1alpha-Hydroxyvitamin D5

DB13097

small molecule investigational

Deskripsi

1alpha-Hydroxyvitamin D5 (CARD-024) has been used in trials studying the treatment of Drug Safety and Heart; Disease, Activity.

Struktur Molekul 2D

Berat 428.701
Wujud -

Peta Jejaring Molekuler
Legenda: ObatTargetGenEnzim(Panah → menunjukkan arah efek / relasi)TransporterCarrier

Profil Farmakokinetik

Waktu Paruh (Half-Life) -
Volume Distribusi -
Klirens (Clearance) -

Absorpsi

Data absorpsi tidak tersedia.

Metabolisme

Data metabolisme tidak tersedia.

Rute Eliminasi

Data eliminasi belum tersedia.

Interaksi Obat

157 Data
Aluminum hydroxide The serum concentration of Aluminum hydroxide can be increased when it is combined with 1alpha-Hydroxyvitamin D5.
Danazol Danazol may increase the hypercalcemic activities of 1alpha-Hydroxyvitamin D5.
Sucralfate The serum concentration of Sucralfate can be increased when it is combined with 1alpha-Hydroxyvitamin D5.
Orlistat Orlistat can cause a decrease in the absorption of 1alpha-Hydroxyvitamin D5 resulting in a reduced serum concentration and potentially a decrease in efficacy.
Magnesium sulfate The serum concentration of Magnesium sulfate can be increased when it is combined with 1alpha-Hydroxyvitamin D5.
Magnesium oxide The serum concentration of Magnesium oxide can be increased when it is combined with 1alpha-Hydroxyvitamin D5.
Magnesium salicylate The serum concentration of Magnesium salicylate can be increased when it is combined with 1alpha-Hydroxyvitamin D5.
Magaldrate The serum concentration of Magaldrate can be increased when it is combined with 1alpha-Hydroxyvitamin D5.
Magnesium hydroxide The serum concentration of Magnesium hydroxide can be increased when it is combined with 1alpha-Hydroxyvitamin D5.
Magnesium trisilicate The serum concentration of Magnesium trisilicate can be increased when it is combined with 1alpha-Hydroxyvitamin D5.
Magnesium chloride The serum concentration of Magnesium chloride can be increased when it is combined with 1alpha-Hydroxyvitamin D5.
Magnesium carbonate The serum concentration of Magnesium carbonate can be increased when it is combined with 1alpha-Hydroxyvitamin D5.
Talc The serum concentration of Talc can be increased when it is combined with 1alpha-Hydroxyvitamin D5.
Magnesium citrate The serum concentration of Magnesium citrate can be increased when it is combined with 1alpha-Hydroxyvitamin D5.
Magnesium silicate The serum concentration of Magnesium silicate can be increased when it is combined with 1alpha-Hydroxyvitamin D5.
Hydrotalcite The serum concentration of Hydrotalcite can be increased when it is combined with 1alpha-Hydroxyvitamin D5.
Magnesium aspartate The serum concentration of Magnesium aspartate can be increased when it is combined with 1alpha-Hydroxyvitamin D5.
Magnesium peroxide The serum concentration of Magnesium peroxide can be increased when it is combined with 1alpha-Hydroxyvitamin D5.
Magnesium gluconate The serum concentration of Magnesium gluconate can be increased when it is combined with 1alpha-Hydroxyvitamin D5.
Magnesium orotate The serum concentration of Magnesium orotate can be increased when it is combined with 1alpha-Hydroxyvitamin D5.
Magnesium The serum concentration of Magnesium can be increased when it is combined with 1alpha-Hydroxyvitamin D5.
Magnesium levulinate The serum concentration of Magnesium levulinate can be increased when it is combined with 1alpha-Hydroxyvitamin D5.
Magnesium lactate The serum concentration of Magnesium lactate can be increased when it is combined with 1alpha-Hydroxyvitamin D5.
