1,2-Benzodiazepine

DB12537

small molecule approved investigational

Deskripsi

Benzodiazepine is under investigation for the prevention of Delirium and C.Surgical Procedure; Cardiac. Benzodiazepine has been investigated for the treatment of Obesity, Sleep Apnea, Obstructive, and Disorders of Gallbladder, Biliary Tract and Pancrease.

Struktur Molekul 2D

Berat 144.177
Wujud -

Peta Jejaring Molekuler
Legenda: ObatTargetGenEnzim(Panah → menunjukkan arah efek / relasi)TransporterCarrier

Profil Farmakokinetik

Waktu Paruh (Half-Life) -
Volume Distribusi -
Klirens (Clearance) -

Absorpsi

Data absorpsi tidak tersedia.

Metabolisme

Data metabolisme tidak tersedia.

Rute Eliminasi

Data eliminasi belum tersedia.

Interaksi Obat

797 Data
Buprenorphine 1,2-Benzodiazepine may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Doxylamine Doxylamine may increase the central nervous system depressant (CNS depressant) activities of 1,2-Benzodiazepine.
Dronabinol Dronabinol may increase the central nervous system depressant (CNS depressant) activities of 1,2-Benzodiazepine.
Droperidol Droperidol may increase the central nervous system depressant (CNS depressant) activities of 1,2-Benzodiazepine.
Hydrocodone 1,2-Benzodiazepine may increase the central nervous system depressant (CNS depressant) activities of Hydrocodone.
Hydroxyzine Hydroxyzine may increase the central nervous system depressant (CNS depressant) activities of 1,2-Benzodiazepine.
Magnesium sulfate The therapeutic efficacy of 1,2-Benzodiazepine can be increased when used in combination with Magnesium sulfate.
Methotrimeprazine 1,2-Benzodiazepine may increase the central nervous system depressant (CNS depressant) activities of Methotrimeprazine.
Metyrosine 1,2-Benzodiazepine may increase the sedative activities of Metyrosine.
Minocycline Minocycline may increase the central nervous system depressant (CNS depressant) activities of 1,2-Benzodiazepine.
Mirtazapine 1,2-Benzodiazepine may increase the central nervous system depressant (CNS depressant) activities of Mirtazapine.
Nabilone Nabilone may increase the central nervous system depressant (CNS depressant) activities of 1,2-Benzodiazepine.
Orphenadrine 1,2-Benzodiazepine may increase the central nervous system depressant (CNS depressant) activities of Orphenadrine.
Paraldehyde 1,2-Benzodiazepine may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
Perampanel Perampanel may increase the central nervous system depressant (CNS depressant) activities of 1,2-Benzodiazepine.
Pramipexole 1,2-Benzodiazepine may increase the sedative activities of Pramipexole.
Ropinirole 1,2-Benzodiazepine may increase the sedative activities of Ropinirole.
Rotigotine 1,2-Benzodiazepine may increase the sedative activities of Rotigotine.
Rufinamide The risk or severity of adverse effects can be increased when Rufinamide is combined with 1,2-Benzodiazepine.
Suvorexant 1,2-Benzodiazepine may increase the central nervous system depressant (CNS depressant) activities of Suvorexant.
Tapentadol Tapentadol may increase the central nervous system depressant (CNS depressant) activities of 1,2-Benzodiazepine.
Thalidomide 1,2-Benzodiazepine may increase the central nervous system depressant (CNS depressant) activities of Thalidomide.
Zolpidem 1,2-Benzodiazepine may increase the central nervous system depressant (CNS depressant) activities of Zolpidem.
Clozapine The risk or severity of adverse effects can be increased when 1,2-Benzodiazepine is combined with Clozapine.
Methadone 1,2-Benzodiazepine may increase the central nervous system depressant (CNS depressant) activities of Methadone.
Olanzapine The risk or severity of adverse effects can be increased when 1,2-Benzodiazepine is combined with Olanzapine.
Sodium oxybate 1,2-Benzodiazepine may increase the central nervous system depressant (CNS depressant) activities of Sodium oxybate.
Teduglutide The serum concentration of 1,2-Benzodiazepine can be increased when it is combined with Teduglutide.
Ethanol 1,2-Benzodiazepine may increase the central nervous system depressant (CNS depressant) activities of Ethanol.
Azelastine 1,2-Benzodiazepine may increase the central nervous system depressant (CNS depressant) activities of Azelastine.
Brimonidine Brimonidine may increase the central nervous system depressant (CNS depressant) activities of 1,2-Benzodiazepine.
