Orvepitant has been used in trials studying the treatment of Depressive Disorder, Depressive Disorder, Major, Post-Traumatic Stress Disorder, and Posttraumatic Stress Disorder (PTSD).
Fitur visualisasi ini dikembangkan menggunakan pendekatan Graph Theory untuk memetakan hubungan polifarmasi dan molekuler. Entitas (Obat, Target, Gen) direpresentasikan sebagai Simpul (Nodes), sedangkan hubungan biologisnya sebagai Sisi (Edges).
drugbank-id dan name pada skema XML DrugBank.targets/target yang memuat polipeptida sasaran.gene-name dan varian snp-effects.Tata letak grafik menggunakan algoritma Force-Directed Graph (Barnes-Hut). Model fisika ini menerapkan gaya tolak-menolak antar simpul (Gravitasi: -3000) agar tidak tumpang tindih, serta gaya pegas (Spring: 0.04) pada garis penghubung untuk fleksibilitas interaksi.
| Buprenorphine | Orvepitant may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine. |
| Doxylamine | Doxylamine may increase the central nervous system depressant (CNS depressant) activities of Orvepitant. |
| Dronabinol | Dronabinol may increase the central nervous system depressant (CNS depressant) activities of Orvepitant. |
| Droperidol | Droperidol may increase the central nervous system depressant (CNS depressant) activities of Orvepitant. |
| Hydrocodone | Orvepitant may increase the central nervous system depressant (CNS depressant) activities of Hydrocodone. |
| Hydroxyzine | Hydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Orvepitant. |
| Magnesium sulfate | The therapeutic efficacy of Orvepitant can be increased when used in combination with Magnesium sulfate. |
| Methotrimeprazine | Orvepitant may increase the central nervous system depressant (CNS depressant) activities of Methotrimeprazine. |
| Metyrosine | Orvepitant may increase the sedative activities of Metyrosine. |
| Minocycline | Minocycline may increase the central nervous system depressant (CNS depressant) activities of Orvepitant. |
| Mirtazapine | Orvepitant may increase the central nervous system depressant (CNS depressant) activities of Mirtazapine. |
| Nabilone | Nabilone may increase the central nervous system depressant (CNS depressant) activities of Orvepitant. |
| Orphenadrine | Orvepitant may increase the central nervous system depressant (CNS depressant) activities of Orphenadrine. |
| Paraldehyde | Orvepitant may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde. |
| Perampanel | Perampanel may increase the central nervous system depressant (CNS depressant) activities of Orvepitant. |
| Pramipexole | Orvepitant may increase the sedative activities of Pramipexole. |
| Ropinirole | Orvepitant may increase the sedative activities of Ropinirole. |
| Rotigotine | Orvepitant may increase the sedative activities of Rotigotine. |
| Rufinamide | The risk or severity of adverse effects can be increased when Rufinamide is combined with Orvepitant. |
| Sodium oxybate | Orvepitant may increase the central nervous system depressant (CNS depressant) activities of Sodium oxybate. |
| Suvorexant | Orvepitant may increase the central nervous system depressant (CNS depressant) activities of Suvorexant. |
| Tapentadol | Tapentadol may increase the central nervous system depressant (CNS depressant) activities of Orvepitant. |
| Thalidomide | Orvepitant may increase the central nervous system depressant (CNS depressant) activities of Thalidomide. |
| Zolpidem | Orvepitant may increase the central nervous system depressant (CNS depressant) activities of Zolpidem. |
| Methadone | The risk or severity of adverse effects can be increased when Methadone is combined with Orvepitant. |
| Dicoumarol | The risk or severity of adverse effects can be increased when Orvepitant is combined with Dicoumarol. |
| Phenindione | The risk or severity of adverse effects can be increased when Orvepitant is combined with Phenindione. |
| Warfarin | The risk or severity of adverse effects can be increased when Orvepitant is combined with Warfarin. |
| Phenprocoumon | The risk or severity of adverse effects can be increased when Orvepitant is combined with Phenprocoumon. |
| Acenocoumarol | The risk or severity of adverse effects can be increased when Orvepitant is combined with Acenocoumarol. |