Digoxin The risk or severity of ventricular arrhythmias and Cardiac Arrhythmia can be increased when 1alpha-Hydroxyvitamin D5 is combined with Digoxin.
Acetyldigitoxin The risk or severity of ventricular arrhythmias and Cardiac Arrhythmia can be increased when 1alpha-Hydroxyvitamin D5 is combined with Acetyldigitoxin.
Deslanoside The risk or severity of ventricular arrhythmias and Cardiac Arrhythmia can be increased when 1alpha-Hydroxyvitamin D5 is combined with Deslanoside.
Ouabain The risk or severity of ventricular arrhythmias and Cardiac Arrhythmia can be increased when 1alpha-Hydroxyvitamin D5 is combined with Ouabain.
Digitoxin The risk or severity of ventricular arrhythmias and Cardiac Arrhythmia can be increased when 1alpha-Hydroxyvitamin D5 is combined with Digitoxin.
Oleandrin The risk or severity of ventricular arrhythmias and Cardiac Arrhythmia can be increased when 1alpha-Hydroxyvitamin D5 is combined with Oleandrin.
Cymarin The risk or severity of ventricular arrhythmias and Cardiac Arrhythmia can be increased when 1alpha-Hydroxyvitamin D5 is combined with Cymarin.
Proscillaridin The risk or severity of ventricular arrhythmias and Cardiac Arrhythmia can be increased when 1alpha-Hydroxyvitamin D5 is combined with Proscillaridin.
Metildigoxin The risk or severity of ventricular arrhythmias and Cardiac Arrhythmia can be increased when 1alpha-Hydroxyvitamin D5 is combined with Metildigoxin.
Lanatoside C The risk or severity of ventricular arrhythmias and Cardiac Arrhythmia can be increased when 1alpha-Hydroxyvitamin D5 is combined with Lanatoside C.
Gitoformate The risk or severity of ventricular arrhythmias and Cardiac Arrhythmia can be increased when 1alpha-Hydroxyvitamin D5 is combined with Gitoformate.
Acetyldigoxin The risk or severity of ventricular arrhythmias and Cardiac Arrhythmia can be increased when 1alpha-Hydroxyvitamin D5 is combined with Acetyldigoxin.
Peruvoside The risk or severity of ventricular arrhythmias and Cardiac Arrhythmia can be increased when 1alpha-Hydroxyvitamin D5 is combined with Peruvoside.
Mineral oil Mineral oil can cause a decrease in the absorption of 1alpha-Hydroxyvitamin D5 resulting in a reduced serum concentration and potentially a decrease in efficacy.
Methyclothiazide The risk or severity of hypercalcemia can be increased when Methyclothiazide is combined with 1alpha-Hydroxyvitamin D5.
Bendroflumethiazide The risk or severity of hypercalcemia can be increased when Bendroflumethiazide is combined with 1alpha-Hydroxyvitamin D5.
Benzthiazide The risk or severity of hypercalcemia can be increased when Benzthiazide is combined with 1alpha-Hydroxyvitamin D5.
Cyclothiazide The risk or severity of hypercalcemia can be increased when Cyclothiazide is combined with 1alpha-Hydroxyvitamin D5.
Hydroflumethiazide The risk or severity of hypercalcemia can be increased when Hydroflumethiazide is combined with 1alpha-Hydroxyvitamin D5.
Chlorothiazide The risk or severity of hypercalcemia can be increased when Chlorothiazide is combined with 1alpha-Hydroxyvitamin D5.
Hydrochlorothiazide The risk or severity of hypercalcemia can be increased when Hydrochlorothiazide is combined with 1alpha-Hydroxyvitamin D5.
Trichlormethiazide The risk or severity of hypercalcemia can be increased when Trichlormethiazide is combined with 1alpha-Hydroxyvitamin D5.
Polythiazide The risk or severity of hypercalcemia can be increased when Polythiazide is combined with 1alpha-Hydroxyvitamin D5.
Mebutizide The risk or severity of hypercalcemia can be increased when Mebutizide is combined with 1alpha-Hydroxyvitamin D5.