Fluvoxamine The risk or severity of adverse effects can be increased when 1,2-Benzodiazepine is combined with Fluvoxamine.
Citalopram The risk or severity of adverse effects can be increased when 1,2-Benzodiazepine is combined with Citalopram.
Duloxetine The risk or severity of adverse effects can be increased when 1,2-Benzodiazepine is combined with Duloxetine.
Trazodone The risk or severity of adverse effects can be increased when 1,2-Benzodiazepine is combined with Trazodone.
Paroxetine The risk or severity of adverse effects can be increased when 1,2-Benzodiazepine is combined with Paroxetine.
Sertraline The risk or severity of adverse effects can be increased when 1,2-Benzodiazepine is combined with Sertraline.
Sibutramine The risk or severity of adverse effects can be increased when 1,2-Benzodiazepine is combined with Sibutramine.
Escitalopram The risk or severity of adverse effects can be increased when 1,2-Benzodiazepine is combined with Escitalopram.
Zimelidine The risk or severity of adverse effects can be increased when 1,2-Benzodiazepine is combined with Zimelidine.
Dapoxetine The risk or severity of adverse effects can be increased when 1,2-Benzodiazepine is combined with Dapoxetine.
Milnacipran The risk or severity of adverse effects can be increased when 1,2-Benzodiazepine is combined with Milnacipran.
Desvenlafaxine The risk or severity of adverse effects can be increased when 1,2-Benzodiazepine is combined with Desvenlafaxine.
Seproxetine The risk or severity of adverse effects can be increased when 1,2-Benzodiazepine is combined with Seproxetine.
Indalpine The risk or severity of adverse effects can be increased when 1,2-Benzodiazepine is combined with Indalpine.
Ritanserin The risk or severity of adverse effects can be increased when 1,2-Benzodiazepine is combined with Ritanserin.
Alaproclate The risk or severity of adverse effects can be increased when 1,2-Benzodiazepine is combined with Alaproclate.
Cyproheptadine The risk or severity of CNS depression can be increased when Cyproheptadine is combined with 1,2-Benzodiazepine.
Amoxapine The risk or severity of CNS depression can be increased when Amoxapine is combined with 1,2-Benzodiazepine.
Propiomazine The risk or severity of CNS depression can be increased when Propiomazine is combined with 1,2-Benzodiazepine.
Maprotiline The risk or severity of CNS depression can be increased when Maprotiline is combined with 1,2-Benzodiazepine.
Desipramine The risk or severity of CNS depression can be increased when Desipramine is combined with 1,2-Benzodiazepine.
Pizotifen The risk or severity of CNS depression can be increased when Pizotifen is combined with 1,2-Benzodiazepine.
Dosulepin The risk or severity of CNS depression can be increased when Dosulepin is combined with 1,2-Benzodiazepine.
Amitriptyline The risk or severity of CNS depression can be increased when Amitriptyline is combined with 1,2-Benzodiazepine.
Imipramine The risk or severity of CNS depression can be increased when Imipramine is combined with 1,2-Benzodiazepine.
Nortriptyline The risk or severity of CNS depression can be increased when Nortriptyline is combined with 1,2-Benzodiazepine.
Nicardipine The metabolism of 1,2-Benzodiazepine can be decreased when combined with Nicardipine.
Doxepin The risk or severity of CNS depression can be increased when Doxepin is combined with 1,2-Benzodiazepine.
Quetiapine The risk or severity of CNS depression can be increased when Quetiapine is combined with 1,2-Benzodiazepine.
Zopiclone The risk or severity of adverse effects can be increased when 1,2-Benzodiazepine is combined with Zopiclone.
Caffeine The therapeutic efficacy of 1,2-Benzodiazepine can be decreased when used in combination with Caffeine.
Dyphylline The therapeutic efficacy of 1,2-Benzodiazepine can be decreased when used in combination with Dyphylline.
Pentoxifylline The therapeutic efficacy of 1,2-Benzodiazepine can be decreased when used in combination with Pentoxifylline.
Mercaptopurine The therapeutic efficacy of 1,2-Benzodiazepine can be decreased when used in combination with Mercaptopurine.
Oxtriphylline The therapeutic efficacy of 1,2-Benzodiazepine can be decreased when used in combination with Oxtriphylline.
Theobromine The therapeutic efficacy of 1,2-Benzodiazepine can be decreased when used in combination with Theobromine.
Fenethylline The therapeutic efficacy of 1,2-Benzodiazepine can be decreased when used in combination with Fenethylline.
