Calcitonin is a polypeptide hormone secreted by the parafollicular cells of the thyroid gland in mammals. It inhibits bone resorption and lowers both serum and urinary calcium concentrations. Human calcitonin is available only in very small quantities but has been used in some studies. The first commercially available preparation in Britain was porcine calcitonin (brand name Calcitare).
Fitur visualisasi ini dikembangkan menggunakan pendekatan Graph Theory untuk memetakan hubungan polifarmasi dan molekuler. Entitas (Obat, Target, Gen) direpresentasikan sebagai Simpul (Nodes), sedangkan hubungan biologisnya sebagai Sisi (Edges).
drugbank-id dan name pada skema XML DrugBank.targets/target yang memuat polipeptida sasaran.gene-name dan varian snp-effects.Tata letak grafik menggunakan algoritma Force-Directed Graph (Barnes-Hut). Model fisika ini menerapkan gaya tolak-menolak antar simpul (Gravitasi: -3000) agar tidak tumpang tindih, serta gaya pegas (Spring: 0.04) pada garis penghubung untuk fleksibilitas interaksi.
| Pamidronic acid | The risk or severity of hypocalcemia can be increased when Calcitonin porcine is combined with Pamidronic acid. |
| Zoledronic acid | The risk or severity of hypocalcemia can be increased when Calcitonin porcine is combined with Zoledronic acid. |
| Alendronic acid | The risk or severity of hypocalcemia can be increased when Calcitonin porcine is combined with Alendronic acid. |
| Ibandronate | The risk or severity of hypocalcemia can be increased when Calcitonin porcine is combined with Ibandronate. |
| Clodronic acid | The risk or severity of hypocalcemia can be increased when Calcitonin porcine is combined with Clodronic acid. |
| Risedronic acid | The risk or severity of hypocalcemia can be increased when Calcitonin porcine is combined with Risedronic acid. |
| Etidronic acid | The risk or severity of hypocalcemia can be increased when Calcitonin porcine is combined with Etidronic acid. |
| Tiludronic acid | The risk or severity of hypocalcemia can be increased when Calcitonin porcine is combined with Tiludronic acid. |
| Incadronic acid | The risk or severity of hypocalcemia can be increased when Calcitonin porcine is combined with Incadronic acid. |
| Lithium citrate | Calcitonin porcine may increase the excretion rate of Lithium citrate which could result in a lower serum level and potentially a reduction in efficacy. |
| Lithium carbonate | Calcitonin porcine may increase the excretion rate of Lithium carbonate which could result in a lower serum level and potentially a reduction in efficacy. |
| Lithium hydroxide | Calcitonin porcine may increase the excretion rate of Lithium hydroxide which could result in a lower serum level and potentially a reduction in efficacy. |