Clothiapine

DB13256

small molecule approved

Deskripsi

Clothiapine has been approved in European countries and is an atypical antipsychotic, shown to be useful in some treatment-resistant patients.

Struktur Molekul 2D

Berat 343.87
Wujud -

Peta Jejaring Molekuler
Legenda: ObatTargetGenEnzim(Panah → menunjukkan arah efek / relasi)TransporterCarrier

Profil Farmakokinetik

Waktu Paruh (Half-Life) -
Volume Distribusi -
Klirens (Clearance) -

Absorpsi

Data absorpsi tidak tersedia.

Metabolisme

Data metabolisme tidak tersedia.

Rute Eliminasi

Data eliminasi belum tersedia.

Interaksi Obat

714 Data
Buprenorphine Clothiapine may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Doxylamine Doxylamine may increase the central nervous system depressant (CNS depressant) activities of Clothiapine.
Dronabinol Dronabinol may increase the central nervous system depressant (CNS depressant) activities of Clothiapine.
Droperidol Droperidol may increase the central nervous system depressant (CNS depressant) activities of Clothiapine.
Hydrocodone Clothiapine may increase the central nervous system depressant (CNS depressant) activities of Hydrocodone.
Hydroxyzine Hydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Clothiapine.
Magnesium sulfate The therapeutic efficacy of Clothiapine can be increased when used in combination with Magnesium sulfate.
Methotrimeprazine Clothiapine may increase the central nervous system depressant (CNS depressant) activities of Methotrimeprazine.
Metyrosine Clothiapine may increase the sedative activities of Metyrosine.
Minocycline Minocycline may increase the central nervous system depressant (CNS depressant) activities of Clothiapine.
Mirtazapine Clothiapine may increase the central nervous system depressant (CNS depressant) activities of Mirtazapine.
Nabilone Nabilone may increase the central nervous system depressant (CNS depressant) activities of Clothiapine.
Orphenadrine Clothiapine may increase the central nervous system depressant (CNS depressant) activities of Orphenadrine.
Paraldehyde Clothiapine may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
Perampanel Perampanel may increase the central nervous system depressant (CNS depressant) activities of Clothiapine.
Pramipexole Clothiapine may increase the sedative activities of Pramipexole.
Ropinirole Clothiapine may increase the sedative activities of Ropinirole.
Rotigotine Clothiapine may increase the sedative activities of Rotigotine.
Rufinamide The risk or severity of adverse effects can be increased when Rufinamide is combined with Clothiapine.
Sodium oxybate Clothiapine may increase the central nervous system depressant (CNS depressant) activities of Sodium oxybate.
Suvorexant Clothiapine may increase the central nervous system depressant (CNS depressant) activities of Suvorexant.
Tapentadol Tapentadol may increase the central nervous system depressant (CNS depressant) activities of Clothiapine.
Thalidomide Clothiapine may increase the central nervous system depressant (CNS depressant) activities of Thalidomide.
Zolpidem Clothiapine may increase the central nervous system depressant (CNS depressant) activities of Zolpidem.
Amisulpride Clothiapine may increase the antipsychotic activities of Amisulpride.
Methylphenidate The risk or severity of adverse effects can be increased when Clothiapine is combined with Methylphenidate.
Dexmethylphenidate The risk or severity of adverse effects can be increased when Clothiapine is combined with Dexmethylphenidate.
Metoclopramide The risk or severity of adverse effects can be increased when Metoclopramide is combined with Clothiapine.
Quinagolide The therapeutic efficacy of Quinagolide can be decreased when used in combination with Clothiapine.
Sulpiride Clothiapine may increase the antipsychotic activities of Sulpiride.
Methadone The risk or severity of adverse effects can be increased when Methadone is combined with Clothiapine.
Lithium citrate Lithium citrate may increase the neurotoxic activities of Clothiapine.
Lithium hydroxide Lithium hydroxide may increase the neurotoxic activities of Clothiapine.
Mequitazine Clothiapine may increase the arrhythmogenic activities of Mequitazine.
Tetrabenazine The risk or severity of adverse effects can be increased when Clothiapine is combined with Tetrabenazine.
Deutetrabenazine The risk or severity of adverse effects can be increased when Clothiapine is combined with Deutetrabenazine.
Ethanol Clothiapine may increase the central nervous system depressant (CNS depressant) activities of Ethanol.
Azelastine Clothiapine may increase the central nervous system depressant (CNS depressant) activities of Azelastine.
Brimonidine Brimonidine may increase the central nervous system depressant (CNS depressant) activities of Clothiapine.
Zimelidine The risk or severity of adverse effects can be increased when Clothiapine is combined with Zimelidine.
Dapoxetine The risk or severity of adverse effects can be increased when Clothiapine is combined with Dapoxetine.
Seproxetine The risk or severity of adverse effects can be increased when Clothiapine is combined with Seproxetine.
Fluvoxamine The risk or severity of adverse effects can be increased when Clothiapine is combined with Fluvoxamine.
Citalopram The risk or severity of adverse effects can be increased when Clothiapine is combined with Citalopram.
Duloxetine The risk or severity of adverse effects can be increased when Clothiapine is combined with Duloxetine.
Trazodone The risk or severity of adverse effects can be increased when Clothiapine is combined with Trazodone.
Paroxetine The risk or severity of adverse effects can be increased when Clothiapine is combined with Paroxetine.