Cyclopenthiazide The risk or severity of hypercalcemia can be increased when Cyclopenthiazide is combined with 1alpha-Hydroxyvitamin D5.
Buthiazide The risk or severity of hypercalcemia can be increased when Buthiazide is combined with 1alpha-Hydroxyvitamin D5.
Calcitriol The risk or severity of adverse effects can be increased when Calcitriol is combined with 1alpha-Hydroxyvitamin D5.
Calcifediol The risk or severity of adverse effects can be increased when Calcifediol is combined with 1alpha-Hydroxyvitamin D5.
Ergocalciferol The risk or severity of adverse effects can be increased when Ergocalciferol is combined with 1alpha-Hydroxyvitamin D5.
Cholecalciferol The risk or severity of adverse effects can be increased when Cholecalciferol is combined with 1alpha-Hydroxyvitamin D5.
Paricalcitol The risk or severity of adverse effects can be increased when Paricalcitol is combined with 1alpha-Hydroxyvitamin D5.
Dihydrotachysterol The risk or severity of adverse effects can be increased when Dihydrotachysterol is combined with 1alpha-Hydroxyvitamin D5.
Alfacalcidol The risk or severity of adverse effects can be increased when Alfacalcidol is combined with 1alpha-Hydroxyvitamin D5.
Seocalcitol The risk or severity of adverse effects can be increased when Seocalcitol is combined with 1alpha-Hydroxyvitamin D5.
Inecalcitol The risk or severity of adverse effects can be increased when Inecalcitol is combined with 1alpha-Hydroxyvitamin D5.
Becocalcidiol The risk or severity of adverse effects can be increased when Becocalcidiol is combined with 1alpha-Hydroxyvitamin D5.
Eldecalcitol The risk or severity of adverse effects can be increased when Eldecalcitol is combined with 1alpha-Hydroxyvitamin D5.
1alpha,24S-Dihydroxyvitamin D2 The risk or severity of adverse effects can be increased when 1alpha,24S-Dihydroxyvitamin D2 is combined with 1alpha-Hydroxyvitamin D5.
Elocalcitol The risk or severity of adverse effects can be increased when Elocalcitol is combined with 1alpha-Hydroxyvitamin D5.
Maxacalcitol The risk or severity of adverse effects can be increased when Maxacalcitol is combined with 1alpha-Hydroxyvitamin D5.
Doxercalciferol The risk or severity of adverse effects can be increased when Doxercalciferol is combined with 1alpha-Hydroxyvitamin D5.
Vitamin D The risk or severity of adverse effects can be increased when Vitamin D is combined with 1alpha-Hydroxyvitamin D5.
Previtamin D(3) The risk or severity of adverse effects can be increased when 1alpha-Hydroxyvitamin D5 is combined with Previtamin D(3).
Calcium acetate The risk or severity of adverse effects can be increased when 1alpha-Hydroxyvitamin D5 is combined with Calcium acetate.
Calcium glucoheptonate The risk or severity of adverse effects can be increased when 1alpha-Hydroxyvitamin D5 is combined with Calcium glucoheptonate.
Calcium chloride The risk or severity of adverse effects can be increased when 1alpha-Hydroxyvitamin D5 is combined with Calcium chloride.
Calcium The risk or severity of adverse effects can be increased when 1alpha-Hydroxyvitamin D5 is combined with Calcium.
Calcium carbonate The risk or severity of adverse effects can be increased when 1alpha-Hydroxyvitamin D5 is combined with Calcium carbonate.
Calcium citrate The risk or severity of adverse effects can be increased when 1alpha-Hydroxyvitamin D5 is combined with Calcium citrate.
Calcium gluconate The risk or severity of adverse effects can be increased when 1alpha-Hydroxyvitamin D5 is combined with Calcium gluconate.
Calcium Phosphate The risk or severity of adverse effects can be increased when 1alpha-Hydroxyvitamin D5 is combined with Calcium Phosphate.
