Eltoprazine

DB12883

small molecule investigational

Deskripsi

Eltoprazine has been used in trials studying the treatment of Schizophrenia and Cognitive Impairment.

Struktur Molekul 2D

Berat 220.272
Wujud -

Peta Jejaring Molekuler
Legenda: ObatTargetGenEnzim(Panah → menunjukkan arah efek / relasi)TransporterCarrier

Profil Farmakokinetik

Waktu Paruh (Half-Life) -
Volume Distribusi -
Klirens (Clearance) -

Absorpsi

Data absorpsi tidak tersedia.

Metabolisme

Data metabolisme tidak tersedia.

Rute Eliminasi

Data eliminasi belum tersedia.

Interaksi Obat

703 Data
Buprenorphine Eltoprazine may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Doxylamine Doxylamine may increase the central nervous system depressant (CNS depressant) activities of Eltoprazine.
Dronabinol Dronabinol may increase the central nervous system depressant (CNS depressant) activities of Eltoprazine.
Droperidol Droperidol may increase the central nervous system depressant (CNS depressant) activities of Eltoprazine.
Hydrocodone Eltoprazine may increase the central nervous system depressant (CNS depressant) activities of Hydrocodone.
Hydroxyzine Hydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Eltoprazine.
Magnesium sulfate The therapeutic efficacy of Eltoprazine can be increased when used in combination with Magnesium sulfate.
Methotrimeprazine Eltoprazine may increase the central nervous system depressant (CNS depressant) activities of Methotrimeprazine.
Metyrosine Eltoprazine may increase the sedative activities of Metyrosine.
Minocycline Minocycline may increase the central nervous system depressant (CNS depressant) activities of Eltoprazine.
Nabilone Nabilone may increase the central nervous system depressant (CNS depressant) activities of Eltoprazine.
Orphenadrine Eltoprazine may increase the central nervous system depressant (CNS depressant) activities of Orphenadrine.
Paraldehyde Eltoprazine may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
Perampanel Perampanel may increase the central nervous system depressant (CNS depressant) activities of Eltoprazine.
Pramipexole Eltoprazine may increase the sedative activities of Pramipexole.
Ropinirole Eltoprazine may increase the sedative activities of Ropinirole.
Rotigotine Eltoprazine may increase the sedative activities of Rotigotine.
Rufinamide The risk or severity of adverse effects can be increased when Rufinamide is combined with Eltoprazine.
Sodium oxybate Eltoprazine may increase the central nervous system depressant (CNS depressant) activities of Sodium oxybate.
Suvorexant Eltoprazine may increase the central nervous system depressant (CNS depressant) activities of Suvorexant.
Tapentadol Tapentadol may increase the central nervous system depressant (CNS depressant) activities of Eltoprazine.
Thalidomide Eltoprazine may increase the central nervous system depressant (CNS depressant) activities of Thalidomide.
Zolpidem Eltoprazine may increase the central nervous system depressant (CNS depressant) activities of Zolpidem.
Methadone The risk or severity of adverse effects can be increased when Methadone is combined with Eltoprazine.
Linezolid The risk or severity of serotonin syndrome can be increased when Linezolid is combined with Eltoprazine.
Dicoumarol The risk or severity of adverse effects can be increased when Eltoprazine is combined with Dicoumarol.
Phenindione The risk or severity of adverse effects can be increased when Eltoprazine is combined with Phenindione.
Warfarin The risk or severity of adverse effects can be increased when Eltoprazine is combined with Warfarin.
Phenprocoumon The risk or severity of adverse effects can be increased when Eltoprazine is combined with Phenprocoumon.
Acenocoumarol The risk or severity of adverse effects can be increased when Eltoprazine is combined with Acenocoumarol.
4-hydroxycoumarin The risk or severity of adverse effects can be increased when Eltoprazine is combined with 4-hydroxycoumarin.
Coumarin The risk or severity of adverse effects can be increased when Eltoprazine is combined with Coumarin.
(R)-warfarin The risk or severity of adverse effects can be increased when Eltoprazine is combined with (R)-warfarin.
Ethyl biscoumacetate The risk or severity of adverse effects can be increased when Eltoprazine is combined with Ethyl biscoumacetate.
Fluindione The risk or severity of adverse effects can be increased when Eltoprazine is combined with Fluindione.
Clorindione The risk or severity of adverse effects can be increased when Eltoprazine is combined with Clorindione.
Diphenadione The risk or severity of adverse effects can be increased when Eltoprazine is combined with Diphenadione.
Tioclomarol The risk or severity of adverse effects can be increased when Eltoprazine is combined with Tioclomarol.
(S)-Warfarin The risk or severity of adverse effects can be increased when Eltoprazine is combined with (S)-Warfarin.
Mirtazapine Eltoprazine may increase the serotonergic activities of Mirtazapine.
Ethanol Eltoprazine may increase the central nervous system depressant (CNS depressant) activities of Ethanol.
Azelastine Eltoprazine may increase the central nervous system depressant (CNS depressant) activities of Azelastine.
Brimonidine Brimonidine may increase the central nervous system depressant (CNS depressant) activities of Eltoprazine.
Fluvoxamine The risk or severity of adverse effects can be increased when Eltoprazine is combined with Fluvoxamine.
Citalopram The risk or severity of adverse effects can be increased when Eltoprazine is combined with Citalopram.
Duloxetine The risk or severity of adverse effects can be increased when Eltoprazine is combined with Duloxetine.
Paroxetine The risk or severity of adverse effects can be increased when Eltoprazine is combined with Paroxetine.
Sertraline The risk or severity of adverse effects can be increased when Eltoprazine is combined with Sertraline.
Sibutramine The risk or severity of adverse effects can be increased when Eltoprazine is combined with Sibutramine.
Nefazodone The risk or severity of adverse effects can be increased when Eltoprazine is combined with Nefazodone.
