Clorindione

DB13275

small molecule experimental

Deskripsi

Clorindione is a vitamin K antagonist, which may be useful to decrease prothrombin levels in humans.

Struktur Molekul 2D

Berat 256.69
Wujud -

Peta Jejaring Molekuler
Legenda: ObatTargetGenEnzim(Panah → menunjukkan arah efek / relasi)TransporterCarrier

Profil Farmakokinetik

Waktu Paruh (Half-Life) -
Volume Distribusi -
Klirens (Clearance) -

Absorpsi

Data absorpsi tidak tersedia.

Metabolisme

Data metabolisme tidak tersedia.

Rute Eliminasi

Data eliminasi belum tersedia.

Interaksi Makanan

1 Data
  • 1. Avoid herbs and supplements with anticoagulant/antiplatelet activity. These may increase anticoagulant/antiplatelet activity of clorindione. Examples include garlic, ginger, bilberry, danshen, piracetam, and ginkgo biloba.

Interaksi Obat

1293 Data
Apixaban Apixaban may increase the anticoagulant activities of Clorindione.
Dabigatran etexilate Dabigatran etexilate may increase the anticoagulant activities of Clorindione.
Dasatinib The risk or severity of bleeding and hemorrhage can be increased when Dasatinib is combined with Clorindione.
Deferasirox The risk or severity of gastrointestinal bleeding can be increased when Clorindione is combined with Deferasirox.
Ursodeoxycholic acid The risk or severity of bleeding and bruising can be increased when Clorindione is combined with Ursodeoxycholic acid.
Glycochenodeoxycholic Acid The risk or severity of bleeding and bruising can be increased when Clorindione is combined with Glycochenodeoxycholic Acid.
Cholic Acid The risk or severity of bleeding and bruising can be increased when Clorindione is combined with Cholic Acid.
Glycocholic acid The risk or severity of bleeding and bruising can be increased when Clorindione is combined with Glycocholic acid.
Deoxycholic acid The risk or severity of bleeding and bruising can be increased when Clorindione is combined with Deoxycholic acid.
Taurocholic acid The risk or severity of bleeding and bruising can be increased when Clorindione is combined with Taurocholic acid.
Obeticholic acid The risk or severity of bleeding and bruising can be increased when Clorindione is combined with Obeticholic acid.
Chenodeoxycholic acid The risk or severity of bleeding and bruising can be increased when Clorindione is combined with Chenodeoxycholic acid.
Taurochenodeoxycholic acid The risk or severity of bleeding and bruising can be increased when Clorindione is combined with Taurochenodeoxycholic acid.
Tauroursodeoxycholic acid The risk or severity of bleeding and bruising can be increased when Clorindione is combined with Tauroursodeoxycholic acid.
Bamet-UD2 The risk or severity of bleeding and bruising can be increased when Clorindione is combined with Bamet-UD2.
Dehydrocholic acid The risk or severity of bleeding and bruising can be increased when Clorindione is combined with Dehydrocholic acid.
Hyodeoxycholic Acid The risk or severity of bleeding and bruising can be increased when Clorindione is combined with Hyodeoxycholic Acid.
Edoxaban The risk or severity of bleeding can be increased when Edoxaban is combined with Clorindione.
Ibrutinib The risk or severity of bleeding and hemorrhage can be increased when Ibrutinib is combined with Clorindione.
Obinutuzumab The risk or severity of bleeding and hemorrhage can be increased when Clorindione is combined with Obinutuzumab.
Rivaroxaban Clorindione may increase the anticoagulant activities of Rivaroxaban.
Sugammadex The risk or severity of bleeding and hemorrhage can be increased when Clorindione is combined with Sugammadex.
Tibolone Tibolone may increase the anticoagulant activities of Clorindione.
Tipranavir The risk or severity of bleeding and hemorrhage can be increased when Tipranavir is combined with Clorindione.
Urokinase Urokinase may increase the anticoagulant activities of Clorindione.
Vitamin E Vitamin E may increase the anticoagulant activities of Clorindione.
Vorapaxar The risk or severity of bleeding and hemorrhage can be increased when Vorapaxar is combined with Clorindione.
Gemcitabine The therapeutic efficacy of Clorindione can be increased when used in combination with Gemcitabine.
Flunisolide Flunisolide may increase the anticoagulant activities of Clorindione.
Beclomethasone dipropionate Beclomethasone dipropionate may increase the anticoagulant activities of Clorindione.
Betamethasone Betamethasone may increase the anticoagulant activities of Clorindione.
Fluticasone propionate Fluticasone propionate may increase the anticoagulant activities of Clorindione.
Fluocinolone acetonide Fluocinolone acetonide may increase the anticoagulant activities of Clorindione.
Prednisone Prednisone may increase the anticoagulant activities of Clorindione.
Fludrocortisone Fludrocortisone may increase the anticoagulant activities of Clorindione.
Hydrocortisone Hydrocortisone may increase the anticoagulant activities of Clorindione.
Prednisolone Prednisolone may increase the anticoagulant activities of Clorindione.
Methylprednisolone Methylprednisolone may increase the anticoagulant activities of Clorindione.
Trilostane Trilostane may increase the anticoagulant activities of Clorindione.
Budesonide Budesonide may increase the anticoagulant activities of Clorindione.
Dexamethasone Dexamethasone may increase the anticoagulant activities of Clorindione.
Corticotropin Corticotropin may increase the anticoagulant activities of Clorindione.
Cortisone acetate Cortisone acetate may increase the anticoagulant activities of Clorindione.
Paramethasone Paramethasone may increase the anticoagulant activities of Clorindione.
