Gossypol

DB13044

small molecule investigational

Deskripsi

Gossypol has been used in trials studying the treatment of Non-small Cell Lung Cancer.

Struktur Molekul 2D

Berat 518.5544
Wujud -

Peta Jejaring Molekuler
Legenda: ObatTargetGenEnzim(Panah → menunjukkan arah efek / relasi)TransporterCarrier

Profil Farmakokinetik

Waktu Paruh (Half-Life) -
Volume Distribusi -
Klirens (Clearance) -

Absorpsi

Data absorpsi tidak tersedia.

Metabolisme

Data metabolisme tidak tersedia.

Rute Eliminasi

Data eliminasi belum tersedia.

Interaksi Obat

402 Data
Aprepitant The serum concentration of Gossypol can be decreased when it is combined with Aprepitant.
Exenatide Exenatide can cause a decrease in the absorption of Gossypol resulting in a reduced serum concentration and potentially a decrease in efficacy.
Thalidomide Gossypol may increase the thrombogenic activities of Thalidomide.
Tranexamic acid Gossypol may increase the thrombogenic activities of Tranexamic acid.
Clobazam The serum concentration of Gossypol can be decreased when it is combined with Clobazam.
Griseofulvin The metabolism of Gossypol can be increased when combined with Griseofulvin.
Fluticasone propionate The serum concentration of Fluticasone propionate can be increased when it is combined with Gossypol.
Trilostane The serum concentration of Trilostane can be increased when it is combined with Gossypol.
Aldosterone The serum concentration of Aldosterone can be increased when it is combined with Gossypol.
Tixocortol The serum concentration of Tixocortol can be increased when it is combined with Gossypol.
Fluprednisolone The serum concentration of Fluprednisolone can be increased when it is combined with Gossypol.
Melengestrol The serum concentration of Melengestrol can be increased when it is combined with Gossypol.
Fluocortin The serum concentration of Fluocortin can be increased when it is combined with Gossypol.
Fluperolone The serum concentration of Fluperolone can be increased when it is combined with Gossypol.
Fluclorolone The serum concentration of Fluclorolone can be increased when it is combined with Gossypol.
Hydrocortisone cypionate The serum concentration of Hydrocortisone cypionate can be increased when it is combined with Gossypol.
Dexamethasone The serum concentration of Dexamethasone can be increased when it is combined with Gossypol.
Flunisolide The serum concentration of Flunisolide can be increased when it is combined with Gossypol.
Beclomethasone dipropionate The serum concentration of Beclomethasone dipropionate can be increased when it is combined with Gossypol.
Betamethasone The serum concentration of Betamethasone can be increased when it is combined with Gossypol.
Fluocinolone acetonide The serum concentration of Fluocinolone acetonide can be increased when it is combined with Gossypol.
Triamcinolone The serum concentration of Triamcinolone can be increased when it is combined with Gossypol.
Prednisone The serum concentration of Prednisone can be increased when it is combined with Gossypol.
Hydrocortisone The serum concentration of Hydrocortisone can be increased when it is combined with Gossypol.
Prednisolone The serum concentration of Prednisolone can be increased when it is combined with Gossypol.
Methylprednisolone The serum concentration of Methylprednisolone can be increased when it is combined with Gossypol.
Budesonide The serum concentration of Budesonide can be increased when it is combined with Gossypol.
Corticotropin The serum concentration of Corticotropin can be increased when it is combined with Gossypol.
Cortisone acetate The serum concentration of Cortisone acetate can be increased when it is combined with Gossypol.
Paramethasone The serum concentration of Paramethasone can be increased when it is combined with Gossypol.
Fluticasone furoate The serum concentration of Fluticasone furoate can be increased when it is combined with Gossypol.
Fluprednidene The serum concentration of Fluprednidene can be increased when it is combined with Gossypol.
Meprednisone The serum concentration of Meprednisone can be increased when it is combined with Gossypol.
Dexamethasone isonicotinate The serum concentration of Dexamethasone isonicotinate can be increased when it is combined with Gossypol.
Deflazacort The serum concentration of Deflazacort can be increased when it is combined with Gossypol.
Cortivazol The serum concentration of Cortivazol can be increased when it is combined with Gossypol.
Prednylidene The serum concentration of Prednylidene can be increased when it is combined with Gossypol.
Cloprednol The serum concentration of Cloprednol can be increased when it is combined with Gossypol.
Fluticasone The serum concentration of Fluticasone can be increased when it is combined with Gossypol.
Mometasone furoate The serum concentration of Mometasone furoate can be increased when it is combined with Gossypol.
Hydrocortisone acetate The serum concentration of Hydrocortisone acetate can be increased when it is combined with Gossypol.
Hydrocortisone succinate The serum concentration of Hydrocortisone succinate can be increased when it is combined with Gossypol.
Prednisolone phosphate The serum concentration of Prednisolone phosphate can be increased when it is combined with Gossypol.
Prednisolone hemisuccinate The serum concentration of Prednisolone hemisuccinate can be increased when it is combined with Gossypol.
Methylprednisolone hemisuccinate The serum concentration of Methylprednisolone hemisuccinate can be increased when it is combined with Gossypol.
Prednisone acetate The serum concentration of Prednisone acetate can be increased when it is combined with Gossypol.
Clocortolone acetate The serum concentration of Clocortolone acetate can be increased when it is combined with Gossypol.
Melengestrol acetate The serum concentration of Melengestrol acetate can be increased when it is combined with Gossypol.
Betamethasone phosphate The serum concentration of Betamethasone phosphate can be increased when it is combined with Gossypol.
