Lobucavir

DB12531

small molecule investigational

Deskripsi

Lobucavir has been used in trials studying the treatment of HIV Infections and Cytomegalovirus Infections.

Struktur Molekul 2D

Berat 265.273
Wujud -

Peta Jejaring Molekuler
Legenda: ObatTargetGenEnzim(Panah → menunjukkan arah efek / relasi)TransporterCarrier

Profil Farmakokinetik

Waktu Paruh (Half-Life) -
Volume Distribusi -
Klirens (Clearance) -

Absorpsi

Data absorpsi tidak tersedia.

Metabolisme

Data metabolisme tidak tersedia.

Rute Eliminasi

Data eliminasi belum tersedia.

Interaksi Obat

619 Data
Deferasirox The serum concentration of Lobucavir can be increased when it is combined with Deferasirox.
Peginterferon alfa-2b The serum concentration of Lobucavir can be increased when it is combined with Peginterferon alfa-2b.
Leflunomide The serum concentration of Lobucavir can be decreased when it is combined with Leflunomide.
Teriflunomide The serum concentration of Lobucavir can be decreased when it is combined with Teriflunomide.
Regadenoson Lobucavir may decrease effectiveness of Regadenoson as a diagnostic agent.
Adalimumab The serum concentration of Lobucavir can be decreased when it is combined with Adalimumab.
Adenosine The therapeutic efficacy of Adenosine can be decreased when used in combination with Lobucavir.
Allopurinol The serum concentration of Lobucavir can be increased when it is combined with Allopurinol.
Carbamazepine The serum concentration of Lobucavir can be decreased when it is combined with Carbamazepine.
Cimetidine The metabolism of Lobucavir can be decreased when combined with Cimetidine.
Disulfiram The serum concentration of Lobucavir can be increased when it is combined with Disulfiram.
Febuxostat The serum concentration of the active metabolites of Lobucavir can be increased when Lobucavir is used in combination with Febuxostat.
Fluvoxamine The metabolism of Lobucavir can be decreased when combined with Fluvoxamine.
Formoterol The risk or severity of hypokalemia can be increased when Lobucavir is combined with Formoterol.
Indacaterol The risk or severity of adverse effects can be increased when Lobucavir is combined with Indacaterol.
Isoniazid The serum concentration of Lobucavir can be increased when it is combined with Isoniazid.
Lithium citrate The serum concentration of Lithium citrate can be decreased when it is combined with Lobucavir.
Lithium carbonate The serum concentration of Lithium carbonate can be decreased when it is combined with Lobucavir.
Lithium hydroxide The serum concentration of Lithium hydroxide can be decreased when it is combined with Lobucavir.
Mexiletine The metabolism of Lobucavir can be decreased when combined with Mexiletine.
Olodaterol Lobucavir may increase the hyperkalemic activities of Olodaterol.
Pancuronium The therapeutic efficacy of Pancuronium can be decreased when used in combination with Lobucavir.
Pentoxifylline The serum concentration of Lobucavir can be increased when it is combined with Pentoxifylline.
Phenytoin The serum concentration of Lobucavir can be decreased when it is combined with Phenytoin.
Fosphenytoin The serum concentration of Lobucavir can be decreased when it is combined with Fosphenytoin.
Propafenone The serum concentration of Lobucavir can be increased when it is combined with Propafenone.
Quinine The serum concentration of Lobucavir can be increased when it is combined with Quinine.
Quinidine The serum concentration of Lobucavir can be increased when it is combined with Quinidine.
Riociguat Lobucavir may increase the hypotensive activities of Riociguat.
Thiabendazole The metabolism of Lobucavir can be decreased when combined with Thiabendazole.
Ticlopidine The metabolism of Lobucavir can be decreased when combined with Ticlopidine.
Zafirlukast The serum concentration of Zafirlukast can be decreased when it is combined with Lobucavir.
Probenecid The serum concentration of Lobucavir can be increased when it is combined with Probenecid.
Abiraterone The serum concentration of Lobucavir can be increased when it is combined with Abiraterone.
Isoprenaline The serum concentration of Lobucavir can be decreased when it is combined with Isoprenaline.
Cyproterone acetate The metabolism of Lobucavir can be increased when combined with Cyproterone acetate.
Amphetamine The risk or severity of adverse effects can be increased when Amphetamine is combined with Lobucavir.
Phentermine The risk or severity of adverse effects can be increased when Phentermine is combined with Lobucavir.
Midodrine The risk or severity of adverse effects can be increased when Midodrine is combined with Lobucavir.
Norepinephrine The risk or severity of adverse effects can be increased when Norepinephrine is combined with Lobucavir.
Phenylephrine The risk or severity of adverse effects can be increased when Phenylephrine is combined with Lobucavir.
Phenylpropanolamine The risk or severity of adverse effects can be increased when Phenylpropanolamine is combined with Lobucavir.
Labetalol The risk or severity of adverse effects can be increased when Labetalol is combined with Lobucavir.
Metaraminol The risk or severity of adverse effects can be increased when Metaraminol is combined with Lobucavir.
Epinephrine The risk or severity of adverse effects can be increased when Epinephrine is combined with Lobucavir.
Methoxamine The risk or severity of adverse effects can be increased when Methoxamine is combined with Lobucavir.
Orciprenaline The risk or severity of adverse effects can be increased when Orciprenaline is combined with Lobucavir.
Phenmetrazine The risk or severity of adverse effects can be increased when Phenmetrazine is combined with Lobucavir.
Dobutamine The risk or severity of adverse effects can be increased when Dobutamine is combined with Lobucavir.
Pseudoephedrine The risk or severity of adverse effects can be increased when Pseudoephedrine is combined with Lobucavir.
Benzphetamine The risk or severity of adverse effects can be increased when Benzphetamine is combined with Lobucavir.
