9-(N-methyl-L-isoleucine)-cyclosporin A

DB13068

small molecule investigational

Deskripsi

9-(N-methyl-L-isoleucine)-cyclosporin A (NIM811) has been used in trials studying the treatment of Chronic Hepatitis C Genotype-1 Relapse.

Struktur Molekul 2D

Berat 1202.635
Wujud -

Peta Jejaring Molekuler
Legenda: ObatTargetGenEnzim(Panah → menunjukkan arah efek / relasi)TransporterCarrier

Profil Farmakokinetik

Waktu Paruh (Half-Life) -
Volume Distribusi -
Klirens (Clearance) -

Absorpsi

Data absorpsi tidak tersedia.

Metabolisme

Data metabolisme tidak tersedia.

Rute Eliminasi

Data eliminasi belum tersedia.

Interaksi Obat

353 Data
Denosumab The risk or severity of adverse effects can be increased when Denosumab is combined with 9-(N-methyl-L-isoleucine)-cyclosporin A.
Etanercept The risk or severity of adverse effects can be increased when Etanercept is combined with 9-(N-methyl-L-isoleucine)-cyclosporin A.
Peginterferon alfa-2a The risk or severity of adverse effects can be increased when Peginterferon alfa-2a is combined with 9-(N-methyl-L-isoleucine)-cyclosporin A.
Interferon alfa-n1 The risk or severity of adverse effects can be increased when Interferon alfa-n1 is combined with 9-(N-methyl-L-isoleucine)-cyclosporin A.
Interferon alfa-n3 The risk or severity of adverse effects can be increased when Interferon alfa-n3 is combined with 9-(N-methyl-L-isoleucine)-cyclosporin A.
Peginterferon alfa-2b The risk or severity of adverse effects can be increased when Peginterferon alfa-2b is combined with 9-(N-methyl-L-isoleucine)-cyclosporin A.
Anakinra The risk or severity of adverse effects can be increased when Anakinra is combined with 9-(N-methyl-L-isoleucine)-cyclosporin A.
Interferon gamma-1b The risk or severity of adverse effects can be increased when Interferon gamma-1b is combined with 9-(N-methyl-L-isoleucine)-cyclosporin A.
Interferon alfa-2a The risk or severity of adverse effects can be increased when Interferon alfa-2a is combined with 9-(N-methyl-L-isoleucine)-cyclosporin A.
Aldesleukin The risk or severity of adverse effects can be increased when Aldesleukin is combined with 9-(N-methyl-L-isoleucine)-cyclosporin A.
Adalimumab The risk or severity of adverse effects can be increased when Adalimumab is combined with 9-(N-methyl-L-isoleucine)-cyclosporin A.
Gemtuzumab ozogamicin The risk or severity of adverse effects can be increased when Gemtuzumab ozogamicin is combined with 9-(N-methyl-L-isoleucine)-cyclosporin A.
Pegaspargase The risk or severity of adverse effects can be increased when Pegaspargase is combined with 9-(N-methyl-L-isoleucine)-cyclosporin A.
Infliximab The risk or severity of adverse effects can be increased when Infliximab is combined with 9-(N-methyl-L-isoleucine)-cyclosporin A.
Interferon beta-1b The risk or severity of adverse effects can be increased when Interferon beta-1b is combined with 9-(N-methyl-L-isoleucine)-cyclosporin A.
Interferon alfacon-1 The risk or severity of adverse effects can be increased when Interferon alfacon-1 is combined with 9-(N-methyl-L-isoleucine)-cyclosporin A.
Rituximab The risk or severity of adverse effects can be increased when Rituximab is combined with 9-(N-methyl-L-isoleucine)-cyclosporin A.
Basiliximab The risk or severity of adverse effects can be increased when Basiliximab is combined with 9-(N-methyl-L-isoleucine)-cyclosporin A.
Muromonab The risk or severity of adverse effects can be increased when Muromonab is combined with 9-(N-methyl-L-isoleucine)-cyclosporin A.
Ibritumomab tiuxetan The risk or severity of adverse effects can be increased when Ibritumomab tiuxetan is combined with 9-(N-methyl-L-isoleucine)-cyclosporin A.
Tositumomab The risk or severity of adverse effects can be increased when Tositumomab is combined with 9-(N-methyl-L-isoleucine)-cyclosporin A.
