Demegestone is a progesterone receptor agonist that was previously used to treat luteal insufficiency. It was previously marketed in France as Lutionex, but has since been discontinued.
Fitur visualisasi ini dikembangkan menggunakan pendekatan Graph Theory untuk memetakan hubungan polifarmasi dan molekuler. Entitas (Obat, Target, Gen) direpresentasikan sebagai Simpul (Nodes), sedangkan hubungan biologisnya sebagai Sisi (Edges).
drugbank-id dan name pada skema XML DrugBank.targets/target yang memuat polipeptida sasaran.gene-name dan varian snp-effects.Tata letak grafik menggunakan algoritma Force-Directed Graph (Barnes-Hut). Model fisika ini menerapkan gaya tolak-menolak antar simpul (Gravitasi: -3000) agar tidak tumpang tindih, serta gaya pegas (Spring: 0.04) pada garis penghubung untuk fleksibilitas interaksi.
| Acitretin | The therapeutic efficacy of Demegestone can be decreased when used in combination with Acitretin. |
| Aprepitant | The serum concentration of Demegestone can be decreased when it is combined with Aprepitant. |
| Atazanavir | The serum concentration of Demegestone can be increased when it is combined with Atazanavir. |
| Boceprevir | The serum concentration of Demegestone can be increased when it is combined with Boceprevir. |
| Prucalopride | The serum concentration of Demegestone can be decreased when it is combined with Prucalopride. |
| Sugammadex | The serum concentration of Demegestone can be decreased when it is combined with Sugammadex. |
| Thalidomide | Demegestone may increase the thrombogenic activities of Thalidomide. |
| Ulipristal | The therapeutic efficacy of Demegestone can be decreased when used in combination with Ulipristal. |
| Ursodeoxycholic acid | The therapeutic efficacy of Ursodeoxycholic acid can be decreased when used in combination with Demegestone. |
| Glycochenodeoxycholic Acid | The therapeutic efficacy of Glycochenodeoxycholic Acid can be decreased when used in combination with Demegestone. |
| Cholic Acid | The therapeutic efficacy of Cholic Acid can be decreased when used in combination with Demegestone. |
| Glycocholic acid | The therapeutic efficacy of Glycocholic acid can be decreased when used in combination with Demegestone. |
| Deoxycholic acid | The therapeutic efficacy of Deoxycholic acid can be decreased when used in combination with Demegestone. |
| Taurocholic acid | The therapeutic efficacy of Taurocholic acid can be decreased when used in combination with Demegestone. |
| Obeticholic acid | The therapeutic efficacy of Obeticholic acid can be decreased when used in combination with Demegestone. |
| Tauroursodeoxycholic acid | The therapeutic efficacy of Tauroursodeoxycholic acid can be decreased when used in combination with Demegestone. |
| Bamet-UD2 | The therapeutic efficacy of Bamet-UD2 can be decreased when used in combination with Demegestone. |
| cis-Diamminechlorocholylglycinateplatinum(II) | The therapeutic efficacy of cis-Diamminechlorocholylglycinateplatinum(II) can be decreased when used in combination with Demegestone. |
| Dehydrocholic acid | The therapeutic efficacy of Dehydrocholic acid can be decreased when used in combination with Demegestone. |
| Hyodeoxycholic Acid | The therapeutic efficacy of Hyodeoxycholic Acid can be decreased when used in combination with Demegestone. |
| Aramchol | The therapeutic efficacy of Aramchol can be decreased when used in combination with Demegestone. |
| Ox bile extract | The therapeutic efficacy of Ox bile extract can be decreased when used in combination with Demegestone. |
| Chenodeoxycholic acid | The therapeutic efficacy of Chenodeoxycholic acid can be decreased when used in combination with Demegestone. |
| Taurochenodeoxycholic acid | The therapeutic efficacy of Taurochenodeoxycholic acid can be decreased when used in combination with Demegestone. |
| Tranexamic acid | Demegestone may increase the thrombogenic activities of Tranexamic acid. |
| Clobazam | The serum concentration of Demegestone can be decreased when it is combined with Clobazam. |
| Colestipol | Colestipol can cause a decrease in the absorption of Demegestone resulting in a reduced serum concentration and potentially a decrease in efficacy. |
| Sevelamer | Sevelamer can cause a decrease in the absorption of Demegestone resulting in a reduced serum concentration and potentially a decrease in efficacy. |