Cortisone The serum concentration of Cortisone can be increased when it is combined with Gossypol.
Fludrocortisone The serum concentration of Fludrocortisone can be increased when it is combined with Gossypol.
Ciclesonide The serum concentration of Ciclesonide can be increased when it is combined with Gossypol.
Clobetasol propionate The serum concentration of Clobetasol propionate can be increased when it is combined with Gossypol.
Fluocinonide The serum concentration of Fluocinonide can be increased when it is combined with Gossypol.
Hydrocortisone butyrate The serum concentration of Hydrocortisone butyrate can be increased when it is combined with Gossypol.
Desoximetasone The serum concentration of Desoximetasone can be increased when it is combined with Gossypol.
Mometasone The serum concentration of Mometasone can be increased when it is combined with Gossypol.
Fluocortolone The serum concentration of Fluocortolone can be increased when it is combined with Gossypol.
Prednisolone acetate The serum concentration of Prednisolone acetate can be increased when it is combined with Gossypol.
Fluorometholone The serum concentration of Fluorometholone can be increased when it is combined with Gossypol.
Difluocortolone The serum concentration of Difluocortolone can be increased when it is combined with Gossypol.
Flumethasone The serum concentration of Flumethasone can be increased when it is combined with Gossypol.
Methylprednisolone aceponate The serum concentration of Methylprednisolone aceponate can be increased when it is combined with Gossypol.
Bosentan The serum concentration of Gossypol can be decreased when it is combined with Bosentan.
Carbamazepine The serum concentration of Gossypol can be decreased when it is combined with Carbamazepine.
Piperacillin The therapeutic efficacy of Gossypol can be decreased when used in combination with Piperacillin.
Ampicillin The therapeutic efficacy of Gossypol can be decreased when used in combination with Ampicillin.
Phenoxymethylpenicillin The therapeutic efficacy of Gossypol can be decreased when used in combination with Phenoxymethylpenicillin.
Carbenicillin The therapeutic efficacy of Gossypol can be decreased when used in combination with Carbenicillin.
Oxacillin The therapeutic efficacy of Gossypol can be decreased when used in combination with Oxacillin.
Hetacillin The therapeutic efficacy of Gossypol can be decreased when used in combination with Hetacillin.
Benzylpenicilloyl polylysine The therapeutic efficacy of Gossypol can be decreased when used in combination with Benzylpenicilloyl polylysine.
Mezlocillin The therapeutic efficacy of Gossypol can be decreased when used in combination with Mezlocillin.
Cyclacillin The therapeutic efficacy of Gossypol can be decreased when used in combination with Cyclacillin.
Benzylpenicillin The therapeutic efficacy of Gossypol can be decreased when used in combination with Benzylpenicillin.
Amoxicillin The therapeutic efficacy of Gossypol can be decreased when used in combination with Amoxicillin.
Azlocillin The therapeutic efficacy of Gossypol can be decreased when used in combination with Azlocillin.
Cloxacillin The therapeutic efficacy of Gossypol can be decreased when used in combination with Cloxacillin.
Amdinocillin The therapeutic efficacy of Gossypol can be decreased when used in combination with Amdinocillin.
Bacampicillin The therapeutic efficacy of Gossypol can be decreased when used in combination with Bacampicillin.
Meticillin The therapeutic efficacy of Gossypol can be decreased when used in combination with Meticillin.
Pivampicillin The therapeutic efficacy of Gossypol can be decreased when used in combination with Pivampicillin.
Pivmecillinam The therapeutic efficacy of Gossypol can be decreased when used in combination with Pivmecillinam.
Ticarcillin The therapeutic efficacy of Gossypol can be decreased when used in combination with Ticarcillin.
Azidocillin The therapeutic efficacy of Gossypol can be decreased when used in combination with Azidocillin.
Carindacillin The therapeutic efficacy of Gossypol can be decreased when used in combination with Carindacillin.
Procaine benzylpenicillin The therapeutic efficacy of Gossypol can be decreased when used in combination with Procaine benzylpenicillin.
Sultamicillin The therapeutic efficacy of Gossypol can be decreased when used in combination with Sultamicillin.
Temocillin The therapeutic efficacy of Gossypol can be decreased when used in combination with Temocillin.
Epicillin The therapeutic efficacy of Gossypol can be decreased when used in combination with Epicillin.
Pheneticillin The therapeutic efficacy of Gossypol can be decreased when used in combination with Pheneticillin.
Carfecillin The therapeutic efficacy of Gossypol can be decreased when used in combination with Carfecillin.
Propicillin The therapeutic efficacy of Gossypol can be decreased when used in combination with Propicillin.
Clometocillin The therapeutic efficacy of Gossypol can be decreased when used in combination with Clometocillin.
Sulbenicillin The therapeutic efficacy of Gossypol can be decreased when used in combination with Sulbenicillin.
Penamecillin The therapeutic efficacy of Gossypol can be decreased when used in combination with Penamecillin.
Talampicillin The therapeutic efficacy of Gossypol can be decreased when used in combination with Talampicillin.
Aspoxicillin The therapeutic efficacy of Gossypol can be decreased when used in combination with Aspoxicillin.
Metampicillin The therapeutic efficacy of Gossypol can be decreased when used in combination with Metampicillin.
Lepirudin The therapeutic efficacy of Lepirudin can be decreased when used in combination with Gossypol.

Target Protein

Apoptosis regulator Bcl-2 BCL2
Bcl-2-like protein 1 BCL2L1

Referensi & Sumber

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Sekuens Gen/Protein (FASTA)

Sekuens dimuat saat dibutuhkan agar halaman tetap ringan.
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