Prifinium

DB13254

small molecule experimental

Deskripsi

Prifinium is an antimuscarinic agent with antispasmodic and antiemetic properties. It may be useful for the treatment of irritable bowel syndrome A175027.

Struktur Molekul 2D

Berat 306.472
Wujud -

Peta Jejaring Molekuler
Legenda: ObatTargetGenEnzim(Panah → menunjukkan arah efek / relasi)TransporterCarrier

Profil Farmakokinetik

Waktu Paruh (Half-Life) -
Volume Distribusi -
Klirens (Clearance) -

Absorpsi

Data absorpsi tidak tersedia.

Metabolisme

Data metabolisme tidak tersedia.

Rute Eliminasi

Data eliminasi belum tersedia.

Interaksi Obat

516 Data
Aclidinium The risk or severity of adverse effects can be increased when Prifinium is combined with Aclidinium.
Mianserin Mianserin may increase the anticholinergic activities of Prifinium.
Mirabegron The risk or severity of urinary retention can be increased when Prifinium is combined with Mirabegron.
Pramlintide The risk or severity of reduced gastrointestinal motility can be increased when Pramlintide is combined with Prifinium.
Secretin porcine The therapeutic efficacy of Secretin porcine can be decreased when used in combination with Prifinium.
Tiotropium The risk or severity of adverse effects can be increased when Prifinium is combined with Tiotropium.
Topiramate The risk or severity of hyperthermia and oligohydrosis can be increased when Prifinium is combined with Topiramate.
Umeclidinium The risk or severity of adverse effects can be increased when Prifinium is combined with Umeclidinium.
Glycopyrronium The risk or severity of adverse effects can be increased when Prifinium is combined with Glycopyrronium.
Botulinum toxin type A The risk or severity of adverse effects can be increased when Prifinium is combined with Botulinum toxin type A.
Glucagon Prifinium may increase the gastrointestinal motility reducing activities of Glucagon.
Sulpiride Prifinium may increase the anticholinergic activities of Sulpiride.
Botulinum toxin type B The risk or severity of adverse effects can be increased when Prifinium is combined with Botulinum toxin type B.
Eluxadoline The risk or severity of constipation can be increased when Prifinium is combined with Eluxadoline.
Ramosetron The risk or severity of constipation can be increased when Prifinium is combined with Ramosetron.
Naltrexone The risk or severity of adverse effects can be increased when Prifinium is combined with Naltrexone.
Bezitramide The risk or severity of adverse effects can be increased when Prifinium is combined with Bezitramide.
Tramadol The risk or severity of adverse effects can be increased when Prifinium is combined with Tramadol.
Morphine The risk or severity of adverse effects can be increased when Prifinium is combined with Morphine.
Codeine The risk or severity of adverse effects can be increased when Prifinium is combined with Codeine.
Hydromorphone The risk or severity of adverse effects can be increased when Prifinium is combined with Hydromorphone.
Methadone The risk or severity of adverse effects can be increased when Prifinium is combined with Methadone.
Meperidine The risk or severity of adverse effects can be increased when Prifinium is combined with Meperidine.
Oxycodone The risk or severity of adverse effects can be increased when Prifinium is combined with Oxycodone.
Butorphanol The risk or severity of adverse effects can be increased when Prifinium is combined with Butorphanol.
Dextropropoxyphene The risk or severity of adverse effects can be increased when Prifinium is combined with Dextropropoxyphene.
Pentazocine The risk or severity of adverse effects can be increased when Prifinium is combined with Pentazocine.
Sufentanil The risk or severity of adverse effects can be increased when Prifinium is combined with Sufentanil.
Alfentanil The risk or severity of adverse effects can be increased when Prifinium is combined with Alfentanil.
Fentanyl The risk or severity of adverse effects can be increased when Prifinium is combined with Fentanyl.
Nalbuphine The risk or severity of adverse effects can be increased when Prifinium is combined with Nalbuphine.
Levorphanol The risk or severity of adverse effects can be increased when Prifinium is combined with Levorphanol.
Remifentanil The risk or severity of adverse effects can be increased when Prifinium is combined with Remifentanil.
Buprenorphine The risk or severity of adverse effects can be increased when Prifinium is combined with Buprenorphine.
Hydrocodone The risk or severity of adverse effects can be increased when Prifinium is combined with Hydrocodone.
Diphenoxylate The risk or severity of adverse effects can be increased when Prifinium is combined with Diphenoxylate.
Oxymorphone The risk or severity of adverse effects can be increased when Prifinium is combined with Oxymorphone.
Dezocine The risk or severity of adverse effects can be increased when Prifinium is combined with Dezocine.
Levacetylmethadol The risk or severity of adverse effects can be increased when Prifinium is combined with Levacetylmethadol.
Methadyl acetate The risk or severity of adverse effects can be increased when Prifinium is combined with Methadyl acetate.
Dihydroetorphine The risk or severity of adverse effects can be increased when Prifinium is combined with Dihydroetorphine.
Diamorphine The risk or severity of adverse effects can be increased when Prifinium is combined with Diamorphine.
Ethylmorphine The risk or severity of adverse effects can be increased when Prifinium is combined with Ethylmorphine.
Etorphine The risk or severity of adverse effects can be increased when Prifinium is combined with Etorphine.
Dextromoramide The risk or severity of adverse effects can be increased when Prifinium is combined with Dextromoramide.
Desomorphine The risk or severity of adverse effects can be increased when Prifinium is combined with Desomorphine.
Carfentanil The risk or severity of adverse effects can be increased when Prifinium is combined with Carfentanil.
Dihydrocodeine The risk or severity of adverse effects can be increased when Prifinium is combined with Dihydrocodeine.
Alphacetylmethadol The risk or severity of adverse effects can be increased when Prifinium is combined with Alphacetylmethadol.
