Piperine

DB12582

small molecule investigational

Deskripsi

Bioperine has been used in trials studying the treatment of Multiple Myeloma and Deglutition Disorders.

Struktur Molekul 2D

Berat 285.3377
Wujud -

Peta Jejaring Molekuler
Legenda: ObatTargetGenEnzim(Panah → menunjukkan arah efek / relasi)TransporterCarrier

Profil Farmakokinetik

Waktu Paruh (Half-Life) -
Volume Distribusi -
Klirens (Clearance) -

Absorpsi

Data absorpsi tidak tersedia.

Metabolisme

Data metabolisme tidak tersedia.

Rute Eliminasi

Data eliminasi belum tersedia.

Interaksi Obat

294 Data
Ubidecarenone The serum concentration of Ubidecarenone can be increased when it is combined with Piperine.
Lefamulin Piperine may decrease the excretion rate of Lefamulin which could result in a higher serum level.
Voxelotor The serum concentration of Voxelotor can be increased when it is combined with Piperine.
Levamlodipine The serum concentration of Levamlodipine can be increased when it is combined with Piperine.
Ubrogepant The serum concentration of Ubrogepant can be increased when it is combined with Piperine.
Rimegepant The serum concentration of Rimegepant can be increased when it is combined with Piperine.
Haloperidol The serum concentration of Haloperidol can be increased when it is combined with Piperine.
Pralsetinib The serum concentration of Pralsetinib can be increased when it is combined with Piperine.
Relugolix The serum concentration of Relugolix can be increased when it is combined with Piperine.
Tepotinib The serum concentration of Tepotinib can be increased when it is combined with Piperine.
Finerenone The serum concentration of Finerenone can be increased when it is combined with Piperine.
Lemborexant The serum concentration of Lemborexant can be increased when it is combined with Piperine.
Clindamycin The metabolism of Clindamycin can be decreased when combined with Piperine.
Capmatinib The serum concentration of Capmatinib can be increased when it is combined with Piperine.
Selpercatinib The serum concentration of Selpercatinib can be increased when it is combined with Piperine.
Roflumilast The serum concentration of Roflumilast can be increased when it is combined with Piperine.
Loperamide The excretion of Loperamide can be decreased when combined with Piperine.
Enzalutamide The serum concentration of Enzalutamide can be increased when it is combined with Piperine.
Futibatinib The serum concentration of Futibatinib can be increased when it is combined with Piperine.
Dronabinol The serum concentration of Dronabinol can be increased when it is combined with Piperine.
Rilpivirine The serum concentration of Rilpivirine can be increased when it is combined with Piperine.
Tenofovir alafenamide The serum concentration of Tenofovir alafenamide can be increased when it is combined with Piperine.
Clozapine The serum concentration of Clozapine can be increased when it is combined with Piperine.
Doxorubicin The serum concentration of Doxorubicin can be increased when it is combined with Piperine.
Afatinib The serum concentration of Afatinib can be increased when it is combined with Piperine.
Bosutinib The serum concentration of Bosutinib can be increased when it is combined with Piperine.
Brentuximab vedotin The serum concentration of Brentuximab vedotin can be increased when it is combined with Piperine.
Colchicine The serum concentration of Colchicine can be increased when it is combined with Piperine.
Edoxaban The serum concentration of Edoxaban can be increased when it is combined with Piperine.
Ledipasvir The serum concentration of Ledipasvir can be increased when it is combined with Piperine.
Naloxegol The serum concentration of Naloxegol can be increased when it is combined with Piperine.
Pazopanib The serum concentration of Pazopanib can be increased when it is combined with Piperine.
Prucalopride The serum concentration of Prucalopride can be increased when it is combined with Piperine.
Ranolazine The serum concentration of Ranolazine can be increased when it is combined with Piperine.
Silodosin The excretion of Silodosin can be decreased when combined with Piperine.
Topotecan The serum concentration of Topotecan can be increased when it is combined with Piperine.
Eliglustat The metabolism of Eliglustat can be decreased when combined with Piperine.
Ibrutinib The metabolism of Ibrutinib can be decreased when combined with Piperine.
Everolimus The serum concentration of Everolimus can be increased when it is combined with Piperine.
Rifaximin The serum concentration of Rifaximin can be increased when it is combined with Piperine.
Cilostazol The metabolism of Cilostazol can be decreased when combined with Piperine.
Iloperidone The metabolism of Iloperidone can be decreased when combined with Piperine.
Retapamulin The metabolism of Retapamulin can be decreased when combined with Piperine.
Tofacitinib The metabolism of Tofacitinib can be decreased when combined with Piperine.
Vardenafil The metabolism of Vardenafil can be decreased when combined with Piperine.
Eszopiclone The metabolism of Eszopiclone can be decreased when combined with Piperine.
Zopiclone The metabolism of Zopiclone can be decreased when combined with Piperine.
Lovastatin The metabolism of Lovastatin can be decreased when combined with Piperine.
Alfuzosin The metabolism of Alfuzosin can be decreased when combined with Piperine.
Alprazolam The metabolism of Alprazolam can be decreased when combined with Piperine.
Warfarin The serum concentration of Warfarin can be increased when it is combined with Piperine.