Calcium glubionate anhydrous The risk or severity of adverse effects can be increased when 1alpha-Hydroxyvitamin D5 is combined with Calcium glubionate anhydrous.
Calcium lactate The risk or severity of adverse effects can be increased when 1alpha-Hydroxyvitamin D5 is combined with Calcium lactate.
Calcium lactate gluconate The risk or severity of adverse effects can be increased when 1alpha-Hydroxyvitamin D5 is combined with Calcium lactate gluconate.
Calcium pangamate The risk or severity of adverse effects can be increased when 1alpha-Hydroxyvitamin D5 is combined with Calcium pangamate.
Calcium levulinate The risk or severity of adverse effects can be increased when 1alpha-Hydroxyvitamin D5 is combined with Calcium levulinate.
Calcium cation The risk or severity of adverse effects can be increased when 1alpha-Hydroxyvitamin D5 is combined with Calcium cation.
Calcium polycarbophil The risk or severity of adverse effects can be increased when 1alpha-Hydroxyvitamin D5 is combined with Calcium polycarbophil.
Colestipol The serum concentration of 1alpha-Hydroxyvitamin D5 can be decreased when it is combined with Colestipol.
Sevelamer The serum concentration of 1alpha-Hydroxyvitamin D5 can be decreased when it is combined with Sevelamer.
Colesevelam The serum concentration of 1alpha-Hydroxyvitamin D5 can be decreased when it is combined with Colesevelam.
Cholestyramine The serum concentration of 1alpha-Hydroxyvitamin D5 can be decreased when it is combined with Cholestyramine.
Flunisolide The therapeutic efficacy of 1alpha-Hydroxyvitamin D5 can be decreased when used in combination with Flunisolide.
Beclomethasone dipropionate The therapeutic efficacy of 1alpha-Hydroxyvitamin D5 can be decreased when used in combination with Beclomethasone dipropionate.
Betamethasone The therapeutic efficacy of 1alpha-Hydroxyvitamin D5 can be decreased when used in combination with Betamethasone.
Fluticasone propionate The therapeutic efficacy of 1alpha-Hydroxyvitamin D5 can be decreased when used in combination with Fluticasone propionate.
Fluocinolone acetonide The therapeutic efficacy of 1alpha-Hydroxyvitamin D5 can be decreased when used in combination with Fluocinolone acetonide.
Triamcinolone The therapeutic efficacy of 1alpha-Hydroxyvitamin D5 can be decreased when used in combination with Triamcinolone.
Prednisone The therapeutic efficacy of 1alpha-Hydroxyvitamin D5 can be decreased when used in combination with Prednisone.
Fludrocortisone The therapeutic efficacy of 1alpha-Hydroxyvitamin D5 can be decreased when used in combination with Fludrocortisone.
Hydrocortisone The therapeutic efficacy of 1alpha-Hydroxyvitamin D5 can be decreased when used in combination with Hydrocortisone.
Prednisolone The therapeutic efficacy of 1alpha-Hydroxyvitamin D5 can be decreased when used in combination with Prednisolone.
Methylprednisolone The therapeutic efficacy of 1alpha-Hydroxyvitamin D5 can be decreased when used in combination with Methylprednisolone.
Trilostane The therapeutic efficacy of 1alpha-Hydroxyvitamin D5 can be decreased when used in combination with Trilostane.
Budesonide The therapeutic efficacy of 1alpha-Hydroxyvitamin D5 can be decreased when used in combination with Budesonide.
Dexamethasone The therapeutic efficacy of 1alpha-Hydroxyvitamin D5 can be decreased when used in combination with Dexamethasone.
Corticotropin The therapeutic efficacy of 1alpha-Hydroxyvitamin D5 can be decreased when used in combination with Corticotropin.

Target Protein

Renin REN

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