Clopamide

DB13792

small molecule experimental

Deskripsi

Clopamide is an oral diuretic agent with antihypertensive activity. Like thiazide diuretics, it has an aromatic sulfonamide base but with no double-ring structure.

Struktur Molekul 2D

Berat 345.84
Wujud -

Peta Jejaring Molekuler
Legenda: ObatTargetGenEnzim(Panah → menunjukkan arah efek / relasi)TransporterCarrier

Profil Farmakokinetik

Waktu Paruh (Half-Life) -
Volume Distribusi -
Klirens (Clearance) -

Absorpsi

Data absorpsi tidak tersedia.

Metabolisme

Data metabolisme tidak tersedia.

Rute Eliminasi

Data eliminasi belum tersedia.

Interaksi Obat

715 Data
Nicotine The risk or severity of adverse effects can be increased when Clopamide is combined with Nicotine.
Mecamylamine The risk or severity of adverse effects can be increased when Clopamide is combined with Mecamylamine.
Pentolinium The risk or severity of adverse effects can be increased when Clopamide is combined with Pentolinium.
Trimethaphan The risk or severity of adverse effects can be increased when Clopamide is combined with Trimethaphan.
Hexamethonium The risk or severity of adverse effects can be increased when Clopamide is combined with Hexamethonium.
Cyclopentamine The risk or severity of adverse effects can be increased when Clopamide is combined with Cyclopentamine.
Methotrexate The protein binding of Methotrexate can be increased when combined with Clopamide.
Dexketoprofen The risk or severity of adverse effects can be increased when Dexketoprofen is combined with Clopamide.
Ketoprofen The risk or severity of adverse effects can be increased when Ketoprofen is combined with Clopamide.
Cyclosporine The risk or severity of renal failure can be increased when Clopamide is combined with Cyclosporine.
Sodium phosphate, monobasic Clopamide may increase the nephrotoxic activities of Sodium phosphate, monobasic.
Acemetacin The therapeutic efficacy of Clopamide can be decreased when used in combination with Acemetacin.
Lactulose The risk or severity of dehydration can be increased when Clopamide is combined with Lactulose.
Magnesium sulfate The risk or severity of dehydration can be increased when Clopamide is combined with Magnesium sulfate.
Mannitol The risk or severity of dehydration can be increased when Clopamide is combined with Mannitol.
Lubiprostone The risk or severity of dehydration can be increased when Clopamide is combined with Lubiprostone.
Tegaserod The risk or severity of dehydration can be increased when Clopamide is combined with Tegaserod.
Magnesium oxide The risk or severity of dehydration can be increased when Clopamide is combined with Magnesium oxide.
Magnesium cation The risk or severity of dehydration can be increased when Clopamide is combined with Magnesium cation.
Sorbitol The risk or severity of dehydration can be increased when Clopamide is combined with Sorbitol.
Dantron The risk or severity of dehydration can be increased when Clopamide is combined with Dantron.
Oxyphenisatin The risk or severity of dehydration can be increased when Clopamide is combined with Oxyphenisatin.
Phenolphthalein The risk or severity of dehydration can be increased when Clopamide is combined with Phenolphthalein.
Prucalopride The risk or severity of dehydration can be increased when Clopamide is combined with Prucalopride.
Emodin The risk or severity of dehydration can be increased when Clopamide is combined with Emodin.
Linaclotide The risk or severity of dehydration can be increased when Clopamide is combined with Linaclotide.
Bisacodyl The risk or severity of dehydration can be increased when Clopamide is combined with Bisacodyl.
Magnesium hydroxide The risk or severity of dehydration can be increased when Clopamide is combined with Magnesium hydroxide.
Bisoxatin The risk or severity of dehydration can be increased when Clopamide is combined with Bisoxatin.
Picosulfuric acid The risk or severity of dehydration can be increased when Clopamide is combined with Picosulfuric acid.
Magnesium trisilicate The risk or severity of dehydration can be increased when Clopamide is combined with Magnesium trisilicate.
Polyethylene glycol The risk or severity of dehydration can be increased when Clopamide is combined with Polyethylene glycol.
