Cyclopenthiazide is a thiazide diuretic with antihypertensive properties. In a double blind, randomized crossover study, cyclopenthiazide was effective in reducing diastolic blood pressure in mildly hypertensive non-insulin dependent diabetic patients A27180. It is a positive allosteric modulator at AMPA-A receptors T28.
Fitur visualisasi ini dikembangkan menggunakan pendekatan Graph Theory untuk memetakan hubungan polifarmasi dan molekuler. Entitas (Obat, Target, Gen) direpresentasikan sebagai Simpul (Nodes), sedangkan hubungan biologisnya sebagai Sisi (Edges).
drugbank-id dan name pada skema XML DrugBank.targets/target yang memuat polipeptida sasaran.gene-name dan varian snp-effects.Tata letak grafik menggunakan algoritma Force-Directed Graph (Barnes-Hut). Model fisika ini menerapkan gaya tolak-menolak antar simpul (Gravitasi: -3000) agar tidak tumpang tindih, serta gaya pegas (Spring: 0.04) pada garis penghubung untuk fleksibilitas interaksi.
| Alfuzosin | Alfuzosin may increase the hypotensive activities of Cyclopenthiazide. |
| Amifostine | Cyclopenthiazide may increase the hypotensive activities of Amifostine. |
| Diazoxide | Diazoxide may increase the hypotensive activities of Cyclopenthiazide. |
| Forasartan | Cyclopenthiazide may increase the hypotensive and Electrolyte Disturbance activities of Forasartan. |
| Tasosartan | Cyclopenthiazide may increase the hypotensive and Electrolyte Disturbance activities of Tasosartan. |
| Saralasin | Cyclopenthiazide may increase the hypotensive and Electrolyte Disturbance activities of Saralasin. |
| Fimasartan | Cyclopenthiazide may increase the hypotensive and Electrolyte Disturbance activities of Fimasartan. |
| Methylphenidate | Methylphenidate may decrease the antihypertensive activities of Cyclopenthiazide. |
| Dexmethylphenidate | Dexmethylphenidate may decrease the antihypertensive activities of Cyclopenthiazide. |
| Obinutuzumab | Cyclopenthiazide may increase the hypotensive activities of Obinutuzumab. |
| Pentoxifylline | Pentoxifylline may increase the hypotensive activities of Cyclopenthiazide. |
| Rituximab | Cyclopenthiazide may increase the hypotensive activities of Rituximab. |
| Phentermine | Phentermine may decrease the antihypertensive activities of Cyclopenthiazide. |
| Midodrine | Midodrine may decrease the antihypertensive activities of Cyclopenthiazide. |
| Eletriptan | Eletriptan may decrease the antihypertensive activities of Cyclopenthiazide. |
| Methysergide | Methysergide may decrease the antihypertensive activities of Cyclopenthiazide. |
| Cabergoline | Cabergoline may decrease the antihypertensive activities of Cyclopenthiazide. |
| Zolmitriptan | Zolmitriptan may decrease the antihypertensive activities of Cyclopenthiazide. |
| Dihydroergotamine | Dihydroergotamine may decrease the antihypertensive activities of Cyclopenthiazide. |
| Protriptyline | Protriptyline may decrease the antihypertensive activities of Cyclopenthiazide. |
| Methylergometrine | Methylergometrine may decrease the antihypertensive activities of Cyclopenthiazide. |
| Mirtazapine | Mirtazapine may decrease the antihypertensive activities of Cyclopenthiazide. |
| Phenylephrine | Phenylephrine may decrease the antihypertensive activities of Cyclopenthiazide. |
| Droperidol | Droperidol may decrease the antihypertensive activities of Cyclopenthiazide. |
| Doxapram | Doxapram may decrease the antihypertensive activities of Cyclopenthiazide. |
| Lisuride | Lisuride may decrease the antihypertensive activities of Cyclopenthiazide. |
| Metaraminol | Metaraminol may decrease the antihypertensive activities of Cyclopenthiazide. |
