9-aminocamptothecin

DB12515

small molecule investigational

Deskripsi

Aminocamptothecin has been used in trials studying the treatment of Lymphoma, Gastric Cancer, Ovarian Cancer, Esophageal Cancer, and Ovarian Neoplasms, among others.

Struktur Molekul 2D

Berat 363.373
Wujud -

Peta Jejaring Molekuler
Legenda: ObatTargetGenEnzim(Panah → menunjukkan arah efek / relasi)TransporterCarrier

Profil Farmakokinetik

Waktu Paruh (Half-Life) -
Volume Distribusi -
Klirens (Clearance) -

Absorpsi

Data absorpsi tidak tersedia.

Metabolisme

Data metabolisme tidak tersedia.

Rute Eliminasi

Data eliminasi belum tersedia.

Interaksi Obat

520 Data
Phenytoin The metabolism of 9-aminocamptothecin can be increased when combined with Phenytoin.
Fosphenytoin The metabolism of 9-aminocamptothecin can be increased when combined with Fosphenytoin.
Bexarotene The metabolism of 9-aminocamptothecin can be increased when combined with Bexarotene.
Bosentan The metabolism of 9-aminocamptothecin can be increased when combined with Bosentan.
Nafcillin The metabolism of 9-aminocamptothecin can be increased when combined with Nafcillin.
Modafinil The metabolism of 9-aminocamptothecin can be increased when combined with Modafinil.
Etravirine The metabolism of 9-aminocamptothecin can be increased when combined with Etravirine.
Avasimibe The metabolism of 9-aminocamptothecin can be increased when combined with Avasimibe.
Echinacea The metabolism of 9-aminocamptothecin can be increased when combined with Echinacea.
Dexamethasone acetate The metabolism of 9-aminocamptothecin can be increased when combined with Dexamethasone acetate.
Pitolisant The serum concentration of 9-aminocamptothecin can be decreased when it is combined with Pitolisant.
Metreleptin The metabolism of 9-aminocamptothecin can be increased when combined with Metreleptin.
Rifabutin The metabolism of 9-aminocamptothecin can be increased when combined with Rifabutin.
Felbamate The metabolism of 9-aminocamptothecin can be increased when combined with Felbamate.
Genistein The metabolism of 9-aminocamptothecin can be increased when combined with Genistein.
Oritavancin The metabolism of 9-aminocamptothecin can be increased when combined with Oritavancin.
Rufinamide The metabolism of 9-aminocamptothecin can be increased when combined with Rufinamide.
Armodafinil The metabolism of 9-aminocamptothecin can be increased when combined with Armodafinil.
Glycerol phenylbutyrate The metabolism of 9-aminocamptothecin can be increased when combined with Glycerol phenylbutyrate.
Eslicarbazepine acetate The metabolism of 9-aminocamptothecin can be increased when combined with Eslicarbazepine acetate.
Asunaprevir The metabolism of 9-aminocamptothecin can be increased when combined with Asunaprevir.
Sarilumab The metabolism of 9-aminocamptothecin can be increased when combined with Sarilumab.
Lesinurad The metabolism of 9-aminocamptothecin can be increased when combined with Lesinurad.
Esketamine The metabolism of 9-aminocamptothecin can be increased when combined with Esketamine.
Calcitriol The metabolism of 9-aminocamptothecin can be increased when combined with Calcitriol.
Flunisolide The metabolism of 9-aminocamptothecin can be increased when combined with Flunisolide.
Troglitazone The metabolism of 9-aminocamptothecin can be increased when combined with Troglitazone.
Butalbital The metabolism of 9-aminocamptothecin can be increased when combined with Butalbital.
Flucloxacillin The metabolism of 9-aminocamptothecin can be increased when combined with Flucloxacillin.
Acetaminophen The metabolism of 9-aminocamptothecin can be increased when combined with Acetaminophen.
Aminoglutethimide The metabolism of 9-aminocamptothecin can be increased when combined with Aminoglutethimide.
Beclomethasone dipropionate The metabolism of 9-aminocamptothecin can be increased when combined with Beclomethasone dipropionate.
Griseofulvin The metabolism of 9-aminocamptothecin can be increased when combined with Griseofulvin.
Secobarbital The metabolism of 9-aminocamptothecin can be increased when combined with Secobarbital.
Cerivastatin The metabolism of 9-aminocamptothecin can be increased when combined with Cerivastatin.
Betamethasone The metabolism of 9-aminocamptothecin can be increased when combined with Betamethasone.
Quinine The metabolism of 9-aminocamptothecin can be increased when combined with Quinine.
Dicloxacillin The metabolism of 9-aminocamptothecin can be increased when combined with Dicloxacillin.
Rofecoxib The metabolism of 9-aminocamptothecin can be increased when combined with Rofecoxib.
Fluocinolone acetonide The metabolism of 9-aminocamptothecin can be increased when combined with Fluocinolone acetonide.
Medroxyprogesterone acetate The metabolism of 9-aminocamptothecin can be increased when combined with Medroxyprogesterone acetate.
Triamcinolone The metabolism of 9-aminocamptothecin can be increased when combined with Triamcinolone.
Testosterone The metabolism of 9-aminocamptothecin can be increased when combined with Testosterone.
Clofibrate The metabolism of 9-aminocamptothecin can be increased when combined with Clofibrate.
Hydrocortisone The metabolism of 9-aminocamptothecin can be increased when combined with Hydrocortisone.
Hydrocortamate The metabolism of 9-aminocamptothecin can be increased when combined with Hydrocortamate.
Phenylbutazone The metabolism of 9-aminocamptothecin can be increased when combined with Phenylbutazone.
Mifepristone The metabolism of 9-aminocamptothecin can be increased when combined with Mifepristone.
Methylphenobarbital The metabolism of 9-aminocamptothecin can be increased when combined with Methylphenobarbital.