Alemtuzumab The risk or severity of adverse effects can be increased when Alemtuzumab is combined with 9-(N-methyl-L-isoleucine)-cyclosporin A.
Alefacept The risk or severity of adverse effects can be increased when Alefacept is combined with 9-(N-methyl-L-isoleucine)-cyclosporin A.
Efalizumab The risk or severity of adverse effects can be increased when Efalizumab is combined with 9-(N-methyl-L-isoleucine)-cyclosporin A.
Antithymocyte immunoglobulin (rabbit) The risk or severity of adverse effects can be increased when Antithymocyte immunoglobulin (rabbit) is combined with 9-(N-methyl-L-isoleucine)-cyclosporin A.
Interferon alfa-2b The risk or severity of adverse effects can be increased when Interferon alfa-2b is combined with 9-(N-methyl-L-isoleucine)-cyclosporin A.
Daclizumab The risk or severity of adverse effects can be increased when Daclizumab is combined with 9-(N-methyl-L-isoleucine)-cyclosporin A.
Phenylalanine The risk or severity of adverse effects can be increased when Phenylalanine is combined with 9-(N-methyl-L-isoleucine)-cyclosporin A.
Flunisolide The risk or severity of adverse effects can be increased when Flunisolide is combined with 9-(N-methyl-L-isoleucine)-cyclosporin A.
Bortezomib The risk or severity of adverse effects can be increased when Bortezomib is combined with 9-(N-methyl-L-isoleucine)-cyclosporin A.
Cladribine 9-(N-methyl-L-isoleucine)-cyclosporin A may increase the immunosuppressive activities of Cladribine.
Carmustine The risk or severity of adverse effects can be increased when Carmustine is combined with 9-(N-methyl-L-isoleucine)-cyclosporin A.
Amsacrine The risk or severity of adverse effects can be increased when Amsacrine is combined with 9-(N-methyl-L-isoleucine)-cyclosporin A.
Bleomycin The risk or severity of adverse effects can be increased when Bleomycin is combined with 9-(N-methyl-L-isoleucine)-cyclosporin A.
Chlorambucil The risk or severity of adverse effects can be increased when Chlorambucil is combined with 9-(N-methyl-L-isoleucine)-cyclosporin A.
Raltitrexed The risk or severity of adverse effects can be increased when Raltitrexed is combined with 9-(N-methyl-L-isoleucine)-cyclosporin A.
Mitomycin The risk or severity of adverse effects can be increased when Mitomycin is combined with 9-(N-methyl-L-isoleucine)-cyclosporin A.
Bexarotene The risk or severity of adverse effects can be increased when Bexarotene is combined with 9-(N-methyl-L-isoleucine)-cyclosporin A.
Vindesine The risk or severity of adverse effects can be increased when Vindesine is combined with 9-(N-methyl-L-isoleucine)-cyclosporin A.
Floxuridine The risk or severity of adverse effects can be increased when Floxuridine is combined with 9-(N-methyl-L-isoleucine)-cyclosporin A.
Indomethacin The risk or severity of adverse effects can be increased when Indomethacin is combined with 9-(N-methyl-L-isoleucine)-cyclosporin A.
Tioguanine The risk or severity of adverse effects can be increased when Tioguanine is combined with 9-(N-methyl-L-isoleucine)-cyclosporin A.
Vinorelbine The risk or severity of adverse effects can be increased when Vinorelbine is combined with 9-(N-methyl-L-isoleucine)-cyclosporin A.
Dexrazoxane The risk or severity of adverse effects can be increased when Dexrazoxane is combined with 9-(N-methyl-L-isoleucine)-cyclosporin A.
Beclomethasone dipropionate The risk or severity of adverse effects can be increased when Beclomethasone dipropionate is combined with 9-(N-methyl-L-isoleucine)-cyclosporin A.
Sorafenib The risk or severity of adverse effects can be increased when Sorafenib is combined with 9-(N-methyl-L-isoleucine)-cyclosporin A.
Streptozocin The risk or severity of adverse effects can be increased when Streptozocin is combined with 9-(N-methyl-L-isoleucine)-cyclosporin A.
Trifluridine The risk or severity of adverse effects can be increased when Trifluridine is combined with 9-(N-methyl-L-isoleucine)-cyclosporin A.
