Zofenopril

DB13166

small molecule approved

Deskripsi

Zofenopril is employed as both a cardioprotective and anti-hypertensive agent. It is an angiotensin-converting enzyme (ACE) inhibitor.

Struktur Molekul 2D

Berat 429.55
Wujud solid

Peta Jejaring Molekuler
Legenda: ObatTargetGenEnzim(Panah → menunjukkan arah efek / relasi)TransporterCarrier

Profil Farmakokinetik

Waktu Paruh (Half-Life) -
Volume Distribusi -
Klirens (Clearance) -

Absorpsi

Data absorpsi tidak tersedia.

Metabolisme

Data metabolisme tidak tersedia.

Rute Eliminasi

Data eliminasi belum tersedia.

Interaksi Obat

833 Data
Alfuzosin Alfuzosin may increase the hypotensive activities of Zofenopril.
Amifostine Zofenopril may increase the hypotensive activities of Amifostine.
Diazoxide Diazoxide may increase the hypotensive activities of Zofenopril.
Methylphenidate Methylphenidate may decrease the antihypertensive activities of Zofenopril.
Dexmethylphenidate Dexmethylphenidate may decrease the antihypertensive activities of Zofenopril.
Obinutuzumab Zofenopril may increase the hypotensive activities of Obinutuzumab.
Pentoxifylline Pentoxifylline may increase the hypotensive activities of Zofenopril.
Rituximab Zofenopril may increase the hypotensive activities of Rituximab.
Desmopressin Desmopressin may decrease the antihypertensive activities of Zofenopril.
Phentermine Phentermine may decrease the antihypertensive activities of Zofenopril.
Midodrine Midodrine may decrease the antihypertensive activities of Zofenopril.
Eletriptan Eletriptan may decrease the antihypertensive activities of Zofenopril.
Isoetharine Isoetharine may decrease the antihypertensive activities of Zofenopril.
Methysergide Methysergide may decrease the antihypertensive activities of Zofenopril.
Cabergoline Cabergoline may decrease the antihypertensive activities of Zofenopril.
Atomoxetine Atomoxetine may decrease the antihypertensive activities of Zofenopril.
Etomidate Etomidate may decrease the antihypertensive activities of Zofenopril.
Zolmitriptan Zolmitriptan may decrease the antihypertensive activities of Zofenopril.
Dihydroergotamine Dihydroergotamine may decrease the antihypertensive activities of Zofenopril.
Amitriptyline Amitriptyline may decrease the antihypertensive activities of Zofenopril.
Protriptyline Protriptyline may decrease the antihypertensive activities of Zofenopril.
Methylergometrine Methylergometrine may decrease the antihypertensive activities of Zofenopril.
Norepinephrine Norepinephrine may decrease the antihypertensive activities of Zofenopril.
Mirtazapine Mirtazapine may decrease the antihypertensive activities of Zofenopril.
Phenylephrine Phenylephrine may decrease the antihypertensive activities of Zofenopril.
Phenylpropanolamine Phenylpropanolamine may decrease the antihypertensive activities of Zofenopril.
Promazine Promazine may decrease the antihypertensive activities of Zofenopril.
Droperidol Droperidol may decrease the antihypertensive activities of Zofenopril.
Buspirone Buspirone may decrease the antihypertensive activities of Zofenopril.
Nortriptyline Nortriptyline may decrease the antihypertensive activities of Zofenopril.
Amoxapine Amoxapine may decrease the antihypertensive activities of Zofenopril.
Doxapram Doxapram may decrease the antihypertensive activities of Zofenopril.
Atropine Atropine may decrease the antihypertensive activities of Zofenopril.
Lisuride Lisuride may decrease the antihypertensive activities of Zofenopril.
Metaraminol Metaraminol may decrease the antihypertensive activities of Zofenopril.
Trazodone Trazodone may decrease the antihypertensive activities of Zofenopril.
Epinephrine Epinephrine may decrease the antihypertensive activities of Zofenopril.
Sumatriptan Sumatriptan may decrease the antihypertensive activities of Zofenopril.
Ergotamine Ergotamine may decrease the antihypertensive activities of Zofenopril.
Nicergoline Nicergoline may decrease the antihypertensive activities of Zofenopril.
Methoxamine Methoxamine may decrease the antihypertensive activities of Zofenopril.
Trimipramine Trimipramine may decrease the antihypertensive activities of Zofenopril.
Risperidone Risperidone may decrease the antihypertensive activities of Zofenopril.
Propiomazine Propiomazine may decrease the antihypertensive activities of Zofenopril.
Alfentanil Alfentanil may decrease the antihypertensive activities of Zofenopril.
Fentanyl Fentanyl may decrease the antihypertensive activities of Zofenopril.
Orciprenaline Orciprenaline may decrease the antihypertensive activities of Zofenopril.
Phenmetrazine Phenmetrazine may decrease the antihypertensive activities of Zofenopril.
Trifluoperazine Trifluoperazine may decrease the antihypertensive activities of Zofenopril.
Dobutamine Dobutamine may decrease the antihypertensive activities of Zofenopril.
Pseudoephedrine Pseudoephedrine may decrease the antihypertensive activities of Zofenopril.
