Xamoterol

DB13781

small molecule approved

Deskripsi

Xamoterol is a ?1-adrenoceptor partial agonist that has shown to improve systolic and diastolic function in studies with heart failure patients. It modulates the sympathetic control of the heart but has no agonist action on ?2-adrenoceptors.

Struktur Molekul 2D

Berat 339.392
Wujud -

Peta Jejaring Molekuler
Legenda: ObatTargetGenEnzim(Panah → menunjukkan arah efek / relasi)TransporterCarrier

Profil Farmakokinetik

Waktu Paruh (Half-Life) -
Volume Distribusi -
Klirens (Clearance) -

Absorpsi

Data absorpsi tidak tersedia.

Metabolisme

Data metabolisme tidak tersedia.

Rute Eliminasi

Data eliminasi belum tersedia.

Interaksi Obat

668 Data
Valsartan Xamoterol may decrease the antihypertensive activities of Valsartan.
Ramipril Xamoterol may decrease the antihypertensive activities of Ramipril.
Reserpine Xamoterol may decrease the antihypertensive activities of Reserpine.
Remikiren Xamoterol may decrease the antihypertensive activities of Remikiren.
Torasemide Xamoterol may decrease the antihypertensive activities of Torasemide.
Isradipine Xamoterol may decrease the antihypertensive activities of Isradipine.
Olmesartan Xamoterol may decrease the antihypertensive activities of Olmesartan.
Chlorthalidone Xamoterol may decrease the antihypertensive activities of Chlorthalidone.
Nitroprusside Xamoterol may decrease the antihypertensive activities of Nitroprusside.
Diltiazem Xamoterol may decrease the antihypertensive activities of Diltiazem.
Minoxidil Xamoterol may decrease the antihypertensive activities of Minoxidil.
Treprostinil Xamoterol may decrease the antihypertensive activities of Treprostinil.
Amlodipine Xamoterol may decrease the antihypertensive activities of Amlodipine.
Nimodipine Xamoterol may decrease the antihypertensive activities of Nimodipine.
Nisoldipine Xamoterol may decrease the antihypertensive activities of Nisoldipine.
Bendroflumethiazide Xamoterol may decrease the antihypertensive activities of Bendroflumethiazide.
Fosinopril Xamoterol may decrease the antihypertensive activities of Fosinopril.
Trandolapril Xamoterol may decrease the antihypertensive activities of Trandolapril.
Metolazone Xamoterol may decrease the antihypertensive activities of Metolazone.
Lercanidipine Xamoterol may decrease the antihypertensive activities of Lercanidipine.
Benazepril Xamoterol may decrease the antihypertensive activities of Benazepril.
Bosentan Xamoterol may decrease the antihypertensive activities of Bosentan.
Enalapril Xamoterol may decrease the antihypertensive activities of Enalapril.
Cyclothiazide Xamoterol may decrease the antihypertensive activities of Cyclothiazide.
Candoxatril Xamoterol may decrease the antihypertensive activities of Candoxatril.
Mecamylamine Xamoterol may decrease the antihypertensive activities of Mecamylamine.
Losartan Xamoterol may decrease the antihypertensive activities of Losartan.
Moexipril Xamoterol may decrease the antihypertensive activities of Moexipril.
Eplerenone Xamoterol may decrease the antihypertensive activities of Eplerenone.
Lisinopril Xamoterol may decrease the antihypertensive activities of Lisinopril.
Nitroglycerin Xamoterol may decrease the antihypertensive activities of Nitroglycerin.
Metyrosine Xamoterol may decrease the antihypertensive activities of Metyrosine.
Hydroflumethiazide Xamoterol may decrease the antihypertensive activities of Hydroflumethiazide.
Cryptenamine Xamoterol may decrease the antihypertensive activities of Cryptenamine.
Perindopril Xamoterol may decrease the antihypertensive activities of Perindopril.
Candesartan cilexetil Xamoterol may decrease the antihypertensive activities of Candesartan cilexetil.
Fenoldopam Xamoterol may decrease the antihypertensive activities of Fenoldopam.
Indapamide Xamoterol may decrease the antihypertensive activities of Indapamide.
Tadalafil Xamoterol may decrease the antihypertensive activities of Tadalafil.
Eprosartan Xamoterol may decrease the antihypertensive activities of Eprosartan.
Chlorothiazide Xamoterol may decrease the antihypertensive activities of Chlorothiazide.
Quinapril Xamoterol may decrease the antihypertensive activities of Quinapril.
Telmisartan Xamoterol may decrease the antihypertensive activities of Telmisartan.
Methyldopa Xamoterol may decrease the antihypertensive activities of Methyldopa.
Hydrochlorothiazide Xamoterol may decrease the antihypertensive activities of Hydrochlorothiazide.
Trichlormethiazide Xamoterol may decrease the antihypertensive activities of Trichlormethiazide.
Irbesartan Xamoterol may decrease the antihypertensive activities of Irbesartan.
Nitrendipine Xamoterol may decrease the antihypertensive activities of Nitrendipine.
Deserpidine Xamoterol may decrease the antihypertensive activities of Deserpidine.
Pentolinium Xamoterol may decrease the antihypertensive activities of Pentolinium.