Gemcitabine The risk or severity of adverse effects can be increased when Gemcitabine is combined with 9-(N-methyl-L-isoleucine)-cyclosporin A.
Betamethasone The risk or severity of adverse effects can be increased when Betamethasone is combined with 9-(N-methyl-L-isoleucine)-cyclosporin A.
Teniposide The risk or severity of adverse effects can be increased when Teniposide is combined with 9-(N-methyl-L-isoleucine)-cyclosporin A.
Epirubicin The risk or severity of adverse effects can be increased when Epirubicin is combined with 9-(N-methyl-L-isoleucine)-cyclosporin A.
Chloramphenicol The risk or severity of adverse effects can be increased when Chloramphenicol is combined with 9-(N-methyl-L-isoleucine)-cyclosporin A.
Lenalidomide The risk or severity of adverse effects can be increased when Lenalidomide is combined with 9-(N-methyl-L-isoleucine)-cyclosporin A.
Altretamine The risk or severity of adverse effects can be increased when Altretamine is combined with 9-(N-methyl-L-isoleucine)-cyclosporin A.
Zidovudine The risk or severity of adverse effects can be increased when Zidovudine is combined with 9-(N-methyl-L-isoleucine)-cyclosporin A.
Cisplatin The risk or severity of adverse effects can be increased when Cisplatin is combined with 9-(N-methyl-L-isoleucine)-cyclosporin A.
Oxaliplatin The risk or severity of adverse effects can be increased when Oxaliplatin is combined with 9-(N-methyl-L-isoleucine)-cyclosporin A.
Cyclophosphamide The risk or severity of adverse effects can be increased when Cyclophosphamide is combined with 9-(N-methyl-L-isoleucine)-cyclosporin A.
Vincristine The risk or severity of adverse effects can be increased when Vincristine is combined with 9-(N-methyl-L-isoleucine)-cyclosporin A.
Fluorouracil The risk or severity of adverse effects can be increased when Fluorouracil is combined with 9-(N-methyl-L-isoleucine)-cyclosporin A.
Propylthiouracil The risk or severity of adverse effects can be increased when Propylthiouracil is combined with 9-(N-methyl-L-isoleucine)-cyclosporin A.
Pentostatin The risk or severity of adverse effects can be increased when Pentostatin is combined with 9-(N-methyl-L-isoleucine)-cyclosporin A.
Methotrexate The risk or severity of adverse effects can be increased when Methotrexate is combined with 9-(N-methyl-L-isoleucine)-cyclosporin A.
Carbamazepine The risk or severity of adverse effects can be increased when Carbamazepine is combined with 9-(N-methyl-L-isoleucine)-cyclosporin A.
Vinblastine The risk or severity of adverse effects can be increased when Vinblastine is combined with 9-(N-methyl-L-isoleucine)-cyclosporin A.
Fluticasone propionate The risk or severity of adverse effects can be increased when Fluticasone propionate is combined with 9-(N-methyl-L-isoleucine)-cyclosporin A.
Fluocinolone acetonide The risk or severity of adverse effects can be increased when Fluocinolone acetonide is combined with 9-(N-methyl-L-isoleucine)-cyclosporin A.
Linezolid The risk or severity of adverse effects can be increased when Linezolid is combined with 9-(N-methyl-L-isoleucine)-cyclosporin A.
Imatinib The risk or severity of adverse effects can be increased when Imatinib is combined with 9-(N-methyl-L-isoleucine)-cyclosporin A.
Triamcinolone The risk or severity of adverse effects can be increased when Triamcinolone is combined with 9-(N-methyl-L-isoleucine)-cyclosporin A.
Clofarabine The risk or severity of adverse effects can be increased when Clofarabine is combined with 9-(N-methyl-L-isoleucine)-cyclosporin A.
Prednisone The risk or severity of adverse effects can be increased when Prednisone is combined with 9-(N-methyl-L-isoleucine)-cyclosporin A.
Pemetrexed The risk or severity of adverse effects can be increased when Pemetrexed is combined with 9-(N-methyl-L-isoleucine)-cyclosporin A.
