GLPG-0492

DB12461

small molecule investigational

Deskripsi

Glpg0492 is under investigation in clinical trial NCT01130818 (First-in-Human Single Ascending Dose of GLPG0492).

Struktur Molekul 2D

Berat 389.334
Wujud -

Peta Jejaring Molekuler
Legenda: ObatTargetGenEnzim(Panah → menunjukkan arah efek / relasi)TransporterCarrier

Profil Farmakokinetik

Waktu Paruh (Half-Life) -
Volume Distribusi -
Klirens (Clearance) -

Absorpsi

Data absorpsi tidak tersedia.

Metabolisme

Data metabolisme tidak tersedia.

Rute Eliminasi

Data eliminasi belum tersedia.

Interaksi Obat

169 Data
Cyclosporine The risk or severity of liver damage can be increased when GLPG-0492 is combined with Cyclosporine.
Dicoumarol GLPG-0492 may increase the anticoagulant activities of Dicoumarol.
Phenindione GLPG-0492 may increase the anticoagulant activities of Phenindione.
Warfarin GLPG-0492 may increase the anticoagulant activities of Warfarin.
Phenprocoumon GLPG-0492 may increase the anticoagulant activities of Phenprocoumon.
Acenocoumarol GLPG-0492 may increase the anticoagulant activities of Acenocoumarol.
4-hydroxycoumarin GLPG-0492 may increase the anticoagulant activities of 4-hydroxycoumarin.
Coumarin GLPG-0492 may increase the anticoagulant activities of Coumarin.
(R)-warfarin GLPG-0492 may increase the anticoagulant activities of (R)-warfarin.
Ethyl biscoumacetate GLPG-0492 may increase the anticoagulant activities of Ethyl biscoumacetate.
Fluindione GLPG-0492 may increase the anticoagulant activities of Fluindione.
Clorindione GLPG-0492 may increase the anticoagulant activities of Clorindione.
Diphenadione GLPG-0492 may increase the anticoagulant activities of Diphenadione.
Tioclomarol GLPG-0492 may increase the anticoagulant activities of Tioclomarol.
(S)-Warfarin GLPG-0492 may increase the anticoagulant activities of (S)-Warfarin.
Insulin human GLPG-0492 may increase the hypoglycemic activities of Insulin human.
Insulin lispro GLPG-0492 may increase the hypoglycemic activities of Insulin lispro.
Insulin glargine GLPG-0492 may increase the hypoglycemic activities of Insulin glargine.
Insulin pork GLPG-0492 may increase the hypoglycemic activities of Insulin pork.
Troglitazone GLPG-0492 may increase the hypoglycemic activities of Troglitazone.
Glimepiride GLPG-0492 may increase the hypoglycemic activities of Glimepiride.
Sulfisoxazole GLPG-0492 may increase the hypoglycemic activities of Sulfisoxazole.
Disopyramide GLPG-0492 may increase the hypoglycemic activities of Disopyramide.
Acarbose GLPG-0492 may increase the hypoglycemic activities of Acarbose.
Metformin GLPG-0492 may increase the hypoglycemic activities of Metformin.
Sulfadiazine GLPG-0492 may increase the hypoglycemic activities of Sulfadiazine.
Rosiglitazone GLPG-0492 may increase the hypoglycemic activities of Rosiglitazone.
Acetohexamide GLPG-0492 may increase the hypoglycemic activities of Acetohexamide.
Quinine GLPG-0492 may increase the hypoglycemic activities of Quinine.
Miglitol GLPG-0492 may increase the hypoglycemic activities of Miglitol.
Chlorpropamide GLPG-0492 may increase the hypoglycemic activities of Chlorpropamide.
Nateglinide GLPG-0492 may increase the hypoglycemic activities of Nateglinide.
Pentamidine GLPG-0492 may increase the hypoglycemic activities of Pentamidine.
Mifepristone GLPG-0492 may increase the hypoglycemic activities of Mifepristone.
Tolazamide GLPG-0492 may increase the hypoglycemic activities of Tolazamide.
Repaglinide GLPG-0492 may increase the hypoglycemic activities of Repaglinide.
Phenformin GLPG-0492 may increase the hypoglycemic activities of Phenformin.
Sulfamethoxazole GLPG-0492 may increase the hypoglycemic activities of Sulfamethoxazole.
Glyburide GLPG-0492 may increase the hypoglycemic activities of Glyburide.
Glipizide GLPG-0492 may increase the hypoglycemic activities of Glipizide.
Gliclazide GLPG-0492 may increase the hypoglycemic activities of Gliclazide.
Tolbutamide GLPG-0492 may increase the hypoglycemic activities of Tolbutamide.
Pioglitazone GLPG-0492 may increase the hypoglycemic activities of Pioglitazone.
Bromocriptine GLPG-0492 may increase the hypoglycemic activities of Bromocriptine.
Gliquidone GLPG-0492 may increase the hypoglycemic activities of Gliquidone.
Mitiglinide GLPG-0492 may increase the hypoglycemic activities of Mitiglinide.
Sitagliptin GLPG-0492 may increase the hypoglycemic activities of Sitagliptin.
Sunitinib GLPG-0492 may increase the hypoglycemic activities of Sunitinib.