| Colesevelam | Colesevelam can cause a decrease in the absorption of Demegestone resulting in a reduced serum concentration and potentially a decrease in efficacy. |
| Cholestyramine | Cholestyramine can cause a decrease in the absorption of Demegestone resulting in a reduced serum concentration and potentially a decrease in efficacy. |
| Griseofulvin | The metabolism of Demegestone can be increased when combined with Griseofulvin. |
| Tixocortol | The serum concentration of Tixocortol can be increased when it is combined with Demegestone. |
| Fluocortin | The serum concentration of Fluocortin can be increased when it is combined with Demegestone. |
| Fluperolone | The serum concentration of Fluperolone can be increased when it is combined with Demegestone. |
| Fluclorolone | The serum concentration of Fluclorolone can be increased when it is combined with Demegestone. |
| Flunisolide | The serum concentration of Flunisolide can be increased when it is combined with Demegestone. |
| Beclomethasone dipropionate | The serum concentration of Beclomethasone dipropionate can be increased when it is combined with Demegestone. |
| Betamethasone | The serum concentration of Betamethasone can be increased when it is combined with Demegestone. |
| Fluocinolone acetonide | The serum concentration of Fluocinolone acetonide can be increased when it is combined with Demegestone. |
| Triamcinolone | The serum concentration of Triamcinolone can be increased when it is combined with Demegestone. |
| Prednisone | The serum concentration of Prednisone can be increased when it is combined with Demegestone. |
| Hydrocortisone | The serum concentration of Hydrocortisone can be increased when it is combined with Demegestone. |
| Prednisolone | The serum concentration of Prednisolone can be increased when it is combined with Demegestone. |
| Methylprednisolone | The serum concentration of Methylprednisolone can be increased when it is combined with Demegestone. |
| Corticotropin | The serum concentration of Corticotropin can be increased when it is combined with Demegestone. |
| Cortisone acetate | The serum concentration of Cortisone acetate can be increased when it is combined with Demegestone. |
| Fluprednidene | The serum concentration of Fluprednidene can be increased when it is combined with Demegestone. |
| Meprednisone | The serum concentration of Meprednisone can be increased when it is combined with Demegestone. |
| Dexamethasone isonicotinate | The serum concentration of Dexamethasone isonicotinate can be increased when it is combined with Demegestone. |
| Deflazacort | The serum concentration of Deflazacort can be increased when it is combined with Demegestone. |
| Cortivazol | The serum concentration of Cortivazol can be increased when it is combined with Demegestone. |
| Prednylidene | The serum concentration of Prednylidene can be increased when it is combined with Demegestone. |
| Cloprednol | The serum concentration of Cloprednol can be increased when it is combined with Demegestone. |
| Mometasone furoate | The serum concentration of Mometasone furoate can be increased when it is combined with Demegestone. |
| Hydrocortisone acetate | The serum concentration of Hydrocortisone acetate can be increased when it is combined with Demegestone. |
| Hydrocortisone succinate | The serum concentration of Hydrocortisone succinate can be increased when it is combined with Demegestone. |
| Prednisolone phosphate | The serum concentration of Prednisolone phosphate can be increased when it is combined with Demegestone. |
| Prednisolone hemisuccinate | The serum concentration of Prednisolone hemisuccinate can be increased when it is combined with Demegestone. |
| Methylprednisolone hemisuccinate | The serum concentration of Methylprednisolone hemisuccinate can be increased when it is combined with Demegestone. |
| Prednisone acetate | The serum concentration of Prednisone acetate can be increased when it is combined with Demegestone. |
| Clocortolone acetate | The serum concentration of Clocortolone acetate can be increased when it is combined with Demegestone. |
| Melengestrol acetate | The serum concentration of Melengestrol acetate can be increased when it is combined with Demegestone. |
| Betamethasone phosphate | The serum concentration of Betamethasone phosphate can be increased when it is combined with Demegestone. |