Zimelidine The risk or severity of adverse effects can be increased when Eltoprazine is combined with Zimelidine.
Dapoxetine The risk or severity of adverse effects can be increased when Eltoprazine is combined with Dapoxetine.
Milnacipran The risk or severity of adverse effects can be increased when Eltoprazine is combined with Milnacipran.
Desvenlafaxine The risk or severity of serotonin syndrome can be increased when Desvenlafaxine is combined with Eltoprazine.
Seproxetine The risk or severity of adverse effects can be increased when Eltoprazine is combined with Seproxetine.
Levomilnacipran The risk or severity of serotonin syndrome can be increased when Eltoprazine is combined with Levomilnacipran.
Indalpine The risk or severity of adverse effects can be increased when Eltoprazine is combined with Indalpine.
Ritanserin The risk or severity of adverse effects can be increased when Eltoprazine is combined with Ritanserin.
Alaproclate The risk or severity of adverse effects can be increased when Eltoprazine is combined with Alaproclate.
Methylene blue Eltoprazine may increase the serotonergic activities of Methylene blue.
Zopiclone The risk or severity of adverse effects can be increased when Eltoprazine is combined with Zopiclone.
Botulinum toxin type B The risk or severity of CNS depression can be increased when Botulinum toxin type B is combined with Eltoprazine.
Botulinum toxin type A The risk or severity of CNS depression can be increased when Botulinum toxin type A is combined with Eltoprazine.
Tryptophan The risk or severity of CNS depression can be increased when Tryptophan is combined with Eltoprazine.
Baclofen Baclofen may increase the central nervous system depressant (CNS depressant) activities of Eltoprazine.
Lorazepam The risk or severity of CNS depression can be increased when Lorazepam is combined with Eltoprazine.
Ethchlorvynol The risk or severity of CNS depression can be increased when Ethchlorvynol is combined with Eltoprazine.
Succinylcholine The risk or severity of CNS depression can be increased when Succinylcholine is combined with Eltoprazine.
Reserpine The risk or severity of CNS depression can be increased when Reserpine is combined with Eltoprazine.
Eletriptan The risk or severity of CNS depression can be increased when Eletriptan is combined with Eltoprazine.
Enflurane The risk or severity of CNS depression can be increased when Enflurane is combined with Eltoprazine.
Temazepam The risk or severity of CNS depression can be increased when Temazepam is combined with Eltoprazine.
Reboxetine The risk or severity of CNS depression can be increased when Reboxetine is combined with Eltoprazine.
Butabarbital The risk or severity of CNS depression can be increased when Butabarbital is combined with Eltoprazine.
Butalbital The risk or severity of CNS depression can be increased when Butalbital is combined with Eltoprazine.
Methysergide The risk or severity of CNS depression can be increased when Methysergide is combined with Eltoprazine.
Cabergoline The risk or severity of CNS depression can be increased when Cabergoline is combined with Eltoprazine.
Phenytoin The risk or severity of CNS depression can be increased when Phenytoin is combined with Eltoprazine.
Topiramate The risk or severity of CNS depression can be increased when Topiramate is combined with Eltoprazine.
Clemastine The risk or severity of CNS depression can be increased when Clemastine is combined with Eltoprazine.
Venlafaxine The risk or severity of serotonin syndrome can be increased when Eltoprazine is combined with Venlafaxine.
Etomidate The risk or severity of CNS depression can be increased when Etomidate is combined with Eltoprazine.
Morphine The risk or severity of CNS depression can be increased when Morphine is combined with Eltoprazine.
Talbutal The risk or severity of CNS depression can be increased when Talbutal is combined with Eltoprazine.
Pentobarbital The risk or severity of CNS depression can be increased when Pentobarbital is combined with Eltoprazine.
Valproic acid The risk or severity of CNS depression can be increased when Valproic acid is combined with Eltoprazine.
Zolmitriptan The risk or severity of CNS depression can be increased when Zolmitriptan is combined with Eltoprazine.
Codeine The risk or severity of CNS depression can be increased when Codeine is combined with Eltoprazine.
Dihydroergotamine The risk or severity of CNS depression can be increased when Dihydroergotamine is combined with Eltoprazine.
Amitriptyline The risk or severity of CNS depression can be increased when Amitriptyline is combined with Eltoprazine.
Tolcapone The risk or severity of CNS depression can be increased when Tolcapone is combined with Eltoprazine.
Hydromorphone The risk or severity of CNS depression can be increased when Hydromorphone is combined with Eltoprazine.
Olanzapine The risk or severity of CNS depression can be increased when Olanzapine is combined with Eltoprazine.
Cetirizine The risk or severity of CNS depression can be increased when Cetirizine is combined with Eltoprazine.
Protriptyline The risk or severity of CNS depression can be increased when Protriptyline is combined with Eltoprazine.
Trimethadione The risk or severity of CNS depression can be increased when Trimethadione is combined with Eltoprazine.
Clobazam The risk or severity of sedation, somnolence, and CNS depression can be increased when Clobazam is combined with Eltoprazine.
Chlorzoxazone The risk or severity of CNS depression can be increased when Chlorzoxazone is combined with Eltoprazine.
Clozapine The risk or severity of CNS depression can be increased when Clozapine is combined with Eltoprazine.
Meprobamate The risk or severity of CNS depression can be increased when Meprobamate is combined with Eltoprazine.

Target Protein

5-hydroxytryptamine receptor 1A HTR1A
5-hydroxytryptamine receptor 2C HTR2C
5-hydroxytryptamine receptor 1B HTR1B

Referensi & Sumber

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Sekuens Gen/Protein (FASTA)

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