogenic activities of WIN 55212-2. |
| Clevidipine | Clevidipine may increase the arrhythmogenic activities of WIN 55212-2. |
| Seletracetam | Seletracetam may increase the arrhythmogenic activities of WIN 55212-2. |
| Nylidrin | Nylidrin may increase the arrhythmogenic activities of WIN 55212-2. |