Terbinafine The metabolism of 9-aminocamptothecin can be increased when combined with Terbinafine.
Prednisolone The metabolism of 9-aminocamptothecin can be increased when combined with Prednisolone.
Ethanol The metabolism of 9-aminocamptothecin can be increased when combined with Ethanol.
Norgestimate The metabolism of 9-aminocamptothecin can be increased when combined with Norgestimate.
Methylprednisolone The metabolism of 9-aminocamptothecin can be increased when combined with Methylprednisolone.
Metyrapone The metabolism of 9-aminocamptothecin can be increased when combined with Metyrapone.
Probenecid The metabolism of 9-aminocamptothecin can be increased when combined with Probenecid.
Sulfinpyrazone The metabolism of 9-aminocamptothecin can be increased when combined with Sulfinpyrazone.
Thiamylal The metabolism of 9-aminocamptothecin can be increased when combined with Thiamylal.
Rifapentine The metabolism of 9-aminocamptothecin can be increased when combined with Rifapentine.
Corticotropin The metabolism of 9-aminocamptothecin can be increased when combined with Corticotropin.
Cefradine The metabolism of 9-aminocamptothecin can be increased when combined with Cefradine.
Amobarbital The metabolism of 9-aminocamptothecin can be increased when combined with Amobarbital.
Aprobarbital The metabolism of 9-aminocamptothecin can be increased when combined with Aprobarbital.
Cortisone acetate The metabolism of 9-aminocamptothecin can be increased when combined with Cortisone acetate.
Paramethasone The metabolism of 9-aminocamptothecin can be increased when combined with Paramethasone.
Barbital The metabolism of 9-aminocamptothecin can be increased when combined with Barbital.
Deferasirox The metabolism of 9-aminocamptothecin can be increased when combined with Deferasirox.
Tesmilifene The metabolism of 9-aminocamptothecin can be increased when combined with Tesmilifene.
Clevidipine The metabolism of 9-aminocamptothecin can be increased when combined with Clevidipine.
Isavuconazonium The metabolism of 9-aminocamptothecin can be decreased when combined with Isavuconazonium.
Seratrodast The metabolism of 9-aminocamptothecin can be increased when combined with Seratrodast.
Perampanel The metabolism of 9-aminocamptothecin can be increased when combined with Perampanel.
Formestane The metabolism of 9-aminocamptothecin can be increased when combined with Formestane.
Fluprednidene The metabolism of 9-aminocamptothecin can be increased when combined with Fluprednidene.
Barbexaclone The metabolism of 9-aminocamptothecin can be increased when combined with Barbexaclone.
Meprednisone The metabolism of 9-aminocamptothecin can be increased when combined with Meprednisone.
Dexamethasone isonicotinate The metabolism of 9-aminocamptothecin can be increased when combined with Dexamethasone isonicotinate.
Deflazacort The metabolism of 9-aminocamptothecin can be increased when combined with Deflazacort.
Cortivazol The metabolism of 9-aminocamptothecin can be increased when combined with Cortivazol.
Prednylidene The metabolism of 9-aminocamptothecin can be increased when combined with Prednylidene.
Cloprednol The metabolism of 9-aminocamptothecin can be increased when combined with Cloprednol.
Fluticasone The metabolism of 9-aminocamptothecin can be increased when combined with Fluticasone.
Estradiol acetate The metabolism of 9-aminocamptothecin can be increased when combined with Estradiol acetate.
Estradiol benzoate The metabolism of 9-aminocamptothecin can be increased when combined with Estradiol benzoate.
Estradiol cypionate The metabolism of 9-aminocamptothecin can be increased when combined with Estradiol cypionate.
Estradiol dienanthate The metabolism of 9-aminocamptothecin can be increased when combined with Estradiol dienanthate.
Estradiol valerate The metabolism of 9-aminocamptothecin can be increased when combined with Estradiol valerate.
Mometasone furoate The metabolism of 9-aminocamptothecin can be increased when combined with Mometasone furoate.
Hydrocortisone acetate The metabolism of 9-aminocamptothecin can be increased when combined with Hydrocortisone acetate.
Hydrocortisone succinate The metabolism of 9-aminocamptothecin can be increased when combined with Hydrocortisone succinate.
Prednisolone phosphate The metabolism of 9-aminocamptothecin can be increased when combined with Prednisolone phosphate.
Prednisolone hemisuccinate The metabolism of 9-aminocamptothecin can be increased when combined with Prednisolone hemisuccinate.
Prednisone acetate The metabolism of 9-aminocamptothecin can be increased when combined with Prednisone acetate.
Clocortolone acetate The metabolism of 9-aminocamptothecin can be increased when combined with Clocortolone acetate.
Melengestrol acetate The metabolism of 9-aminocamptothecin can be increased when combined with Melengestrol acetate.
Betamethasone phosphate The metabolism of 9-aminocamptothecin can be increased when combined with Betamethasone phosphate.
Cortisone The metabolism of 9-aminocamptothecin can be increased when combined with Cortisone.
Chlorpromazine The metabolism of 9-aminocamptothecin can be increased when combined with Chlorpromazine.
Clobazam The metabolism of 9-aminocamptothecin can be increased when combined with Clobazam.
Vitamin E The metabolism of 9-aminocamptothecin can be increased when combined with Vitamin E.

Target Protein

DNA topoisomerase 1 TOP1

Referensi & Sumber

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Sekuens Gen/Protein (FASTA)

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