Ciclesonide Ciclesonide may increase the anticoagulant activities of Clorindione.
Aldosterone Aldosterone may increase the anticoagulant activities of Clorindione.
Fluticasone furoate Fluticasone furoate may increase the anticoagulant activities of Clorindione.
Fluprednidene Fluprednidene may increase the anticoagulant activities of Clorindione.
Tixocortol Tixocortol may increase the anticoagulant activities of Clorindione.
Fluprednisolone Fluprednisolone may increase the anticoagulant activities of Clorindione.
Meprednisone Meprednisone may increase the anticoagulant activities of Clorindione.
Dexamethasone isonicotinate Dexamethasone isonicotinate may increase the anticoagulant activities of Clorindione.
Melengestrol Melengestrol may increase the anticoagulant activities of Clorindione.
Deflazacort Deflazacort may increase the anticoagulant activities of Clorindione.
Cortivazol Cortivazol may increase the anticoagulant activities of Clorindione.
Prednylidene Prednylidene may increase the anticoagulant activities of Clorindione.
Fluocortin Fluocortin may increase the anticoagulant activities of Clorindione.
Fluperolone Fluperolone may increase the anticoagulant activities of Clorindione.
Cloprednol Cloprednol may increase the anticoagulant activities of Clorindione.
Fluclorolone Fluclorolone may increase the anticoagulant activities of Clorindione.
Fluticasone Fluticasone may increase the anticoagulant activities of Clorindione.
Mometasone furoate Mometasone furoate may increase the anticoagulant activities of Clorindione.
Hydrocortisone acetate Hydrocortisone acetate may increase the anticoagulant activities of Clorindione.
Hydrocortisone cypionate Hydrocortisone cypionate may increase the anticoagulant activities of Clorindione.
Hydrocortisone succinate Hydrocortisone succinate may increase the anticoagulant activities of Clorindione.
Prednisolone phosphate Prednisolone phosphate may increase the anticoagulant activities of Clorindione.
Prednisolone hemisuccinate Prednisolone hemisuccinate may increase the anticoagulant activities of Clorindione.
Methylprednisolone hemisuccinate Methylprednisolone hemisuccinate may increase the anticoagulant activities of Clorindione.
Prednisone acetate Prednisone acetate may increase the anticoagulant activities of Clorindione.
Clocortolone acetate Clocortolone acetate may increase the anticoagulant activities of Clorindione.
Melengestrol acetate Melengestrol acetate may increase the anticoagulant activities of Clorindione.
Betamethasone phosphate Betamethasone phosphate may increase the anticoagulant activities of Clorindione.
Cortisone Cortisone may increase the anticoagulant activities of Clorindione.
Clobetasol propionate Clobetasol propionate may increase the anticoagulant activities of Clorindione.
Fluocinonide Fluocinonide may increase the anticoagulant activities of Clorindione.
Hydrocortisone butyrate Hydrocortisone butyrate may increase the anticoagulant activities of Clorindione.
Desoximetasone Desoximetasone may increase the anticoagulant activities of Clorindione.
Mometasone Mometasone may increase the anticoagulant activities of Clorindione.
Fluocortolone Fluocortolone may increase the anticoagulant activities of Clorindione.
Prednisolone acetate Prednisolone acetate may increase the anticoagulant activities of Clorindione.
Fluorometholone Fluorometholone may increase the anticoagulant activities of Clorindione.
Difluocortolone Difluocortolone may increase the anticoagulant activities of Clorindione.
Flumethasone Flumethasone may increase the anticoagulant activities of Clorindione.
Methylprednisolone aceponate Methylprednisolone aceponate may increase the anticoagulant activities of Clorindione.
Erlotinib The serum concentration of Clorindione can be increased when it is combined with Erlotinib.
Acetaminophen Acetaminophen may increase the anticoagulant activities of Clorindione.
Allopurinol The risk or severity of bleeding can be increased when Allopurinol is combined with Clorindione.
Azathioprine The therapeutic efficacy of Clorindione can be decreased when used in combination with Azathioprine.
Chloral hydrate The protein binding of Clorindione can be decreased when combined with Chloral hydrate.
Methylphenidate The metabolism of Clorindione can be decreased when combined with Methylphenidate.
Dexmethylphenidate The metabolism of Clorindione can be decreased when combined with Dexmethylphenidate.
Disulfiram Disulfiram may increase the anticoagulant activities of Clorindione.
Etacrynic acid The protein binding of Clorindione can be decreased when combined with Etacrynic acid.
Ethotoin The therapeutic efficacy of Clorindione can be increased when used in combination with Ethotoin.
Etoposide The therapeutic efficacy of Clorindione can be increased when used in combination with Etoposide.
Exenatide Exenatide can cause an increase in the absorption of Clorindione resulting in an increased serum concentration and potentially a worsening of adverse effects.
Gefitinib Gefitinib may increase the anticoagulant activities of Clorindione.
Ginkgo biloba Ginkgo biloba may increase the anticoagulant activities of Clorindione.
Glutethimide The therapeutic efficacy of Clorindione can be decreased when used in combination with Glutethimide.
Ifosfamide The risk or severity of bleeding can be increased when Ifosfamide is combined with Clorindione.

Referensi & Sumber

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Sekuens Gen/Protein (FASTA)

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