| 4-hydroxycoumarin | The risk or severity of adverse effects can be increased when Orvepitant is combined with 4-hydroxycoumarin. |
| Coumarin | The risk or severity of adverse effects can be increased when Orvepitant is combined with Coumarin. |
| (R)-warfarin | The risk or severity of adverse effects can be increased when Orvepitant is combined with (R)-warfarin. |
| Ethyl biscoumacetate | The risk or severity of adverse effects can be increased when Orvepitant is combined with Ethyl biscoumacetate. |
| Fluindione | The risk or severity of adverse effects can be increased when Orvepitant is combined with Fluindione. |
| Clorindione | The risk or severity of adverse effects can be increased when Orvepitant is combined with Clorindione. |
| Diphenadione | The risk or severity of adverse effects can be increased when Orvepitant is combined with Diphenadione. |
| Tioclomarol | The risk or severity of adverse effects can be increased when Orvepitant is combined with Tioclomarol. |
| (S)-Warfarin | The risk or severity of adverse effects can be increased when Orvepitant is combined with (S)-Warfarin. |
| Ethanol | Orvepitant may increase the central nervous system depressant (CNS depressant) activities of Ethanol. |
| Azelastine | Orvepitant may increase the central nervous system depressant (CNS depressant) activities of Azelastine. |
| Brimonidine | Brimonidine may increase the central nervous system depressant (CNS depressant) activities of Orvepitant. |
| Fluvoxamine | The risk or severity of adverse effects can be increased when Orvepitant is combined with Fluvoxamine. |
| Citalopram | The risk or severity of adverse effects can be increased when Orvepitant is combined with Citalopram. |
| Duloxetine | The risk or severity of adverse effects can be increased when Orvepitant is combined with Duloxetine. |
| Trazodone | The risk or severity of adverse effects can be increased when Orvepitant is combined with Trazodone. |
| Paroxetine | The risk or severity of adverse effects can be increased when Orvepitant is combined with Paroxetine. |
| Sertraline | The risk or severity of adverse effects can be increased when Orvepitant is combined with Sertraline. |
| Sibutramine | The risk or severity of adverse effects can be increased when Orvepitant is combined with Sibutramine. |
| Nefazodone | The risk or severity of adverse effects can be increased when Orvepitant is combined with Nefazodone. |
| Escitalopram | The risk or severity of adverse effects can be increased when Orvepitant is combined with Escitalopram. |
| Zimelidine | The risk or severity of adverse effects can be increased when Orvepitant is combined with Zimelidine. |
| Dapoxetine | The risk or severity of adverse effects can be increased when Orvepitant is combined with Dapoxetine. |
| Milnacipran | The risk or severity of adverse effects can be increased when Orvepitant is combined with Milnacipran. |
| Desvenlafaxine | The risk or severity of adverse effects can be increased when Orvepitant is combined with Desvenlafaxine. |
| Seproxetine | The risk or severity of adverse effects can be increased when Orvepitant is combined with Seproxetine. |
| Indalpine | The risk or severity of adverse effects can be increased when Orvepitant is combined with Indalpine. |
| Ritanserin | The risk or severity of adverse effects can be increased when Orvepitant is combined with Ritanserin. |
| Alaproclate | The risk or severity of adverse effects can be increased when Orvepitant is combined with Alaproclate. |
| Zopiclone | The risk or severity of adverse effects can be increased when Orvepitant is combined with Zopiclone. |
| Botulinum toxin type B | The risk or severity of CNS depression can be increased when Botulinum toxin type B is combined with Orvepitant. |
| Botulinum toxin type A | The risk or severity of CNS depression can be increased when Botulinum toxin type A is combined with Orvepitant. |
| Tryptophan | The risk or severity of CNS depression can be increased when Tryptophan is combined with Orvepitant. |
| Baclofen | Baclofen may increase the central nervous system depressant (CNS depressant) activities of Orvepitant. |
| Lorazepam | The risk or severity of CNS depression can be increased when Lorazepam is combined with Orvepitant. |
