Ketanserin

DB12465

small molecule investigational

Deskripsi

Ketanserin has been investigated for the treatment of Septic Shock, Severe Sepsis, and Diabetic Foot Ulcer.

Struktur Molekul 2D

Berat 395.434
Wujud -

Peta Jejaring Molekuler
Legenda: ObatTargetGenEnzim(Panah → menunjukkan arah efek / relasi)TransporterCarrier

Profil Farmakokinetik

Waktu Paruh (Half-Life) -
Volume Distribusi -
Klirens (Clearance) -

Absorpsi

Data absorpsi tidak tersedia.

Metabolisme

Data metabolisme tidak tersedia.

Rute Eliminasi

Data eliminasi belum tersedia.

Interaksi Obat

50 Data
Tapentadol The risk or severity of serotonin syndrome can be increased when Ketanserin is combined with Tapentadol.
Citalopram The risk or severity of bleeding can be increased when Ketanserin is combined with Citalopram.
Desvenlafaxine The risk or severity of serotonin syndrome can be increased when Desvenlafaxine is combined with Ketanserin.
Levomilnacipran The risk or severity of serotonin syndrome can be increased when Ketanserin is combined with Levomilnacipran.
Avanafil Ketanserin may increase the hypotensive activities of Avanafil.
Venlafaxine The risk or severity of serotonin syndrome can be increased when Ketanserin is combined with Venlafaxine.
Clobazam The risk or severity of sedation, somnolence, and CNS depression can be increased when Clobazam is combined with Ketanserin.
Midazolam The risk or severity of sedation and CNS depression can be increased when Midazolam is combined with Ketanserin.
Baclofen Baclofen may increase the central nervous system depressant (CNS depressant) activities of Ketanserin.
Trazodone The risk or severity of bleeding can be increased when Trazodone is combined with Ketanserin.
Cyclobenzaprine The risk or severity of CNS depression can be increased when Cyclobenzaprine is combined with Ketanserin.
Metoclopramide The risk or severity of sedation can be increased when Metoclopramide is combined with Ketanserin.
Escitalopram The risk or severity of serotonin syndrome can be increased when Ketanserin is combined with Escitalopram.
Quetiapine Quetiapine may increase the hypotensive activities of Ketanserin.
Lasmiditan The risk or severity of serotonin syndrome can be increased when Lasmiditan is combined with Ketanserin.
Sertraline The risk or severity of bleeding can be increased when Sertraline is combined with Ketanserin.
Tramadol The risk or severity of CNS depression can be increased when Ketanserin is combined with Tramadol.
Ziprasidone The risk or severity of adverse effects can be increased when Ketanserin is combined with Ziprasidone.
Cyclothiazide The therapeutic efficacy of Ketanserin can be increased when used in combination with Cyclothiazide.
Trichlormethiazide The therapeutic efficacy of Ketanserin can be increased when used in combination with Trichlormethiazide.
Polythiazide The therapeutic efficacy of Ketanserin can be increased when used in combination with Polythiazide.
Cyclopenthiazide The therapeutic efficacy of Ketanserin can be increased when used in combination with Cyclopenthiazide.
Methyclothiazide The therapeutic efficacy of Ketanserin can be increased when used in combination with Methyclothiazide.
Bendroflumethiazide The therapeutic efficacy of Ketanserin can be increased when used in combination with Bendroflumethiazide.
Hydroflumethiazide The therapeutic efficacy of Ketanserin can be increased when used in combination with Hydroflumethiazide.
Chlorothiazide The therapeutic efficacy of Ketanserin can be increased when used in combination with Chlorothiazide.
Hydrochlorothiazide The therapeutic efficacy of Ketanserin can be increased when used in combination with Hydrochlorothiazide.
Benzthiazide The therapeutic efficacy of Ketanserin can be increased when used in combination with Benzthiazide.
Mebutizide The therapeutic efficacy of Ketanserin can be increased when used in combination with Mebutizide.
Buthiazide The therapeutic efficacy of Ketanserin can be increased when used in combination with Buthiazide.
Haloperidol The risk or severity of CNS depression can be increased when Haloperidol is combined with Ketanserin.
Fluoxetine The risk or severity of serotonin syndrome can be increased when Ketanserin is combined with Fluoxetine.
Indapamide The therapeutic efficacy of Indapamide can be increased when used in combination with Ketanserin.
Fenfluramine The risk or severity of serotonin syndrome can be increased when Ketanserin is combined with Fenfluramine.
Oliceridine The risk or severity of hypotension, sedation, death, somnolence, and respiratory depression can be increased when Ketanserin is combined with Oliceridine.
Vortioxetine The risk or severity of bleeding can be increased when Vortioxetine is combined with Ketanserin.
Serdexmethylphenidate The therapeutic efficacy of Ketanserin can be decreased when used in combination with Serdexmethylphenidate.
Silodosin The risk or severity of orthostatic hypotension and dizziness can be increased when Ketanserin is combined with Silodosin.
Ginkgo biloba Ginkgo biloba may increase the antiplatelet activities of Ketanserin.
Ropeginterferon alfa-2b The risk or severity of neuropsychiatric effects can be increased when Ropeginterferon alfa-2b is combined with Ketanserin.
Daridorexant The risk or severity of CNS depression can be increased when Ketanserin is combined with Daridorexant.
Abrocitinib The risk or severity of bleeding and thrombocytopenia can be increased when Ketanserin is combined with Abrocitinib.
Padeliporfin The risk or severity of bleeding can be increased when Ketanserin is combined with Padeliporfin.
Sodium ferric gluconate complex The risk or severity of hypotension can be increased when Sodium ferric gluconate complex is combined with Ketanserin.
Ganaxolone The risk or severity of sedation, somnolence, and CNS depression can be increased when Ketanserin is combined with Ganaxolone.
Zuranolone The risk or severity of CNS depression can be increased when Zuranolone is combined with Ketanserin.
Lisdexamfetamine The risk or severity of serotonin syndrome can be increased when Ketanserin is combined with Lisdexamfetamine.
Gepirone The risk or severity of serotonin syndrome can be increased when Gepirone is combined with Ketanserin.
Inotersen The risk or severity of thrombocytopenia can be increased when Inotersen is combined with Ketanserin.
Iloprost Iloprost may increase the hypotensive activities of Ketanserin.

Target Protein

5-hydroxytryptamine receptor 2A HTR2A

Referensi & Sumber

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Sekuens Gen/Protein (FASTA)

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