Simfibrate

DB13433

small molecule experimental

Deskripsi

Struktur Molekul 2D

Berat 469.36
Wujud -

Peta Jejaring Molekuler
Legenda: ObatTargetGenEnzim(Panah → menunjukkan arah efek / relasi)TransporterCarrier

Profil Farmakokinetik

Waktu Paruh (Half-Life) -
Volume Distribusi -
Klirens (Clearance) -

Absorpsi

Data absorpsi tidak tersedia.

Metabolisme

Data metabolisme tidak tersedia.

Rute Eliminasi

Data eliminasi belum tersedia.

Interaksi Obat

157 Data
Clofibrate The risk or severity of adverse effects can be increased when Clofibrate is combined with Simfibrate.
Fenofibrate The risk or severity of adverse effects can be increased when Fenofibrate is combined with Simfibrate.
Gemfibrozil The risk or severity of adverse effects can be increased when Gemfibrozil is combined with Simfibrate.
Bezafibrate The risk or severity of adverse effects can be increased when Bezafibrate is combined with Simfibrate.
Etofibrate The risk or severity of adverse effects can be increased when Etofibrate is combined with Simfibrate.
Ciprofibrate The risk or severity of adverse effects can be increased when Ciprofibrate is combined with Simfibrate.
Ronifibrate The risk or severity of adverse effects can be increased when Simfibrate is combined with Ronifibrate.
Aluminium clofibrate The risk or severity of adverse effects can be increased when Simfibrate is combined with Aluminium clofibrate.
Clofibride The risk or severity of adverse effects can be increased when Simfibrate is combined with Clofibride.
Fenofibric acid The risk or severity of adverse effects can be increased when Simfibrate is combined with Fenofibric acid.
Ezetimibe The serum concentration of Ezetimibe can be increased when it is combined with Simfibrate.
Glycochenodeoxycholic Acid The therapeutic efficacy of Glycochenodeoxycholic Acid can be decreased when used in combination with Simfibrate.
Cholic Acid The therapeutic efficacy of Cholic Acid can be decreased when used in combination with Simfibrate.
Glycocholic acid The therapeutic efficacy of Glycocholic acid can be decreased when used in combination with Simfibrate.
Deoxycholic acid The therapeutic efficacy of Deoxycholic acid can be decreased when used in combination with Simfibrate.
Taurocholic acid The therapeutic efficacy of Taurocholic acid can be decreased when used in combination with Simfibrate.
Obeticholic acid The therapeutic efficacy of Obeticholic acid can be decreased when used in combination with Simfibrate.
Chenodeoxycholic acid The therapeutic efficacy of Chenodeoxycholic acid can be decreased when used in combination with Simfibrate.
Taurochenodeoxycholic acid The therapeutic efficacy of Taurochenodeoxycholic acid can be decreased when used in combination with Simfibrate.
Tauroursodeoxycholic acid The therapeutic efficacy of Tauroursodeoxycholic acid can be decreased when used in combination with Simfibrate.
Bamet-UD2 The therapeutic efficacy of Bamet-UD2 can be decreased when used in combination with Simfibrate.
Dehydrocholic acid The therapeutic efficacy of Dehydrocholic acid can be decreased when used in combination with Simfibrate.
Hyodeoxycholic Acid The therapeutic efficacy of Hyodeoxycholic Acid can be decreased when used in combination with Simfibrate.
Ursodeoxycholic acid The therapeutic efficacy of Ursodeoxycholic acid can be decreased when used in combination with Simfibrate.
Cyclosporine The risk or severity of renal failure can be increased when Cyclosporine is combined with Simfibrate.
Glimepiride The risk or severity of hypoglycemia can be increased when Simfibrate is combined with Glimepiride.
Acetohexamide The risk or severity of hypoglycemia can be increased when Simfibrate is combined with Acetohexamide.
Chlorpropamide The risk or severity of hypoglycemia can be increased when Simfibrate is combined with Chlorpropamide.
Tolazamide The risk or severity of hypoglycemia can be increased when Simfibrate is combined with Tolazamide.
Glyburide The risk or severity of hypoglycemia can be increased when Simfibrate is combined with Glyburide.
Glipizide The risk or severity of hypoglycemia can be increased when Simfibrate is combined with Glipizide.
Gliclazide The risk or severity of hypoglycemia can be increased when Simfibrate is combined with Gliclazide.
Tolbutamide The risk or severity of hypoglycemia can be increased when Simfibrate is combined with Tolbutamide.
Gliquidone The risk or severity of hypoglycemia can be increased when Simfibrate is combined with Gliquidone.
Glisoxepide The risk or severity of hypoglycemia can be increased when Simfibrate is combined with Glisoxepide.
Glibornuride The risk or severity of hypoglycemia can be increased when Simfibrate is combined with Glibornuride.
Carbutamide The risk or severity of hypoglycemia can be increased when Simfibrate is combined with Carbutamide.
Metahexamide The risk or severity of hypoglycemia can be increased when Simfibrate is combined with Metahexamide.
Colestipol Colestipol can cause a decrease in the absorption of Simfibrate resulting in a reduced serum concentration and potentially a decrease in efficacy.
Sevelamer Sevelamer can cause a decrease in the absorption of Simfibrate resulting in a reduced serum concentration and potentially a decrease in efficacy.
Colesevelam Colesevelam can cause a decrease in the absorption of Simfibrate resulting in a reduced serum concentration and potentially a decrease in efficacy.
Cholestyramine Cholestyramine can cause a decrease in the absorption of Simfibrate resulting in a reduced serum concentration and potentially a decrease in efficacy.
Dicoumarol The risk or severity of bleeding can be increased when Simfibrate is combined with Dicoumarol.
Phenindione The risk or severity of bleeding can be increased when Simfibrate is combined with Phenindione.
Warfarin The risk or severity of bleeding can be increased when Simfibrate is combined with Warfarin.
Phenprocoumon The risk or severity of bleeding can be increased when Simfibrate is combined with Phenprocoumon.