Acenocoumarol The serum concentration of Acenocoumarol can be increased when it is combined with Piperine.
(R)-warfarin The serum concentration of (R)-warfarin can be increased when it is combined with Piperine.
R,S-Warfarin alcohol The serum concentration of R,S-Warfarin alcohol can be increased when it is combined with Piperine.
S,R-Warfarin alcohol The serum concentration of S,R-Warfarin alcohol can be increased when it is combined with Piperine.
(S)-Warfarin The serum concentration of (S)-Warfarin can be increased when it is combined with Piperine.
Midazolam The serum concentration of Midazolam can be increased when it is combined with Piperine.
Tacrolimus The serum concentration of Tacrolimus can be increased when it is combined with Piperine.
Atorvastatin The metabolism of Atorvastatin can be decreased when combined with Piperine.
Vincristine The excretion of Vincristine can be decreased when combined with Piperine.
Betrixaban The serum concentration of Betrixaban can be increased when it is combined with Piperine.
Daptomycin The serum concentration of Daptomycin can be increased when it is combined with Piperine.
Cyclosporine The serum concentration of Cyclosporine can be increased when it is combined with Piperine.
Pravastatin The serum concentration of Pravastatin can be increased when it is combined with Piperine.
Bortezomib The serum concentration of Bortezomib can be increased when it is combined with Piperine.
Sildenafil The serum concentration of Sildenafil can be increased when it is combined with Piperine.
Morphine The serum concentration of Morphine can be increased when it is combined with Piperine.
Tenofovir disoproxil The serum concentration of Tenofovir disoproxil can be increased when it is combined with Piperine.
Clobazam The serum concentration of Clobazam can be increased when it is combined with Piperine.
Mefloquine The serum concentration of Mefloquine can be increased when it is combined with Piperine.
Digoxin Piperine may decrease the excretion rate of Digoxin which could result in a higher serum level.
Gemcitabine The serum concentration of Gemcitabine can be increased when it is combined with Piperine.
Quinine The serum concentration of Quinine can be increased when it is combined with Piperine.
Toremifene The serum concentration of Toremifene can be increased when it is combined with Piperine.
Vinblastine The serum concentration of Vinblastine can be increased when it is combined with Piperine.
Bisoprolol The serum concentration of Bisoprolol can be increased when it is combined with Piperine.
Simvastatin The serum concentration of Simvastatin can be increased when it is combined with Piperine.
Verapamil The serum concentration of Verapamil can be increased when it is combined with Piperine.
Mannitol The serum concentration of Mannitol can be increased when it is combined with Piperine.
Etoposide The serum concentration of Etoposide can be increased when it is combined with Piperine.
Sirolimus The serum concentration of Sirolimus can be increased when it is combined with Piperine.
Clomifene The serum concentration of Clomifene can be increased when it is combined with Piperine.
Quinidine The serum concentration of Quinidine can be increased when it is combined with Piperine.
Tipranavir The serum concentration of Tipranavir can be increased when it is combined with Piperine.
Fexofenadine The serum concentration of Fexofenadine can be increased when it is combined with Piperine.
Dactinomycin The serum concentration of Dactinomycin can be increased when it is combined with Piperine.
Tegaserod The serum concentration of Tegaserod can be increased when it is combined with Piperine.
Saquinavir The serum concentration of Saquinavir can be increased when it is combined with Piperine.
Dasatinib The serum concentration of Dasatinib can be increased when it is combined with Piperine.
Sitagliptin The serum concentration of Sitagliptin can be increased when it is combined with Piperine.
Posaconazole The serum concentration of Posaconazole can be increased when it is combined with Piperine.
Darunavir The serum concentration of Darunavir can be increased when it is combined with Piperine.
Paliperidone The serum concentration of Paliperidone can be increased when it is combined with Piperine.
Mibefradil The serum concentration of Mibefradil can be increased when it is combined with Piperine.
Digitoxin The serum concentration of Digitoxin can be increased when it is combined with Piperine.
Belinostat The serum concentration of Belinostat can be increased when it is combined with Piperine.
Indacaterol The serum concentration of Indacaterol can be increased when it is combined with Piperine.
Cobimetinib The serum concentration of Cobimetinib can be increased when it is combined with Piperine.
Telaprevir The serum concentration of Telaprevir can be increased when it is combined with Piperine.
Trastuzumab emtansine The serum concentration of Trastuzumab emtansine can be increased when it is combined with Piperine.

Target Protein

Amine oxidase [flavin-containing] A MAOA
Amine oxidase [flavin-containing] B MAOB
Nuclear receptor subfamily 1 group I member 2 NR1I2

Referensi & Sumber

Belum ada data referensi/link/attachment untuk obat ini pada database. Jalankan import DrugBank untuk mengisi field referensi.

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Sekuens Gen/Protein (FASTA)

Sekuens dimuat saat dibutuhkan agar halaman tetap ringan.
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