Pradigastat

DB12866

small molecule investigational

Deskripsi

Pradigastat has been used in trials studying the treatment of Non-alcoholic Fatty Liver Disease (NAFLD).

Struktur Molekul 2D

Berat 455.481
Wujud -

Peta Jejaring Molekuler
Legenda: ObatTargetGenEnzim(Panah → menunjukkan arah efek / relasi)TransporterCarrier

Profil Farmakokinetik

Waktu Paruh (Half-Life) -
Volume Distribusi -
Klirens (Clearance) -

Absorpsi

Data absorpsi tidak tersedia.

Metabolisme

Data metabolisme tidak tersedia.

Rute Eliminasi

Data eliminasi belum tersedia.

Interaksi Obat

70 Data
Succinic acid The excretion of Succinic acid can be decreased when combined with Pradigastat.
Citrulline The excretion of Citrulline can be decreased when combined with Pradigastat.
Pravastatin The excretion of Pravastatin can be decreased when combined with Pradigastat.
Oseltamivir The excretion of Oseltamivir can be decreased when combined with Pradigastat.
Cefotiam The excretion of Cefotiam can be decreased when combined with Pradigastat.
Conjugated estrogens The excretion of Conjugated estrogens can be decreased when combined with Pradigastat.
Tenofovir disoproxil The excretion of Tenofovir disoproxil can be decreased when combined with Pradigastat.
Piperacillin The excretion of Piperacillin can be decreased when combined with Pradigastat.
Indomethacin The excretion of Indomethacin can be decreased when combined with Pradigastat.
Aminohippuric acid The excretion of Aminohippuric acid can be decreased when combined with Pradigastat.
Trifluridine The excretion of Trifluridine can be decreased when combined with Pradigastat.
Allopurinol The excretion of Allopurinol can be decreased when combined with Pradigastat.
Zidovudine The excretion of Zidovudine can be decreased when combined with Pradigastat.
Cimetidine The excretion of Cimetidine can be decreased when combined with Pradigastat.
Cefdinir The excretion of Cefdinir can be decreased when combined with Pradigastat.
Methotrexate The excretion of Methotrexate can be decreased when combined with Pradigastat.
Cephalexin The excretion of Cephalexin can be decreased when combined with Pradigastat.
Valaciclovir The excretion of Valaciclovir can be decreased when combined with Pradigastat.
Levocarnitine The excretion of Levocarnitine can be decreased when combined with Pradigastat.
Leucovorin The excretion of Leucovorin can be decreased when combined with Pradigastat.
Fluorescein The excretion of Fluorescein can be decreased when combined with Pradigastat.
Hydrocortisone The excretion of Hydrocortisone can be decreased when combined with Pradigastat.
Tetracycline The excretion of Tetracycline can be decreased when combined with Pradigastat.
Estradiol The excretion of Estradiol can be decreased when combined with Pradigastat.
Acyclovir The excretion of Acyclovir can be decreased when combined with Pradigastat.
Cefaclor The excretion of Cefaclor can be decreased when combined with Pradigastat.
Ranitidine The excretion of Ranitidine can be decreased when combined with Pradigastat.
Quinapril The excretion of Quinapril can be decreased when combined with Pradigastat.
Bumetanide The excretion of Bumetanide can be decreased when combined with Pradigastat.
Dinoprostone The excretion of Dinoprostone can be decreased when combined with Pradigastat.
Famotidine The excretion of Famotidine can be decreased when combined with Pradigastat.
Fexofenadine The excretion of Fexofenadine can be decreased when combined with Pradigastat.
Benzylpenicillin The excretion of Benzylpenicillin can be decreased when combined with Pradigastat.
Rosuvastatin The excretion of Rosuvastatin can be decreased when combined with Pradigastat.
Captopril The excretion of Captopril can be decreased when combined with Pradigastat.
Sitagliptin The excretion of Sitagliptin can be decreased when combined with Pradigastat.
Cefazolin The excretion of Cefazolin can be decreased when combined with Pradigastat.
Ceftizoxime The excretion of Ceftizoxime can be decreased when combined with Pradigastat.
Cefacetrile The excretion of Cefacetrile can be decreased when combined with Pradigastat.
Ceftibuten The excretion of Ceftibuten can be decreased when combined with Pradigastat.
Tazobactam The excretion of Tazobactam can be decreased when combined with Pradigastat.
Cyclic adenosine monophosphate The excretion of Cyclic adenosine monophosphate can be decreased when combined with Pradigastat.
Cholic Acid The excretion of Cholic Acid can be decreased when combined with Pradigastat.
Glutaric Acid The excretion of Glutaric Acid can be decreased when combined with Pradigastat.
Oxalic Acid The excretion of Oxalic Acid can be decreased when combined with Pradigastat.
Taurocholic acid The excretion of Taurocholic acid can be decreased when combined with Pradigastat.
Doripenem The excretion of Doripenem can be decreased when combined with Pradigastat.
Saxagliptin The excretion of Saxagliptin can be decreased when combined with Pradigastat.
Ellagic acid The excretion of Ellagic acid can be decreased when combined with Pradigastat.
Cefaloridine The excretion of Cefaloridine can be decreased when combined with Pradigastat.
Avibactam The excretion of Avibactam can be decreased when combined with Pradigastat.
Eluxadoline The excretion of Eluxadoline can be decreased when combined with Pradigastat.
Silibinin The excretion of Silibinin can be decreased when combined with Pradigastat.
Tenofovir alafenamide The excretion of Tenofovir alafenamide can be decreased when combined with Pradigastat.
Baricitinib The serum concentration of Baricitinib can be increased when it is combined with Pradigastat.
Relebactam The excretion of Relebactam can be decreased when combined with Pradigastat.
Tenofovir The excretion of Tenofovir can be decreased when combined with Pradigastat.
Hydrochlorothiazide The excretion of Hydrochlorothiazide can be decreased when combined with Pradigastat.
Dexamethasone The excretion of Dexamethasone can be decreased when combined with Pradigastat.
Oxytetracycline The excretion of Oxytetracycline can be decreased when combined with Pradigastat.
Polythiazide The excretion of Polythiazide can be decreased when combined with Pradigastat.
Prednisolone phosphate The excretion of Prednisolone phosphate can be decreased when combined with Pradigastat.
Dexamethasone acetate The excretion of Dexamethasone acetate can be decreased when combined with Pradigastat.
Pemetrexed Pradigastat may decrease the excretion rate of Pemetrexed which could result in a higher serum level.
Mercaptopurine The excretion of Mercaptopurine can be decreased when combined with Pradigastat.
Valproic acid The excretion of Valproic acid can be decreased when combined with Pradigastat.
Clofarabine The excretion of Clofarabine can be decreased when combined with Pradigastat.
Vadadustat The serum concentration of Vadadustat can be increased when it is combined with Pradigastat.
Seladelpar The excretion of Seladelpar can be decreased when combined with Pradigastat.
Sulopenem etzadroxil The serum concentration of Sulopenem etzadroxil can be increased when it is combined with Pradigastat.

Target Protein

Diacylglycerol O-acyltransferase 1 DGAT1

Referensi & Sumber

Belum ada data referensi/link/attachment untuk obat ini pada database. Jalankan import DrugBank untuk mengisi field referensi.

Contoh Produk & Brand

Produk: 0 • International brands: 0
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Sekuens Gen/Protein (FASTA)

Sekuens dimuat saat dibutuhkan agar halaman tetap ringan.
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