Ritodrine The risk or severity of adverse effects can be increased when Ritodrine is combined with Lobucavir.
Terbutaline The risk or severity of adverse effects can be increased when Terbutaline is combined with Lobucavir.
Oxymetazoline The risk or severity of adverse effects can be increased when Oxymetazoline is combined with Lobucavir.
Diethylpropion The risk or severity of adverse effects can be increased when Diethylpropion is combined with Lobucavir.
Dopamine The risk or severity of adverse effects can be increased when Dopamine is combined with Lobucavir.
Acebutolol The risk or severity of adverse effects can be increased when Acebutolol is combined with Lobucavir.
Lisdexamfetamine The risk or severity of adverse effects can be increased when Lisdexamfetamine is combined with Lobucavir.
Fenoterol The risk or severity of adverse effects can be increased when Fenoterol is combined with Lobucavir.
Ephedrine The risk or severity of adverse effects can be increased when Ephedrine is combined with Lobucavir.
Mephentermine The risk or severity of adverse effects can be increased when Mephentermine is combined with Lobucavir.
Procaterol The risk or severity of adverse effects can be increased when Procaterol is combined with Lobucavir.
Clenbuterol The risk or severity of adverse effects can be increased when Clenbuterol is combined with Lobucavir.
MMDA The risk or severity of adverse effects can be increased when MMDA is combined with Lobucavir.
Midomafetamine The risk or severity of adverse effects can be increased when Midomafetamine is combined with Lobucavir.
2,5-Dimethoxy-4-ethylamphetamine The risk or severity of adverse effects can be increased when 2,5-Dimethoxy-4-ethylamphetamine is combined with Lobucavir.
4-Bromo-2,5-dimethoxyamphetamine The risk or severity of adverse effects can be increased when 4-Bromo-2,5-dimethoxyamphetamine is combined with Lobucavir.
Tenamfetamine The risk or severity of adverse effects can be increased when Tenamfetamine is combined with Lobucavir.
Chlorphentermine The risk or severity of adverse effects can be increased when Chlorphentermine is combined with Lobucavir.
Methylenedioxyethamphetamine The risk or severity of adverse effects can be increased when Methylenedioxyethamphetamine is combined with Lobucavir.
Dextroamphetamine The risk or severity of adverse effects can be increased when Dextroamphetamine is combined with Lobucavir.
Metamfetamine The risk or severity of adverse effects can be increased when Metamfetamine is combined with Lobucavir.
Celiprolol The risk or severity of adverse effects can be increased when Celiprolol is combined with Lobucavir.
Nylidrin The risk or severity of adverse effects can be increased when Nylidrin is combined with Lobucavir.
Tetryzoline The risk or severity of adverse effects can be increased when Tetryzoline is combined with Lobucavir.
Tyramine The risk or severity of adverse effects can be increased when Tyramine is combined with Lobucavir.
Isoxsuprine The risk or severity of adverse effects can be increased when Isoxsuprine is combined with Lobucavir.
Etilefrine The risk or severity of adverse effects can be increased when Etilefrine is combined with Lobucavir.
Synephrine The risk or severity of adverse effects can be increased when Synephrine is combined with Lobucavir.
Hydroxyamphetamine The risk or severity of adverse effects can be increased when Hydroxyamphetamine is combined with Lobucavir.
Iofetamine I-123 The risk or severity of adverse effects can be increased when Iofetamine I-123 is combined with Lobucavir.
Racepinephrine The risk or severity of adverse effects can be increased when Racepinephrine is combined with Lobucavir.
Ritobegron The risk or severity of adverse effects can be increased when Ritobegron is combined with Lobucavir.
Bucindolol The risk or severity of adverse effects can be increased when Bucindolol is combined with Lobucavir.
Tramazoline The risk or severity of adverse effects can be increased when Tramazoline is combined with Lobucavir.
Mephedrone The risk or severity of adverse effects can be increased when Mephedrone is combined with Lobucavir.
Fenozolone The risk or severity of adverse effects can be increased when Fenozolone is combined with Lobucavir.
Methoxyphenamine The risk or severity of adverse effects can be increased when Methoxyphenamine is combined with Lobucavir.
Tretoquinol The risk or severity of adverse effects can be increased when Tretoquinol is combined with Lobucavir.
Gepefrine The risk or severity of adverse effects can be increased when Gepefrine is combined with Lobucavir.
Epanolol The risk or severity of adverse effects can be increased when Epanolol is combined with Lobucavir.
Prenalterol The risk or severity of adverse effects can be increased when Prenalterol is combined with Lobucavir.
Mefenorex The risk or severity of adverse effects can be increased when Mefenorex is combined with Lobucavir.
2,5-Dimethoxy-4-ethylthioamphetamine The risk or severity of adverse effects can be increased when 2,5-Dimethoxy-4-ethylthioamphetamine is combined with Lobucavir.
Esmolol The risk or severity of adverse effects can be increased when Esmolol is combined with Lobucavir.
Betaxolol The risk or severity of adverse effects can be increased when Betaxolol is combined with Lobucavir.
Metoprolol The risk or severity of adverse effects can be increased when Metoprolol is combined with Lobucavir.
Atenolol The risk or severity of adverse effects can be increased when Atenolol is combined with Lobucavir.
Timolol The risk or severity of adverse effects can be increased when Timolol is combined with Lobucavir.
Sotalol The risk or severity of adverse effects can be increased when Sotalol is combined with Lobucavir.

Target Protein

Gag-Pol polyprotein gag-pol

Referensi & Sumber

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Sekuens Gen/Protein (FASTA)

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