AZD-3043

DB12576

small molecule investigational

Deskripsi

AZD3043 has been used in trials studying the treatment and basic science of Safety, Sedation, Tolerability, and Pharmacokinetics.

Struktur Molekul 2D

Berat 351.443
Wujud -

Peta Jejaring Molekuler
Legenda: ObatTargetGenEnzim(Panah → menunjukkan arah efek / relasi)TransporterCarrier

Profil Farmakokinetik

Waktu Paruh (Half-Life) -
Volume Distribusi -
Klirens (Clearance) -

Absorpsi

Data absorpsi tidak tersedia.

Metabolisme

Data metabolisme tidak tersedia.

Rute Eliminasi

Data eliminasi belum tersedia.

Interaksi Obat

665 Data
Buprenorphine AZD-3043 may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Doxylamine Doxylamine may increase the central nervous system depressant (CNS depressant) activities of AZD-3043.
Dronabinol Dronabinol may increase the central nervous system depressant (CNS depressant) activities of AZD-3043.
Droperidol Droperidol may increase the central nervous system depressant (CNS depressant) activities of AZD-3043.
Hydrocodone AZD-3043 may increase the central nervous system depressant (CNS depressant) activities of Hydrocodone.
Hydroxyzine Hydroxyzine may increase the central nervous system depressant (CNS depressant) activities of AZD-3043.
Magnesium sulfate The therapeutic efficacy of AZD-3043 can be increased when used in combination with Magnesium sulfate.
Methotrimeprazine AZD-3043 may increase the central nervous system depressant (CNS depressant) activities of Methotrimeprazine.
Metyrosine AZD-3043 may increase the sedative activities of Metyrosine.
Minocycline Minocycline may increase the central nervous system depressant (CNS depressant) activities of AZD-3043.
Mirtazapine AZD-3043 may increase the central nervous system depressant (CNS depressant) activities of Mirtazapine.
Nabilone Nabilone may increase the central nervous system depressant (CNS depressant) activities of AZD-3043.
Orphenadrine AZD-3043 may increase the central nervous system depressant (CNS depressant) activities of Orphenadrine.
Paraldehyde AZD-3043 may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
Perampanel Perampanel may increase the central nervous system depressant (CNS depressant) activities of AZD-3043.
Pramipexole AZD-3043 may increase the sedative activities of Pramipexole.
Ropinirole AZD-3043 may increase the sedative activities of Ropinirole.
Rotigotine AZD-3043 may increase the sedative activities of Rotigotine.
Rufinamide The risk or severity of adverse effects can be increased when Rufinamide is combined with AZD-3043.
Suvorexant AZD-3043 may increase the central nervous system depressant (CNS depressant) activities of Suvorexant.
Tapentadol Tapentadol may increase the central nervous system depressant (CNS depressant) activities of AZD-3043.
Thalidomide AZD-3043 may increase the central nervous system depressant (CNS depressant) activities of Thalidomide.
Zolpidem AZD-3043 may increase the central nervous system depressant (CNS depressant) activities of Zolpidem.
Methadone The risk or severity of adverse effects can be increased when Methadone is combined with AZD-3043.
Sodium oxybate AZD-3043 may increase the central nervous system depressant (CNS depressant) activities of Sodium oxybate.
Ethanol AZD-3043 may increase the central nervous system depressant (CNS depressant) activities of Ethanol.
Azelastine AZD-3043 may increase the central nervous system depressant (CNS depressant) activities of Azelastine.
Brimonidine Brimonidine may increase the central nervous system depressant (CNS depressant) activities of AZD-3043.
Fluvoxamine The risk or severity of adverse effects can be increased when AZD-3043 is combined with Fluvoxamine.
Citalopram The risk or severity of adverse effects can be increased when AZD-3043 is combined with Citalopram.
Duloxetine The risk or severity of adverse effects can be increased when AZD-3043 is combined with Duloxetine.
Trazodone The risk or severity of adverse effects can be increased when AZD-3043 is combined with Trazodone.
Paroxetine The risk or severity of adverse effects can be increased when AZD-3043 is combined with Paroxetine.
Sertraline The risk or severity of adverse effects can be increased when AZD-3043 is combined with Sertraline.
Sibutramine The risk or severity of adverse effects can be increased when AZD-3043 is combined with Sibutramine.
Nefazodone The risk or severity of adverse effects can be increased when AZD-3043 is combined with Nefazodone.
Escitalopram The risk or severity of adverse effects can be increased when AZD-3043 is combined with Escitalopram.
Zimelidine The risk or severity of adverse effects can be increased when AZD-3043 is combined with Zimelidine.
Dapoxetine The risk or severity of adverse effects can be increased when AZD-3043 is combined with Dapoxetine.
Milnacipran The risk or severity of adverse effects can be increased when AZD-3043 is combined with Milnacipran.
Desvenlafaxine The risk or severity of adverse effects can be increased when AZD-3043 is combined with Desvenlafaxine.
Seproxetine The risk or severity of adverse effects can be increased when AZD-3043 is combined with Seproxetine.
Indalpine The risk or severity of adverse effects can be increased when AZD-3043 is combined with Indalpine.
Ritanserin The risk or severity of adverse effects can be increased when AZD-3043 is combined with Ritanserin.
Alaproclate The risk or severity of adverse effects can be increased when AZD-3043 is combined with Alaproclate.
Amitriptyline The risk or severity of CNS depression can be increased when Amitriptyline is combined with AZD-3043.
Cyproheptadine The risk or severity of CNS depression can be increased when Cyproheptadine is combined with AZD-3043.
Imipramine The risk or severity of CNS depression can be increased when Imipramine is combined with AZD-3043.
Nortriptyline The risk or severity of CNS depression can be increased when Nortriptyline is combined with AZD-3043.