8-azaguanine The therapeutic efficacy of 1,2-Benzodiazepine can be decreased when used in combination with 8-azaguanine.
7,9-Dimethylguanine The therapeutic efficacy of 1,2-Benzodiazepine can be decreased when used in combination with 7,9-Dimethylguanine.
Xanthine The therapeutic efficacy of 1,2-Benzodiazepine can be decreased when used in combination with Xanthine.
7-Deazaguanine The therapeutic efficacy of 1,2-Benzodiazepine can be decreased when used in combination with 7-Deazaguanine.
Guanine The therapeutic efficacy of 1,2-Benzodiazepine can be decreased when used in combination with Guanine.
9-Methylguanine The therapeutic efficacy of 1,2-Benzodiazepine can be decreased when used in combination with 9-Methylguanine.
Peldesine The therapeutic efficacy of 1,2-Benzodiazepine can be decreased when used in combination with Peldesine.
Hypoxanthine The therapeutic efficacy of 1,2-Benzodiazepine can be decreased when used in combination with Hypoxanthine.
9-Deazaguanine The therapeutic efficacy of 1,2-Benzodiazepine can be decreased when used in combination with 9-Deazaguanine.
Propentofylline The therapeutic efficacy of 1,2-Benzodiazepine can be decreased when used in combination with Propentofylline.
Valomaciclovir The therapeutic efficacy of 1,2-Benzodiazepine can be decreased when used in combination with Valomaciclovir.
3-isobutyl-1-methyl-7H-xanthine The therapeutic efficacy of 1,2-Benzodiazepine can be decreased when used in combination with 3-isobutyl-1-methyl-7H-xanthine.
Uric acid The therapeutic efficacy of 1,2-Benzodiazepine can be decreased when used in combination with Uric acid.
Doxofylline The therapeutic efficacy of 1,2-Benzodiazepine can be decreased when used in combination with Doxofylline.
6-O-benzylguanine The therapeutic efficacy of 1,2-Benzodiazepine can be decreased when used in combination with 6-O-benzylguanine.
Lisofylline The therapeutic efficacy of 1,2-Benzodiazepine can be decreased when used in combination with Lisofylline.
Lobucavir The therapeutic efficacy of 1,2-Benzodiazepine can be decreased when used in combination with Lobucavir.
Cafedrine The therapeutic efficacy of 1,2-Benzodiazepine can be decreased when used in combination with Cafedrine.
Theodrenaline The therapeutic efficacy of 1,2-Benzodiazepine can be decreased when used in combination with Theodrenaline.
Bamifylline The therapeutic efficacy of 1,2-Benzodiazepine can be decreased when used in combination with Bamifylline.
Proxyphylline The therapeutic efficacy of 1,2-Benzodiazepine can be decreased when used in combination with Proxyphylline.
Acefylline The therapeutic efficacy of 1,2-Benzodiazepine can be decreased when used in combination with Acefylline.
Etamiphylline The therapeutic efficacy of 1,2-Benzodiazepine can be decreased when used in combination with Etamiphylline.
Pentifylline The therapeutic efficacy of 1,2-Benzodiazepine can be decreased when used in combination with Pentifylline.
Bufylline The therapeutic efficacy of 1,2-Benzodiazepine can be decreased when used in combination with Bufylline.
Bromotheophylline The therapeutic efficacy of 1,2-Benzodiazepine can be decreased when used in combination with Bromotheophylline.
Furafylline The therapeutic efficacy of 1,2-Benzodiazepine can be decreased when used in combination with Furafylline.
8-chlorotheophylline The therapeutic efficacy of 1,2-Benzodiazepine can be decreased when used in combination with 8-chlorotheophylline.
PCS-499 The therapeutic efficacy of 1,2-Benzodiazepine can be decreased when used in combination with PCS-499.
Theophylline The therapeutic efficacy of 1,2-Benzodiazepine can be decreased when used in combination with Theophylline.
Aminophylline The therapeutic efficacy of 1,2-Benzodiazepine can be decreased when used in combination with Aminophylline.
Botulinum toxin type B The risk or severity of CNS depression can be increased when Botulinum toxin type B is combined with 1,2-Benzodiazepine.

Target Protein

Translocator protein TSPO
GABA(A) Receptor GABRA1
GABA(A) Receptor Benzodiazepine Binding Site GABRA1

Referensi & Sumber

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Contoh Produk & Brand

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Sekuens Gen/Protein (FASTA)

Sekuens dimuat saat dibutuhkan agar halaman tetap ringan.
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