Lometrexol has been used in trials studying the treatment of Lung Cancer, Drug/Agent Toxicity by Tissue/Organ, and Unspecified Adult Solid Tumor, Protocol Specific.
Fitur visualisasi ini dikembangkan menggunakan pendekatan Graph Theory untuk memetakan hubungan polifarmasi dan molekuler. Entitas (Obat, Target, Gen) direpresentasikan sebagai Simpul (Nodes), sedangkan hubungan biologisnya sebagai Sisi (Edges).
drugbank-id dan name pada skema XML DrugBank.targets/target yang memuat polipeptida sasaran.gene-name dan varian snp-effects.Tata letak grafik menggunakan algoritma Force-Directed Graph (Barnes-Hut). Model fisika ini menerapkan gaya tolak-menolak antar simpul (Gravitasi: -3000) agar tidak tumpang tindih, serta gaya pegas (Spring: 0.04) pada garis penghubung untuk fleksibilitas interaksi.
| Tetrahydrofolic acid | The therapeutic efficacy of Lometrexol can be decreased when used in combination with Tetrahydrofolic acid. |
| Folic acid | The therapeutic efficacy of Lometrexol can be decreased when used in combination with Folic acid. |
| Leucovorin | The therapeutic efficacy of Lometrexol can be decreased when used in combination with Leucovorin. |
| (6S)-5,6,7,8-tetrahydrofolic acid | The therapeutic efficacy of Lometrexol can be decreased when used in combination with (6S)-5,6,7,8-tetrahydrofolic acid. |
| Triglu-5-formyl-tetrahydrofolate | The therapeutic efficacy of Lometrexol can be decreased when used in combination with Triglu-5-formyl-tetrahydrofolate. |
| Levoleucovorin | The therapeutic efficacy of Lometrexol can be decreased when used in combination with Levoleucovorin. |
| 5-methyltetrahydrofolic acid | The therapeutic efficacy of Lometrexol can be decreased when used in combination with 5-methyltetrahydrofolic acid. |
| Glucarpidase | The serum concentration of the active metabolites of Lometrexol can be reduced when Lometrexol is used in combination with Glucarpidase resulting in a loss in efficacy. |
| Acetazolamide | The therapeutic efficacy of Lometrexol can be increased when used in combination with Acetazolamide. |
| Darbepoetin alfa | The risk or severity of Thrombosis can be increased when Darbepoetin alfa is combined with Lometrexol. |
| Erythropoietin | The risk or severity of Thrombosis can be increased when Erythropoietin is combined with Lometrexol. |
| Peginesatide | The risk or severity of Thrombosis can be increased when Peginesatide is combined with Lometrexol. |
| Methoxy polyethylene glycol-epoetin beta | The risk or severity of Thrombosis can be increased when Methoxy polyethylene glycol-epoetin beta is combined with Lometrexol. |
| Lidocaine | The risk or severity of methemoglobinemia can be increased when Lometrexol is combined with Lidocaine. |
| Ropivacaine | The risk or severity of methemoglobinemia can be increased when Lometrexol is combined with Ropivacaine. |
| Bupivacaine | The risk or severity of methemoglobinemia can be increased when Lometrexol is combined with Bupivacaine. |
| Cinchocaine | The risk or severity of methemoglobinemia can be increased when Lometrexol is combined with Cinchocaine. |
| Dyclonine | The risk or severity of methemoglobinemia can be increased when Lometrexol is combined with Dyclonine. |
| Procaine | The risk or severity of methemoglobinemia can be increased when Lometrexol is combined with Procaine. |
| Prilocaine | The risk or severity of methemoglobinemia can be increased when Lometrexol is combined with Prilocaine. |
| Proparacaine | The risk or severity of methemoglobinemia can be increased when Lometrexol is combined with Proparacaine. |
| Meloxicam | The risk or severity of methemoglobinemia can be increased when Lometrexol is combined with Meloxicam. |
| Oxybuprocaine | The risk or severity of methemoglobinemia can be increased when Lometrexol is combined with Oxybuprocaine. |
| Cocaine | The risk or severity of methemoglobinemia can be increased when Lometrexol is combined with Cocaine. |
| Mepivacaine | The risk or severity of methemoglobinemia can be increased when Lometrexol is combined with Mepivacaine. |
| Levobupivacaine | The risk or severity of methemoglobinemia can be increased when Lometrexol is combined with Levobupivacaine. |
| Diphenhydramine | The risk or severity of methemoglobinemia can be increased when Lometrexol is combined with Diphenhydramine. |
| Benzocaine | The risk or severity of methemoglobinemia can be increased when Lometrexol is combined with Benzocaine. |
| Chloroprocaine | The risk or severity of methemoglobinemia can be increased when Lometrexol is combined with Chloroprocaine. |
| Phenol | The risk or severity of methemoglobinemia can be increased when Lometrexol is combined with Phenol. |
| Tetrodotoxin | The risk or severity of methemoglobinemia can be increased when Lometrexol is combined with Tetrodotoxin. |
| Benzyl alcohol | The risk or severity of methemoglobinemia can be increased when Lometrexol is combined with Benzyl alcohol. |
| Capsaicin | The risk or severity of methemoglobinemia can be increased when Lometrexol is combined with Capsaicin. |
| Etidocaine | The risk or severity of methemoglobinemia can be increased when Lometrexol is combined with Etidocaine. |
| Articaine | The risk or severity of methemoglobinemia can be increased when Lometrexol is combined with Articaine. |
| Tetracaine | The risk or severity of methemoglobinemia can be increased when Lometrexol is combined with Tetracaine. |
| Propoxycaine | The risk or severity of methemoglobinemia can be increased when Lometrexol is combined with Propoxycaine. |
| Pramocaine | The risk or severity of methemoglobinemia can be increased when Lometrexol is combined with Pramocaine. |
| Butamben | The risk or severity of methemoglobinemia can be increased when Lometrexol is combined with Butamben. |
| Butacaine | The risk or severity of methemoglobinemia can be increased when Lometrexol is combined with Butacaine. |
| Oxetacaine | The risk or severity of methemoglobinemia can be increased when Lometrexol is combined with Oxetacaine. |
| Ethyl chloride | The risk or severity of methemoglobinemia can be increased when Lometrexol is combined with Ethyl chloride. |
| Butanilicaine | The risk or severity of methemoglobinemia can be increased when Lometrexol is combined with Butanilicaine. |
| Metabutethamine | The risk or severity of methemoglobinemia can be increased when Lometrexol is combined with Metabutethamine. |
| Quinisocaine | The risk or severity of methemoglobinemia can be increased when Lometrexol is combined with Quinisocaine. |
| Nelarabine | The risk or severity of adverse effects can be increased when Nelarabine is combined with Lometrexol. |
| Ambroxol | The risk or severity of methemoglobinemia can be increased when Lometrexol is combined with Ambroxol. |
| Etrasimod | The risk or severity of immunosuppression can be increased when Lometrexol is combined with Etrasimod. |