Fludrocortisone The risk or severity of adverse effects can be increased when Fludrocortisone is combined with 9-(N-methyl-L-isoleucine)-cyclosporin A.
Mycophenolate mofetil The risk or severity of adverse effects can be increased when Mycophenolate mofetil is combined with 9-(N-methyl-L-isoleucine)-cyclosporin A.
Daunorubicin The risk or severity of adverse effects can be increased when Daunorubicin is combined with 9-(N-methyl-L-isoleucine)-cyclosporin A.
Irinotecan The risk or severity of adverse effects can be increased when Irinotecan is combined with 9-(N-methyl-L-isoleucine)-cyclosporin A.
Methimazole The risk or severity of adverse effects can be increased when Methimazole is combined with 9-(N-methyl-L-isoleucine)-cyclosporin A.
Etoposide The risk or severity of adverse effects can be increased when Etoposide is combined with 9-(N-methyl-L-isoleucine)-cyclosporin A.
Sulfasalazine The risk or severity of adverse effects can be increased when Sulfasalazine is combined with 9-(N-methyl-L-isoleucine)-cyclosporin A.
Dacarbazine The risk or severity of adverse effects can be increased when Dacarbazine is combined with 9-(N-methyl-L-isoleucine)-cyclosporin A.
Temozolomide The risk or severity of adverse effects can be increased when Temozolomide is combined with 9-(N-methyl-L-isoleucine)-cyclosporin A.
Penicillamine The risk or severity of adverse effects can be increased when Penicillamine is combined with 9-(N-methyl-L-isoleucine)-cyclosporin A.
Prednisolone The risk or severity of adverse effects can be increased when Prednisolone is combined with 9-(N-methyl-L-isoleucine)-cyclosporin A.
Sirolimus The risk or severity of adverse effects can be increased when Sirolimus is combined with 9-(N-methyl-L-isoleucine)-cyclosporin A.
Mechlorethamine The risk or severity of adverse effects can be increased when Mechlorethamine is combined with 9-(N-methyl-L-isoleucine)-cyclosporin A.
Azacitidine The risk or severity of adverse effects can be increased when Azacitidine is combined with 9-(N-methyl-L-isoleucine)-cyclosporin A.
Carboplatin The risk or severity of adverse effects can be increased when Carboplatin is combined with 9-(N-methyl-L-isoleucine)-cyclosporin A.
Methylprednisolone The risk or severity of adverse effects can be increased when Methylprednisolone is combined with 9-(N-methyl-L-isoleucine)-cyclosporin A.
Dactinomycin The risk or severity of adverse effects can be increased when Dactinomycin is combined with 9-(N-methyl-L-isoleucine)-cyclosporin A.
Cytarabine The risk or severity of adverse effects can be increased when Cytarabine is combined with 9-(N-methyl-L-isoleucine)-cyclosporin A.
Azathioprine The risk or severity of adverse effects can be increased when Azathioprine is combined with 9-(N-methyl-L-isoleucine)-cyclosporin A.
Doxorubicin The risk or severity of adverse effects can be increased when Doxorubicin is combined with 9-(N-methyl-L-isoleucine)-cyclosporin A.
Hydroxyurea The risk or severity of adverse effects can be increased when Hydroxyurea is combined with 9-(N-methyl-L-isoleucine)-cyclosporin A.
Busulfan The risk or severity of adverse effects can be increased when Busulfan is combined with 9-(N-methyl-L-isoleucine)-cyclosporin A.
Mycophenolic acid The risk or severity of adverse effects can be increased when Mycophenolic acid is combined with 9-(N-methyl-L-isoleucine)-cyclosporin A.
Topotecan The risk or severity of adverse effects can be increased when Topotecan is combined with 9-(N-methyl-L-isoleucine)-cyclosporin A.
Mercaptopurine The risk or severity of adverse effects can be increased when Mercaptopurine is combined with 9-(N-methyl-L-isoleucine)-cyclosporin A.
Thalidomide The risk or severity of adverse effects can be increased when Thalidomide is combined with 9-(N-methyl-L-isoleucine)-cyclosporin A.

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