Polycarbophil The risk or severity of dehydration can be increased when Clopamide is combined with Polycarbophil.
Magnesium acetate tetrahydrate The risk or severity of dehydration can be increased when Clopamide is combined with Magnesium acetate tetrahydrate.
Monopotassium phosphate The risk or severity of dehydration can be increased when Clopamide is combined with Monopotassium phosphate.
Dipotassium phosphate The risk or severity of dehydration can be increased when Clopamide is combined with Dipotassium phosphate.
Glycerin The risk or severity of dehydration can be increased when Clopamide is combined with Glycerin.
Sodium sulfate The risk or severity of dehydration can be increased when Clopamide is combined with Sodium sulfate.
Magnesium carbonate The risk or severity of dehydration can be increased when Clopamide is combined with Magnesium carbonate.
Potassium lactate The risk or severity of dehydration can be increased when Clopamide is combined with Potassium lactate.
Sodium fluorophosphate The risk or severity of dehydration can be increased when Clopamide is combined with Sodium fluorophosphate.
Mineral oil The risk or severity of dehydration can be increased when Clopamide is combined with Mineral oil.
Carboxymethylcellulose The risk or severity of dehydration can be increased when Clopamide is combined with Carboxymethylcellulose.
Docusate The risk or severity of dehydration can be increased when Clopamide is combined with Docusate.
Plantago seed The risk or severity of dehydration can be increased when Clopamide is combined with Plantago seed.
Magnesium citrate The risk or severity of dehydration can be increased when Clopamide is combined with Magnesium citrate.
Castor oil The risk or severity of dehydration can be increased when Clopamide is combined with Castor oil.
Magnesium glycinate The risk or severity of dehydration can be increased when Clopamide is combined with Magnesium glycinate.
Methylcellulose The risk or severity of dehydration can be increased when Clopamide is combined with Methylcellulose.
Sennosides The risk or severity of dehydration can be increased when Clopamide is combined with Sennosides.
Lactitol The risk or severity of dehydration can be increased when Clopamide is combined with Lactitol.
Plecanatide The risk or severity of dehydration can be increased when Clopamide is combined with Plecanatide.
Gluconic Acid The risk or severity of dehydration can be increased when Clopamide is combined with Gluconic Acid.
Magnesium peroxide The risk or severity of dehydration can be increased when Clopamide is combined with Magnesium peroxide.
Pentaerithrityl The risk or severity of dehydration can be increased when Clopamide is combined with Pentaerithrityl.
Sodium tartrate The risk or severity of dehydration can be increased when Clopamide is combined with Sodium tartrate.
Magnesium acetate The risk or severity of dehydration can be increased when Clopamide is combined with Magnesium acetate.
Deacetylbisacodyl The risk or severity of dehydration can be increased when Clopamide is combined with Deacetylbisacodyl.
Sodium ascorbate The risk or severity of dehydration can be increased when Clopamide is combined with Sodium ascorbate.
Potassium sulfate The risk or severity of dehydration can be increased when Clopamide is combined with Potassium sulfate.
Sodium phosphate, dibasic The risk or severity of dehydration can be increased when Clopamide is combined with Sodium phosphate, dibasic.
Sodium phosphate, monobasic, unspecified form The risk or severity of dehydration can be increased when Clopamide is combined with Sodium phosphate, monobasic, unspecified form.
Sodium phosphate, dibasic, unspecified form The risk or severity of dehydration can be increased when Clopamide is combined with Sodium phosphate, dibasic, unspecified form.
Sodium cation The risk or severity of dehydration can be increased when Clopamide is combined with Sodium cation.
Plantago ovata seed The risk or severity of dehydration can be increased when Clopamide is combined with Plantago ovata seed.