Dihydromorphine The risk or severity of adverse effects can be increased when Prifinium is combined with Dihydromorphine.
Tapentadol The risk or severity of urinary retention and constipation can be increased when Prifinium is combined with Tapentadol.
Ketobemidone The risk or severity of adverse effects can be increased when Prifinium is combined with Ketobemidone.
DPDPE The risk or severity of adverse effects can be increased when Prifinium is combined with DPDPE.
Lofentanil The risk or severity of adverse effects can be increased when Prifinium is combined with Lofentanil.
Opium The risk or severity of adverse effects can be increased when Prifinium is combined with Opium.
Normethadone The risk or severity of adverse effects can be increased when Prifinium is combined with Normethadone.
Piritramide The risk or severity of adverse effects can be increased when Prifinium is combined with Piritramide.
Alphaprodine The risk or severity of adverse effects can be increased when Prifinium is combined with Alphaprodine.
Nicomorphine The risk or severity of adverse effects can be increased when Prifinium is combined with Nicomorphine.
Meptazinol The risk or severity of adverse effects can be increased when Prifinium is combined with Meptazinol.
Phenoperidine The risk or severity of adverse effects can be increased when Prifinium is combined with Phenoperidine.
Phenazocine The risk or severity of adverse effects can be increased when Prifinium is combined with Phenazocine.
Tilidine The risk or severity of adverse effects can be increased when Prifinium is combined with Tilidine.
Carfentanil, C-11 The risk or severity of adverse effects can be increased when Prifinium is combined with Carfentanil, C-11.
Benzhydrocodone The risk or severity of adverse effects can be increased when Prifinium is combined with Benzhydrocodone.
Naloxegol The risk or severity of adverse effects can be increased when Prifinium is combined with Naloxegol.
Trospium The risk or severity of adverse effects can be increased when Trospium is combined with Prifinium.
Oxyphenonium The risk or severity of adverse effects can be increased when Oxyphenonium is combined with Prifinium.
Benzatropine The risk or severity of adverse effects can be increased when Benzatropine is combined with Prifinium.
Disopyramide The risk or severity of adverse effects can be increased when Disopyramide is combined with Prifinium.
Metixene The risk or severity of adverse effects can be increased when Metixene is combined with Prifinium.
Terfenadine The risk or severity of adverse effects can be increased when Terfenadine is combined with Prifinium.
Buclizine The risk or severity of adverse effects can be increased when Buclizine is combined with Prifinium.
Trihexyphenidyl The risk or severity of adverse effects can be increased when Trihexyphenidyl is combined with Prifinium.
Oxyphencyclimine The risk or severity of adverse effects can be increased when Oxyphencyclimine is combined with Prifinium.
Procyclidine The risk or severity of adverse effects can be increased when Procyclidine is combined with Prifinium.
Hyoscyamine The risk or severity of adverse effects can be increased when Hyoscyamine is combined with Prifinium.
Methscopolamine bromide The risk or severity of adverse effects can be increased when Methscopolamine bromide is combined with Prifinium.
Darifenacin The risk or severity of adverse effects can be increased when Darifenacin is combined with Prifinium.
Tridihexethyl The risk or severity of adverse effects can be increased when Tridihexethyl is combined with Prifinium.
Anisotropine methylbromide The risk or severity of adverse effects can be increased when Anisotropine methylbromide is combined with Prifinium.
Atropine The risk or severity of adverse effects can be increased when Atropine is combined with Prifinium.
Nicardipine The risk or severity of adverse effects can be increased when Nicardipine is combined with Prifinium.
Mecamylamine The risk or severity of adverse effects can be increased when Mecamylamine is combined with Prifinium.
Pirenzepine The risk or severity of adverse effects can be increased when Pirenzepine is combined with Prifinium.
Homatropine methylbromide The risk or severity of adverse effects can be increased when Homatropine methylbromide is combined with Prifinium.
Benzquinamide The risk or severity of adverse effects can be increased when Benzquinamide is combined with Prifinium.
Propantheline The risk or severity of adverse effects can be increased when Propantheline is combined with Prifinium.
Dicyclomine The risk or severity of adverse effects can be increased when Dicyclomine is combined with Prifinium.
Tropicamide The risk or severity of adverse effects can be increased when Tropicamide is combined with Prifinium.
Cocaine The risk or severity of adverse effects can be increased when Cocaine is combined with Prifinium.
Quinidine The risk or severity of adverse effects can be increased when Quinidine is combined with Prifinium.
Amantadine The risk or severity of adverse effects can be increased when Amantadine is combined with Prifinium.
Methantheline The risk or severity of adverse effects can be increased when Methantheline is combined with Prifinium.
Cycrimine The risk or severity of adverse effects can be increased when Cycrimine is combined with Prifinium.
Cyclopentolate The risk or severity of adverse effects can be increased when Cyclopentolate is combined with Prifinium.
Tolterodine The risk or severity of adverse effects can be increased when Tolterodine is combined with Prifinium.
Oxybutynin The risk or severity of adverse effects can be increased when Oxybutynin is combined with Prifinium.
Pentolinium The risk or severity of adverse effects can be increased when Pentolinium is combined with Prifinium.
Trimethaphan The risk or severity of adverse effects can be increased when Trimethaphan is combined with Prifinium.

Target Protein

Muscarinic acetylcholine receptor M5 CHRM5

Referensi & Sumber

Artikel (PubMed)
  • PMID: 2859117
    Sasaki D, Suzuki A, Yoshida Y, Okamoto K, Ohmi T, Takahashi S, Yoshida S, Fukushi K, Higuchi K: Treatment of irritable bowel syndrome with prifinium bromide. Clin Ther. 1985;7(2):190-8.

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