Trimethaphan Xamoterol may decrease the antihypertensive activities of Trimethaphan.
Diazoxide Xamoterol may decrease the antihypertensive activities of Diazoxide.
Captopril Xamoterol may decrease the antihypertensive activities of Captopril.
Epoprostenol Xamoterol may decrease the antihypertensive activities of Epoprostenol.
Bepridil Xamoterol may decrease the antihypertensive activities of Bepridil.
Hydralazine Xamoterol may decrease the antihypertensive activities of Hydralazine.
Polythiazide Xamoterol may decrease the antihypertensive activities of Polythiazide.
Cilazapril Xamoterol may decrease the antihypertensive activities of Cilazapril.
Saprisartan Xamoterol may decrease the antihypertensive activities of Saprisartan.
Spirapril Xamoterol may decrease the antihypertensive activities of Spirapril.
Mibefradil Xamoterol may decrease the antihypertensive activities of Mibefradil.
Tienilic acid Xamoterol may decrease the antihypertensive activities of Tienilic acid.
Debrisoquine Xamoterol may decrease the antihypertensive activities of Debrisoquine.
Sitaxentan Xamoterol may decrease the antihypertensive activities of Sitaxentan.
Ambrisentan Xamoterol may decrease the antihypertensive activities of Ambrisentan.
Diethylnorspermine Xamoterol may decrease the antihypertensive activities of Diethylnorspermine.
Nilvadipine Xamoterol may decrease the antihypertensive activities of Nilvadipine.
Pinacidil Xamoterol may decrease the antihypertensive activities of Pinacidil.
Temocapril Xamoterol may decrease the antihypertensive activities of Temocapril.
Riociguat Xamoterol may decrease the antihypertensive activities of Riociguat.
Macitentan Xamoterol may decrease the antihypertensive activities of Macitentan.
Hexamethonium Xamoterol may decrease the antihypertensive activities of Hexamethonium.
Aliskiren Xamoterol may decrease the antihypertensive activities of Aliskiren.
Nicorandil Xamoterol may decrease the antihypertensive activities of Nicorandil.
Efonidipine Xamoterol may decrease the antihypertensive activities of Efonidipine.
Lacidipine Xamoterol may decrease the antihypertensive activities of Lacidipine.
Manidipine Xamoterol may decrease the antihypertensive activities of Manidipine.
Rauwolfia serpentina root Xamoterol may decrease the antihypertensive activities of Rauwolfia serpentina root.
Enalaprilat Xamoterol may decrease the antihypertensive activities of Enalaprilat.
Selexipag Xamoterol may decrease the antihypertensive activities of Selexipag.
Angiotensin 1-7 Xamoterol may decrease the antihypertensive activities of Angiotensin 1-7.
Imidapril Xamoterol may decrease the antihypertensive activities of Imidapril.
BQ-123 Xamoterol may decrease the antihypertensive activities of BQ-123.
Tetrahydropalmatine Xamoterol may decrease the antihypertensive activities of Tetrahydropalmatine.
Cicletanine Xamoterol may decrease the antihypertensive activities of Cicletanine.
Dihydralazine Xamoterol may decrease the antihypertensive activities of Dihydralazine.
Zofenopril Xamoterol may decrease the antihypertensive activities of Zofenopril.
Guanoxan Xamoterol may decrease the antihypertensive activities of Guanoxan.
Delapril Xamoterol may decrease the antihypertensive activities of Delapril.
Vincamine Xamoterol may decrease the antihypertensive activities of Vincamine.
Linsidomine Xamoterol may decrease the antihypertensive activities of Linsidomine.
Guanoxabenz Xamoterol may decrease the antihypertensive activities of Guanoxabenz.
Tolonidine Xamoterol may decrease the antihypertensive activities of Tolonidine.
Endralazine Xamoterol may decrease the antihypertensive activities of Endralazine.
Cadralazine Xamoterol may decrease the antihypertensive activities of Cadralazine.
Cyclopenthiazide Xamoterol may decrease the antihypertensive activities of Cyclopenthiazide.
Bietaserpine Xamoterol may decrease the antihypertensive activities of Bietaserpine.
Guanazodine Xamoterol may decrease the antihypertensive activities of Guanazodine.
Methoserpidine Xamoterol may decrease the antihypertensive activities of Methoserpidine.
Guanoclor Xamoterol may decrease the antihypertensive activities of Guanoclor.

Target Protein

Beta-3 adrenergic receptor ADRB3
Beta-1 adrenergic receptor ADRB1

Referensi & Sumber

Artikel (PubMed)
  • PMID: 2572252
    Snow HM: The pharmacology of xamoterol: a basis for modulation of the autonomic control of the heart. Br J Clin Pharmacol. 1989;28 Suppl 1:3S-13S.
  • PMID: 2572251
    Marlow HF: Xamoterol, a beta 1-adrenoceptor partial agonist: review of the clinical efficacy in heart failure. Br J Clin Pharmacol. 1989;28 Suppl 1:23S-30S.

Contoh Produk & Brand

Produk: 0 • International brands: 1
International Brands
  • Corwin

Sekuens Gen/Protein (FASTA)

Sekuens dimuat saat dibutuhkan agar halaman tetap ringan.
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