| Ethchlorvynol | The risk or severity of CNS depression can be increased when Ethchlorvynol is combined with Orvepitant. |
| Succinylcholine | The risk or severity of CNS depression can be increased when Succinylcholine is combined with Orvepitant. |
| Reserpine | The risk or severity of CNS depression can be increased when Reserpine is combined with Orvepitant. |
| Eletriptan | The risk or severity of CNS depression can be increased when Eletriptan is combined with Orvepitant. |
| Enflurane | The risk or severity of CNS depression can be increased when Enflurane is combined with Orvepitant. |
| Temazepam | The risk or severity of CNS depression can be increased when Temazepam is combined with Orvepitant. |
| Reboxetine | The risk or severity of CNS depression can be increased when Reboxetine is combined with Orvepitant. |
| Butabarbital | The risk or severity of CNS depression can be increased when Butabarbital is combined with Orvepitant. |
| Butalbital | The risk or severity of CNS depression can be increased when Butalbital is combined with Orvepitant. |
| Methysergide | The risk or severity of CNS depression can be increased when Methysergide is combined with Orvepitant. |
| Cabergoline | The risk or severity of CNS depression can be increased when Cabergoline is combined with Orvepitant. |
| Phenytoin | The risk or severity of CNS depression can be increased when Phenytoin is combined with Orvepitant. |
| Topiramate | The risk or severity of CNS depression can be increased when Topiramate is combined with Orvepitant. |
| Clemastine | The risk or severity of CNS depression can be increased when Clemastine is combined with Orvepitant. |
| Venlafaxine | The risk or severity of CNS depression can be increased when Venlafaxine is combined with Orvepitant. |
| Etomidate | The risk or severity of CNS depression can be increased when Etomidate is combined with Orvepitant. |
| Morphine | The risk or severity of CNS depression can be increased when Morphine is combined with Orvepitant. |
| Talbutal | The risk or severity of CNS depression can be increased when Talbutal is combined with Orvepitant. |
| Pentobarbital | The risk or severity of CNS depression can be increased when Pentobarbital is combined with Orvepitant. |
| Valproic acid | The risk or severity of CNS depression can be increased when Valproic acid is combined with Orvepitant. |
| Zolmitriptan | The risk or severity of CNS depression can be increased when Zolmitriptan is combined with Orvepitant. |
| Codeine | The risk or severity of CNS depression can be increased when Codeine is combined with Orvepitant. |
| Dihydroergotamine | The risk or severity of CNS depression can be increased when Dihydroergotamine is combined with Orvepitant. |
| Amitriptyline | The risk or severity of CNS depression can be increased when Amitriptyline is combined with Orvepitant. |
| Tolcapone | The risk or severity of CNS depression can be increased when Tolcapone is combined with Orvepitant. |
| Hydromorphone | The risk or severity of CNS depression can be increased when Hydromorphone is combined with Orvepitant. |
| Olanzapine | The risk or severity of CNS depression can be increased when Olanzapine is combined with Orvepitant. |
| Cetirizine | The risk or severity of CNS depression can be increased when Cetirizine is combined with Orvepitant. |
| Protriptyline | The risk or severity of CNS depression can be increased when Protriptyline is combined with Orvepitant. |
| Trimethadione | The risk or severity of CNS depression can be increased when Trimethadione is combined with Orvepitant. |
| Clobazam | The risk or severity of sedation, somnolence, and CNS depression can be increased when Clobazam is combined with Orvepitant. |
| Chlorzoxazone | The risk or severity of CNS depression can be increased when Chlorzoxazone is combined with Orvepitant. |
| Clozapine | The risk or severity of CNS depression can be increased when Clozapine is combined with Orvepitant. |
| Meprobamate | The risk or severity of CNS depression can be increased when Meprobamate is combined with Orvepitant. |
| Thiethylperazine | The risk or severity of CNS depression can be increased when Thiethylperazine is combined with Orvepitant. |