Gemigliptin

DB12412

small molecule investigational

Deskripsi

Gemigliptin is under investigation in Type 2 Diabetes Mellitus. Gemigliptin has been investigated for the treatment of Cancer and Cisplatin Adverse Reaction.

Struktur Molekul 2D

Berat 489.37
Wujud -

Peta Jejaring Molekuler
Legenda: ObatTargetGenEnzim(Panah → menunjukkan arah efek / relasi)TransporterCarrier

Profil Farmakokinetik

Waktu Paruh (Half-Life) -
Volume Distribusi -
Klirens (Clearance) -

Absorpsi

Data absorpsi tidak tersedia.

Metabolisme

Data metabolisme tidak tersedia.

Rute Eliminasi

Data eliminasi belum tersedia.

Interaksi Obat

651 Data
Pegvisomant The risk or severity of hypoglycemia can be increased when Pegvisomant is combined with Gemigliptin.
Lipoic acid The risk or severity of hypoglycemia can be increased when Lipoic acid is combined with Gemigliptin.
Moxifloxacin The therapeutic efficacy of Gemigliptin can be increased when used in combination with Moxifloxacin.
Grepafloxacin The therapeutic efficacy of Gemigliptin can be increased when used in combination with Grepafloxacin.
Enoxacin The therapeutic efficacy of Gemigliptin can be increased when used in combination with Enoxacin.
Pefloxacin The therapeutic efficacy of Gemigliptin can be increased when used in combination with Pefloxacin.
Ciprofloxacin The therapeutic efficacy of Gemigliptin can be increased when used in combination with Ciprofloxacin.
Trovafloxacin The therapeutic efficacy of Gemigliptin can be increased when used in combination with Trovafloxacin.
Nalidixic acid The therapeutic efficacy of Gemigliptin can be increased when used in combination with Nalidixic acid.
Rosoxacin The therapeutic efficacy of Gemigliptin can be increased when used in combination with Rosoxacin.
Cinoxacin The therapeutic efficacy of Gemigliptin can be increased when used in combination with Cinoxacin.
Lomefloxacin The therapeutic efficacy of Gemigliptin can be increased when used in combination with Lomefloxacin.
Gatifloxacin The therapeutic efficacy of Gemigliptin can be increased when used in combination with Gatifloxacin.
Norfloxacin The therapeutic efficacy of Gemigliptin can be increased when used in combination with Norfloxacin.
Levofloxacin The therapeutic efficacy of Gemigliptin can be increased when used in combination with Levofloxacin.
Gemifloxacin The therapeutic efficacy of Gemigliptin can be increased when used in combination with Gemifloxacin.
Ofloxacin The therapeutic efficacy of Gemigliptin can be increased when used in combination with Ofloxacin.
Sparfloxacin The therapeutic efficacy of Gemigliptin can be increased when used in combination with Sparfloxacin.
Temafloxacin The therapeutic efficacy of Gemigliptin can be increased when used in combination with Temafloxacin.
Fleroxacin The therapeutic efficacy of Gemigliptin can be increased when used in combination with Fleroxacin.
Technetium Tc-99m ciprofloxacin The therapeutic efficacy of Gemigliptin can be increased when used in combination with Technetium Tc-99m ciprofloxacin.
Garenoxacin The therapeutic efficacy of Gemigliptin can be increased when used in combination with Garenoxacin.
Nemonoxacin The therapeutic efficacy of Gemigliptin can be increased when used in combination with Nemonoxacin.
Flumequine The therapeutic efficacy of Gemigliptin can be increased when used in combination with Flumequine.
Enrofloxacin The therapeutic efficacy of Gemigliptin can be increased when used in combination with Enrofloxacin.
Orbifloxacin The therapeutic efficacy of Gemigliptin can be increased when used in combination with Orbifloxacin.
Sarafloxacin The therapeutic efficacy of Gemigliptin can be increased when used in combination with Sarafloxacin.
Difloxacin The therapeutic efficacy of Gemigliptin can be increased when used in combination with Difloxacin.
Pazufloxacin The therapeutic efficacy of Gemigliptin can be increased when used in combination with Pazufloxacin.
Prulifloxacin The therapeutic efficacy of Gemigliptin can be increased when used in combination with Prulifloxacin.
Delafloxacin The therapeutic efficacy of Gemigliptin can be increased when used in combination with Delafloxacin.
Sitafloxacin The therapeutic efficacy of Gemigliptin can be increased when used in combination with Sitafloxacin.
Oxolinic acid The therapeutic efficacy of Gemigliptin can be increased when used in combination with Oxolinic acid.
Rufloxacin The therapeutic efficacy of Gemigliptin can be increased when used in combination with Rufloxacin.
Pipemidic acid The therapeutic efficacy of Gemigliptin can be increased when used in combination with Pipemidic acid.
Methyclothiazide The therapeutic efficacy of Gemigliptin can be decreased when used in combination with Methyclothiazide.
Chlorthalidone The therapeutic efficacy of Gemigliptin can be decreased when used in combination with Chlorthalidone.
Bendroflumethiazide The therapeutic efficacy of Gemigliptin can be decreased when used in combination with Bendroflumethiazide.
Metolazone The therapeutic efficacy of Gemigliptin can be decreased when used in combination with Metolazone.
Benzthiazide The therapeutic efficacy of Gemigliptin can be decreased when used in combination with Benzthiazide.
Hydroflumethiazide The therapeutic efficacy of Gemigliptin can be decreased when used in combination with Hydroflumethiazide.
Indapamide The therapeutic efficacy of Gemigliptin can be decreased when used in combination with Indapamide.
Chlorothiazide The therapeutic efficacy of Gemigliptin can be decreased when used in combination with Chlorothiazide.