Oxyphenisatin acetate The risk or severity of dehydration can be increased when Clopamide is combined with Oxyphenisatin acetate.
Calcium polycarbophil The risk or severity of dehydration can be increased when Clopamide is combined with Calcium polycarbophil.
Konjac mannan The risk or severity of dehydration can be increased when Clopamide is combined with Konjac mannan.
Alloin The risk or severity of dehydration can be increased when Clopamide is combined with Alloin.
Frangula purshiana bark The risk or severity of dehydration can be increased when Clopamide is combined with Frangula purshiana bark.
Dehydrocholic acid The risk or severity of dehydration can be increased when Clopamide is combined with Dehydrocholic acid.
Sulfate ion The risk or severity of dehydration can be increased when Clopamide is combined with Sulfate ion.
Insulin human The risk or severity of hypoglycemia can be increased when Clopamide is combined with Insulin human.
Insulin lispro The risk or severity of hypoglycemia can be increased when Clopamide is combined with Insulin lispro.
Insulin glargine The risk or severity of hypoglycemia can be increased when Clopamide is combined with Insulin glargine.
Insulin pork The risk or severity of hypoglycemia can be increased when Clopamide is combined with Insulin pork.
Troglitazone The therapeutic efficacy of Troglitazone can be increased when used in combination with Clopamide.
Glimepiride The therapeutic efficacy of Glimepiride can be increased when used in combination with Clopamide.
Sulfisoxazole The therapeutic efficacy of Sulfisoxazole can be increased when used in combination with Clopamide.
Disopyramide The therapeutic efficacy of Disopyramide can be increased when used in combination with Clopamide.
Acarbose The therapeutic efficacy of Acarbose can be increased when used in combination with Clopamide.
Metformin The therapeutic efficacy of Metformin can be increased when used in combination with Clopamide.
Sulfadiazine The therapeutic efficacy of Sulfadiazine can be increased when used in combination with Clopamide.
Rosiglitazone The therapeutic efficacy of Rosiglitazone can be increased when used in combination with Clopamide.
Acetohexamide The therapeutic efficacy of Acetohexamide can be increased when used in combination with Clopamide.
Quinine The therapeutic efficacy of Quinine can be increased when used in combination with Clopamide.
Miglitol The therapeutic efficacy of Miglitol can be increased when used in combination with Clopamide.
Chlorpropamide The therapeutic efficacy of Chlorpropamide can be increased when used in combination with Clopamide.
Nateglinide The therapeutic efficacy of Nateglinide can be increased when used in combination with Clopamide.
Pentamidine The therapeutic efficacy of Pentamidine can be increased when used in combination with Clopamide.
Mifepristone The therapeutic efficacy of Mifepristone can be increased when used in combination with Clopamide.
Tolazamide The therapeutic efficacy of Tolazamide can be increased when used in combination with Clopamide.
Repaglinide The therapeutic efficacy of Repaglinide can be increased when used in combination with Clopamide.
Phenformin The therapeutic efficacy of Phenformin can be increased when used in combination with Clopamide.
Sulfamethoxazole The therapeutic efficacy of Sulfamethoxazole can be increased when used in combination with Clopamide.
Glyburide The therapeutic efficacy of Glyburide can be increased when used in combination with Clopamide.
Glipizide The therapeutic efficacy of Glipizide can be increased when used in combination with Clopamide.
Gliclazide The therapeutic efficacy of Gliclazide can be increased when used in combination with Clopamide.
Tolbutamide The therapeutic efficacy of Tolbutamide can be increased when used in combination with Clopamide.
Pioglitazone The therapeutic efficacy of Pioglitazone can be increased when used in combination with Clopamide.

Referensi & Sumber

Artikel (PubMed)
  • PMID: 3621784
    McNeil JJ, Conway EL, Drummer OH, Howes LG, Christophidis N, Louis WJ: Clopamide: plasma concentrations and diuretic effect in humans. Clin Pharmacol Ther. 1987 Sep;42(3):299-304.

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