Amoxapine The risk or severity of CNS depression can be increased when Amoxapine is combined with AZD-3043.
Propiomazine The risk or severity of CNS depression can be increased when Propiomazine is combined with AZD-3043.
Maprotiline The risk or severity of CNS depression can be increased when Maprotiline is combined with AZD-3043.
Doxepin The risk or severity of CNS depression can be increased when Doxepin is combined with AZD-3043.
Desipramine The risk or severity of CNS depression can be increased when Desipramine is combined with AZD-3043.
Pizotifen The risk or severity of CNS depression can be increased when Pizotifen is combined with AZD-3043.
Dosulepin The risk or severity of CNS depression can be increased when Dosulepin is combined with AZD-3043.
Zopiclone The risk or severity of adverse effects can be increased when AZD-3043 is combined with Zopiclone.
Botulinum toxin type B The risk or severity of CNS depression can be increased when Botulinum toxin type B is combined with AZD-3043.
Botulinum toxin type A The risk or severity of CNS depression can be increased when Botulinum toxin type A is combined with AZD-3043.
Tryptophan The risk or severity of CNS depression can be increased when Tryptophan is combined with AZD-3043.
Baclofen Baclofen may increase the central nervous system depressant (CNS depressant) activities of AZD-3043.
Lorazepam The risk or severity of CNS depression can be increased when Lorazepam is combined with AZD-3043.
Ethchlorvynol The risk or severity of CNS depression can be increased when Ethchlorvynol is combined with AZD-3043.
Succinylcholine The risk or severity of CNS depression can be increased when Succinylcholine is combined with AZD-3043.
Reserpine The risk or severity of CNS depression can be increased when Reserpine is combined with AZD-3043.
Eletriptan The risk or severity of CNS depression can be increased when Eletriptan is combined with AZD-3043.
Enflurane The risk or severity of CNS depression can be increased when Enflurane is combined with AZD-3043.
Temazepam The risk or severity of CNS depression can be increased when Temazepam is combined with AZD-3043.
Reboxetine The risk or severity of CNS depression can be increased when Reboxetine is combined with AZD-3043.
Butabarbital The risk or severity of CNS depression can be increased when Butabarbital is combined with AZD-3043.
Butalbital The risk or severity of CNS depression can be increased when Butalbital is combined with AZD-3043.
Methysergide The risk or severity of CNS depression can be increased when Methysergide is combined with AZD-3043.
Cabergoline The risk or severity of CNS depression can be increased when Cabergoline is combined with AZD-3043.
Phenytoin The risk or severity of CNS depression can be increased when Phenytoin is combined with AZD-3043.
Topiramate The risk or severity of CNS depression can be increased when Topiramate is combined with AZD-3043.
Clemastine The risk or severity of CNS depression can be increased when Clemastine is combined with AZD-3043.
Venlafaxine The risk or severity of CNS depression can be increased when Venlafaxine is combined with AZD-3043.
Etomidate The risk or severity of CNS depression can be increased when Etomidate is combined with AZD-3043.
Morphine The risk or severity of CNS depression can be increased when Morphine is combined with AZD-3043.
Talbutal The risk or severity of CNS depression can be increased when Talbutal is combined with AZD-3043.
Pentobarbital The risk or severity of CNS depression can be increased when Pentobarbital is combined with AZD-3043.
Valproic acid The risk or severity of CNS depression can be increased when Valproic acid is combined with AZD-3043.
Zolmitriptan The risk or severity of CNS depression can be increased when Zolmitriptan is combined with AZD-3043.
Codeine The risk or severity of CNS depression can be increased when Codeine is combined with AZD-3043.
Dihydroergotamine The risk or severity of CNS depression can be increased when Dihydroergotamine is combined with AZD-3043.
Tolcapone The risk or severity of CNS depression can be increased when Tolcapone is combined with AZD-3043.
Hydromorphone The risk or severity of CNS depression can be increased when Hydromorphone is combined with AZD-3043.
Olanzapine The risk or severity of CNS depression can be increased when Olanzapine is combined with AZD-3043.
Cetirizine The risk or severity of CNS depression can be increased when Cetirizine is combined with AZD-3043.
Protriptyline The risk or severity of CNS depression can be increased when Protriptyline is combined with AZD-3043.
Trimethadione The risk or severity of CNS depression can be increased when Trimethadione is combined with AZD-3043.
Clobazam The risk or severity of sedation, somnolence, and CNS depression can be increased when Clobazam is combined with AZD-3043.
Chlorzoxazone The risk or severity of CNS depression can be increased when Chlorzoxazone is combined with AZD-3043.
Clozapine The risk or severity of CNS depression can be increased when Clozapine is combined with AZD-3043.
Meprobamate The risk or severity of CNS depression can be increased when Meprobamate is combined with AZD-3043.
Thiethylperazine The risk or severity of CNS depression can be increased when Thiethylperazine is combined with AZD-3043.
Palonosetron The risk or severity of CNS depression can be increased when Palonosetron is combined with AZD-3043.
Sulpiride The risk or severity of CNS depression can be increased when Sulpiride is combined with AZD-3043.
Alprazolam The risk or severity of CNS depression can be increased when Alprazolam is combined with AZD-3043.
Dexbrompheniramine The risk or severity of CNS depression can be increased when Dexbrompheniramine is combined with AZD-3043.

Target Protein

Gamma-aminobutyric acid receptor subunit gamma-3 GABRG3

Referensi & Sumber

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Sekuens Gen/Protein (FASTA)

Sekuens dimuat saat dibutuhkan agar halaman tetap ringan.
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