Hydrochlorothiazide The therapeutic efficacy of Gemigliptin can be decreased when used in combination with Hydrochlorothiazide.
Trichlormethiazide The therapeutic efficacy of Gemigliptin can be decreased when used in combination with Trichlormethiazide.
Polythiazide The therapeutic efficacy of Gemigliptin can be decreased when used in combination with Polythiazide.
Quinethazone The therapeutic efficacy of Gemigliptin can be decreased when used in combination with Quinethazone.
Cyclopenthiazide The therapeutic efficacy of Gemigliptin can be decreased when used in combination with Cyclopenthiazide.
Epitizide The therapeutic efficacy of Gemigliptin can be decreased when used in combination with Epitizide.
Amitriptyline Amitriptyline may decrease the hypoglycemic activities of Gemigliptin.
Protriptyline Protriptyline may decrease the hypoglycemic activities of Gemigliptin.
Imipramine Imipramine may decrease the hypoglycemic activities of Gemigliptin.
Nortriptyline Nortriptyline may decrease the hypoglycemic activities of Gemigliptin.
Amoxapine Amoxapine may decrease the hypoglycemic activities of Gemigliptin.
Trimipramine Trimipramine may decrease the hypoglycemic activities of Gemigliptin.
Doxepin Doxepin may decrease the hypoglycemic activities of Gemigliptin.
Desipramine Desipramine may decrease the hypoglycemic activities of Gemigliptin.
Clomipramine Clomipramine may decrease the hypoglycemic activities of Gemigliptin.
Amineptine Amineptine may decrease the hypoglycemic activities of Gemigliptin.
Dimetacrine Dimetacrine may decrease the hypoglycemic activities of Gemigliptin.
Butriptyline Butriptyline may decrease the hypoglycemic activities of Gemigliptin.
Dosulepin Dosulepin may decrease the hypoglycemic activities of Gemigliptin.
Tianeptine Tianeptine may decrease the hypoglycemic activities of Gemigliptin.
Oxaprotiline Oxaprotiline may decrease the hypoglycemic activities of Gemigliptin.
Opipramol Opipramol may decrease the hypoglycemic activities of Gemigliptin.
Amitriptylinoxide Amitriptylinoxide may decrease the hypoglycemic activities of Gemigliptin.
Dibenzepin Dibenzepin may decrease the hypoglycemic activities of Gemigliptin.
Quinupramine Quinupramine may decrease the hypoglycemic activities of Gemigliptin.
Melitracen Melitracen may decrease the hypoglycemic activities of Gemigliptin.
Lofepramine Lofepramine may decrease the hypoglycemic activities of Gemigliptin.
Iprindole Iprindole may decrease the hypoglycemic activities of Gemigliptin.
Imipramine oxide Imipramine oxide may decrease the hypoglycemic activities of Gemigliptin.
Glimepiride Gemigliptin may increase the hypoglycemic activities of Glimepiride.
Acetohexamide Gemigliptin may increase the hypoglycemic activities of Acetohexamide.
Chlorpropamide Gemigliptin may increase the hypoglycemic activities of Chlorpropamide.
Tolazamide Gemigliptin may increase the hypoglycemic activities of Tolazamide.
Glyburide Gemigliptin may increase the hypoglycemic activities of Glyburide.
Glipizide Gemigliptin may increase the hypoglycemic activities of Glipizide.
Gliclazide Gemigliptin may increase the hypoglycemic activities of Gliclazide.
Tolbutamide Gemigliptin may increase the hypoglycemic activities of Tolbutamide.
Gliquidone Gemigliptin may increase the hypoglycemic activities of Gliquidone.
Glisoxepide Gemigliptin may increase the hypoglycemic activities of Glisoxepide.
Glibornuride Gemigliptin may increase the hypoglycemic activities of Glibornuride.
Carbutamide Gemigliptin may increase the hypoglycemic activities of Carbutamide.
Metahexamide Gemigliptin may increase the hypoglycemic activities of Metahexamide.
Dapagliflozin Dapagliflozin may increase the hypoglycemic activities of Gemigliptin.
Canagliflozin Canagliflozin may increase the hypoglycemic activities of Gemigliptin.
Leuprolide The therapeutic efficacy of Gemigliptin can be decreased when used in combination with Leuprolide.
Goserelin The therapeutic efficacy of Gemigliptin can be decreased when used in combination with Goserelin.
Nelfinavir The therapeutic efficacy of Gemigliptin can be decreased when used in combination with Nelfinavir.
Indinavir The therapeutic efficacy of Gemigliptin can be decreased when used in combination with Indinavir.
Ziprasidone The therapeutic efficacy of Gemigliptin can be decreased when used in combination with Ziprasidone.
Etonogestrel The therapeutic efficacy of Gemigliptin can be decreased when used in combination with Etonogestrel.
Desogestrel The therapeutic efficacy of Gemigliptin can be decreased when used in combination with Desogestrel.
Olanzapine The therapeutic efficacy of Gemigliptin can be decreased when used in combination with Olanzapine.
Megestrol acetate The therapeutic efficacy of Gemigliptin can be decreased when used in combination with Megestrol acetate.
Clozapine The therapeutic efficacy of Gemigliptin can be decreased when used in combination with Clozapine.
Levonorgestrel The therapeutic efficacy of Gemigliptin can be decreased when used in combination with Levonorgestrel.
Progesterone The therapeutic efficacy of Gemigliptin can be decreased when used in combination with Progesterone.
Chlorpromazine The therapeutic efficacy of Gemigliptin can be decreased when used in combination with Chlorpromazine.

Target Protein

Dipeptidyl peptidase 4 DPP4

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Sekuens Gen/Protein (FASTA)

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