Exenatide GLPG-0492 may increase the hypoglycemic activities of Exenatide.
Mecasermin GLPG-0492 may increase the hypoglycemic activities of Mecasermin.
Pramlintide GLPG-0492 may increase the hypoglycemic activities of Pramlintide.
Glisoxepide GLPG-0492 may increase the hypoglycemic activities of Glisoxepide.
Insulin aspart GLPG-0492 may increase the hypoglycemic activities of Insulin aspart.
Insulin detemir GLPG-0492 may increase the hypoglycemic activities of Insulin detemir.
Insulin glulisine GLPG-0492 may increase the hypoglycemic activities of Insulin glulisine.
Glymidine GLPG-0492 may increase the hypoglycemic activities of Glymidine.
AICA ribonucleotide GLPG-0492 may increase the hypoglycemic activities of AICA ribonucleotide.
Buformin GLPG-0492 may increase the hypoglycemic activities of Buformin.
Vildagliptin GLPG-0492 may increase the hypoglycemic activities of Vildagliptin.
Voglibose GLPG-0492 may increase the hypoglycemic activities of Voglibose.
NN344 GLPG-0492 may increase the hypoglycemic activities of NN344.
AMG-222 GLPG-0492 may increase the hypoglycemic activities of AMG-222.
Bisegliptin GLPG-0492 may increase the hypoglycemic activities of Bisegliptin.
Alogliptin GLPG-0492 may increase the hypoglycemic activities of Alogliptin.
Dapagliflozin GLPG-0492 may increase the hypoglycemic activities of Dapagliflozin.
Saxagliptin GLPG-0492 may increase the hypoglycemic activities of Saxagliptin.
Liraglutide GLPG-0492 may increase the hypoglycemic activities of Liraglutide.
Gosogliptin GLPG-0492 may increase the hypoglycemic activities of Gosogliptin.
Linagliptin GLPG-0492 may increase the hypoglycemic activities of Linagliptin.
Canagliflozin GLPG-0492 may increase the hypoglycemic activities of Canagliflozin.
Glibornuride GLPG-0492 may increase the hypoglycemic activities of Glibornuride.
Benfluorex GLPG-0492 may increase the hypoglycemic activities of Benfluorex.
Empagliflozin GLPG-0492 may increase the hypoglycemic activities of Empagliflozin.
Albiglutide GLPG-0492 may increase the hypoglycemic activities of Albiglutide.
Dulaglutide GLPG-0492 may increase the hypoglycemic activities of Dulaglutide.
Lobeglitazone GLPG-0492 may increase the hypoglycemic activities of Lobeglitazone.
Netoglitazone GLPG-0492 may increase the hypoglycemic activities of Netoglitazone.
Rivoglitazone GLPG-0492 may increase the hypoglycemic activities of Rivoglitazone.
Ciglitazone GLPG-0492 may increase the hypoglycemic activities of Ciglitazone.
Lixisenatide GLPG-0492 may increase the hypoglycemic activities of Lixisenatide.
Insulin beef GLPG-0492 may increase the hypoglycemic activities of Insulin beef.
Insulin degludec GLPG-0492 may increase the hypoglycemic activities of Insulin degludec.
Insulin peglispro GLPG-0492 may increase the hypoglycemic activities of Insulin peglispro.
Insulin tregopil GLPG-0492 may increase the hypoglycemic activities of Insulin tregopil.
Ipragliflozin GLPG-0492 may increase the hypoglycemic activities of Ipragliflozin.
Dutogliptin GLPG-0492 may increase the hypoglycemic activities of Dutogliptin.
Allicin GLPG-0492 may increase the hypoglycemic activities of Allicin.
Tofogliflozin GLPG-0492 may increase the hypoglycemic activities of Tofogliflozin.
Ertugliflozin GLPG-0492 may increase the hypoglycemic activities of Ertugliflozin.
2,4-thiazolidinedione GLPG-0492 may increase the hypoglycemic activities of 2,4-thiazolidinedione.
Teneligliptin GLPG-0492 may increase the hypoglycemic activities of Teneligliptin.
Omarigliptin GLPG-0492 may increase the hypoglycemic activities of Omarigliptin.
Carmegliptin GLPG-0492 may increase the hypoglycemic activities of Carmegliptin.
Gemigliptin GLPG-0492 may increase the hypoglycemic activities of Gemigliptin.
Anagliptin GLPG-0492 may increase the hypoglycemic activities of Anagliptin.
Evogliptin GLPG-0492 may increase the hypoglycemic activities of Evogliptin.
Sotagliflozin GLPG-0492 may increase the hypoglycemic activities of Sotagliflozin.
Balaglitazone GLPG-0492 may increase the hypoglycemic activities of Balaglitazone.
Remogliflozin etabonate GLPG-0492 may increase the hypoglycemic activities of Remogliflozin etabonate.
Carbutamide GLPG-0492 may increase the hypoglycemic activities of Carbutamide.

Target Protein

Androgen receptor AR

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Sekuens Gen/Protein (FASTA)

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