| Ergotamine | Ergotamine may decrease the antihypertensive activities of Cyclopenthiazide. |
| Nicergoline | Nicergoline may decrease the antihypertensive activities of Cyclopenthiazide. |
| Methoxamine | Methoxamine may decrease the antihypertensive activities of Cyclopenthiazide. |
| Trimipramine | Trimipramine may decrease the antihypertensive activities of Cyclopenthiazide. |
| Risperidone | Risperidone may decrease the antihypertensive activities of Cyclopenthiazide. |
| Phenmetrazine | Phenmetrazine may decrease the antihypertensive activities of Cyclopenthiazide. |
| Trifluoperazine | Trifluoperazine may decrease the antihypertensive activities of Cyclopenthiazide. |
| Pseudoephedrine | Pseudoephedrine may decrease the antihypertensive activities of Cyclopenthiazide. |
| Benzphetamine | Benzphetamine may decrease the antihypertensive activities of Cyclopenthiazide. |
| Diethylpropion | Diethylpropion may decrease the antihypertensive activities of Cyclopenthiazide. |
| Naratriptan | Naratriptan may decrease the antihypertensive activities of Cyclopenthiazide. |
| Frovatriptan | Frovatriptan may decrease the antihypertensive activities of Cyclopenthiazide. |
| Methoxyflurane | Methoxyflurane may decrease the antihypertensive activities of Cyclopenthiazide. |
| Ergoloid mesylate | Ergoloid mesylate may decrease the antihypertensive activities of Cyclopenthiazide. |
| Dutasteride | Dutasteride may decrease the antihypertensive activities of Cyclopenthiazide. |
| Propafenone | Propafenone may decrease the antihypertensive activities of Cyclopenthiazide. |
| Pergolide | Pergolide may decrease the antihypertensive activities of Cyclopenthiazide. |
| Finasteride | Finasteride may decrease the antihypertensive activities of Cyclopenthiazide. |
| Ergometrine | Ergometrine may decrease the antihypertensive activities of Cyclopenthiazide. |
| Lisdexamfetamine | Lisdexamfetamine may decrease the antihypertensive activities of Cyclopenthiazide. |
| Mephentermine | Mephentermine may decrease the antihypertensive activities of Cyclopenthiazide. |
| Yohimbine | Yohimbine may decrease the antihypertensive activities of Cyclopenthiazide. |
| MMDA | MMDA may decrease the antihypertensive activities of Cyclopenthiazide. |
| Midomafetamine | Midomafetamine may decrease the antihypertensive activities of Cyclopenthiazide. |
| 2,5-Dimethoxy-4-ethylamphetamine | 2,5-Dimethoxy-4-ethylamphetamine may decrease the antihypertensive activities of Cyclopenthiazide. |
| 4-Methoxyamphetamine | 4-Methoxyamphetamine may decrease the antihypertensive activities of Cyclopenthiazide. |
| 4-Bromo-2,5-dimethoxyamphetamine | 4-Bromo-2,5-dimethoxyamphetamine may decrease the antihypertensive activities of Cyclopenthiazide. |
| Tenamfetamine | Tenamfetamine may decrease the antihypertensive activities of Cyclopenthiazide. |
| Chlorphentermine | Chlorphentermine may decrease the antihypertensive activities of Cyclopenthiazide. |
| Dextroamphetamine | Dextroamphetamine may decrease the antihypertensive activities of Cyclopenthiazide. |
| Phendimetrazine | Phendimetrazine may decrease the antihypertensive activities of Cyclopenthiazide. |
| Periciazine | Periciazine may decrease the antihypertensive activities of Cyclopenthiazide. |
| Acepromazine | Acepromazine may decrease the antihypertensive activities of Cyclopenthiazide. |
| Thioproperazine | Thioproperazine may decrease the antihypertensive activities of Cyclopenthiazide. |
| Zuclopenthixol | Zuclopenthixol may decrease the antihypertensive activities of Cyclopenthiazide. |
| Epicaptopril | Epicaptopril may decrease the antihypertensive activities of Cyclopenthiazide. |