Sertraline The risk or severity of adverse effects can be increased when Clothiapine is combined with Sertraline.
Sibutramine The risk or severity of adverse effects can be increased when Clothiapine is combined with Sibutramine.
Nefazodone The risk or severity of adverse effects can be increased when Clothiapine is combined with Nefazodone.
Escitalopram The risk or severity of adverse effects can be increased when Clothiapine is combined with Escitalopram.
Milnacipran The risk or severity of adverse effects can be increased when Clothiapine is combined with Milnacipran.
Desvenlafaxine The risk or severity of adverse effects can be increased when Clothiapine is combined with Desvenlafaxine.
Levomilnacipran The risk or severity of adverse effects can be increased when Levomilnacipran is combined with Clothiapine.
Indalpine The risk or severity of adverse effects can be increased when Clothiapine is combined with Indalpine.
Ritanserin The risk or severity of adverse effects can be increased when Clothiapine is combined with Ritanserin.
Alaproclate The risk or severity of adverse effects can be increased when Clothiapine is combined with Alaproclate.
Cyproheptadine The risk or severity of CNS depression can be increased when Cyproheptadine is combined with Clothiapine.
Propiomazine The risk or severity of CNS depression can be increased when Propiomazine is combined with Clothiapine.
Zopiclone The risk or severity of adverse effects can be increased when Clothiapine is combined with Zopiclone.
Eletriptan The risk or severity of adverse effects can be increased when Eletriptan is combined with Clothiapine.
Cabergoline The risk or severity of adverse effects can be increased when Cabergoline is combined with Clothiapine.
Zolmitriptan The risk or severity of adverse effects can be increased when Zolmitriptan is combined with Clothiapine.
Dihydroergotamine The risk or severity of adverse effects can be increased when Dihydroergotamine is combined with Clothiapine.
Meperidine The risk or severity of adverse effects can be increased when Meperidine is combined with Clothiapine.
Dextromethorphan The risk or severity of adverse effects can be increased when Dextromethorphan is combined with Clothiapine.
Mazindol The risk or severity of adverse effects can be increased when Mazindol is combined with Clothiapine.
Linezolid The risk or severity of adverse effects can be increased when Linezolid is combined with Clothiapine.
Sumatriptan The risk or severity of adverse effects can be increased when Sumatriptan is combined with Clothiapine.
Ergotamine The risk or severity of adverse effects can be increased when Ergotamine is combined with Clothiapine.
Fentanyl The risk or severity of adverse effects can be increased when Fentanyl is combined with Clothiapine.
Almotriptan The risk or severity of adverse effects can be increased when Almotriptan is combined with Clothiapine.
Naratriptan The risk or severity of adverse effects can be increased when Naratriptan is combined with Clothiapine.
Rizatriptan The risk or severity of adverse effects can be increased when Rizatriptan is combined with Clothiapine.
Frovatriptan The risk or severity of adverse effects can be increased when Frovatriptan is combined with Clothiapine.
Ergoloid mesylate The risk or severity of adverse effects can be increased when Ergoloid mesylate is combined with Clothiapine.
Chlorpheniramine The risk or severity of adverse effects can be increased when Chlorpheniramine is combined with Clothiapine.
Procarbazine The risk or severity of adverse effects can be increased when Procarbazine is combined with Clothiapine.
Bromocriptine The risk or severity of adverse effects can be increased when Bromocriptine is combined with Clothiapine.
Ergometrine The risk or severity of adverse effects can be increased when Ergometrine is combined with Clothiapine.
Rasagiline The risk or severity of adverse effects can be increased when Rasagiline is combined with Clothiapine.
Lorcaserin The risk or severity of adverse effects can be increased when Lorcaserin is combined with Clothiapine.
Etoperidone The risk or severity of adverse effects can be increased when Etoperidone is combined with Clothiapine.
Lorpiprazole The risk or severity of adverse effects can be increased when Lorpiprazole is combined with Clothiapine.
Amphetamine Clothiapine may decrease the stimulatory activities of Amphetamine.
Phentermine Clothiapine may decrease the stimulatory activities of Phentermine.
Pseudoephedrine Clothiapine may decrease the stimulatory activities of Pseudoephedrine.
Benzphetamine Clothiapine may decrease the stimulatory activities of Benzphetamine.
Diethylpropion Clothiapine may decrease the stimulatory activities of Diethylpropion.
Lisdexamfetamine Clothiapine may decrease the stimulatory activities of Lisdexamfetamine.
Mephentermine Clothiapine may decrease the stimulatory activities of Mephentermine.
MMDA Clothiapine may decrease the stimulatory activities of MMDA.
2,5-Dimethoxy-4-ethylamphetamine Clothiapine may decrease the stimulatory activities of 2,5-Dimethoxy-4-ethylamphetamine.
Chlorphentermine Clothiapine may decrease the stimulatory activities of Chlorphentermine.
Methylenedioxyethamphetamine Clothiapine may decrease the stimulatory activities of Methylenedioxyethamphetamine.
Dextroamphetamine Clothiapine may decrease the stimulatory activities of Dextroamphetamine.
Metamfetamine Clothiapine may decrease the stimulatory activities of Metamfetamine.
Iofetamine I-123 Clothiapine may decrease the stimulatory activities of Iofetamine I-123.
Ritobegron Clothiapine may decrease the stimulatory activities of Ritobegron.
Mephedrone Clothiapine may decrease the stimulatory activities of Mephedrone.

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