| Cortisone | The serum concentration of Cortisone can be increased when it is combined with Demegestone. |
| Fluticasone propionate | The serum concentration of Fluticasone propionate can be increased when it is combined with Demegestone. |
| Fludrocortisone | The serum concentration of Fludrocortisone can be increased when it is combined with Demegestone. |
| Trilostane | The serum concentration of Trilostane can be increased when it is combined with Demegestone. |
| Budesonide | The serum concentration of Budesonide can be increased when it is combined with Demegestone. |
| Dexamethasone | The serum concentration of Dexamethasone can be increased when it is combined with Demegestone. |
| Paramethasone | The serum concentration of Paramethasone can be increased when it is combined with Demegestone. |
| Ciclesonide | The serum concentration of Ciclesonide can be increased when it is combined with Demegestone. |
| Aldosterone | The serum concentration of Aldosterone can be increased when it is combined with Demegestone. |
| Fluticasone furoate | The serum concentration of Fluticasone furoate can be increased when it is combined with Demegestone. |
| Fluprednisolone | The serum concentration of Fluprednisolone can be increased when it is combined with Demegestone. |
| Melengestrol | The serum concentration of Melengestrol can be increased when it is combined with Demegestone. |
| Fluticasone | The serum concentration of Fluticasone can be increased when it is combined with Demegestone. |
| Hydrocortisone cypionate | The serum concentration of Hydrocortisone cypionate can be increased when it is combined with Demegestone. |
| Clobetasol propionate | The serum concentration of Clobetasol propionate can be increased when it is combined with Demegestone. |
| Fluocinonide | The serum concentration of Fluocinonide can be increased when it is combined with Demegestone. |
| Hydrocortisone butyrate | The serum concentration of Hydrocortisone butyrate can be increased when it is combined with Demegestone. |
| Desoximetasone | The serum concentration of Desoximetasone can be increased when it is combined with Demegestone. |
| Mometasone | The serum concentration of Mometasone can be increased when it is combined with Demegestone. |
| Fluocortolone | The serum concentration of Fluocortolone can be increased when it is combined with Demegestone. |
| Prednisolone acetate | The serum concentration of Prednisolone acetate can be increased when it is combined with Demegestone. |
| Fluorometholone | The serum concentration of Fluorometholone can be increased when it is combined with Demegestone. |
| Difluocortolone | The serum concentration of Difluocortolone can be increased when it is combined with Demegestone. |
| Flumethasone | The serum concentration of Flumethasone can be increased when it is combined with Demegestone. |
| Methylprednisolone aceponate | The serum concentration of Methylprednisolone aceponate can be increased when it is combined with Demegestone. |
| Vitamin A | The therapeutic efficacy of Demegestone can be decreased when used in combination with Vitamin A. |
| Bexarotene | The therapeutic efficacy of Demegestone can be decreased when used in combination with Bexarotene. |
| Alitretinoin | The therapeutic efficacy of Demegestone can be decreased when used in combination with Alitretinoin. |
| Tretinoin | The therapeutic efficacy of Demegestone can be decreased when used in combination with Tretinoin. |
| Tazarotene | The therapeutic efficacy of Demegestone can be decreased when used in combination with Tazarotene. |
| Etretinate | The therapeutic efficacy of Demegestone can be decreased when used in combination with Etretinate. |
| Isotretinoin | The therapeutic efficacy of Demegestone can be decreased when used in combination with Isotretinoin. |
| 4-Oxoretinol | The therapeutic efficacy of Demegestone can be decreased when used in combination with 4-Oxoretinol. |
| Fenretinide | The therapeutic efficacy of Demegestone can be decreased when used in combination with Fenretinide. |
| Ro 12-7310 | The therapeutic efficacy of Demegestone can be decreased when used in combination with Ro 12-7310. |
| Zuretinol acetate | The therapeutic efficacy of Demegestone can be decreased when used in combination with Zuretinol acetate. |
| Motretinide | The therapeutic efficacy of Demegestone can be decreased when used in combination with Motretinide. |