| 1-benzylimidazole | 1-benzylimidazole may decrease the antihypertensive activities of Cyclopenthiazide. |
| Lysergic acid diethylamide | Lysergic acid diethylamide may decrease the antihypertensive activities of Cyclopenthiazide. |
| Amineptine | Amineptine may decrease the antihypertensive activities of Cyclopenthiazide. |
| Dronedarone | Dronedarone may decrease the antihypertensive activities of Cyclopenthiazide. |
| Flibanserin | Flibanserin may decrease the antihypertensive activities of Cyclopenthiazide. |
| Iloperidone | Iloperidone may decrease the antihypertensive activities of Cyclopenthiazide. |
| Amibegron | Amibegron may decrease the antihypertensive activities of Cyclopenthiazide. |
| Naluzotan | Naluzotan may decrease the antihypertensive activities of Cyclopenthiazide. |
| Cariprazine | Cariprazine may decrease the antihypertensive activities of Cyclopenthiazide. |
| Mianserin | Mianserin may decrease the antihypertensive activities of Cyclopenthiazide. |
| Nylidrin | Nylidrin may decrease the antihypertensive activities of Cyclopenthiazide. |
| Solabegron | Solabegron may decrease the antihypertensive activities of Cyclopenthiazide. |
| Asenapine | Asenapine may decrease the antihypertensive activities of Cyclopenthiazide. |
| Esmirtazapine | Esmirtazapine may decrease the antihypertensive activities of Cyclopenthiazide. |
| Vilazodone | Vilazodone may decrease the antihypertensive activities of Cyclopenthiazide. |
| Nitrous oxide | Nitrous oxide may decrease the antihypertensive activities of Cyclopenthiazide. |
| Xylometazoline | Xylometazoline may decrease the antihypertensive activities of Cyclopenthiazide. |
| Isometheptene | Isometheptene may decrease the antihypertensive activities of Cyclopenthiazide. |
| Naphazoline | Naphazoline may decrease the antihypertensive activities of Cyclopenthiazide. |
| Tetryzoline | Tetryzoline may decrease the antihypertensive activities of Cyclopenthiazide. |
| Cinitapride | Cinitapride may decrease the antihypertensive activities of Cyclopenthiazide. |
| Lurasidone | Lurasidone may decrease the antihypertensive activities of Cyclopenthiazide. |
| Tyramine | Tyramine may decrease the antihypertensive activities of Cyclopenthiazide. |
| Adrafinil | Adrafinil may decrease the antihypertensive activities of Cyclopenthiazide. |
| Ifenprodil | Ifenprodil may decrease the antihypertensive activities of Cyclopenthiazide. |
| Etilefrine | Etilefrine may decrease the antihypertensive activities of Cyclopenthiazide. |
| Butriptyline | Butriptyline may decrease the antihypertensive activities of Cyclopenthiazide. |
| Cannabidiol | Cannabidiol may decrease the antihypertensive activities of Cyclopenthiazide. |
| Brexpiprazole | Brexpiprazole may decrease the antihypertensive activities of Cyclopenthiazide. |
| Cirazoline | Cirazoline may decrease the antihypertensive activities of Cyclopenthiazide. |
| Synephrine | Synephrine may decrease the antihypertensive activities of Cyclopenthiazide. |
| Tianeptine | Tianeptine may decrease the antihypertensive activities of Cyclopenthiazide. |
| Oxaprotiline | Oxaprotiline may decrease the antihypertensive activities of Cyclopenthiazide. |
| Iofetamine I-123 | Iofetamine I-123 may decrease the antihypertensive activities of Cyclopenthiazide. |
| Dihydroergocornine | Dihydroergocornine may decrease the antihypertensive activities of Cyclopenthiazide. |
| Amitraz | Amitraz may decrease the antihypertensive activities of Cyclopenthiazide. |
| Medetomidine | Medetomidine may decrease the antihypertensive activities of Cyclopenthiazide. |