Benzphetamine Benzphetamine may decrease the antihypertensive activities of Zofenopril.
Ritodrine Ritodrine may decrease the antihypertensive activities of Zofenopril.
Terbutaline Terbutaline may decrease the antihypertensive activities of Zofenopril.
Flupentixol Flupentixol may decrease the antihypertensive activities of Zofenopril.
Bitolterol Bitolterol may decrease the antihypertensive activities of Zofenopril.
Quinidine Quinidine may decrease the antihypertensive activities of Zofenopril.
Almotriptan Almotriptan may decrease the antihypertensive activities of Zofenopril.
Diethylpropion Diethylpropion may decrease the antihypertensive activities of Zofenopril.
Salmeterol Salmeterol may decrease the antihypertensive activities of Zofenopril.
Naratriptan Naratriptan may decrease the antihypertensive activities of Zofenopril.
Rizatriptan Rizatriptan may decrease the antihypertensive activities of Zofenopril.
Formoterol Formoterol may decrease the antihypertensive activities of Zofenopril.
Dopamine Dopamine may decrease the antihypertensive activities of Zofenopril.
Frovatriptan Frovatriptan may decrease the antihypertensive activities of Zofenopril.
Albuterol Salbutamol may decrease the antihypertensive activities of Zofenopril.
Methoxyflurane Methoxyflurane may decrease the antihypertensive activities of Zofenopril.
Ergoloid mesylate Ergoloid mesylate may decrease the antihypertensive activities of Zofenopril.
Isoprenaline Isoprenaline may decrease the antihypertensive activities of Zofenopril.
Arbutamine Arbutamine may decrease the antihypertensive activities of Zofenopril.
Dutasteride Dutasteride may decrease the antihypertensive activities of Zofenopril.
Doxepin Doxepin may decrease the antihypertensive activities of Zofenopril.
Nefazodone Nefazodone may decrease the antihypertensive activities of Zofenopril.
Desipramine Desipramine may decrease the antihypertensive activities of Zofenopril.
Pergolide Pergolide may decrease the antihypertensive activities of Zofenopril.
Finasteride Finasteride may decrease the antihypertensive activities of Zofenopril.
Ergometrine Ergometrine may decrease the antihypertensive activities of Zofenopril.
Lisdexamfetamine Lisdexamfetamine may decrease the antihypertensive activities of Zofenopril.
Paliperidone Paliperidone may decrease the antihypertensive activities of Zofenopril.
Arformoterol Arformoterol may decrease the antihypertensive activities of Zofenopril.
Fenoterol Fenoterol may decrease the antihypertensive activities of Zofenopril.
Pirbuterol Pirbuterol may decrease the antihypertensive activities of Zofenopril.
Ephedra sinica root Ephedra sinica root may decrease the antihypertensive activities of Zofenopril.
Ephedrine Ephedrine may decrease the antihypertensive activities of Zofenopril.
Mephentermine Mephentermine may decrease the antihypertensive activities of Zofenopril.
Procaterol Procaterol may decrease the antihypertensive activities of Zofenopril.
Yohimbine Yohimbine may decrease the antihypertensive activities of Zofenopril.
Methotrimeprazine Methotrimeprazine may decrease the antihypertensive activities of Zofenopril.
Clenbuterol Clenbuterol may decrease the antihypertensive activities of Zofenopril.
Bambuterol Bambuterol may decrease the antihypertensive activities of Zofenopril.
MMDA MMDA may decrease the antihypertensive activities of Zofenopril.
Midomafetamine Midomafetamine may decrease the antihypertensive activities of Zofenopril.
2,5-Dimethoxy-4-ethylamphetamine 2,5-Dimethoxy-4-ethylamphetamine may decrease the antihypertensive activities of Zofenopril.
4-Methoxyamphetamine 4-Methoxyamphetamine may decrease the antihypertensive activities of Zofenopril.
4-Bromo-2,5-dimethoxyamphetamine 4-Bromo-2,5-dimethoxyamphetamine may decrease the antihypertensive activities of Zofenopril.
Tenamfetamine Tenamfetamine may decrease the antihypertensive activities of Zofenopril.
Chlorphentermine Chlorphentermine may decrease the antihypertensive activities of Zofenopril.
Dextroamphetamine Dextroamphetamine may decrease the antihypertensive activities of Zofenopril.
Metamfetamine Metamfetamine may decrease the antihypertensive activities of Zofenopril.
Phendimetrazine Phendimetrazine may decrease the antihypertensive activities of Zofenopril.

Target Protein

Angiotensin-converting enzyme ACE

Referensi & Sumber

Artikel (PubMed)
  • PMID: 18046976
    Nilsson P: Antihypertensive efficacy of zofenopril compared with atenolol in patients with mild to moderate hypertension. Blood Press Suppl. 2007 Oct;2:25-30.
  • PMID: 18046974
    Mallion JM: An evaluation of the initial and long-term antihypertensive efficacy of zofenopril compared with enalapril in mild to moderate hypertension. Blood Press Suppl. 2007 Oct;2:13-8.

Contoh Produk & Brand

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Sekuens Gen/Protein (FASTA)

Sekuens dimuat saat dibutuhkan agar halaman tetap ringan.
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