Delpazolid

DB13077

small molecule investigational

Deskripsi

Delpazolid (LCB01-0371) is under investigation in clinical trial NCT01554995 (A Clinical Study, Randomized, Double-blind, Placebo-controlled, Single Dose Study).

Struktur Molekul 2D

Berat 308.313
Wujud -

Peta Jejaring Molekuler
Legenda: ObatTargetGenEnzim(Panah → menunjukkan arah efek / relasi)TransporterCarrier

Profil Farmakokinetik

Waktu Paruh (Half-Life) -
Volume Distribusi -
Klirens (Clearance) -

Absorpsi

Data absorpsi tidak tersedia.

Metabolisme

Data metabolisme tidak tersedia.

Rute Eliminasi

Data eliminasi belum tersedia.

Interaksi Obat

55 Data
Picosulfuric acid The therapeutic efficacy of Picosulfuric acid can be decreased when used in combination with LCB01-0371.
BCG vaccine The therapeutic efficacy of BCG vaccine can be decreased when used in combination with LCB01-0371.
Typhoid vaccine The therapeutic efficacy of Typhoid vaccine can be decreased when used in combination with LCB01-0371.
Dicoumarol The risk or severity of bleeding can be increased when LCB01-0371 is combined with Dicoumarol.
Phenindione The risk or severity of bleeding can be increased when LCB01-0371 is combined with Phenindione.
Warfarin The risk or severity of bleeding can be increased when LCB01-0371 is combined with Warfarin.
Phenprocoumon The risk or severity of bleeding can be increased when LCB01-0371 is combined with Phenprocoumon.
Acenocoumarol The risk or severity of bleeding can be increased when LCB01-0371 is combined with Acenocoumarol.
4-hydroxycoumarin The risk or severity of bleeding can be increased when LCB01-0371 is combined with 4-hydroxycoumarin.
Coumarin The risk or severity of bleeding can be increased when LCB01-0371 is combined with Coumarin.
(R)-warfarin The risk or severity of bleeding can be increased when LCB01-0371 is combined with (R)-warfarin.
Ethyl biscoumacetate The risk or severity of bleeding can be increased when LCB01-0371 is combined with Ethyl biscoumacetate.
Fluindione The risk or severity of bleeding can be increased when LCB01-0371 is combined with Fluindione.
Clorindione The risk or severity of bleeding can be increased when LCB01-0371 is combined with Clorindione.
Diphenadione The risk or severity of bleeding can be increased when LCB01-0371 is combined with Diphenadione.
Tioclomarol The risk or severity of bleeding can be increased when LCB01-0371 is combined with Tioclomarol.
(S)-Warfarin The risk or severity of bleeding can be increased when LCB01-0371 is combined with (S)-Warfarin.
Lactulose The therapeutic efficacy of Lactulose can be decreased when used in combination with LCB01-0371.
Vibrio cholerae CVD 103-HgR strain live antigen The therapeutic efficacy of Vibrio cholerae CVD 103-HgR strain live antigen can be decreased when used in combination with LCB01-0371.
Estetrol The therapeutic efficacy of Estetrol can be decreased when used in combination with LCB01-0371.
Lidocaine The risk or severity of methemoglobinemia can be increased when LCB01-0371 is combined with Lidocaine.
Ropivacaine The risk or severity of methemoglobinemia can be increased when LCB01-0371 is combined with Ropivacaine.
Bupivacaine The risk or severity of methemoglobinemia can be increased when LCB01-0371 is combined with Bupivacaine.
Cinchocaine The risk or severity of methemoglobinemia can be increased when LCB01-0371 is combined with Cinchocaine.
Dyclonine The risk or severity of methemoglobinemia can be increased when LCB01-0371 is combined with Dyclonine.
Procaine The risk or severity of methemoglobinemia can be increased when LCB01-0371 is combined with Procaine.
Prilocaine The risk or severity of methemoglobinemia can be increased when LCB01-0371 is combined with Prilocaine.
Proparacaine The risk or severity of methemoglobinemia can be increased when LCB01-0371 is combined with Proparacaine.
Meloxicam The risk or severity of methemoglobinemia can be increased when LCB01-0371 is combined with Meloxicam.
Oxybuprocaine The risk or severity of methemoglobinemia can be increased when LCB01-0371 is combined with Oxybuprocaine.
Cocaine The risk or severity of methemoglobinemia can be increased when LCB01-0371 is combined with Cocaine.
Mepivacaine The risk or severity of methemoglobinemia can be increased when LCB01-0371 is combined with Mepivacaine.
Levobupivacaine The risk or severity of methemoglobinemia can be increased when LCB01-0371 is combined with Levobupivacaine.
Diphenhydramine The risk or severity of methemoglobinemia can be increased when LCB01-0371 is combined with Diphenhydramine.
Benzocaine The risk or severity of methemoglobinemia can be increased when LCB01-0371 is combined with Benzocaine.
Chloroprocaine The risk or severity of methemoglobinemia can be increased when LCB01-0371 is combined with Chloroprocaine.
Phenol The risk or severity of methemoglobinemia can be increased when LCB01-0371 is combined with Phenol.
Tetrodotoxin The risk or severity of methemoglobinemia can be increased when LCB01-0371 is combined with Tetrodotoxin.
Benzyl alcohol The risk or severity of methemoglobinemia can be increased when LCB01-0371 is combined with Benzyl alcohol.
Capsaicin The risk or severity of methemoglobinemia can be increased when LCB01-0371 is combined with Capsaicin.
Etidocaine The risk or severity of methemoglobinemia can be increased when LCB01-0371 is combined with Etidocaine.
Articaine The risk or severity of methemoglobinemia can be increased when LCB01-0371 is combined with Articaine.
Tetracaine The risk or severity of methemoglobinemia can be increased when LCB01-0371 is combined with Tetracaine.
Propoxycaine The risk or severity of methemoglobinemia can be increased when LCB01-0371 is combined with Propoxycaine.
Pramocaine The risk or severity of methemoglobinemia can be increased when LCB01-0371 is combined with Pramocaine.
Butamben The risk or severity of methemoglobinemia can be increased when LCB01-0371 is combined with Butamben.
Butacaine The risk or severity of methemoglobinemia can be increased when LCB01-0371 is combined with Butacaine.
Oxetacaine The risk or severity of methemoglobinemia can be increased when LCB01-0371 is combined with Oxetacaine.
Ethyl chloride The risk or severity of methemoglobinemia can be increased when LCB01-0371 is combined with Ethyl chloride.
Butanilicaine The risk or severity of methemoglobinemia can be increased when LCB01-0371 is combined with Butanilicaine.
Metabutethamine The risk or severity of methemoglobinemia can be increased when LCB01-0371 is combined with Metabutethamine.
Quinisocaine The risk or severity of methemoglobinemia can be increased when LCB01-0371 is combined with Quinisocaine.
Cisatracurium LCB01-0371 may increase the neuromuscular blocking activities of Cisatracurium.
Ambroxol The risk or severity of methemoglobinemia can be increased when LCB01-0371 is combined with Ambroxol.
Fecal microbiota The therapeutic efficacy of Fecal microbiota can be decreased when used in combination with Delpazolid.

Referensi & Sumber

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