Bucindolol

DB12752

small molecule investigational

Deskripsi

Bucindolol has been investigated in Heart Failure.

Struktur Molekul 2D

Berat 363.461
Wujud -

Peta Jejaring Molekuler
Legenda: ObatTargetGenEnzim(Panah → menunjukkan arah efek / relasi)TransporterCarrier

Profil Farmakokinetik

Waktu Paruh (Half-Life) -
Volume Distribusi -
Klirens (Clearance) -

Absorpsi

Data absorpsi tidak tersedia.

Metabolisme

Data metabolisme tidak tersedia.

Rute Eliminasi

Data eliminasi belum tersedia.

Interaksi Obat

1121 Data
Ceritinib Bucindolol may increase the bradycardic activities of Ceritinib.
Ivabradine Bucindolol may increase the bradycardic activities of Ivabradine.
Ruxolitinib Ruxolitinib may increase the bradycardic activities of Bucindolol.
Atomoxetine The risk or severity of hypertension can be increased when Atomoxetine is combined with Bucindolol.
Linezolid The risk or severity of hypertension can be increased when Linezolid is combined with Bucindolol.
Amiodarone The therapeutic efficacy of Bucindolol can be increased when used in combination with Amiodarone.
Bupivacaine The serum concentration of Bupivacaine can be increased when it is combined with Bucindolol.
Dipyridamole Dipyridamole may increase the bradycardic activities of Bucindolol.
Disopyramide Disopyramide may increase the bradycardic activities of Bucindolol.
Dronedarone Dronedarone may increase the bradycardic activities of Bucindolol.
Fingolimod Bucindolol may increase the bradycardic activities of Fingolimod.
Floctafenine The risk or severity of adverse effects can be increased when Bucindolol is combined with Floctafenine.
Mepivacaine The serum concentration of Mepivacaine can be increased when it is combined with Bucindolol.
Methacholine Bucindolol may increase the bronchoconstrictory activities of Methacholine.
Midodrine The therapeutic efficacy of Midodrine can be decreased when used in combination with Bucindolol.
Nifedipine The risk or severity of congestive heart failure and hypotension can be increased when Nifedipine is combined with Bucindolol.
Propafenone The risk or severity of adverse effects can be increased when Propafenone is combined with Bucindolol.
Regorafenib Regorafenib may increase the bradycardic activities of Bucindolol.
Reserpine Reserpine may increase the hypotensive activities of Bucindolol.
Deserpidine Deserpidine may increase the hypotensive activities of Bucindolol.
Guanethidine Guanethidine may increase the hypotensive activities of Bucindolol.
Rivastigmine Bucindolol may increase the bradycardic activities of Rivastigmine.
Dapoxetine Dapoxetine may increase the orthostatic hypotensive activities of Bucindolol.
Lurasidone Bucindolol may increase the hypotensive activities of Lurasidone.
Mirabegron The serum concentration of Bucindolol can be increased when it is combined with Mirabegron.
Tedizolid phosphate Tedizolid phosphate may increase the hypertensive activities of Bucindolol.
Insulin argine Bucindolol may increase the hypoglycemic activities of Insulin argine.
Caffeine The risk or severity of adverse effects can be increased when Bucindolol is combined with Caffeine.
Dyphylline The risk or severity of adverse effects can be increased when Bucindolol is combined with Dyphylline.
Pentoxifylline The risk or severity of adverse effects can be increased when Bucindolol is combined with Pentoxifylline.
Mercaptopurine The risk or severity of adverse effects can be increased when Bucindolol is combined with Mercaptopurine.
Aminophylline The risk or severity of adverse effects can be increased when Bucindolol is combined with Aminophylline.
Oxtriphylline The risk or severity of adverse effects can be increased when Bucindolol is combined with Oxtriphylline.
Theobromine The risk or severity of adverse effects can be increased when Bucindolol is combined with Theobromine.
Fenethylline The risk or severity of adverse effects can be increased when Bucindolol is combined with Fenethylline.
8-azaguanine The risk or severity of adverse effects can be increased when Bucindolol is combined with 8-azaguanine.
7,9-Dimethylguanine The risk or severity of adverse effects can be increased when Bucindolol is combined with 7,9-Dimethylguanine.
Xanthine The risk or severity of adverse effects can be increased when Bucindolol is combined with Xanthine.
7-Deazaguanine The risk or severity of adverse effects can be increased when Bucindolol is combined with 7-Deazaguanine.
Guanine The risk or severity of adverse effects can be increased when Bucindolol is combined with Guanine.
9-Methylguanine The risk or severity of adverse effects can be increased when Bucindolol is combined with 9-Methylguanine.
Peldesine The risk or severity of adverse effects can be increased when Bucindolol is combined with Peldesine.
Hypoxanthine The risk or severity of adverse effects can be increased when Bucindolol is combined with Hypoxanthine.
9-Deazaguanine The risk or severity of adverse effects can be increased when Bucindolol is combined with 9-Deazaguanine.
Propentofylline The risk or severity of adverse effects can be increased when Bucindolol is combined with Propentofylline.
Valomaciclovir The risk or severity of adverse effects can be increased when Bucindolol is combined with Valomaciclovir.
3-isobutyl-1-methyl-7H-xanthine The risk or severity of adverse effects can be increased when Bucindolol is combined with 3-isobutyl-1-methyl-7H-xanthine.
Uric acid The risk or severity of adverse effects can be increased when Bucindolol is combined with Uric acid.
6-O-benzylguanine The risk or severity of adverse effects can be increased when Bucindolol is combined with 6-O-benzylguanine.
Lisofylline The risk or severity of adverse effects can be increased when Bucindolol is combined with Lisofylline.