Acenocoumarol The risk or severity of bleeding can be increased when Simfibrate is combined with Acenocoumarol.
4-hydroxycoumarin The risk or severity of bleeding can be increased when Simfibrate is combined with 4-hydroxycoumarin.
Coumarin The risk or severity of bleeding can be increased when Simfibrate is combined with Coumarin.
(R)-warfarin The risk or severity of bleeding can be increased when Simfibrate is combined with (R)-warfarin.
Ethyl biscoumacetate The risk or severity of bleeding can be increased when Simfibrate is combined with Ethyl biscoumacetate.
Fluindione The risk or severity of bleeding can be increased when Simfibrate is combined with Fluindione.
Clorindione The risk or severity of bleeding can be increased when Simfibrate is combined with Clorindione.
Diphenadione The risk or severity of bleeding can be increased when Simfibrate is combined with Diphenadione.
Tioclomarol The risk or severity of bleeding can be increased when Simfibrate is combined with Tioclomarol.
(S)-Warfarin The risk or severity of bleeding can be increased when Simfibrate is combined with (S)-Warfarin.
Tacrolimus Tacrolimus may increase the nephrotoxic activities of Simfibrate.
Pravastatin The risk or severity of myopathy and rhabdomyolysis can be increased when Simfibrate is combined with Pravastatin.
Lovastatin The risk or severity of myopathy and rhabdomyolysis can be increased when Simfibrate is combined with Lovastatin.
Cerivastatin The risk or severity of myopathy and rhabdomyolysis can be increased when Simfibrate is combined with Cerivastatin.
Simvastatin The risk or severity of myopathy and rhabdomyolysis can be increased when Simfibrate is combined with Simvastatin.
Atorvastatin The risk or severity of myopathy and rhabdomyolysis can be increased when Simfibrate is combined with Atorvastatin.
Fluvastatin The risk or severity of myopathy and rhabdomyolysis can be increased when Simfibrate is combined with Fluvastatin.
Rosuvastatin The risk or severity of myopathy and rhabdomyolysis can be increased when Simfibrate is combined with Rosuvastatin.
Mevastatin The risk or severity of myopathy and rhabdomyolysis can be increased when Simfibrate is combined with Mevastatin.
Pitavastatin The risk or severity of myopathy and rhabdomyolysis can be increased when Simfibrate is combined with Pitavastatin.
Leuprolide The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Leuprolide is combined with Simfibrate.
Somatotropin The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Somatotropin is combined with Simfibrate.
Infliximab The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Infliximab is combined with Simfibrate.
Daptomycin The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Daptomycin is combined with Simfibrate.
Baclofen The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Baclofen is combined with Simfibrate.
Sildenafil The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Sildenafil is combined with Simfibrate.
Indinavir The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Indinavir is combined with Simfibrate.
Cladribine The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Cladribine is combined with Simfibrate.
Phenytoin The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Phenytoin is combined with Simfibrate.
Pamidronic acid The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Pamidronic acid is combined with Simfibrate.
Mefloquine The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Mefloquine is combined with Simfibrate.
Tacrine The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Tacrine is combined with Simfibrate.
Carbimazole The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Carbimazole is combined with Simfibrate.
Trimethoprim The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Trimethoprim is combined with Simfibrate.
Betamethasone The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Betamethasone is combined with Simfibrate.
Montelukast The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Montelukast is combined with Simfibrate.
Zidovudine The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Zidovudine is combined with Simfibrate.
Cimetidine The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Cimetidine is combined with Simfibrate.
Ritonavir The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Ritonavir is combined with Simfibrate.
Lercanidipine The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Lercanidipine is combined with Simfibrate.
Ciprofloxacin The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Ciprofloxacin is combined with Simfibrate.
Vincristine The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Vincristine is combined with Simfibrate.
Propylthiouracil The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Propylthiouracil is combined with Simfibrate.
Methotrexate The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Methotrexate is combined with Simfibrate.
Enalapril The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Enalapril is combined with Simfibrate.
Nizatidine The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Nizatidine is combined with Simfibrate.
Ivermectin The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Ivermectin is combined with Simfibrate.
Chloroquine The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Chloroquine is combined with Simfibrate.
Triamcinolone The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Triamcinolone is combined with Simfibrate.
Niacin The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Niacin is combined with Simfibrate.
Alendronic acid The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Alendronic acid is combined with Simfibrate.
Stavudine The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Stavudine is combined with Simfibrate.
Nafarelin The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Nafarelin is combined with Simfibrate.
Amphotericin B The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Amphotericin B is combined with Simfibrate.

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