Lobucavir The risk or severity of adverse effects can be increased when Bucindolol is combined with Lobucavir.
Cafedrine The risk or severity of adverse effects can be increased when Bucindolol is combined with Cafedrine.
Bamifylline The risk or severity of adverse effects can be increased when Bucindolol is combined with Bamifylline.
Proxyphylline The risk or severity of adverse effects can be increased when Bucindolol is combined with Proxyphylline.
Acefylline The risk or severity of adverse effects can be increased when Bucindolol is combined with Acefylline.
Etamiphylline The risk or severity of adverse effects can be increased when Bucindolol is combined with Etamiphylline.
Pentifylline The risk or severity of adverse effects can be increased when Bucindolol is combined with Pentifylline.
Bufylline The risk or severity of adverse effects can be increased when Bucindolol is combined with Bufylline.
Bromotheophylline The risk or severity of adverse effects can be increased when Bucindolol is combined with Bromotheophylline.
Furafylline The risk or severity of adverse effects can be increased when Bucindolol is combined with Furafylline.
8-chlorotheophylline The risk or severity of adverse effects can be increased when Bucindolol is combined with 8-chlorotheophylline.
PCS-499 The risk or severity of adverse effects can be increased when Bucindolol is combined with PCS-499.
Iobenguane Bucindolol can cause a decrease in the absorption of Iobenguane resulting in a reduced serum concentration and potentially a decrease in efficacy.
Nicotine The risk or severity of adverse effects can be increased when Bucindolol is combined with Nicotine.
Cevimeline The risk or severity of adverse effects can be increased when Bucindolol is combined with Cevimeline.
Carbamoylcholine The risk or severity of adverse effects can be increased when Bucindolol is combined with Carbamoylcholine.
Bethanechol The risk or severity of adverse effects can be increased when Bucindolol is combined with Bethanechol.
Pilocarpine The risk or severity of adverse effects can be increased when Bucindolol is combined with Pilocarpine.
Varenicline The risk or severity of adverse effects can be increased when Bucindolol is combined with Varenicline.
Acetylcholine The risk or severity of adverse effects can be increased when Bucindolol is combined with Acetylcholine.
Arecoline The risk or severity of adverse effects can be increased when Bucindolol is combined with Arecoline.
Lobeline The risk or severity of adverse effects can be increased when Bucindolol is combined with Lobeline.
NGX267 The risk or severity of adverse effects can be increased when Bucindolol is combined with NGX267.
GTS-21 The risk or severity of adverse effects can be increased when Bucindolol is combined with GTS-21.
Epibatidine The risk or severity of adverse effects can be increased when Bucindolol is combined with Epibatidine.
Xanomeline The risk or severity of adverse effects can be increased when Bucindolol is combined with Xanomeline.
Thiethylperazine The serum concentration of Bucindolol can be increased when it is combined with Thiethylperazine.
Prochlorperazine The serum concentration of Bucindolol can be increased when it is combined with Prochlorperazine.
Triflupromazine The serum concentration of Bucindolol can be increased when it is combined with Triflupromazine.
Fluphenazine The serum concentration of Bucindolol can be increased when it is combined with Fluphenazine.
Moricizine The serum concentration of Bucindolol can be increased when it is combined with Moricizine.
Perphenazine The serum concentration of Bucindolol can be increased when it is combined with Perphenazine.
Mesoridazine The serum concentration of Bucindolol can be increased when it is combined with Mesoridazine.
Acetophenazine The serum concentration of Bucindolol can be increased when it is combined with Acetophenazine.
Promethazine The serum concentration of Bucindolol can be increased when it is combined with Promethazine.
Alimemazine The serum concentration of Bucindolol can be increased when it is combined with Alimemazine.
Aceprometazine The serum concentration of Bucindolol can be increased when it is combined with Aceprometazine.
Pipotiazine The serum concentration of Bucindolol can be increased when it is combined with Pipotiazine.
BL-1020 The serum concentration of Bucindolol can be increased when it is combined with BL-1020.
Cyamemazine The serum concentration of Bucindolol can be increased when it is combined with Cyamemazine.
Methylene blue The serum concentration of Bucindolol can be increased when it is combined with Methylene blue.
Propiopromazine The serum concentration of Bucindolol can be increased when it is combined with Propiopromazine.
Perazine The serum concentration of Bucindolol can be increased when it is combined with Perazine.
Butaperazine The serum concentration of Bucindolol can be increased when it is combined with Butaperazine.
Chlorproethazine The serum concentration of Bucindolol can be increased when it is combined with Chlorproethazine.
Thiazinam The serum concentration of Bucindolol can be increased when it is combined with Thiazinam.
Dixyrazine The serum concentration of Bucindolol can be increased when it is combined with Dixyrazine.
Perphenazine enanthate The serum concentration of Bucindolol can be increased when it is combined with Perphenazine enanthate.
Digoxin Bucindolol may increase the bradycardic activities of Digoxin.
Acetyldigitoxin Bucindolol may increase the bradycardic activities of Acetyldigitoxin.

Target Protein

Beta-2 adrenergic receptor ADRB2
Beta-1 adrenergic receptor ADRB1

Referensi & Sumber

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Sekuens Gen/Protein (FASTA)

Sekuens dimuat saat dibutuhkan agar halaman tetap ringan.
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